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Associate Scientist Cell Line Development Jobs in Tennessee

$61K/yr

... or teaching, test development, or medical research program experience that provided an ... Related fields include physiology, anatomy, molecular biology, cell biology, embryology, pathology ...

Line Cook

Chattanooga, TN · On-site

$14.25 - $18/hr

Summary The Line Cook prepares high-quality food items while maintaining consistency, safety ... Concord Hospitality invests in its associates by providing training and development at all levels ...

... development. Responsibilities: * Responsible for the design and conduct of experiments as defined ... Experience with cell culture techniques imperative * Hands-on experience with flow cytometry and ...

Associate Director, Data Science

Knoxville, TN · On-site

$56K - $56K/yr

You'll lead the strategy and development of proprietary tooling, work on brands with household recognition, and grow the team as the agency scales. The Associate Director, Data Science will report ...

Building trusted relationships with our network of engineering and sciences companies under our ... Monthly car allowance ($425/month) and monthly cell allowance ($100/month) after hourly paid ...

Building trusted relationships with our network of engineering and sciences companies under our ... Monthly car allowance ($425/month) and monthly cell allowance ($100/month) after hourly paid ...

Building trusted relationships with our network of engineering and sciences companies under our ... Monthly car allowance ($425/month) and monthly cell allowance ($100/month) after hourly paid ...

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Associate Scientist Cell Line Development information

What are some common challenges faced by Associate Scientists in Cell Line Development, and how can they be addressed?

Associate Scientists in Cell Line Development often encounter challenges such as optimizing cell growth conditions, maintaining cell line stability, and troubleshooting low productivity or contamination issues. Addressing these challenges requires strong attention to detail, effective documentation, and collaboration with cross-functional teams such as upstream process development and quality control. Regular communication with senior scientists and participation in team meetings can also help in problem-solving and ensuring project timelines are met. Staying updated on the latest techniques and technologies in cell line engineering further supports overcoming these obstacles.

What does an Associate Scientist in Cell Line Development do?

An Associate Scientist in Cell Line Development is responsible for creating and optimizing cell lines that are used in the production of biopharmaceutical products. Their work involves culturing cells, performing genetic modifications, and conducting experiments to select the best cell lines for manufacturing proteins or other biologics. They also document their findings, analyze data, and collaborate with other scientists to ensure the cell lines meet regulatory and quality standards. This role is vital in the early stages of drug development, as robust cell lines are essential for consistent and scalable production.

What is the difference between Associate Scientist Cell Line Development vs Associate Scientist Bioprocess Development?

AspectAssociate Scientist Cell Line DevelopmentAssociate Scientist Bioprocess Development
Required CredentialsBachelor's or Master's in Life Sciences, Molecular Biology, or related fieldsBachelor's or Master's in Biotechnology, Chemical Engineering, or related fields
Work EnvironmentLaboratory focused on cell line creation and characterizationLaboratory and pilot plant focused on process scale-up and manufacturing
Employer & Industry UsageBiotech and pharmaceutical companies developing cell lines for biologicsBiotech and pharma companies optimizing bioprocesses for production

Associate Scientist Cell Line Development primarily focuses on creating and characterizing cell lines for biologic production, while Associate Scientist Bioprocess Development concentrates on scaling up and optimizing manufacturing processes. Both roles require similar educational backgrounds and are essential in biologics development, but they differ in their specific focus within the biopharmaceutical pipeline.

What are the key skills and qualifications needed to thrive as an Associate Scientist in Cell Line Development, and why are they important?

To thrive as an Associate Scientist in Cell Line Development, you need a strong background in cell biology, molecular biology, and protein expression, typically supported by a relevant science degree. Familiarity with technical tools such as flow cytometry, cell culture systems, CRISPR gene editing platforms, and data analysis software is essential. Attention to detail, strong problem-solving abilities, and effective teamwork are standout soft skills in this role. These skills ensure high-quality cell line generation, reproducible results, and successful collaboration in fast-paced biopharmaceutical environments.
What are popular job titles related to Associate Scientist Cell Line Development jobs in Tennessee? For Associate Scientist Cell Line Development jobs in Tennessee, the most frequently searched job titles are:
What job categories do people searching Associate Scientist Cell Line Development jobs in Tennessee look for? The top searched job categories for Associate Scientist Cell Line Development jobs in Tennessee are:
What cities in Tennessee are hiring for Associate Scientist Cell Line Development jobs? Cities in Tennessee with the most Associate Scientist Cell Line Development job openings:
Computational Research Scientist in Yang Lab

Computational Research Scientist in Yang Lab

St. Jude Children's Research Hospital

Memphis, TN • On-site

Full-time

Posted 6 days ago


St. Jude Children's Research Hospital rating

8.4

Company rating: 8.4 out of 10

Based on 9 frontline employees who took The Breakroom Quiz

62nd of 995 rated hospitals


Job description

The Yang laboratory at the Center of Excellence for Structural Cell Biology at St Jude Children's Research Hospital invites applications for a Scientist position to contribute to the development of cryogenic correlative light and electron microscopy (cryo-CLEM). Cryo-CLEM leverages fluorescent signals to identify regions of interest and integrates cryo-electron microscopy/tomography to obtain high-resolution structural information from those same locations in their native, hydrated state. Despite significant progress in the field, current cryo-CLEM workflows remain labor-intensive and often suffer from low throughput and limited precision.
Our group specializes in in situ cryo-ET and in developing tools and workflows for efficient, accurate 2D/3D multimodal cryo-CLEM (Yang et al. J Struct Biol. 2021, Yang et al. Nat Methods 2023, Yang et al. Nat Protoc. 2026). We seek a highly motivated individual interested in developing innovative computational and imaging solutions to enhance the accuracy, robustness, and efficiency of 2D/3D correlative workflows.
Performs and/or coordinates a wide range of laboratory research procedures and conducts a spectrum of complex support tasks and projects determined by the field and scope of the particular research study. Performs a variety of laboratory techniques independently and presents results.
The successful candidate will have:
  • Advanced Degree (Preferably Ph.D.) in engineering, computational science, or related discipline
  • Expertise in machine learning and computer vision, and proficiency in program languages in Python, R, JavaScript, Git, Linux, MATLAB
  • Prior experience with image analysis and handling and software/tool development for workflow optimization is a plus
  • Strong problem-solving skills and the ability to design, execute and interpret computational and or imaging experiments
  • Motivation to learn new techniques and adapt to evolving technological needs
  • Ability of thrive in a multidisciplinary, collaborative environment with a respectful and team-oriented approach
  • High level of self-motivation, organization, and commitment to achieving project goals
  • Excellent oral and written communication skills

Job Responsibilities:
  • Lead computationally focused scientific research projects with moderate supervision from their PI.
  • Provide inputs regarding analytical approaches, set up analyses, and can develop new computational research methods with input from PI.
  • Identify, process, organize, summarize, review, and report relevant data.
  • Draft a manuscript and work through the submission and review process with input from the PI, as directed.
  • Instruct and provide guidance to other staff in basic computational research techniques and procedures.
  • (In the case of recent Ph.D. graduates, this position can be considered equivalent to a mentored postdoctoral position.)
  • Perform other duties as assigned to meet the goals and objectives of the department and institution.
  • Maintains regular and predictable attendance.

Minimum Education and/or Training:
  • Bachelor's degree in Bioinformatics, Molecular Biology, Biochemistry, Computer Science, or related field required.
  • Master's degree or PhD preferred.

Minimum Experience:
  • Minimum Requirement: Bachelor's degree and 6+ years of relevant experience.
  • Experience Exception: Master's degree and 4+ years of relevant experience (OR) PhD with no experience.
  • Rough criteria for this position based on publication output: 1-2 first author papers IF >5 (or equivalent contribution to other research outputs).
  • Prior experience in computational research techniques preferred.
  • Experience in project coordination, maintenance, and other research support activities preferred.

Our group is strongly committed to scientific rigor, mentorship, and supporting the professional development of team members at various stages of career advancement. St. Jude offers world-class high-resolution multimodal imaging and structural cell biology infrastructure. The successful candidate will have access to dedicated high performance computing (HPC) system, multiple Krios TEMs, advanced cryo-FIB-SEM systems including Hydra-bio, Arctics, and Aquilos II with integrated fluorescence , Zeiss Air-scan cryo-CLEM system, and plunge freezing systems including Vitrobot Mark IV, EMGP-2, and high pressure freezing systems. The lab is part of the Center of Excellence for Structural Cell Biology, providing an exceptional environment for interdisciplinary research in imaging, computation, and structural biology.
Compensation
In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $86,320 - $154,960 per year for the role of Computational Research Scientist in Yang Lab.
Explore our exceptional benefits!
St. Jude is an Equal Opportunity Employer
No Search Firms
St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.