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Clinical Operations Nurse Jobs (NOW HIRING)

Whoop

Director, Clinical Operations

Boston, MA · On-site

Bachelor's degree required; advanced degree (MS, MPH, MBA, RN, PharmD, PhD, or equivalent) preferred. * 10+ years of experience in clinical operations, clinical research, medical devices, digital ...

Lark Health

Clinical Operations Lead

Mountain View, CA · On-site

$101K - $143K/yr

The Role We're looking for an RN with deep experience building digital clinical operations to help design and scale the operational backbone of our care program. This is not a traditional nursing ...

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Clinical Operations Nurse information

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$35K

$98K

$186.5K

How much do clinical operations nurse jobs pay per year?

As of Aug 10, 2026, the average yearly pay for clinical operations nurse in the United States is $98,039.00, according to ZipRecruiter salary data. Most workers in this role earn between $72,500.00 and $113,500.00 per year, depending on experience, location, and employer.

What is a clinical operations nurse?

Clinical Operations Nurses are registered nurses who oversee and coordinate the daily clinical activities within healthcare facilities, such as hospitals or clinics. They manage staff, ensure compliance with healthcare regulations, and work to improve patient care processes. Their role often involves implementing clinical protocols, supporting quality improvement initiatives, and serving as a liaison between clinical staff and administrative teams. This position is critical for maintaining efficient and effective healthcare delivery.

What is the difference between Clinical Operations Nurse vs Clinical Research Coordinator?

AspectClinical Operations NurseClinical Research Coordinator
CredentialsRN license, possibly certifications like CCRCRelevant research certifications, bachelor's degree often required
Work EnvironmentHospitals, clinics, healthcare facilitiesResearch sites, hospitals, academic institutions
Employer & IndustryHealthcare providers, hospitalsPharmaceutical companies, research organizations
Primary FocusPatient care, clinical procedures, healthcare operationsManaging clinical trials, data collection, regulatory compliance

While both roles involve clinical settings, the Clinical Operations Nurse primarily focuses on patient care and healthcare operations, whereas the Clinical Research Coordinator manages clinical trials and research activities. Both require relevant certifications and work in healthcare-related environments, but their core responsibilities differ significantly.

How does a clinical operations nurse typically collaborate with multidisciplinary teams to improve patient care processes?

Clinical Operations Nurses frequently work alongside physicians, administrative staff, case managers, and other allied health professionals to streamline patient care delivery. They help coordinate care transitions, participate in quality improvement initiatives, and facilitate communication between clinical and operational departments. This collaborative approach ensures that patient care protocols are followed efficiently while also identifying opportunities for workflow enhancements and better patient outcomes. Regular meetings and cross-functional projects are common, offering valuable exposure to various healthcare perspectives.

What are the key skills and qualifications needed to thrive as a clinical operations nurse?

A Clinical Operations Nurse needs strong clinical expertise, organizational skills, and a nursing degree with valid RN licensure. Familiarity with clinical trial management systems, quality assurance protocols, and regulatory compliance (such as GCP certification) is typically required. Outstanding communication, leadership, and problem-solving skills set top performers apart in this role. These skills ensure effective coordination of clinical workflows, adherence to protocols, and delivery of high-quality patient care in a clinical operations environment.
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What cities are hiring for Clinical Operations Nurse jobs? Cities with the most Clinical Operations Nurse job openings:
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Clinical Operations Nurse jobs near you
Infographic showing various Clinical Operations Nurse job openings in the United States as of August 2026, with employment types broken down into 86% Full Time, 11% Part Time, 1% Temporary, and 2% Contract. Highlights an 94% Physical, 2% Hybrid, and 4% Remote job distribution, with an average salary of $98,039 per year, or $47.1 per hour.

Director, Clinical Operations

Whoop

Boston, MA • On-site

Full-time

Re-posted 2 days ago

Job description

As the Director, Clinical Operations, you will lead the clinical operations function responsible for executing the studies that support WHOOP's regulated and unregulated health features, with a particular focus on Software as a Medical Device (SaMD). You will own operational strategy and study execution across the product lifecycle, from early concept and feasibility through validation, regulatory submission, launch, and post-market evidence generation.
This role requires deep expertise in clinical trial operations, decentralized clinical trials, vendor oversight, and operational execution within regulated healthcare environments. As both a strategic leader and hands-on expert, you will oversee studies conducted through CROs as well as internally executed studies, ensuring high-quality, efficient, and compliant execution across WHOOP's clinical portfolio.
You will build and mentor a high-performing Clinical Operations organization. You will strengthen WHOOP's clinical operations capabilities and ensure our study execution strategy meets the expectations of regulators, investigators, participants, and the business.
QUALIFICATIONS:
  • Own the clinical operations strategy across WHOOP's portfolio of regulated and unregulated health features, including feasibility, validation, regulatory submission, launch, and post-market evidence generation.
  • Develop and execute fit-for-purpose operational models for both internally executed studies and CRO-managed validation studies, ensuring efficient evidence generation across the product lifecycle.
  • Partner with Clinical Science and cross-functional leadership to develop study execution strategies, resource plans, vendor models, and operational timelines that balance speed, quality, cost, and regulatory requirements.
  • Lead study startup, planning, execution, monitoring, and closeout activities, ensuring timelines, budgets, enrollment targets, quality objectives, and regulatory requirements are achieved.
  • Oversee participant recruitment, enrollment, retention, study logistics, and data collection activities across both internally executed and externally managed studies.
  • Lead operational oversight of CROs, technology vendors, recruitment partners, and other external service providers, establishing scalable governance frameworks, performance metrics, and escalation pathways to ensure high-quality delivery and accountability.
  • Build and oversee capabilities for internally executed studies, including decentralized clinical trials (DCTs), feasibility studies, algorithm development studies, and product research initiatives.
  • Oversee Clinical Data Management and clinical trial technologies, ensuring high-quality, timely, and compliant data collection, management, and delivery across systems including EDC, CTMS, eConsent, ePRO, eTMF, and remote study platforms.
  • Oversee study startup and regulatory operations activities, including feasibility assessments, investigator and site selection, IRB and Ethics Committee submissions, global ethics approvals, essential document management, study activation, and Trial Master File inspection readiness.
  • Ensure studies are conducted in accordance with GCP, FDA regulations, ISO 14155, company procedures, and quality requirements, while supporting audits, inspections, and regulatory submissions.
  • Build and lead a high-performing Clinical Operations organization, including hiring, mentoring, workforce planning, and establishing scalable processes, standards, and operating models.
  • Communicate study progress, operational risks, resource needs, vendor performance, and portfolio status to executive leadership and key stakeholders.

RESPONSIBILITIES:
  • Bachelor's degree required; advanced degree (MS, MPH, MBA, RN, PharmD, PhD, or equivalent) preferred.
  • 10+ years of experience in clinical operations, clinical research, medical devices, digital health, diagnostics, pharmaceuticals, or another regulated healthcare environment.
  • 5+ years of experience leading multidisciplinary clinical operations teams, including Clinical Trial Management, Clinical Monitoring, Clinical Data Management, Study Startup, and Clinical Operations functions.
  • Demonstrated experience overseeing CRO-managed clinical studies and external vendor partnerships.
  • Experience leading internally executed clinical research programs, including decentralized clinical trials, participant-facing operations, site management, direct-to-participant research, or hybrid study models.
  • Deep expertise in clinical trial execution, study startup, participant recruitment, monitoring, enrollment, clinical data management, trial master file oversight, and study closeout activities.
  • Experience managing clinical study budgets, vendor contracts, resource forecasting, and portfolio planning.
  • Strong understanding of GCP, FDA regulations, ISO 14155, IRB/Ethics Committee processes, and medical device clinical research requirements.
  • Excellent written and verbal communication skills, with the ability to translate complex operational, clinical, and regulatory concepts for diverse audiences.

This role is based in the WHOOP office located in Boston, MA. The successful candidate must be prepared to relocate if necessary to work out of the Boston, MA office.
Interested in the role, but don't meet every qualification? We encourage you to still apply! At WHOOP, we believe there is much more to a candidate than what is written on paper, and we value character as much as experience. As we continue to build a diverse and inclusive environment, we encourage anyone who is interested in this role to apply.
WHOOP is an Equal Opportunity Employer and participates in E-verify to determine employment eligibility. It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.
The WHOOP compensation philosophy is designed to attract, motivate, and retain exceptional talent by offering competitive base salaries, meaningful equity, and consistent pay practices that reflect our mission and core values.
At WHOOP, we view total compensation as the combination of base salary, equity, and benefits, with equity serving as a key differentiator that aligns our employees with the long-term success of the company and allows every member of our corporate team to own part of WHOOP and share in the company's long-term growth and success.
The U.S. base salary range for this full-time position is $210,000-$230,000 Salary ranges are determined by role, level, and location. Within each range, individual pay is based on factors such as job-related skills, experience, performance, and relevant education or training.
In addition to the base salary, the successful candidate will also receive benefits and a generous equity package.
These ranges may be modified in the future to reflect evolving market conditions and organizational needs. While most offers will typically fall toward the starting point of the range, total compensation will depend on the candidate's specific qualifications, expertise, and alignment with the role's requirements.
Learn more about WHOOP.
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About Whoop

Sourced by ZipRecruiter

At WHOOP, we're on a mission to unlock human performance. WHOOP empowers users (Olympians, Professional Athletes, Fitness Enthusiasts, etc) to perform at a higher level through a deeper understanding of their bodies and daily lives.

Industry

Fitness and sports centers

Company size

501 - 1,000 Employees

Headquarters location

Boston, MA, US

Year founded

2012

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