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Senior Computational Scientist Jobs (NOW HIRING)

University of Alabama at Birmingham

$86 - $139/hr

- COMPUTATIONAL SCIENTIST (T238342) COMPUTATIONAL SCIENTIST - ( T238342 ) Description COMPUTATIONAL ... Individuals may report concerns or questions to UAB's Assistant Vice President and Senior Title IX ...

UAB NOVA RENT

COMPUTATIONAL SCIENTIST

Birmingham, AL · On-site

$85K - $139K/yr

COMPUTATIONAL SCIENTIST University of Alabama at Birmingham The Department of Anesthesiology and ... Individuals may report concerns or questions to UAB's Assistant Vice President and Senior Title IX ...

UAB NOVA RENT

COMPUTATIONAL SCIENTIST

Birmingham, AL · On-site

$85K - $139K/yr

COMPUTATIONAL SCIENTIST University of Alabama at Birmingham The Department of Anesthesiology and ... Individuals may report concerns or questions to UAB's Assistant Vice President and Senior Title IX ...

UAB

COMPUTATIONAL SCIENTIST

Tampa, FL

$85K - $139K/yr

COMPUTATIONAL SCIENTIST University of Alabama at Birmingham The Department of Anesthesiology and ... Individuals may report concerns or questions to UAB's Assistant Vice President and Senior Title IX ...

UAB

COMPUTATIONAL SCIENTIST

Tampa, FL

$85K - $139K/yr

COMPUTATIONAL SCIENTIST University of Alabama at Birmingham The Department of Anesthesiology and ... Individuals may report concerns or questions to UAB's Assistant Vice President and Senior Title IX ...

Pfizer

Senior Computational Chemist

California, MO · On-site

$106 - $177/hr

Contribute to the scientific culture of MLCS through knowledge sharing, internal talks, and cross-team collaboration.## Required Qualifications* Ph.D. in Computational Chemistry, Cheminformatics ...

Pfizer

Senior Computational Chemist

La Jolla, CA · On-site +1

$106K - $176K/yr

Position Summary The Machine Learning & Computational Sciences (MLCS) organization within Medicine ... We are seeking a Senior Computational Chemist with a strong cheminformatics background and a proven ...

Voltai, Inc

Computational Scientist

Palo Alto, CA · On-site

... Senior Foreign-Policy Advisor to four US presidents. What You'll Work On * Develop and scale MPI ... PhD in computational physics, applied mathematics, computational engineering, or a closely related ...

Pfizer, Inc.

Senior Computational Chemist

La Jolla, CA · On-site

$106K - $176K/yr

Position Summary The Machine Learning & Computational Sciences (MLCS) organization within Medicine ... We are seeking a Senior Computational Chemist with a strong cheminformatics background and a proven ...

Thecentermemphis

$86 - $155/hr

Develop, deploy, optimize, and maintain scientific applications, computational, and visualization tools, data processing pipelines, and programming libraries on HPCF systems * Support investigators ...

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Senior Computational Scientist information

See salary details

$50.5K

$111.3K

$137.5K

How much do senior computational scientist jobs pay per year?

As of Aug 26, 2026, the average yearly pay for senior computational scientist in the United States is $111,343.00, according to ZipRecruiter salary data. Most workers in this role earn between $94,500.00 and $137,000.00 per year, depending on experience, location, and employer.

What does a senior computational scientist do?

A Senior Computational Scientist develops and applies advanced computational methods to solve complex scientific and engineering problems. They design algorithms, create simulations, and analyze large datasets, often working in interdisciplinary teams. Their work supports research and development in fields like bioinformatics, physics, chemistry, and engineering. Additionally, they may mentor junior scientists, contribute to scientific publications, and help set technical directions for their organization.

What are the key skills and qualifications needed to thrive as a senior computational scientist?

To thrive as a Senior Computational Scientist, you need advanced expertise in computational methods, statistical analysis, programming (such as Python or R), and typically a Ph.D. or equivalent experience in a quantitative field. Familiarity with high-performance computing environments, scientific software (e.g., MATLAB, TensorFlow), and version control systems is commonly required. Strong problem-solving abilities, leadership, and effective communication help in collaborating across multidisciplinary teams and managing complex projects. These skills are critical for developing innovative computational solutions and driving impactful research outcomes.

How does a senior computational scientist typically collaborate with interdisciplinary teams in research projects?

Senior Computational Scientists frequently work alongside experts from fields such as biology, physics, engineering, and data science. They are responsible for translating complex scientific questions into computational models, guiding data analysis, and ensuring that computational methods align with project goals. Effective communication and project management skills are essential, as these professionals often lead discussions, present findings, and coordinate technical solutions across varied teams. This collaborative environment fosters innovation and allows for continuous learning from diverse scientific perspectives.

What is the difference between Senior Computational Scientist vs Computational Scientist?

AspectSenior Computational ScientistComputational Scientist
Required CredentialsMaster's or PhD in computational science, physics, or related fieldBachelor's or Master's in similar fields
Work EnvironmentResearch labs, R&D departments, academia, industryResearch institutions, industry, academia
Employer & Industry UsageTech companies, pharmaceuticals, aerospace, government labsUniversities, research organizations, industry
Common Search & ComparisonOften compared for experience level and responsibilitiesEntry to mid-level roles, less emphasis on leadership

Senior Computational Scientists typically have advanced degrees and more experience, leading complex projects in research and industry. Computational Scientists are often early to mid-career professionals focused on data analysis and modeling. The main difference lies in experience, project scope, and leadership responsibilities.

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What are the most commonly searched types of Computational Scientist jobs?

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Senior Computational Scientist jobs near you
Infographic showing various Senior Computational Scientist job openings in the United States as of August 2026, with employment types broken down into 1% Internship, 1% As Needed, 82% Full Time, 12% Part Time, and 4% Contract. Highlights an 82% Physical, 3% Hybrid, and 15% Remote job distribution, with an average salary of $111,343 per year, or $53.5 per hour.

Senior Computational Research Scientist

Memphis, TN • On-site

Thecentermemphis
See more jobs at Thecentermemphisexternal

$104 - $186.16/hr

Other

Posted 8 days ago

Job description

The Senior Computational Research Scientist leads, performs, and develops computational research projects under minimal supervision.

The Department of Chemical Biology and Therapeutics (CBT) is seeking a highly motivated computational chemist interested in using state‑of‑the‑art techniques in computer‑aided drug design, virtual screens, and structure‑guided drug design to discover novel small molecule modulators of targets relevant to pediatric disease. The applicant is expected to work alongside domain experts in the biology of pediatric disease, chemists, and pharmacologists, as well as the various institutional shared resources devoted to translational science, in a collaborative project team environment.

The applicant must have a strong background in computational chemistry, including molecular dynamics simulations, molecular docking, pharmacophore modeling, quantitative structure activity relationship modeling, and chemical informatics. The applicant must also be comfortable using high performance computing resources; and developing, maintaining, and mining chemical and biological databases. Proficiency in scientific computing languages, such as R and Python, and open‑source programming tools such as Knime, RDKit, and ChemProp is a plus.

Job Responsibilities
  • Lead computationally focused scientific research projects with minimal supervision from their PI. Develop new computational methods.
  • Identify, process, organize, interpret, review, and report relevant data.
  • Direct data collection.
  • Present research to colleagues within and outside the institution; draft a complex manuscript with minimal supervision, as required.
  • Regularly train and oversee the work of others in computational research and procedures.
  • Perform other duties as assigned to meet the goals and objectives of the department and institution.
  • Maintains regular and predictable attendance.
Minimum Education and/or Training
  • Bachelor's degree in Bioinformatics, Molecular Biology, Biochemistry, Computer Science, or related field.
  • Master's degree or PhD preferred.
Minimum Experience
  • Minimum Requirement: Bachelor's degree and 7+ years of relevant experience.
  • Experience Exception: Master's degree and 5+ years of relevant experience (OR) PhD with 2+ years of relevant experience.
  • Rough criteria for this position based on publication output: 1-2 first author papers IF > 10 (or equivalent contribution to other research outputs).
  • Prior experience in computational research techniques and processes.
  • Proven performance in earlier role/comparable role.
Compensation

A reasonable estimate of the current salary range is $104,000 - $186,160 per year for the role of Senior Computational Research Scientist.

Explore our exceptional benefits!

Equal Opportunity Employer

St. Jude is an Equal Opportunity Employer.

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St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

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