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Associate Scientist Cell Line Development Jobs in Tennessee

St. Jude Children's Research Hospital

$86K - $154K/yr

Scientist / Associate Scientist - Preclinical Design & Development (PDD) Core Location Memphis, TN ... Proficiency in mammalian cell culture, including complex or patient‑derived cellular models.

New

Vanderbilt University

Staff Scientist

Nashville, TN · On-site

Reporting directly to the Associate Director of VGER, the Staff Scientist serves as an integral ... cell line generation is strongly preferred. * Knowledge of developmental biology, stem cell biology ...

Eastman

Associate Applications Scientist

Kingsport, TN · On-site

Description Eastman Chemical Company is seeking an experienced Applications Development / Research Scientist to advance the Aventa™ biodegradable polymers product family through product development ...

Eastman

Associate Applications Scientist

Kingsport, TN · On-site

Description Eastman Chemical Company is seeking an experienced Applications Development / Research Scientist to advance the Aventa™ biodegradable polymers product family through product development ...

St. Jude Children's Research Hospital

Postdoctoral Research Associate - Developmental Neurobiology - Solecki Lab Location Memphis, TN ... of biophysicists, optics experts, data scientists, cell-biologists and developmental ...

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All JobsAssociate Scientist Cell Line Development JobsAssociate Scientist Cell Line Development Jobs in Tennessee

Associate Scientist Cell Line Development information

What does an associate scientist in cell line development do?

An Associate Scientist in Cell Line Development is responsible for creating and optimizing cell lines that are used in the production of biopharmaceutical products. Their work involves culturing cells, performing genetic modifications, and conducting experiments to select the best cell lines for manufacturing proteins or other biologics. They also document their findings, analyze data, and collaborate with other scientists to ensure the cell lines meet regulatory and quality standards. This role is vital in the early stages of drug development, as robust cell lines are essential for consistent and scalable production.

What are the key skills and qualifications needed to thrive as an associate scientist in cell line development?

To thrive as an Associate Scientist in Cell Line Development, you need a strong background in cell biology, molecular biology, and protein expression, typically supported by a relevant science degree. Familiarity with technical tools such as flow cytometry, cell culture systems, CRISPR gene editing platforms, and data analysis software is essential. Attention to detail, strong problem-solving abilities, and effective teamwork are standout soft skills in this role. These skills ensure high-quality cell line generation, reproducible results, and successful collaboration in fast-paced biopharmaceutical environments.

What are some common challenges faced by associate scientists in cell line development, and how can they be addressed?

Associate Scientists in Cell Line Development often encounter challenges such as optimizing cell growth conditions, maintaining cell line stability, and troubleshooting low productivity or contamination issues. Addressing these challenges requires strong attention to detail, effective documentation, and collaboration with cross-functional teams such as upstream process development and quality control. Regular communication with senior scientists and participation in team meetings can also help in problem-solving and ensuring project timelines are met. Staying updated on the latest techniques and technologies in cell line engineering further supports overcoming these obstacles.

What is the difference between Associate Scientist Cell Line Development vs Associate Scientist Bioprocess Development?

AspectAssociate Scientist Cell Line DevelopmentAssociate Scientist Bioprocess Development
Required CredentialsBachelor's or Master's in Life Sciences, Molecular Biology, or related fieldsBachelor's or Master's in Biotechnology, Chemical Engineering, or related fields
Work EnvironmentLaboratory focused on cell line creation and characterizationLaboratory and pilot plant focused on process scale-up and manufacturing
Employer & Industry UsageBiotech and pharmaceutical companies developing cell lines for biologicsBiotech and pharma companies optimizing bioprocesses for production

Associate Scientist Cell Line Development primarily focuses on creating and characterizing cell lines for biologic production, while Associate Scientist Bioprocess Development concentrates on scaling up and optimizing manufacturing processes. Both roles require similar educational backgrounds and are essential in biologics development, but they differ in their specific focus within the biopharmaceutical pipeline.

What cities in Tennessee are hiring for Associate Scientist Cell Line Development jobs?

Cities in Tennessee with the most Associate Scientist Cell Line Development job openings:

Associate Scientist Cell Line Development jobs near you

Associate Scientist - Single Cell Genomics Core / Neurocytometry Core

Memphis, TN • On-site

St. Jude Children's Research Hospital
Health Care and Social Assistance • 1 - 5K employees
Learn more about St. Jude Children's Research Hospitalexternal

Full-time

Posted 11 days ago

St. Jude Children's Research Hospital rating

8.8

Company rating: 8.8 out of 10

Based on 13 frontline employees who took The Breakroom Quiz

Job description

The Associate Scientist position will have responsibilities in both the Single Cell Genomics Core and the Neurocytometry Core within the Department of Developmental Neurobiology at St. Jude Children's Research Hospital. The candidate will independently perform tasks related to both cores - supporting single-cell sample processing, sequencing workflows, flow cytometry, instrument operation, user training, and multicolor panel design.
The Single Cell Genomics and Neurocytometry Cores provide investigators studying the developing and diseased nervous system with access to single-cell genomic and flow cytometric technologies optimized for neural tissue.
The Associate Scientist will support both cores, helping researchers isolate cells or nuclei and generate high-quality single-cell and flow cytometry datasets in support of developmental neurobiology, cancer, and translational research programs across the institution. This position combines hands-on operation, troubleshooting, and quality control of single-cell sequencing platforms (e.g., 10x Genomics Chromium) with instrument setup, calibration, and multicolor panel design on flow cytometers and cell sorters. The successful candidate will work closely with core leadership and investigators across the Department of Developmental Neurobiology to optimize tissue dissociation protocols, complete library preparations, develop and run new high-parameter cytometry panels, and train users on both platforms.
The ideal candidate will have the following:
  • Strong background in developmental biology, molecular biology, neuroscience, stem cell biology, or a closely related field.
  • Strong competence in designing, executing, and troubleshooting independent experiments using existing or newly developed protocols.
  • Experience with single-cell genomic workflows (e.g., 10x Genomics Chromium, single-cell RNA-seq library preparation) is preferred.
  • Familiarity with neural tissue dissociation and analysis of neuronal, glial, and other cell populations in the brain and spinal cord.
  • Hands-on experience with flow cytometry and cell sorting instrumentation, including instrument setup, calibration, and troubleshooting.
  • Proficient knowledge of molecular biology and experience designing and analyzing multicolor/high parameter flow cytometry panels.
  • Demonstrated experience with flow data analysis platforms (e.g., FlowJo, DIVA, OMIQ) and Microsoft Office products.
  • Demonstrated success in training and supporting other technicians, students, and investigators.
  • Strong organizational and communication skills
  • Positive attitude with strong interpersonal skills and a collaborative, team-oriented approach. Interest in learning new technologies

Job Responsibilities:
  • Independently perform experiments using existing, modified, or newly developed techniques/protocols.
  • Accurately record experimental procedures and data
  • Prepare and report results/ data leading to posters, presentations, or publications
  • Set up protocols using new or modified laboratory techniques and troubleshoot experiments independently.
  • Identify experimental data pertinent to the analysis problem; process, organize, and summarize data; report results.
  • Independently perform single-cell sample processing, including neural tissue/cell dissociation, viability assessment, and loading onto single-cell sequencing platforms (e.g., 10x Genomics Chromium).
  • Coordinate sample intake, quality control, and sequencing run scheduling for the Single Cell Genomics Core and communicate results and troubleshooting steps to investigators.
  • Establish, modify, and implement Standard Operating Procedures (SOPs) for routine maintenance and performance evaluation of flow cytometers and associated instrumentation.
  • Independently perform instrument setup, sample acquisition, calibration, alignment, troubleshooting; oversee instrument repair and service coordination.
  • Train technicians, students, and investigators on cytometry concepts, including instrument startup/shutdown, routine maintenance, sample acquisition, and basic data analysis.
  • Collaborate with investigators to develop, evaluate, and optimize multicolor flow cytometry assays, including high-parameter panels.
  • Perform regular cell sorting services and support users in developing technically sound, biologically relevant cytometry-based approaches.
  • Provide ongoing support for monitoring, maintenance, ordering, and purchasing of equipment and supplies as needed.
  • Perform other duties as assigned to meet the goals and objectives of the department and the institution.
  • Maintain regular and predictable attendance.

Minimum Education and/or Training:
  • Bachelor's degree in a relevant scientific area

Minimum Experience:
  • 7 + years of research experience is required
  • 5 + years of research experience is required with a Master's degree
  • 2 + years of research experience is required with a PHD
  • Experience leading and supporting research experiments preferred
  • Some experience leading lab and scientific project coordination, maintenance, and other research support activities preferred
  • Experience in guiding and training other laboratory personnel preferred
  • Proven performance in earlier role/comparable role

Compensation
In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $65,520 - $114,400 per year for the role of Associate Scientist - Single Cell Genomics Core / Neurocytometry Core.
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We are committed to a human-centered hiring experience. Technology may support portions of our process, but recruiting decisions involve human review and engagement. Learn more about our approach to AI.
St. Jude is an Equal Opportunity Employer
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St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

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