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$121.5K

How much do clinical site manager jobs pay per year?

As of Aug 4, 2026, the average yearly pay for clinical site manager in the United States is $80,013.00, according to ZipRecruiter salary data. Most workers in this role earn between $50,000.00 and $121,000.00 per year, depending on experience, location, and employer.

What are some common challenges clinical site managers face when overseeing multiple clinical trial sites, and how can they effectively address them?

Clinical Site Managers often juggle responsibilities across several trial sites, which can lead to challenges such as maintaining consistent protocol compliance, ensuring timely patient recruitment, and managing communication among diverse teams. To address these issues, successful Site Managers prioritize clear communication, establish regular check-ins with site staff, and utilize robust project management tools to track progress and resolve issues quickly. Building strong relationships with site personnel and proactively identifying bottlenecks also helps ensure the trials run smoothly and on schedule.

What are the key skills and qualifications needed to thrive as a clinical site manager?

To thrive as a Clinical Site Manager, you need a deep understanding of clinical research protocols, regulatory compliance, and project management, usually supported by a degree in life sciences or a related field. Familiarity with clinical trial management systems (CTMS), electronic data capture (EDC) tools, and certifications such as GCP (Good Clinical Practice) are typically required. Strong leadership, organizational skills, and effective communication set exceptional Clinical Site Managers apart. These competencies are essential for ensuring clinical trials are conducted efficiently, ethically, and in accordance with regulatory standards.

What does a clinical site manager do?

A Clinical Site Manager is responsible for overseeing the daily operations of clinical trial sites. Their main duties include managing staff, ensuring study protocols are followed, maintaining compliance with regulatory requirements, and serving as a liaison between sponsors, investigators, and site personnel. They are also tasked with monitoring patient recruitment, ensuring data quality, and resolving any issues that arise during the trial. Ultimately, they help ensure that clinical trials are conducted efficiently, safely, and in accordance with all guidelines.

What is the difference between Clinical Site Manager vs Clinical Research Coordinator?

AspectClinical Site ManagerClinical Research Coordinator
CredentialsBachelor's degree, experience in clinical trials, sometimes certificationBachelor's degree, often certification in clinical research
Work EnvironmentOversees entire site operations, manages staff, ensures complianceAssists with participant recruitment, data collection, and study procedures
Employer & IndustryResearch institutions, pharmaceutical companies, CROsResearch sites, hospitals, clinics, academic institutions

The Clinical Site Manager and Clinical Research Coordinator roles both operate within clinical research environments. The Site Manager oversees site operations and staff, while the Coordinator handles participant interactions and data collection. Both roles require related credentials and are essential for successful clinical trials, but they differ in scope and responsibilities.

More about Clinical Site Manager jobs
What cities are hiring for Clinical Site Manager jobs? Cities with the most Clinical Site Manager job openings:
What are the most commonly searched types of Clinical Site jobs? The most popular types of Clinical Site jobs are:
Who are the top companies hiring for Clinical Site Manager jobs? The top employers for Clinical Site Manager jobs are:
What states have the most Clinical Site Manager jobs? States with the most job openings for Clinical Site Manager jobs include:
What job categories do people searching Clinical Site Manager jobs look for? The top searched job categories for Clinical Site Manager jobs are:
Clinical Site Manager jobs near you
Infographic showing various Clinical Site Manager job openings in the United States as of July 2026, with employment types broken down into 94% Full Time, and 6% Contract. Highlights an 62% In-person, and 38% Remote job distribution, with an average salary of $80,013 per year, or $38.5 per hour.

Clinical Site Manager

Health Partners of Western Ohio

Toledo, OH • On-site

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Re-posted 5 days ago

Job description

School-Based Clinical Site Manager
Job Type: Full-Time, Salary Exempt
Schedule: Monday through Friday
Hours: 7:30am - 4:00pm
Will oversee multiple school-based health centers in Toledo, Ohio.
About Us
Health Partners of Western Ohio is an independent, non-profit and community-directed organization. We serve low-income areas and places without access to care. We’re led by a volunteer Board of Directors. Most of our board members are also patients. Our Mission is to eliminate gaps in health outcomes for all members of our community by providing access to quality, affordable, preventive and primary health care.
Join our Team!
Are you ready to make a lasting difference in community health? We’re seeking a dynamic leader to guide the day-to-day operations of our Community Health Center and ensure that every patient receives compassionate, high-quality care.
As Clinical Site Manager you will:
  • Provide leadership and direction across medical, dental, behavioral health, and clinical support services.
  • Partner with staff and community stakeholders to solve challenges and strengthen health center operations.
  • Drive clinical quality improvement initiatives that elevate patient outcomes and community well-being.
  • Ensure seamless coordination so our patients experience care that is effective, accessible, and centered on their needs.
This is more than a leadership role—it’s an opportunity to shape the future of integrated health services and leave a meaningful impact on the lives of individuals and families in our community.
Compensation and Benefits Offered:
  • Paid Time Off (PTO) – Accrued per pay
  • Insurance (Medical, Dental, Vision, and Life)
  • Paid Holidays – 7 paid holidays
  • 403b Retirement with up to 8% match (starts at 3% and increases with time of service at HPWO)
  • Annual Reviews and Increases
  • Mileage Reimbursement – Work related travel
  • Employee Assistance Program
  • Referral Bonus – Earn more by expanding our team
  • Training Opportunities
  • Eligible to apply for the Emerging Leaders Program after 1 year of service
QUALIFICATIONS
EDUCATION/CERTIFICATION:
Bachelor’s Degree in Health Administration, Business, Human Services or related discipline required. Master’s Degree preferred
REQUIRED KNOWLEDGE:
Successful completion of in-house training
EXPERIENCE REQUIRED:
Minimum of 5 years administrative experience in health care or human service-related organization.
SKILLS/ABILITIES:
  • Strong leadership, management, and organizational skills are required.
  • Requires experience and demonstrated abilities for working in a multi-cultural setting.
  • Ability to strongly embrace and personify the mission of Health Partners of Western Ohio.
  • Ability to collaborate and interact with a diverse group of health care professionals.
  • Ability to organize, direct, prioritizes, and delegate work appropriately.
  • Excellent analytical skills necessary for preparing financial, legal, and administrative tasks.
  • Experience with federal regulations (HIPPA, OSHA, etc.).
  • Experience in administrative functions of an ambulatory health care program.
  • Thorough knowledge of the theory and practice of organizational management, preferably in a health care and/or not-for-profit environment.
  • Effective oral and written communication necessary
  • Ability to demonstrate positive customer service skills.
ESSENTIAL FUNCTIONS AND BASIC DUTIES:
  • Participates in the support and implementation of the mission, vision and values of the Health Center, including the delivery of high quality, patient focused, integrated health care.
  • Responsible for working with employees to ensure that each employee understands their job description, the desired results associated with their work, and the resources available to achieve the results. Related to this is also the responsibility of training and developing employees to ensure they are capable for performing their duties.
  • Provides leadership for the development of policies and procedures designed to guide activities, ensuring that the site operates in a consistent and high-quality manner. Contributes to developing policies and procedures.
  • Provides consistent communication to the Administrative Team, ensuring that information, reports, and materials are provided to clearly describe activities and progress toward agreed upon objectives.
  • Participates in planning and problem solving.
  • Participates in continuing education and professional growth.
  • Maintains knowledge of, complies with, personnel, nursing, medical, dental, and clerical policies and procedures.
  • Actively works with providers and staff to develop health outreach programs consistent with Health Care Plan.
  • Motivates employees to achieve peak productivity and performance.
  • Represents the organization at various community and/or business meetings; promotes existing and new programs and/or policies.
  • Adheres to the standards and policies of the Organizational Privacy/Security and Compliance Programs, including the duty to comply with applicable laws and regulations (HIPAA, OSHA, OIG, guidelines, and other State and Federal laws). This also includes reporting to the Board of Directors, Compliance Officer, Privacy Officer, supervisor or suggestion box, any suspected unethical, fraudulent, or unlawful acts or practices.
  • Resolves problems related to staffing, utilization of facilities, equipment and supplies for the Center.
  • Evaluates performance and recommends merit increases, promotion, and disciplinary actions.
  • Analyzes and recommends changes in organizational systems, policies and procedures and ensures their implementation.
  • Actively participates in the evolution and refinement of the quality improvement process at the Center.
  • Ensures adequacy of staffing and coordination of health center(s) schedule(s) which includes all providers and supporting staff members.
  • Responsible for ensuring the operations processes for patient care are implemented. This includes staffing, data collection and interpretation of clinic flow, appointment systems, patient recall process, ancillary services and customer satisfaction.
  • Responsible for training/coaching/mentoring Supervisors with leadership training activities, management functions, and implementation of problem-solving techniques when implementing employee personnel policies and procedures.
  • Responsible to ensure program and staff compliance and safety with Health Partners policies and procedures as well as those of external regulatory bodies such as AAAHC and other professional review and standards boards, including corporate compliance.
  • Participates on a team within the organization seeking accreditation with the Accreditation Association for Ambulatory Health Care.

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