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Associate Scientist Cell Line Development Jobs in Tennessee

St. Jude Children's Research Hospital

Postdoctoral Research Associate - Quantitative Microscopy and Live-Cell Chromatin Imaging Location ... developmental neurobiologists, biophysicists, optics experts, and data scientists to generate high ...

FC Renew

Senior Scientist

Knoxville, TN · On-site

$87K - $119K/yr

Our research and development is currently supported and funded by the U.S. Army, U.S. Department of ... Implementing and managing tests to characterize components, processes and fuel cell performances ...

FC Renew

Senior Scientist

Knoxville, TN · Hybrid

$87K - $119K/yr

Our research and development is currently supported and funded by the U.S. Army, U.S. Department of ... Implementing and managing tests to characterize components, processes and fuel cell performances ...

Vanderbilt University

Staff Scientist

Nashville, TN · On-site

D. in neuroscience, cell biology, developmental biology, molecular biology, or a related discipline - A strong publication record demonstrating scientific productivity and independence - Expertise in ...

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All JobsAssociate Scientist Cell Line Development JobsAssociate Scientist Cell Line Development Jobs in Tennessee

Associate Scientist Cell Line Development information

What does an associate scientist in cell line development do?

An Associate Scientist in Cell Line Development is responsible for creating and optimizing cell lines that are used in the production of biopharmaceutical products. Their work involves culturing cells, performing genetic modifications, and conducting experiments to select the best cell lines for manufacturing proteins or other biologics. They also document their findings, analyze data, and collaborate with other scientists to ensure the cell lines meet regulatory and quality standards. This role is vital in the early stages of drug development, as robust cell lines are essential for consistent and scalable production.

What are the key skills and qualifications needed to thrive as an associate scientist in cell line development?

To thrive as an Associate Scientist in Cell Line Development, you need a strong background in cell biology, molecular biology, and protein expression, typically supported by a relevant science degree. Familiarity with technical tools such as flow cytometry, cell culture systems, CRISPR gene editing platforms, and data analysis software is essential. Attention to detail, strong problem-solving abilities, and effective teamwork are standout soft skills in this role. These skills ensure high-quality cell line generation, reproducible results, and successful collaboration in fast-paced biopharmaceutical environments.

What are some common challenges faced by associate scientists in cell line development, and how can they be addressed?

Associate Scientists in Cell Line Development often encounter challenges such as optimizing cell growth conditions, maintaining cell line stability, and troubleshooting low productivity or contamination issues. Addressing these challenges requires strong attention to detail, effective documentation, and collaboration with cross-functional teams such as upstream process development and quality control. Regular communication with senior scientists and participation in team meetings can also help in problem-solving and ensuring project timelines are met. Staying updated on the latest techniques and technologies in cell line engineering further supports overcoming these obstacles.

What is the difference between Associate Scientist Cell Line Development vs Associate Scientist Bioprocess Development?

AspectAssociate Scientist Cell Line DevelopmentAssociate Scientist Bioprocess Development
Required CredentialsBachelor's or Master's in Life Sciences, Molecular Biology, or related fieldsBachelor's or Master's in Biotechnology, Chemical Engineering, or related fields
Work EnvironmentLaboratory focused on cell line creation and characterizationLaboratory and pilot plant focused on process scale-up and manufacturing
Employer & Industry UsageBiotech and pharmaceutical companies developing cell lines for biologicsBiotech and pharma companies optimizing bioprocesses for production

Associate Scientist Cell Line Development primarily focuses on creating and characterizing cell lines for biologic production, while Associate Scientist Bioprocess Development concentrates on scaling up and optimizing manufacturing processes. Both roles require similar educational backgrounds and are essential in biologics development, but they differ in their specific focus within the biopharmaceutical pipeline.

What cities in Tennessee are hiring for Associate Scientist Cell Line Development jobs?

Cities in Tennessee with the most Associate Scientist Cell Line Development job openings:

Scientist - Development in Therapeutics Production & Quality

Memphis, TN • On-site

St. Jude Children's Research Hospital
Health Care and Social Assistance • 1 - 5K employees
Learn more about St. Jude Children's Research Hospitalexternal

$86K - $154K/yr

Other

Posted 26 days ago

St. Jude Children's Research Hospital rating

8.8

Company rating: 8.8 out of 10

Based on 13 frontline employees who took The Breakroom Quiz

Job description

Scientist - Development in Therapeutics Production & Quality

Location

Memphis, TN

Category

Laboratory Sciences & Support

Department

GMP & TPQ

Shift

Weekday Day

Position Type

Full Time

Scheduled Weekly Hours

40

JR7494

Job Description

Join our Team!

The Therapeutics Production and Quality department within our Good Manufacturing Practices (GMP) facility is looking for a Scientist - Development to design and implement process development experiments with minimal supervision including both upstream and downstream unit operations. In this role you will perform small scale cell culture experiments, set up and run bioreactors for culture of mammalian or bacterial cells, and optimize purification methods using various chromatography techniques. Experience in mammalian and bacterial cell culture, bioreactors, protein purification, plasmid DNA purification, tangential flow filtration and various other filtration techniques is preferred. You will generate purified plasmid DNA and gene therapy vectors including Lentiviral.

Job Responsibilities:

  • Coordinate multiple aspects of projects/processes within area (GMP/ECTL) with guidance, and execute processes (e.g., tech transfer & scale-up runs, HPLC/biologic assays, manufacturing of cellular therapeutics) utilizing appropriate techniques, equipment, and methods.

  • Provide inputs regarding revisions to SOPs and/or process flows within area.

  • Support development, documentation, and reporting of relevant experimental data (e.g., production batch records, HPLC reports, summary reports for manufacturing campaigns).

  • Monitor and document compliance with quality and regulatory requirements; and address deviations.

  • Support monitoring and stocking of supplies, and calibration, maintenance, troubleshooting, and purchase of equipment within area.

  • Instruct other staff in basic techniques, procedures, and systems within area (e.g., operations of cGMP equipment and control software).

  • Perform other duties as assigned to meet the goals and objectives of the department and institution.

  • Maintains regular and predictable attendance.

Minimum Education and/or Training:

  • Bachelor's degree required.

  • Master's OR PhD preferred.

Minimum Experience:

  • Minimum Requirement: Bachelor's degree with 7+ years experience in relevant scientific area (e.g., GMP: chemistry, biology, chemical engineering, analytical chemistry, biotechnology; ECTL: cellular biology, molecular biology, immunology, biochemistry).

  • Experience exception: 5+ years of experience in relevant area with Master's

  • Experience exception: 3+ years of experience in relevant area with PhD

  • Prior experience in relevant area to own domain (e.g., upstream/downstream cGMP experience, process development, HPLC/biological assays) strongly preferred.

  • Experience in lab and scientific project coordination, maintenance, and other research support activities preferred.

Compensation

In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $86,320 - $154,960 per year for the role of Scientist - Development in Therapeutics Production & Quality.

Explore our exceptional benefits !

St. Jude is an Equal Opportunity Employer

No Search Firms

St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

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