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Associate Scientist Cell Line Development Jobs in Tennessee

The Associate Research Scientist is responsible for assisting the Research Scientist and the Formulation Sciences department in the development of new OTC Skin Care/Cosmetic/Personal Care products ...

The Associate Research Scientist is responsible for assisting the Research Scientist and the Formulation Sciences department in the development of new OTC Skin Care/Cosmetic/Personal Care products ...

Senior Scientist

Knoxville, TN · Hybrid

$87K - $119K/yr

Our research and development is currently supported and funded by the U.S. Army, U.S. Department of ... Implementing and managing tests to characterize components, processes and fuel cell performances ...

Senior Scientist

Knoxville, TN · On-site

$87K - $119K/yr

Our research and development is currently supported and funded by the U.S. Army, U.S. Department of ... Implementing and managing tests to characterize components, processes and fuel cell performances ...

... cell-cell interactions. * Elucidate immune mechanisms that support novel immune-modulating ... Supervisory responsibilities include mentorship and development of scientists and research staff.

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Associate Scientist Cell Line Development information

What are some common challenges faced by Associate Scientists in Cell Line Development, and how can they be addressed?

Associate Scientists in Cell Line Development often encounter challenges such as optimizing cell growth conditions, maintaining cell line stability, and troubleshooting low productivity or contamination issues. Addressing these challenges requires strong attention to detail, effective documentation, and collaboration with cross-functional teams such as upstream process development and quality control. Regular communication with senior scientists and participation in team meetings can also help in problem-solving and ensuring project timelines are met. Staying updated on the latest techniques and technologies in cell line engineering further supports overcoming these obstacles.

What does an Associate Scientist in Cell Line Development do?

An Associate Scientist in Cell Line Development is responsible for creating and optimizing cell lines that are used in the production of biopharmaceutical products. Their work involves culturing cells, performing genetic modifications, and conducting experiments to select the best cell lines for manufacturing proteins or other biologics. They also document their findings, analyze data, and collaborate with other scientists to ensure the cell lines meet regulatory and quality standards. This role is vital in the early stages of drug development, as robust cell lines are essential for consistent and scalable production.

What is the difference between Associate Scientist Cell Line Development vs Associate Scientist Bioprocess Development?

AspectAssociate Scientist Cell Line DevelopmentAssociate Scientist Bioprocess Development
Required CredentialsBachelor's or Master's in Life Sciences, Molecular Biology, or related fieldsBachelor's or Master's in Biotechnology, Chemical Engineering, or related fields
Work EnvironmentLaboratory focused on cell line creation and characterizationLaboratory and pilot plant focused on process scale-up and manufacturing
Employer & Industry UsageBiotech and pharmaceutical companies developing cell lines for biologicsBiotech and pharma companies optimizing bioprocesses for production

Associate Scientist Cell Line Development primarily focuses on creating and characterizing cell lines for biologic production, while Associate Scientist Bioprocess Development concentrates on scaling up and optimizing manufacturing processes. Both roles require similar educational backgrounds and are essential in biologics development, but they differ in their specific focus within the biopharmaceutical pipeline.

What are the key skills and qualifications needed to thrive as an Associate Scientist in Cell Line Development, and why are they important?

To thrive as an Associate Scientist in Cell Line Development, you need a strong background in cell biology, molecular biology, and protein expression, typically supported by a relevant science degree. Familiarity with technical tools such as flow cytometry, cell culture systems, CRISPR gene editing platforms, and data analysis software is essential. Attention to detail, strong problem-solving abilities, and effective teamwork are standout soft skills in this role. These skills ensure high-quality cell line generation, reproducible results, and successful collaboration in fast-paced biopharmaceutical environments.
What are popular job titles related to Associate Scientist Cell Line Development jobs in Tennessee? For Associate Scientist Cell Line Development jobs in Tennessee, the most frequently searched job titles are:
What job categories do people searching Associate Scientist Cell Line Development jobs in Tennessee look for? The top searched job categories for Associate Scientist Cell Line Development jobs in Tennessee are:
What cities in Tennessee are hiring for Associate Scientist Cell Line Development jobs? Cities in Tennessee with the most Associate Scientist Cell Line Development job openings:
Associate Scientist - Epigenetic Basis of Pediatric Brain Disease - Jamy Peng Lab

Associate Scientist - Epigenetic Basis of Pediatric Brain Disease - Jamy Peng Lab

St. Jude Children's Research Hospital

Memphis, TN • On-site

$65K - $114K/yr

Full-time

Posted 25 days ago


St. Jude Children's Research Hospital rating

8.4

Company rating: 8.4 out of 10

Based on 9 frontline employees who took The Breakroom Quiz

61st of 994 rated hospitals


Job description

The Associate Scientist performs a variety of moderately complex research tasks determined by the field and scope of the particular research project/study. Also, performs tasks related to the research project independently, but within broad guidelines and subject to periodic review by supervisor or other research staff.
The lab of Jamy Peng in the Department of Developmental Neurobiology at St. Jude Children's Research Hospital is seeking an Associate Scientist to investigate how genomic DNA organization and gene regulation within stem cells influence their function and identity, explore chromatin structure, histone modifications, and their impact on gene expression in stem cells, and contribute to uncovering the molecular basis of pediatric cancer and normal development.
The ideal candidate will have the following:
  • Strong background in developmental biology, molecular biology, stem cell biology, or closely related fields.
  • Deep understanding of epigenetics, including: chromatin structure and organization; histone modifications; epigenetic regulation of gene expression; protein-RNA interactions in stem cells
  • Hands-on experience with techniques commonly used to interrogate epigenetic mechanisms (e.g., ChIP-seq, ATAC-seq, RNA-seq, CRISPR-based perturbation, imaging assays, stem cell assays).
  • Strong competence in designing, executing, and troubleshooting independent experiments using existing or newly developed protocols.

Job Responsibilities:
  • Independently perform experiments using existing, modified, or newly developed techniques/ protocols.
  • Set up protocols using new or modified laboratory techniques and troubleshoot experiments independently.
  • Identify experimental data pertinent to the analysis problem; process, organize, and summarize data; report results.
  • Assist in the drafting and editing of manuscripts, posters, SOPs, and policies.
  • Maintain up-to-date knowledge of the field and related techniques.
  • Provide ongoing support for monitoring, maintenance, ordering, and purchasing of equipment and supplies as needed.
  • Perform calibration of instruments and equipment as necessary.
  • Provide guidance and training to less-experienced team members and may also train others outside lab in relevant techniques.
  • Perform other duties as assigned to meet the goals and objectives of the department and the institution.
  • Maintain regular and predictable attendance.

Minimum Education and/or Training:
  • Bachelor's degree in a relevant scientific area

Minimum Experience:
  • 7 + years of research experience is required
  • 5 + years of research experience is required with a Master's degree
  • 2 + years of research experience is required with a PHD
  • Experience leading and supporting research experiments preferred
  • Some experience leading lab and scientific project coordination, maintenance, and other research support activities preferred
  • Experience in guiding and training other laboratory personnel preferred
  • Proven performance in earlier role/comparable role

Please direct your questions and application package, including a cover letter, current CV, and 3 letters of reference to: jamy.peng@stjude.org.
Compensation
In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $65,520 - $114,400 per year for the role of Associate Scientist - Epigenetic Basis of Pediatric Brain Disease - Jamy Peng Lab.
Explore our exceptional benefits!
St. Jude is an Equal Opportunity Employer
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St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.