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Scientist Molecular Cell Line Development Jobs (NOW HIRING)

RXinsider LTD.

NY · On-site

Execute mammalian cell line development workflows, including transfection, stable pool generation ... Master's degree in biology, Cell Biology, Molecular Biology, Biochemical Engineering, Biochemistry ...

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Alloy Therapeutics

Head of Cell Line Development

Waltham, MA · On-site

$150K - $215K/yr

Scientific direction and execution of cell line technology development projects. * Innovate: Ensure ... D. in Cell Biology, Molecular Biology, Biochemical Engineering, or a related field * 10+ years of ...

Alloy Therapeutics

Head of Cell Line Development

Waltham, MA · On-site

$150K - $215K/yr

Scientific direction and execution of cell line technology development projects. * Innovate: Ensure ... D. in Cell Biology, Molecular Biology, Biochemical Engineering, or a related field * 10+ years of ...

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How much do scientist molecular cell line development jobs pay per hour?

As of Sep 15, 2026, the average hourly pay for scientist molecular cell line development in the United States is $38.66, according to ZipRecruiter salary data. Most workers in this role earn between $28.37 and $46.15 per hour, depending on experience, location, and employer.

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Infographic showing various Scientist Molecular Cell Line Development job openings in the United States as of August 2026, with employment types broken down into 1% As Needed, 83% Full Time, 14% Part Time, and 2% Contract. Highlights an 86% Physical, 3% Hybrid, and 11% Remote job distribution, with an average salary of $80,420 per year, or $38.7 per hour.

Senior Scientist, Cell Line Development

Gaithersburg, MD • On-site

AstraZeneca
Pharmaceutical Product Wholesalers • 10K+ employees
Learn more about AstraZenecaexternal

$112K - $168K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 12 days ago

AstraZeneca rating

8.4

Company rating: 8.4 out of 10

Based on 45 frontline employees who took The Breakroom Quiz

Job description

Your work will center on independently accomplishing single-cell isolation, small-scale viral packaging, high-throughput screening, and evaluating clone productivity and product quality to deliver stable and top-performing clones supporting AstraZeneca's emerging Cell Therapy portfolio. This position is based in Gaithersburg, MD.
Key Responsibilities:
  • Cell Line Development & Viral Packaging: Perform mammalian CLD activities, including single-cell and mini-pool generation, small-scale viral vector packaging and high throughput titration, and clone selection to achieve robust viral productivity for upstream processes.
  • High-Throughput Screening & Analytics Interface: Establish efficient, scalable workflows for rapid cell characterization and clone evaluation, and high-throughput titer screening; partner with analytical and process development teams to link clone selection choices to critical quality attributes using molecular/cell analytics (e.g., flow cytometry, qPCR/ddPCR, ELISA, titering assays).
  • Cell line engineering: lead and implement cell line engineering to improve cell line performance, including LVV packaging efficiency, vector quality, genetic stability and overall robustness
  • Data Analysis & Collaboration: Analyze and interpret complex datasets, maintain accurate experimental documentation, and collaborate with upstream Process Development and Analytical teams to support smooth process handoffs.

Qualifications:
  • Education: PhD degree or Master's degree (or equivalent to 3-4 years of experience) in Cell Biology, Molecular Biology, Bioengineering, Virology, or a related scientific field.

Core Technical Expertise:
  • Extensive, hands-on experience in mammalian CLD, viral vector packaging, and clone screening, with a strong emphasis on cultivating and optimizing HEK293 based host cells in suspension culture for high-yield Lentiviral vector production.
  • Proficiency in single-cell isolation using cell sorter, advanced imaging systems, and clone characterization via flow cytometry.
  • Experience with high-throughput titration assays and utilizing, maintaining, and troubleshooting automated liquid handling and high-throughput screening platforms.
  • Experience with stable genetic modification of mammalian cells using approaches such as CRISPR/cas9

Desirable Experience:
  • Experience in monoclonality validation and expanding stable master cell lines.
  • Hands-on experience in virus/vector engineering for host cell line optimization or vector performance improvement.
  • Background in viral vector biology, cell and gene therapy within the pharmaceutical industry, supporting vector design/engineering for maximized titers, quality and overall manufacturability.
  • Viral vector stable producer cell line development

Core Competencies: Effective interpersonal skills, meticulous attention to detail, and independent troubleshooting capabilities and in a fast-paced laboratory environment.
The annual base pay for this position ranges from $
112,304.00 - 168,456.00
The annual base pay for this position ranges from $112,304.00 - $168,456.00 . Our positions offer eligibility for various incentives-an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.
Our positions offer eligibility for various incentives-an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.
Date Posted
03-Sep-2026
Closing Date
17-Sep-2026
Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

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About AstraZeneca

Sourced by ZipRecruiter

AstraZeneca is a global, science-led, patient-focused biopharmaceutical company that focuses on the discovery, development and commercialization of prescription medicines for some of the world's most serious diseases. But we're more than one of the world's leading pharmaceutical companies. A place built on courage, curiosity and collaboration - we make bold decisions driven by patient outcomes. Empowered to lead at every level, free to ask questions and take smart risks that write the next chapter for our pipeline and Oncology team. Make a meaningful impact that brings real benefits to society. By applying your knowledge of data, you will help to redefine our industry and ultimately save lives. Work with experts who share a common goal: to accelerate the potential of medicines and the science of tomorrow.

Industry

Pharmaceutical product wholesalers and pharmaceutical and medicine manufacturing

Company size

10,000+ Employees

Headquarters location

Cambridge, Cambridgeshire, GB

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