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How much do senior bioinformatics scientist jobs pay per year?

As of Sep 2, 2026, the average yearly pay for senior bioinformatics scientist in the United States is $101,443.00, according to ZipRecruiter salary data. Most workers in this role earn between $57,500.00 and $137,500.00 per year, depending on experience, location, and employer.

What does a senior bioinformatics scientist do?

A Senior Bioinformatics Scientist analyzes complex biological data using computational tools and algorithms, often focusing on genomics, proteomics, or transcriptomics. They design and implement bioinformatics pipelines, develop software solutions, and collaborate with biologists to interpret results. Their role includes managing large datasets, optimizing data processing workflows, and contributing to scientific publications. Additionally, they may mentor junior scientists and lead research projects to advance biological discoveries.

What are the key skills and qualifications needed to thrive as a senior bioinformatics scientist?

To thrive as a Senior Bioinformatics Scientist, you need expertise in computational biology, data analysis, and molecular biology, typically with an advanced degree such as a PhD in bioinformatics, computational biology, or a related field. Familiarity with programming languages (such as Python, R), bioinformatics pipelines, databases, and experience with high-performance computing environments is crucial. Strong problem-solving skills, effective communication, and the ability to lead cross-disciplinary teams are key soft skills in this role. These abilities ensure accurate data interpretation, successful project collaboration, and advancement of scientific research initiatives.

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Infographic showing various Senior Bioinformatics Scientist job openings in the United States as of August 2026, with employment types broken down into 1% Internship, 1% As Needed, 91% Full Time, 4% Part Time, and 3% Contract. Highlights an 89% Physical, 3% Hybrid, and 8% Remote job distribution, with an average salary of $101,443 per year, or $48.8 per hour.

Senior Bioinformatics Research Scientist

St. Jude Children's Research Hospital

Memphis, TN • On-site

Full-time

Posted 17 days ago


St. Jude Children's Research Hospital rating

8.6

Company rating: 8.6 out of 10

Based on 12 frontline employees who took The Breakroom Quiz

42nd of 1,064 rated hospitals


Job description

St. Jude is seeking a Senior Bioinformatics Research Scientist for data science projects within the Center for Pharmacogenomics in the Department of Pharmacy and Pharmaceutical Sciences. In particular, this individual will focus on electronic health record (EHR)-driven phenotyping to support pharmacogenomics discovery research.
The successful candidate will be responsible for developing and implementing new informatics tools and resources to enhance phenotyping performance or enable deep phenotyping through terminology/ontology, natural language processing, and machine learning. The role involves working with large external biobank datasets such as All of US, eMERGE, TopMed, UK BioBank, as well internal EHR data.
This Bioinformatics Research Scientist will collaborate extensively with disease and/or drug experts (clinicians, clinician scientists, data scientists, and laboratory investigators) to co-develop phenotyping algorithms but is expected to serve as the domain expert in high-throughput phenotyping.
Demonstrated expertise in EHR-based phenotype extraction and curation are strongly preferred.
Responsibilities
oProvide research support and deliver high-quality results by formulating an efficient analytical approach with the available data.
oDeliver data files, and document the analytical process. May participate in manuscript preparation at project's conclusion.
oAssist with establishing and documenting protocols or best practices for common research tasks, and in the formulation of analytical plans that use the best approach to address challenging data analysis questions.
oAssist in the evaluation and testing of new methods and technologies.
oContribute ideas to automate or improve existing analysis methods. Implement the improvement or work with others to do so.
oParticipate in the department's developmental projects and interdepartmental team projects.
Qualifications
oMinimum Requirement: Bachelor's degree with 7+ years of relevant post-degree work experience in relevant area (e.g., bioinformatics, cheminformatics, statistics/computer science with a background in biological sciences or chemistry) (OR) Master's degree with 5+ years of relevant experience (OR) PhD with 2+ years of relevant experience.
oSignificant experience in at least one programming or scripting language and at least one statistical package, with R preferred.
As one of the premier pediatric research institutions in the world, St. Jude Children's Research Hospital provides exceptional resources and a supportive environment for career development. In this position, the candidate will interact with leaders in pharmacogenomics and data science in general within and outside the institution and at national/international meetings. Innovation and independence are encouraged with the goal of providing flexibility and freedom in exploring new directions.
Job Responsibilities:
  • Provide research support and deliver high-quality results by formulating an efficient analytical approach with the available data.
  • Deliver data files, and document the analytical process. May participate in manuscript preparation at project's conclusion.
  • Assist with establishing and documenting protocols or best practices for common research tasks, and in the formulation of analytical plans that use the best approach to address challenging data analysis questions.
  • Assist in the evaluation and testing of new methods and technologies.
  • Contribute ideas to automate or improve existing analysis methods. Implement the improvement or work with others to do so.
  • Participate in the department's developmental projects and interdepartmental team projects.
  • Perform other duties as assigned to meet the goals and objectives of the department and institution.
  • Maintains regular and predictable attendance.
  • Provide research support and deliver high-quality results by formulating an efficient analytical approach with the available data.
  • Deliver data files, and document the analytical process. May participate in manuscript preparation at project's conclusion.
  • Assist with establishing and documenting protocols or best practices for common research tasks, and in the formulation of analytical plans that use the best approach to address challenging data analysis questions.
  • Assist in the evaluation and testing of new methods and technologies.
  • Contribute ideas to automate or improve existing analysis methods. Implement the improvement or work with others to do so.
  • Participate in the department's developmental projects and interdepartmental team projects.

Minimum Education and/or Training:
  • Bachelor's degree in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry) or related field.
  • Master's degree or PhD preferred.

Minimum Experience:
  • Minimum Requirement: Bachelor's degree with 7+ years of relevant post-degree work in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry).
  • Experience Exception: Master's degree with 5+ years of relevant post-degree experience (OR) PhD with 2+ years of relevant post-degree experience.
  • Significant experience in at least one programming or scripting language and at least one statistical package, with R preferred.

Compensation
In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $104,000 - $186,160 per year for the role of Senior Bioinformatics Research Scientist.
Explore our exceptional benefits!
St. Jude is an Equal Opportunity Employer
No Search Firms
St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

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