1

Associate Scientist Cell Line Development Jobs in Tennessee

Research Associate 2

Oak Ridge, TN · On-site +1

$35.19 - $48.95/hr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

... cell, genomics, transcriptomics, proteomics, metabolomics) and biological entities (e.g., cell ... or development of reproducible computational workflows, scientific publication and presentation ...

... development. Responsibilities: * Responsible for the design and conduct of experiments as defined ... Experience with cell culture techniques imperative * Hands-on experience with flow cytometry and ...

Research Associate 2

Oak Ridge, TN · On-site +1

$35.19 - $48.95/hr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

... cell, genomics, transcriptomics, proteomics, metabolomics) and biological entities (e.g., cell ... or development of reproducible computational workflows, scientific publication and presentation ...

Research Associate 2

Oak Ridge, TN · On-site +1

$35.19 - $48.95/hr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

... cell, genomics, transcriptomics, proteomics, metabolomics) and biological entities (e.g., cell ... or development of reproducible computational workflows, scientific publication and presentation ...

Sales Development Representative

Franklin, TN · On-site

$343K/yr

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

Building trusted relationships with our network of engineering and sciences companies under our ... Monthly car allowance ($425/month) and monthly cell allowance ($100/month) after hourly paid ...

Showing results 21-40

Associate Scientist Cell Line Development information

What are some common challenges faced by associate scientists in cell line development, and how can they be addressed?

Associate Scientists in Cell Line Development often encounter challenges such as optimizing cell growth conditions, maintaining cell line stability, and troubleshooting low productivity or contamination issues. Addressing these challenges requires strong attention to detail, effective documentation, and collaboration with cross-functional teams such as upstream process development and quality control. Regular communication with senior scientists and participation in team meetings can also help in problem-solving and ensuring project timelines are met. Staying updated on the latest techniques and technologies in cell line engineering further supports overcoming these obstacles.

What does an associate scientist in cell line development do?

An Associate Scientist in Cell Line Development is responsible for creating and optimizing cell lines that are used in the production of biopharmaceutical products. Their work involves culturing cells, performing genetic modifications, and conducting experiments to select the best cell lines for manufacturing proteins or other biologics. They also document their findings, analyze data, and collaborate with other scientists to ensure the cell lines meet regulatory and quality standards. This role is vital in the early stages of drug development, as robust cell lines are essential for consistent and scalable production.

What is the difference between Associate Scientist Cell Line Development vs Associate Scientist Bioprocess Development?

AspectAssociate Scientist Cell Line DevelopmentAssociate Scientist Bioprocess Development
Required CredentialsBachelor's or Master's in Life Sciences, Molecular Biology, or related fieldsBachelor's or Master's in Biotechnology, Chemical Engineering, or related fields
Work EnvironmentLaboratory focused on cell line creation and characterizationLaboratory and pilot plant focused on process scale-up and manufacturing
Employer & Industry UsageBiotech and pharmaceutical companies developing cell lines for biologicsBiotech and pharma companies optimizing bioprocesses for production

Associate Scientist Cell Line Development primarily focuses on creating and characterizing cell lines for biologic production, while Associate Scientist Bioprocess Development concentrates on scaling up and optimizing manufacturing processes. Both roles require similar educational backgrounds and are essential in biologics development, but they differ in their specific focus within the biopharmaceutical pipeline.

What are the key skills and qualifications needed to thrive as an associate scientist in cell line development?

To thrive as an Associate Scientist in Cell Line Development, you need a strong background in cell biology, molecular biology, and protein expression, typically supported by a relevant science degree. Familiarity with technical tools such as flow cytometry, cell culture systems, CRISPR gene editing platforms, and data analysis software is essential. Attention to detail, strong problem-solving abilities, and effective teamwork are standout soft skills in this role. These skills ensure high-quality cell line generation, reproducible results, and successful collaboration in fast-paced biopharmaceutical environments.

What cities in Tennessee are hiring for Associate Scientist Cell Line Development jobs?

Cities in Tennessee with the most Associate Scientist Cell Line Development job openings:

Bioinformatics Research Scientist / Senior Bioinformatics Research Scientist - Northcott Lab in the

St. Jude Children's Research Hospital

Memphis, TN • On-site

Full-time

Re-posted 21 days ago


St. Jude Children's Research Hospital rating

8.6

Company rating: 8.6 out of 10

Based on 12 frontline employees who took The Breakroom Quiz

41st of 1,059 rated hospitals


Job description

The Northcott Lab in the Center of Excellence in Neuro-Oncology Sciences (CENOS) at St. Jude Children's Research Hospital is seeking a highly motivated Bioinformatics Research Scientitst or Senior Bioinformatics Research Scientist. CENOS is a collaborative research environment that aims to drive discoveries needed to improve outcomes for children with brain tumors. Through application of cutting-edge molecular profiling to unprecedented patient cohorts and innovative model systems, CENOS members are rapidly translating laboratory findings into new treatments. Genome-wide studies of diverse pediatric brain tumor entities have identified novel mutations, defined molecular subgroups, and opened new avenues of basic, translational, and clinical investigation.
The Senior Bioinformatics Research Scientist performs data analysis, data visualization, statistical analysis, experimental design, database development, mathematical modeling, and novel method development. Provides bioinformatics analysis for investigators and communicates analytical process and results.
The Bioinformatics Research Scientist is responsible for designing, developing, improving, modifying, and operating data analysis pipelines. Manages projects and coordinates other efforts related to analysis and infrastructure as directed.
The successful candidate will contribute to discovery-driven computational studies of unprecedented multi-omic datasets obtained from children with malignant brain cancer, including single-cell, spatial, and liquid biopsy profiles. The candidate will work closely with other bioinformatics personnel within CENOS to play an integral role in exciting collaborations, both within St. Jude and with prominent external collaborators. A deep understanding of cancer genomics, human genetics, transcriptomics, or epigenetics, strong problem-solving skills, attention to detail, and critical thinking are essential for this position. The successful recruit must have the capacity to execute proficient computational analyses and troubleshooting independently, communicate effectively with the PI and collaborators, and thrive in a highly collaborative team environment.
Senior Bioinformatics Research Scientist
The ideal candidate should have:
  • A PhD in bioinformatics, computational biology, data science or related field.
  • Experience analyzing the following platforms: Single-cell/nucleus RNA-seq, spatial transcriptomics, RNA-seq, ATAC-seq, ChIP-seq/CUT&RUN, and DNA methylation
  • A strong CV that includes publications involving cancer genomics, epigenomics, single-cell, spatial 'omics, machine learning, and artificial intelligence.
  • Experience in analyzing, interpreting, and visualizing human genomics datasets generated by high-throughput sequencing platforms including short- (Illumina) and long-read- (e.g. PacBio and Oxford Nanopore) whole-genome sequencing.
  • Proficiency in relevant programming languages such as R and Python, preferably in a High-Performance Computing (HPC) environment.
  • Proficiency in tools for ensuring reproducibility of pipelines, such as workflow management systems (e.g., nextflow or snakemake), and version control (e.g., git).
  • Extensive expertise in data integration and harmonization.
  • Proven problem-solving skills and collaborative nature in fast-paced environment.
  • Excellent communication and presentation skills.

Job Responsibilities:
  • Provide research support and deliver high-quality results by formulating an efficient analytical approach with the available data.
  • Deliver data files, and document the analytical process. May participate in manuscript preparation at project's conclusion.
  • Assist with establishing and documenting protocols or best practices for common research tasks, and in the formulation of analytical plans that use the best approach to address challenging data analysis questions.
  • Assist in the evaluation and testing of new methods and technologies.
  • Contribute ideas to automate or improve existing analysis methods. Implement the improvement or work with others to do so.
  • Participate in the department's developmental projects and interdepartmental team projects.
  • Perform other duties as assigned to meet the goals and objectives of the department and institution.
  • Maintains regular and predictable attendance.

Minimum Education and/or Training:
  • Bachelor's degree in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry) or related field.
  • Master's degree or PhD preferred.

Minimum Experience:
  • Minimum Requirement: Bachelor's degree with 7+ years of relevant post-degree work in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry).
  • Experience Exception: Master's degree with 5+ years of relevant post-degree experience (OR) PhD with 2+ years of relevant post-degree experience.
  • Significant experience in at least one programming or scripting language and at least one statistical package, with R preferred.

Bioinformatics Research Scientist
Job Responsibilities:
  • Independently perform basic and advanced level statistical analysis, algorithm implementation, programming from a variety of biotechnology platforms, and oversee quality check.
  • Design and prepare materials and courses for training on various bioinformatics software and databases, computing, data mining, and analysis.
  • Act as a liaison between end-users, software developers, system designers, and different departments.
  • Establish protocols or best practices for common research tasks and SOP, evaluate products and solutions to make recommendations, and integrate solutions.
  • Lead the development, implementation, installation, and maintenance of databases; coordinate data collection, database implementation, and usage and any hardware and software related to database collection.
  • Develop programs to assist in the analysis of data within the databases.
  • Assist in planning, coordinating, and organizing projects across departments and delegate tasks based on priority, expertise, and capacity.
  • Perform other duties as assigned to meet the goals and objectives of the department and institution.
  • Maintains regular and predictable attendance.

Minimum Education and/or Training:
  • Bachelor's degree in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry) or related field.
  • Master's degree or PhD preferred.

Minimum Experience:
  • Minimum Requirement: Bachelor's degree with 6+ years of relevant post-degree work in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry).
  • Experience Exception: Master's degree with 4+ years of relevant post-degree experience (OR) PhD with no experience.
  • Experience in at least one programming or scripting language and at least one statistical package, with R preferred.

Compensation
In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $104,000 - $186,160 per year for the role of Bioinformatics Research Scientist / Senior Bioinformatics Research Scientist - Northcott Lab in the Center of Excellence in Neuro-Oncology Sciences (CENOS).
Explore our exceptional benefits!
St. Jude is an Equal Opportunity Employer
No Search Firms
St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

What St. Jude Children's Research Hospital employees say

Pay

Benefits

Hours and flexibility

Workplace

Get the full story on Breakroom