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Associate Scientist Cell Line Development Jobs in Tennessee

U.S. Department of Defense (DOD)

$61K/yr

... or teaching, test development, or medical research program experience that provided an ... Related fields include physiology, anatomy, molecular biology, cell biology, embryology, pathology ...

Integrated Resources INC

Scientist II

Memphis, TN

... development. Responsibilities: * Responsible for the design and conduct of experiments as defined ... Experience with cell culture techniques imperative * Hands-on experience with flow cytometry and ...

Cracker Barrel

Assistant Buyer

Lebanon, TN · On-site

$19.25 - $25.50/hr

Initiates, tracks, receives, and organizes product samples for review, line development, and model ... Associate Buyer, Sr. Buyer, Director of Merchandise, and VP/GMM, through meeting preparation ...

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Associate Scientist Cell Line Development information

What are some common challenges faced by Associate Scientists in Cell Line Development, and how can they be addressed?

Associate Scientists in Cell Line Development often encounter challenges such as optimizing cell growth conditions, maintaining cell line stability, and troubleshooting low productivity or contamination issues. Addressing these challenges requires strong attention to detail, effective documentation, and collaboration with cross-functional teams such as upstream process development and quality control. Regular communication with senior scientists and participation in team meetings can also help in problem-solving and ensuring project timelines are met. Staying updated on the latest techniques and technologies in cell line engineering further supports overcoming these obstacles.

What does an Associate Scientist in Cell Line Development do?

An Associate Scientist in Cell Line Development is responsible for creating and optimizing cell lines that are used in the production of biopharmaceutical products. Their work involves culturing cells, performing genetic modifications, and conducting experiments to select the best cell lines for manufacturing proteins or other biologics. They also document their findings, analyze data, and collaborate with other scientists to ensure the cell lines meet regulatory and quality standards. This role is vital in the early stages of drug development, as robust cell lines are essential for consistent and scalable production.

What is the difference between Associate Scientist Cell Line Development vs Associate Scientist Bioprocess Development?

AspectAssociate Scientist Cell Line DevelopmentAssociate Scientist Bioprocess Development
Required CredentialsBachelor's or Master's in Life Sciences, Molecular Biology, or related fieldsBachelor's or Master's in Biotechnology, Chemical Engineering, or related fields
Work EnvironmentLaboratory focused on cell line creation and characterizationLaboratory and pilot plant focused on process scale-up and manufacturing
Employer & Industry UsageBiotech and pharmaceutical companies developing cell lines for biologicsBiotech and pharma companies optimizing bioprocesses for production

Associate Scientist Cell Line Development primarily focuses on creating and characterizing cell lines for biologic production, while Associate Scientist Bioprocess Development concentrates on scaling up and optimizing manufacturing processes. Both roles require similar educational backgrounds and are essential in biologics development, but they differ in their specific focus within the biopharmaceutical pipeline.

What are the key skills and qualifications needed to thrive as an Associate Scientist in Cell Line Development, and why are they important?

To thrive as an Associate Scientist in Cell Line Development, you need a strong background in cell biology, molecular biology, and protein expression, typically supported by a relevant science degree. Familiarity with technical tools such as flow cytometry, cell culture systems, CRISPR gene editing platforms, and data analysis software is essential. Attention to detail, strong problem-solving abilities, and effective teamwork are standout soft skills in this role. These skills ensure high-quality cell line generation, reproducible results, and successful collaboration in fast-paced biopharmaceutical environments.
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What job categories do people searching Associate Scientist Cell Line Development jobs in Tennessee look for? The top searched job categories for Associate Scientist Cell Line Development jobs in Tennessee are:
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Associate Scientist Cell Line Development jobs near you
Bioinformatics Research Scientist

Bioinformatics Research Scientist

St. Jude Children's Research Hospital

Memphis, TN • On-site

Full-time

Posted 5 days ago

St. Jude Children's Research Hospital rating

8.6

Company rating: 8.6 out of 10

Based on 12 frontline employees who took The Breakroom Quiz

37th of 1,023 rated hospitals

Job description

The Bioinformatics Research Scientist is responsible for designing, developing, improving, modifying, and operating data analysis pipelines. Manages projects and coordinates other efforts related to analysis and infrastructure as directed.
The Escoubas Laboratory, within the Center of Excellence in Neuro-Oncology Sciences (CENOS) at St. Jude Children's Research Hospital, is seeking a highly motivated Bioinformatics Research Scientist to join our growing research team. CENOS fosters a collaborative and innovative scientific environment dedicated to advancing discoveries that improve outcomes for children with brain tumors.
The Escoubas Lab investigates bidirectional communication between neurons and microglia through nucleic acid sensing pathways, with implications for neurodevelopment, neurological disease, and pediatric brain tumors. This position is ideal for an individual with a strong background in bioinformatics, computational biology, or systems biology who is passionate about applying advanced computational approaches to complex biological questions.
The successful candidate will partner closely with the Principal Investigator and laboratory members to develop and implement robust analytical workflows for single-cell and spatial omics datasets, neuronal activity analyses, and human genetic studies. This role offers an exciting opportunity to contribute to high-impact research at the intersection of neuroscience, immunology, and pediatric cancer biology.
The Bioinformatics Research Scientist will be expected to:
  • Develop, maintain, and optimize analytical pipelines for single-cell RNA sequencing (scRNA-seq), bulk RNA sequencing, spatial transcriptomics, spatial proteomics, and neuronal activity datasets, including multi-electrode array (MEA) data.
  • Perform genome-wide association study (GWAS) enrichment analyses and integrate multi-omic datasets to investigate mechanisms relevant to neurodevelopment, neurological disorders, and pediatric brain tumors.
  • Collaborate closely with laboratory scientists to design analyses, interpret results, and generate publication-quality data visualizations.
  • Develop reproducible computational workflows and implement best practices for data processing, quality control, statistical analysis, and data management.
  • Assist in onboarding and mentoring new laboratory members in computational tools, bioinformatics workflows, and data analysis methodologies.
  • Coordinate with St. Jude core facilities, including genomics, proteomics, and imaging platforms, to facilitate sample submissions, data acquisition, and data management.
  • Contribute to scientific manuscripts, grant applications, presentations, and other dissemination of research findings.
  • Work independently while fostering a collaborative and inclusive research environment with laboratory members and institutional colleagues.
  • Maintain accurate documentation of computational methods, analyses, and results to ensure reproducibility and transparency.
  • Maintain regular and reliable attendance.
  • Perform other duties as assigned in support of the scientific goals of the laboratory and institution.

Preferred Qualifications
  • PhD or equivalent research experience in Bioinformatics, Computational Biology, Neuroscience, or a related field.
  • Experience analyzing high-dimensional genomic and transcriptomic datasets, including single-cell and spatial omics data.
  • Proficiency in R, Python, Linux/Unix environments, and workflow development.
  • Familiarity with neuronal activity analyses, network biology, machine learning approaches, and multi-omic data integration is highly desirable.
  • Strong communication skills and a demonstrated ability to work effectively within multidisciplinary research teams.
  • Familiarity with GWAS methodology and enrichment analysis tools
  • Experience with research coordination in an academic setting
  • Excellent organizational and communication skills
  • Ability to work independently and collaboratively in a fast-paced research environment.

Minimum Education and/or Training:
  • Bachelor's degree in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry) or related field.
  • Master's degree or PhD preferred.

Minimum Experience:
  • Minimum Requirement: Bachelor's degree with 6+ years of relevant post-degree work in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry).
  • Experience Exception: Master's degree with 4+ years of relevant post-degree experience (OR) PhD with no experience.
  • Experience in at least one programming or scripting language and at least one statistical package, with R preferred.

Compensation
In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $86,320 - $154,960 per year for the role of Bioinformatics Research Scientist.
Explore our exceptional benefits!
St. Jude is an Equal Opportunity Employer
No Search Firms
St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

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