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Computational Toxicology Jobs (NOW HIRING)

Toxicologist

Greensboro, NC · On-site

$138K - $184K/yr

... and computational toxicology, often in collaboration with CROs. Evaluate and interpret toxicological data, including studies from scientific literature, to determine potential health impacts and ...

Toxicologist

$124K - $151K/yr

Demonstratedexpertisein the application of OECD QSAR Toolbox and other computational toxicology tools for hazard prediction, chemical categorization, read-across justification, and weight-of-evidence ...

Toxicologist

Maplewood, MN · On-site +1

$124K - $151K/yr

Demonstratedexpertisein the application of OECD QSAR Toolbox and other computational toxicology tools for hazard prediction, chemical categorization, read-across justification, and weight-of-evidence ...

Toxicologist

Austin, TX · On-site +1

$124K - $151K/yr

Demonstratedexpertisein the application of OECD QSAR Toolbox and other computational toxicology tools for hazard prediction, chemical categorization, read-across justification, and weight-of-evidence ...

Expertise in NAMs or computational toxicology * Experience with NIH scientific databases and platforms * Familiarity with in silico modeling, Adverse Outcome Pathway (AOP) frameworks, or ICCVAM/OECD ...

Computational Chemist / Cheminformatician: Help steer the development of our tool to make it ... Down the line, you'll build out a team to use our tool to generate non-toxic replacements for known ...

As an integral part of Vertex's discovery toxicology strategy, the individual will help advance the ... The ideal candidate will bring a combination of wet-laboratory and computational expertise ...

Scientific Data Analyst

Arlington, VA · On-site

$110K - $115K/yr

Expertise in NAMs or computational toxicology * Experience with NIH scientific databases and platforms * Familiarity with in silico modeling, Adverse Outcome Pathway (AOP) frameworks, or ICCVAM/OECD ...

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Computational Toxicology information

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How much do computational toxicology jobs pay per hour?

As of Sep 2, 2026, the average hourly pay for computational toxicology in the United States is $54.93, according to ZipRecruiter salary data. Most workers in this role earn between $46.88 and $73.56 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a computational toxicologist?

A strong background in toxicology, chemistry, biology, and data analytics, often with an advanced degree in a related field, is essential for a Computational Toxicologist. Expertise in computational modeling tools such as QSAR, molecular docking software, and programming languages like Python or R, as well as familiarity with regulatory databases, is typically required. Analytical thinking, problem-solving abilities, and effective communication skills set top professionals apart in this field. These skills and qualities are crucial for accurately predicting chemical safety, supporting regulatory decisions, and advancing public health initiatives.

What are some common challenges faced by computational toxicologists when integrating data from multiple sources?

Computational toxicologists often work with diverse datasets, including chemical structure information, biological assay results, and omics data. A common challenge is ensuring data compatibility and quality, as these sources may use different formats, terminologies, or measurement standards. Additionally, large datasets can present computational hurdles in terms of storage, processing, and analysis. Collaborating closely with data scientists and laboratory researchers helps address these issues and ensures that integrated datasets support robust, predictive models for toxicity assessment.
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States with the most job openings for Computational Toxicology jobs include:

Infographic showing various Computational Toxicology job openings in the United States as of August 2026, with employment types broken down into 71% Full Time, 26% Part Time, 1% Temporary, and 2% Contract. Highlights an 69% Physical, 2% Hybrid, and 29% Remote job distribution, with an average salary of $114,249 per year, or $54.9 per hour.

Senior Director, Toxicology

Revolution Medicines

Redwood City, CA • Hybrid

Full-time

Posted 10 days ago


Job description

The Opportunity:

We are seeking an experienced senior toxicologist, who combines scientific excellence with strategic leadership, for our Toxicology group within the Nonclinical Development and Clinical Pharmacology (NDCP) Department, to work in close collaboration with Research and Development colleagues on new and ongoing portfolio projects. Working within a highly collaborative, cross-functional organization, this role provides toxicology leadership from early research through all stages of clinical development, ensuring that safety assessments enable informed development decisions and global regulatory filings. The successful candidate will:

  • Lead nonclinical safety strategy for multiple drug development programs spanning both small molecules and biologics.

  • Serve as the toxicology representative on cross-functional Research and Development project teams, providing scientific guidance and influencing development strategy.

  • Design, oversee, interpret, and communicate toxicology studies that support candidate selection, IND-enabling activities, and regulatory submissions.

  • Author and review regulatory documents and ensure compliance with GLP, ICH, and global regulatory requirements.

  • Provide expert interpretation of toxicology data within the context of the current scientific approaches/best practices, project objectives, and benefit-risk assessment.

  • Lead nonclinical development sub-teams, mentor colleagues, and contribute to departmental strategy and process improvements.

  • Collaborate with investigative toxicology team to drive mechanistic studies for target-, pathway- or off-target toxicities using in vitro and in vivo studies, including emerging new approach methodologies (NAMS) such as cell- and organoid-based assays and advanced imaging analyses.

  • Drive innovation, solve complex scientific problems, and effectively manage multiple programs in a fast-paced environment.

Required Skills, Experience and Education:

  • PhD in Toxicology or a related discipline with 10+ years, or M.S. degree with 15+ years, of relevant experience in the biopharmaceutical industry; DABT certification is desirable.

  • Deep expertise in nonclinical safety assessment for small molecules and other modalities.

  • Strong understanding of toxicology study design, GLPs, global regulatory requirements, with experience interacting with global regulatory authorities.

  • Proven ability to lead cross-functional teams, influence strategy, and communicate effectively across scientific disciplines to resolve complex safety questions and support project decision-making.

  • Strong scientific background and scientific aptitude with excellent critical thinking skills.

Preferred Skills:

  • Expertise in integrating mechanistic, translational, and biomarker-based safety assessments into nonclinical development programs.
  • Familiarity with impurity risk assessment, product quality, occupational and/or environmental toxicology, or in silico/computational toxicology.

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