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Associate Scientist Cell Line Development Jobs (NOW HIRING)

The Senior Scientist in the Cell Science Department is responsible for the development and ... Design and execute cell line development workflows, including vector design, transfection, clone ...

Associate Scientist/Scientist - Cell-Based Assay Core Facility Title: Associate Scientist/Scientist ... development, and core laboratory services for clinical trials. Cell-based Assay Core Lab The Cell ...

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Associate Scientist Cell Line Development information

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How much do associate scientist cell line development jobs pay per hour?

As of Jul 1, 2026, the average hourly pay for associate scientist cell line development in the United States is $35.92, according to ZipRecruiter salary data. Most workers in this role earn between $27.88 and $40.87 per hour, depending on experience, location, and employer.

What are some common challenges faced by Associate Scientists in Cell Line Development, and how can they be addressed?

Associate Scientists in Cell Line Development often encounter challenges such as optimizing cell growth conditions, maintaining cell line stability, and troubleshooting low productivity or contamination issues. Addressing these challenges requires strong attention to detail, effective documentation, and collaboration with cross-functional teams such as upstream process development and quality control. Regular communication with senior scientists and participation in team meetings can also help in problem-solving and ensuring project timelines are met. Staying updated on the latest techniques and technologies in cell line engineering further supports overcoming these obstacles.

What does an Associate Scientist in Cell Line Development do?

An Associate Scientist in Cell Line Development is responsible for creating and optimizing cell lines that are used in the production of biopharmaceutical products. Their work involves culturing cells, performing genetic modifications, and conducting experiments to select the best cell lines for manufacturing proteins or other biologics. They also document their findings, analyze data, and collaborate with other scientists to ensure the cell lines meet regulatory and quality standards. This role is vital in the early stages of drug development, as robust cell lines are essential for consistent and scalable production.

What is the difference between Associate Scientist Cell Line Development vs Associate Scientist Bioprocess Development?

AspectAssociate Scientist Cell Line DevelopmentAssociate Scientist Bioprocess Development
Required CredentialsBachelor's or Master's in Life Sciences, Molecular Biology, or related fieldsBachelor's or Master's in Biotechnology, Chemical Engineering, or related fields
Work EnvironmentLaboratory focused on cell line creation and characterizationLaboratory and pilot plant focused on process scale-up and manufacturing
Employer & Industry UsageBiotech and pharmaceutical companies developing cell lines for biologicsBiotech and pharma companies optimizing bioprocesses for production

Associate Scientist Cell Line Development primarily focuses on creating and characterizing cell lines for biologic production, while Associate Scientist Bioprocess Development concentrates on scaling up and optimizing manufacturing processes. Both roles require similar educational backgrounds and are essential in biologics development, but they differ in their specific focus within the biopharmaceutical pipeline.

What are the key skills and qualifications needed to thrive as an Associate Scientist in Cell Line Development, and why are they important?

To thrive as an Associate Scientist in Cell Line Development, you need a strong background in cell biology, molecular biology, and protein expression, typically supported by a relevant science degree. Familiarity with technical tools such as flow cytometry, cell culture systems, CRISPR gene editing platforms, and data analysis software is essential. Attention to detail, strong problem-solving abilities, and effective teamwork are standout soft skills in this role. These skills ensure high-quality cell line generation, reproducible results, and successful collaboration in fast-paced biopharmaceutical environments.
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Senior Scientist, Cell Science

Senior Scientist, Cell Science

SystImmune, Inc

Redmond, WA • On-site

$90K - $140K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 3 days ago


Job description

SystImmune is a leading and well-funded clinical-stage biopharmaceutical company located in Redmond, WA and Princeton, NJ. It specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi-specific, multi-specific antibodies, and antibody-drug conjugates (ADCs). SystImmune has multiple assets in various stages of clinical trials for solid tumor and hematologic indications. Alongside ongoing clinical trials. SystImmune has a robust preclinical pipeline of potential cancer therapeutics in the discover and IND-enabling stages, representing cutting-edge biologics development. We offer an opportunity for you to learn and grow while making significant contributions to the company's success.
The Senior Scientist in the Cell Science Department is responsible for the development and optimization of CHO-based processes for the production of biotherapeutics. This role requires broad expertise and the ability to contribute to both drug discovery and development projects. A strong interest in bench work and hands-on experience with mammalian cell culture is essential.
This position requires a full-time onsite presence at our Redmond, WA location.
Responsibilities:
  • Design and execute cell line development workflows, including vector design, transfection, clone screening, and selection for stable expression.
  • Perform cell culture experiments involving mammalian cells (e.g., CHO cells) under sterile, aseptic conditions.
  • Develop and optimize expression systems, including promoters, selection markers, and gene amplification strategies for high-yield production.
  • Screen and characterize clones for productivity, stability, growth characteristics, and product quality attributes using molecular and biochemical assays.
  • Collaborate with project teams and downstream process development scientists to execute protocols, experimental plans, critical production batches, and technology transfers.
  • Manage and prioritize multiple projects while supporting and coordinating with other departments to advance company objectives and develop scalable, robust culture processes.
  • Write and review Standard Operating Procedures (SOPs) and technical reports for regulatory filings.
  • Prepare process transfer documents and cGMP documentation to support the successful implementation of process technologies in clinical and commercial manufacturing operations.
  • Collaborate with R&D and the manufacturing team in China, participating in meetings and providing technical support as needed.
  • Availability to work weekend and holiday shifts, as required.
  • Perform other duties as assigned.

Qualifications:
  • Ph.D. in Cell Biology or a related field, with 5+ years of relevant experience in the pharmaceutical or biotechnology industry.
  • Strong scientific background in recombinant protein expression, cell line development, cellular metabolism, and media optimization.
  • Experience in both early- and late-stage bioreactor operations, mammalian stable cell line development, and upstream process development is preferred.
  • Demonstrated expertise in advanced technologies for cell line development, with a focus on antibody production.
  • Strong knowledge of FDA regulations and other global health authority requirements related to Investigational New Drug (IND) applications, particularly those concerning single stable clone selection and characterization.
  • Excellent written, verbal, and interpersonal communication skills.
  • Proven ability to perform effectively under pressure, meet tight deadlines, and adapt to shifting project priorities and requirements.
  • Experience with high-throughput automated workstations for clone selection is highly desirable.
Compensation and Benefits:
The expected base salary range for this position is $90,000 - $140,000 annually. Actual compensation will be based on a variety of factors, including but not limited to a candidate's qualifications, experience, and skills.
While most offers typically fall within the low to mid-point of the range, we may extend an offer toward the higher end for exceptional candidates whose background and expertise exceeds the requirements of the role.
SystImmune is a leading and well-funded biotech company with a bright future. We offer an opportunity for you to learn and grow while making significant contributions to the company's success. SystImmune offers a comprehensive benefits package including: 100% paid employee premiums for medical/dental/vision, also STD, LTD, a 401(k) plan with a 50% company match of up to 3% and a vesting schedule of only 5 years, 15 PTO days per year, sick leave, plus 11 paid holidays and MORE.
We offer an opportunity for you to learn and grow while making significant contributions to the company's success.
SystImmune is an Equal Opportunity Employer. We welcome diverse talent and encourage all qualified applicants to apply.