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Associate Scientist Cell Line Development Jobs in Maryland

Hunterian Medicine

Scientist (Cell Culture)

Baltimore, MD · On-site

  • Medical

  • Retirement

  • PTO

We are seeking a highly motivated individual to join our R&D team to develop novel therapeutics using CRISPR and gene therapies. We are looking for a Cell Culture Scientist who will be responsible ...

Merck Group

Associate Scientist 2 - 2nd Shift

Rockville, MD · On-site

$27 - $44/hr

  • Medical

  • Retirement

  • PTO

... development through commercial application of new and innovative service offerings within the ... PCR, Cell culture and cell manipulation experience. * Basic skills in applicable computer programs.

Guidehouse

Associate Scientist

Gaithersburg, MD · On-site

$65K - $108K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

We are seeking an Associate Scientist to support formulation development, stability studies, analytical testing, and documentation for vaccine and biotherapeutic programs at the National Institute of ...

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All JobsAssociate Scientist Cell Line Development JobsAssociate Scientist Cell Line Development Jobs in Maryland

Associate Scientist Cell Line Development information

What are some common challenges faced by associate scientists in cell line development, and how can they be addressed?

Associate Scientists in Cell Line Development often encounter challenges such as optimizing cell growth conditions, maintaining cell line stability, and troubleshooting low productivity or contamination issues. Addressing these challenges requires strong attention to detail, effective documentation, and collaboration with cross-functional teams such as upstream process development and quality control. Regular communication with senior scientists and participation in team meetings can also help in problem-solving and ensuring project timelines are met. Staying updated on the latest techniques and technologies in cell line engineering further supports overcoming these obstacles.

What does an associate scientist in cell line development do?

An Associate Scientist in Cell Line Development is responsible for creating and optimizing cell lines that are used in the production of biopharmaceutical products. Their work involves culturing cells, performing genetic modifications, and conducting experiments to select the best cell lines for manufacturing proteins or other biologics. They also document their findings, analyze data, and collaborate with other scientists to ensure the cell lines meet regulatory and quality standards. This role is vital in the early stages of drug development, as robust cell lines are essential for consistent and scalable production.

What is the difference between Associate Scientist Cell Line Development vs Associate Scientist Bioprocess Development?

AspectAssociate Scientist Cell Line DevelopmentAssociate Scientist Bioprocess Development
Required CredentialsBachelor's or Master's in Life Sciences, Molecular Biology, or related fieldsBachelor's or Master's in Biotechnology, Chemical Engineering, or related fields
Work EnvironmentLaboratory focused on cell line creation and characterizationLaboratory and pilot plant focused on process scale-up and manufacturing
Employer & Industry UsageBiotech and pharmaceutical companies developing cell lines for biologicsBiotech and pharma companies optimizing bioprocesses for production

Associate Scientist Cell Line Development primarily focuses on creating and characterizing cell lines for biologic production, while Associate Scientist Bioprocess Development concentrates on scaling up and optimizing manufacturing processes. Both roles require similar educational backgrounds and are essential in biologics development, but they differ in their specific focus within the biopharmaceutical pipeline.

What are the key skills and qualifications needed to thrive as an associate scientist in cell line development?

To thrive as an Associate Scientist in Cell Line Development, you need a strong background in cell biology, molecular biology, and protein expression, typically supported by a relevant science degree. Familiarity with technical tools such as flow cytometry, cell culture systems, CRISPR gene editing platforms, and data analysis software is essential. Attention to detail, strong problem-solving abilities, and effective teamwork are standout soft skills in this role. These skills ensure high-quality cell line generation, reproducible results, and successful collaboration in fast-paced biopharmaceutical environments.

What cities in Maryland are hiring for Associate Scientist Cell Line Development jobs?

Cities in Maryland with the most Associate Scientist Cell Line Development job openings:

Associate Scientist Cell Line Development jobs near you

Senior Scientist, Bioproduction and Bioprocessing

Join Our Team

Rockville, MD • On-site

$93K - $127K/yr

Full-time

Medical, Dental, Vision, Life

Posted 6 days ago

Job description

Description:

The Senior Scientist, Bioproduction & Bioprocessing is responsible for leading the development, optimization, and execution of mammalian cell-based protein production workflows to support organizational research, development, and manufacturing needs. This role provides subject-matter expertise in cell line development, transient expression, and upstream bioprocessing, and ensures high-quality delivery of materials through collaboration with cross-functional teams. The Senior Scientist contributes to scientific innovation, process improvement, and customer support activities.

  • Lead and execute workflows for stable pool and stable cell line generation, including transfection, clone screening, productivity assessment, and documentation.
  • Perform stable pool and transient experiments using CHOZN, CHOK1-sv, CHOK, HEK293, and other protein production-relevant cell lines.
  • Develop, optimize, and scale transient protein expression processes for antibodies and recombinant proteins.
  • Conduct upstream protein expression studies, including small-scale evaluations and preparation for scale-up.
  • Design, perform, and troubleshoot laboratory experiments in accordance with established protocols, quality standards, and regulatory expectations.
  • Analyze experimental data, prepare technical summaries, and present results to internal and external stakeholders.
  • Collaborate with downstream purification, analytical development, and project management teams to ensure alignment and timely delivery of materials.
  • Provide scientific support to customer-facing teams, including remote and onsite troubleshooting with Field Application Scientists.
  • Identify opportunities to enhance bioproduction workflows, including media/feed optimization, vector improvements, and process parameter refinement.
  • Evaluate and implement new technologies, automation tools, and high-throughput approaches to increase efficiency and scalability.
  • Lead exploratory studies to assess emerging bioprocessing methods and integrate validated improvements into standard workflows.
  • Contribute to internal innovation initiatives, including development of new production strategies, platform enhancements, and scientific capability expansion.
  • Provide technical insight to support long-term bioproduction strategy and organizational growth.
  • Maintain accurate, complete, and compliant laboratory records.
  • Ensure adherence to organizational, regulatory, and safety standards.
Requirements:
  • PhD in biological sciences or related field with 10+ years of relevant industry experience (or Master’s degree with 13+ years of experience) in bioproduction, bioprocessing, or cell line development
  • Demonstrated expertise in stable cell line development and clone selection.
  • Extensive hands-on experience with transient expression of antibodies or recombinant proteins.
  • Strong foundation in mammalian cell culture and upstream protein expression.
  • Experience with high-throughput screening, automation, or advanced analytical tools.
  • Background in cell engineering, vector design, media/feed optimization, or bioprocess development.
  • Prior experience in structured, milestone-driven industry or core laboratory environments.
  • Good communication skills and ability to work collaboratively with internal team members and customers
  • Ability to travel up to 20%


MaxCyte offers a base salary, annual bonus, and equity. MaxCyte also offers a comprehensive benefits package including health, dental, vision, life, and disability insurance and generous time off.


MaxCyte is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, sex, sexual orientation, gender identity, religion, national origin, disability, veteran status, age, marital status, pregnancy, genetic information, or other legally protected status

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