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Senior Bioinformatics Scientist Jobs (NOW HIRING)

BiomeSense

Senior Bioinformatics Engineer

Chicago, IL · On-site

$125K - $200K/yr

Senior Bioinformatics Engineer Compensation: $125K - $200K base + 0.25% - 0.5% equity stock options About BiomeSense BiomeSense is a life sciences startup applying gut microbiome (GMB) technologies ...

BiomeSense

Senior Bioinformatics Engineer

Chicago, IL · On-site

BiomeSense is a pioneering life sciences startup focused on harnessing the power of the gut microbiome to revolutionize personalized medicine. The Senior Bioinformatics Engineer will help build the ...

Bruker

This role reports to our Senior Bioinformatician and does not include management of direct reports ... Communicate findings to scientists, researchers, and stakeholders through clear written reports and ...

UNAVAILABLE

Scientist, Bioinformatics

Saint Louis, MO

This role reports to our Senior Bioinformatician and does not include management of direct reports ... Communicate findings to scientists, researchers, and stakeholders through clear written reports and ...

Bruker

Scientist, Bioinformatics

Saint Louis, MO

This role reports to our Senior Bioinformatician and does not include management of direct reports ... Communicate findings to scientists, researchers, and stakeholders through clear written reports and ...

UNAVAILABLE

This role reports to our Senior Bioinformatician and does not include management of direct reports ... Communicate findings to scientists, researchers, and stakeholders through clear written reports and ...

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Senior Bioinformatics Scientist information

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$101.4K

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How much do senior bioinformatics scientist jobs pay per year?

As of Jul 26, 2026, the average yearly pay for senior bioinformatics scientist in the United States is $101,443.00, according to ZipRecruiter salary data. Most workers in this role earn between $57,500.00 and $137,500.00 per year, depending on experience, location, and employer.

What are the primary responsibilities of a Senior Bioinformatics Scientist on a day-to-day basis?

Senior Bioinformatics Scientists typically design and implement analytical workflows to process large-scale biological datasets, such as genomic or transcriptomic data. They frequently collaborate with laboratory scientists and research teams to interpret results and guide experimental design. Additional responsibilities often include developing custom software tools, publishing research findings, mentoring junior team members, and staying updated on emerging technologies in the field. This combination of tasks ensures both the quality of analyses and the continuous innovation within research projects.

What are the key skills and qualifications needed to thrive in the Senior Bioinformatics Scientist position, and why are they important?

To thrive as a Senior Bioinformatics Scientist, you need expertise in computational biology, data analysis, and molecular biology, typically with an advanced degree such as a PhD in bioinformatics, computational biology, or a related field. Familiarity with programming languages (such as Python, R), bioinformatics pipelines, databases, and experience with high-performance computing environments is crucial. Strong problem-solving skills, effective communication, and the ability to lead cross-disciplinary teams are key soft skills in this role. These abilities ensure accurate data interpretation, successful project collaboration, and advancement of scientific research initiatives.

What does a Senior Bioinformatics Scientist do?

A Senior Bioinformatics Scientist analyzes complex biological data using computational tools and algorithms, often focusing on genomics, proteomics, or transcriptomics. They design and implement bioinformatics pipelines, develop software solutions, and collaborate with biologists to interpret results. Their role includes managing large datasets, optimizing data processing workflows, and contributing to scientific publications. Additionally, they may mentor junior scientists and lead research projects to advance biological discoveries.

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Senior Bioinformatics Scientist jobs near you
Infographic showing various Senior Bioinformatics Scientist job openings in the United States as of July 2026, with employment types broken down into 9% As Needed, 75% Full Time, 12% Part Time, 2% Contract, 1% Nights, and 1% Summer. Highlights an 80% Physical, 3% Hybrid, and 17% Remote job distribution, with an average salary of $101,443 per year, or $48.8 per hour.
Senior Staff Engineer/Scientist, Bioinformatics

Senior Staff Engineer/Scientist, Bioinformatics

Foresite Labs

San Diego, CA • On-site

$202K - $215K/yr

Full-time

Posted 4 days ago

Job description

Job Title: Senior Staff Engineer, Bioinformatics
Location: San Diego, CA
Job Type: Full-Time
Salary $202,000-$215,000
Position Overview
The Senior Staff Engineer, Bioinformatics will develop, advance, and support large-scale analysis of multi-omic data, through application of existing and novel methods. They will be responsible for developing scalable pipelines for cloud and HPC environments. The ideal candidate combines strong expertise in data science and software development, along with the ability to work cross-functionally with wet-lab and commercial teams.
Key Responsibilities
  • Analyze large-scale multi-omic data to delineate technical artifacts from biological signals.
  • Design and implement novel computational methods to improve signal detection and reduce compute costs.
  • Develop and maintain robust analysis pipelines.
  • Build and optimize reproducible workflows in cloud and HPC environments with attention to cost and scalability.
  • Identify and resolve technical artifacts through cohort-level and assay-aware analysis.
  • Partner with wet-lab scientists to diagnose and address assay artifacts.
  • Communicate findings clearly and contribute to technical decision-making.

Qualifications
Education:
  • Ph.D. in computational biology, computer science, statistics, genomics, or related field

Required:
  • 6+ years of professional experience in bioinformatics or closely related roles.
  • Ability to distinguish biological signal from technical noise using a variety of statistical, machine learning and deep learning methodologies.
  • Proficiency in programming languages frequently used for both ad hoc and scalable production multi-omic analyses.
  • Experience developing reproducible workflows in cloud or HPC environments.

Preferred:
  • Experience optimizing compute costs at scale
  • Experience developing commercial products

Why Join Us
  • Work in a dynamic, collaborative environment where innovation and scientific rigor are deeply valued.
  • Join a seasoned and multidisciplinary team tackling high-impact problems at the intersection of science and engineering.
  • Competitive compensation and equity package, comprehensive benefits, and flexibility to support work-life integration.

We are an equal opportunity employer. We thrive on diversity and collaboration.

Apply