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Associate Downstream Process Development Scientist Jobs

Lundbeck

Downstream Development Associate II

Bothell, WA · On-site

$38 - $45/hr

... Process Science & Validation Team. The Lu-SBP team leads and supports the development of new ... Summary: Performs downstream process development experiments and supporting activities, which ...

MSD

Biologics Process Development Scientific Lead

Rahway, NJ · On-site

$105K - $136K/yr

The Scientific Lead partners closely with upstream and downstream process development to support integrated development strategies. The role provides subject matter expertise, influences technical ...

Lonza

Scientist II, Downstream

Houston, TX · On-site

Scientist II, Downstream Location: This is an on-site position located in Pearland, TX. The purpose ... The ideal candidate will be responsible for leading new process development and improving existing ...

Lonza

Scientist II, Downstream

Houston, TX · On-site

Scientist II, Downstream Location: This is an on-site position located in Pearland, TX. The purpose ... The ideal candidate will be responsible for leading new process development and improving existing ...

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How much do associate downstream process development scientist jobs pay per hour?

As of Jul 10, 2026, the average hourly pay for associate downstream process development scientist in the United States is $33.68, according to ZipRecruiter salary data. Most workers in this role earn between $27.64 and $41.35 per hour, depending on experience, location, and employer.

What is an Associate Downstream Process Development Scientist?

An Associate Downstream Process Development Scientist is a professional who works in the biotechnology or pharmaceutical industry, focusing on developing and optimizing processes that purify biological products, such as proteins or antibodies, after they have been produced by cells. Their work is crucial for ensuring the final product meets quality and safety standards before it is used in research or clinical applications. They typically perform laboratory experiments, analyze data, and collaborate with other scientists and engineers to improve yield and efficiency. This role is often entry-level or early-career, providing hands-on experience in process development and technical troubleshooting.

What are the key skills and qualifications needed to thrive as an Associate Downstream Process Development Scientist, and why are they important?

To excel as an Associate Downstream Process Development Scientist, you need a solid understanding of biochemistry, chemical engineering, and downstream purification techniques, often supported by a bachelor's or master's degree in a life science or engineering discipline. Familiarity with chromatographic systems (such as AKTA), filtration equipment, and analytical tools, as well as knowledge of GMP/GLP regulations, is typically required. Strong problem-solving, attention to detail, and effective teamwork and communication skills help you navigate complex experiments and collaborate with cross-functional teams. These skills ensure efficient process optimization, compliance with regulatory standards, and successful development of biopharmaceutical products.

What is the difference between Associate Downstream Process Development Scientist vs Associate Upstream Process Development Scientist?

AspectAssociate Downstream Process Development ScientistAssociate Upstream Process Development Scientist
Primary FocusPurification and recovery of bioproductsCell culture and fermentation processes
Required SkillsProtein purification, chromatography, filtrationCell culture, bioreactor operation, media preparation
Work EnvironmentLaboratories, manufacturing facilitiesLaboratories, bioreactor labs
Common CertificationsBiotech or bioprocessing certificationsBiotech or bioprocessing certifications

Both roles are essential in biopharmaceutical development, focusing on different stages of the production process. The Associate Downstream Process Development Scientist specializes in purification techniques, while the Associate Upstream Process Development Scientist concentrates on cell growth and fermentation. Understanding these distinctions helps candidates target their skills and career paths effectively.

What are some typical challenges faced by an Associate Downstream Process Development Scientist, and how can they be addressed?

Associate Downstream Process Development Scientists often encounter challenges such as optimizing purification processes, troubleshooting equipment performance, and ensuring batch-to-batch consistency. These challenges can be addressed by maintaining meticulous documentation, collaborating closely with upstream and analytical teams, and staying current with best practices in chromatography and filtration. Proactively seeking feedback from experienced colleagues and participating in cross-functional meetings can also help in identifying solutions and improving process efficiency.
What cities are hiring for Associate Downstream Process Development Scientist jobs? Cities with the most Associate Downstream Process Development Scientist job openings:
What are the most commonly searched types of Downstream Process Development Scientist jobs? The most popular types of Downstream Process Development Scientist jobs are:
What states have the most Associate Downstream Process Development Scientist jobs? States with the most job openings for Associate Downstream Process Development Scientist jobs include:
Associate Downstream Process Development Scientist jobs near you
Downstream Development Associate II

Downstream Development Associate II

Lundbeck

Bothell, WA • On-site

$38 - $45/hr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Re-posted 6 days ago

Job description

Do you want to join a team where the mission is meaningful, the challenges are complex, and you can directly see the results of your hard work? Lundbeck Seattle BioPharmaceuticals (Lu-SBP), located in Bothell, Washington, is the Process Development Center of Excellence for Biologics within the global Lundbeck CMC organization. Since integrating into Lundbeck in October 2019, Lu-SBP has supported commercial launch of Lundbeck's first biologic product (Vyepti) and advancement of a growing biologics pipeline in collaboration with our Copenhagen-based Process Science & Validation Team. The Lu-SBP team leads and supports the development of new product candidates from cell line development through commercial validation of Drug Substance and Drug Product manufacturing processes. Join us on our journey to advance brain health and transform lives.
Summary:
Performs downstream process development experiments and supporting activities, which enable both early and late-stage manufacturing process design for therapeutic monoclonal antibody production via yeast and mammalian expression systems.
Essential Functions:
  • Performs small-scale downstream process development experiments for monoclonal antibodies, as applied to liquid chromatography and tangential/normal flow filtration.
  • Prepares experimental intermediate samples for further analytical testing, including purification via miniature liquid chromatography and ultrafiltration devices.
  • Prepares purified protein product to support upstream process development and supply further downstream process development activities.
  • Performs analytical methods, such as UV-visible spectrophotometry, turbidimetry, density measurement, size exclusion and protein A affinity HPLC, and biolayer interferometry.
  • Organizes and analyzes primary data and prepares concise presentations and reports.

Required Education, Experience, and Skills:
  • Accredited bachelor's degree and a minimum of 2+ years of biotechnology/pharmaceutical industry experience or equivalent combination of education and experience totaling 4 years.
  • Basic understanding of the principles of liquid chromatography, membrane filtration, sedimentation/centrifugation, aqueous physical chemistry, and protein chemistry.
  • Familiar with basic laboratory equipment, including pH, conductivity, & temperature meters, pumps, pressure gauges, weight scales, pipette dispensers, and tabletop centrifuges.
  • Excellent verbal communication skills to interact collaboratively with Process Development teammates.
  • Well-developed organizational skills and the ability to take a proactive approach to job responsibilities.
  • Ability to comply with FDA GMP documentation regulations and industry standard safety practices.
  • Proficiency in Microsoft Windows 10/Office.
  • Must be able to lift to 30 pounds on occasion.

Preferred Qualifications, Skills and Competencies
  • An accredited B.S. degree in science or engineering (i.e. Biochemical Engineering, Chemical Engineering, Biotechnology Engineering, Biochemistry, Biotechnology or equivalent).
  • Experience with analytical techniques such as HPLC, UPLC, and/or CE a plus.
  • Experience with pilot scale operations a plus.
  • Experience with MPLC systems such as the Äkta/Unicorn platform a plus.

The range displayed is specifically for those potential hires who will work or reside in the state of Washington, if selected for this role, and may vary based on various factors such as the candidate's qualifications, skills, competencies and proficiency for the role. Salary Pay Range: $38/hour - $45/hour and eligibility for an 8% bonus target based on company and individual performance. Additional benefits for this position include flexible paid time off (PTO), health benefits to include Medical, Dental and Vision and company match 401k. Additional benefits information can be found on our site.
Why Lundbeck
Lundbeck offers a robust and comprehensive benefits package to help employees live well and protect their health, family, and everyday life. Information regarding our benefit offering can be found on the U.S. career site.
Lundbeck is committed to working with and providing reasonable accommodations to disabled veterans and other individuals with disabilities during our employment application process. If, because of a disability, you need a reasonable accommodation for any part of the application process, please visit the U.S. career site.
Lundbeck is proud to be an equal opportunity workplace. We are committed to equal employment opportunity regardless of race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status, and any other characteristic protected by law, rule, or regulation. Lundbeck participates in E-Verify.
About Lundbeck
At Lundbeck, our most important contribution is easing the burden of the millions of people living with brain disorders. Whether it is migraine, depression, or other brain disorders, patients, their carers, and society as a whole depend on us.
Through cutting edge science and strong partnerships, we develop and market some of the world's leading treatments, expanding into neuro-specialty and neuro-rare from our strong legacy within psychiatry and neurology.
The brain health challenge is real. Our commitment is real. Our impact is real.
About Lundbeck
At Lundbeck, our most important contribution is easing the burden of the millions of people living with brain disorders. Whether it is migraine, depression, or other brain disorders, patients, their carers, and society as a whole depend on us.
Through cutting edge science and strong partnerships, we develop and market some of the world's leading treatments, expanding into neuro-specialty and neuro-rare from our strong legacy within psychiatry and neurology.
The brain health challenge is real. Our commitment is real. Our impact is real.

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