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Associate Downstream Process Development Scientist Jobs in Colorado

Agilent

Process Engineer, Downstream

Frederick, CO · On-site

$124.16K - $194K/yr

We provide life science, diagnostic and applied market laboratories worldwide with instruments ... Support Chemical Development in the development, characterization, and scaleup of innovative ...

Agilent

R&D Scientist

Boulder, CO · On-site

$127.68K - $199.50K/yr

... and downstream processes at the lab scale for tech transfer to large-scale oligonucleotide ... for scientific and technical leadership of oligonucleotide process research and development ...

Agilent

R&D Scientist

Boulder, CO

$127.68K - $199.50K/yr

... and downstream processes at the lab scale for tech transfer to large-scale oligonucleotide ... for scientific and technical leadership of oligonucleotide process research and development ...

Agilent

Process Engineer, Downstream

Frederick, CO

$124.16K - $194K/yr

We provide life science, diagnostic and applied market laboratories worldwide with instruments ... SupportChemical Development inthe development,characterization, and scaleupof innovative ...

Agilent

Research Associate, Process Development

Boulder, CO · On-site

$87.60K - $136.88K/yr

... development and toxicology studies. * Prepares process descriptions and the writing of writes ... Bachelor's or Master's Degree in chemistry, chemical engineering, science or equivalent or a ...

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Associate Downstream Process Development Scientist information

What are the key skills and qualifications needed to thrive as an Associate Downstream Process Development Scientist, and why are they important?

To excel as an Associate Downstream Process Development Scientist, you need a solid understanding of biochemistry, chemical engineering, and downstream purification techniques, often supported by a bachelor's or master's degree in a life science or engineering discipline. Familiarity with chromatographic systems (such as AKTA), filtration equipment, and analytical tools, as well as knowledge of GMP/GLP regulations, is typically required. Strong problem-solving, attention to detail, and effective teamwork and communication skills help you navigate complex experiments and collaborate with cross-functional teams. These skills ensure efficient process optimization, compliance with regulatory standards, and successful development of biopharmaceutical products.

What are some typical challenges faced by an Associate Downstream Process Development Scientist, and how can they be addressed?

Associate Downstream Process Development Scientists often encounter challenges such as optimizing purification processes, troubleshooting equipment performance, and ensuring batch-to-batch consistency. These challenges can be addressed by maintaining meticulous documentation, collaborating closely with upstream and analytical teams, and staying current with best practices in chromatography and filtration. Proactively seeking feedback from experienced colleagues and participating in cross-functional meetings can also help in identifying solutions and improving process efficiency.

What is an Associate Downstream Process Development Scientist?

An Associate Downstream Process Development Scientist is a professional who works in the biotechnology or pharmaceutical industry, focusing on developing and optimizing processes that purify biological products, such as proteins or antibodies, after they have been produced by cells. Their work is crucial for ensuring the final product meets quality and safety standards before it is used in research or clinical applications. They typically perform laboratory experiments, analyze data, and collaborate with other scientists and engineers to improve yield and efficiency. This role is often entry-level or early-career, providing hands-on experience in process development and technical troubleshooting.

What is the difference between Associate Downstream Process Development Scientist vs Associate Upstream Process Development Scientist?

AspectAssociate Downstream Process Development ScientistAssociate Upstream Process Development Scientist
Primary FocusPurification and recovery of bioproductsCell culture and fermentation processes
Required SkillsProtein purification, chromatography, filtrationCell culture, bioreactor operation, media preparation
Work EnvironmentLaboratories, manufacturing facilitiesLaboratories, bioreactor labs
Common CertificationsBiotech or bioprocessing certificationsBiotech or bioprocessing certifications

Both roles are essential in biopharmaceutical development, focusing on different stages of the production process. The Associate Downstream Process Development Scientist specializes in purification techniques, while the Associate Upstream Process Development Scientist concentrates on cell growth and fermentation. Understanding these distinctions helps candidates target their skills and career paths effectively.

What are the most commonly searched types of Downstream Process Development Scientist jobs in Colorado? The most popular types of Downstream Process Development Scientist jobs in Colorado are:
What cities in Colorado are hiring for Associate Downstream Process Development Scientist jobs? Cities in Colorado with the most Associate Downstream Process Development Scientist job openings:
Associate Downstream Process Development Scientist jobs near you
Downstream Process Development Associate Scientist

Downstream Process Development Associate Scientist

KBI Biopharma, Inc.

Boulder, CO • On-site

$85.76K - $117.92K/yr

Full-time

Posted 17 days ago

Job description

JOB SUMMARY
The Downstream Process Development (PD) Associate Scientist provides process development input and co-ownership for a product, including all development and design decisions, with oversight and mentorship from senior process development staff. They learn to apply scientific principles to design and execute laboratory studies for unit operation development and optimization. They possess a developing working knowledge of the downstream functional area with developing aptitude in one or more operations, including chromatography and tangential flow filtration. They author and review technical documents including protocols and reports commensurate with PD compliance and quality standards. This workflow encompasses process development scope as well as support of technology transfer activities in preparation for cGMP production. The PD Scientist I is responsible for maintaining training compliance, according to site expectations. This is a salaried exempt position, with the expectation to cover shift work as needed to support laboratory activities and organizational need.
Responsibilities
  • Executes process development, process characterization, and technology transfer of microbial processes to commercial cGMP facility.
  • Works toward developing a broad knowledge of state-of-the-art principles and theory.
  • Responsible for producing high quality documentation and client reports suitable for publication and regulatory requirements. Compiles and presents data to clients.
  • Supports downstream process development efforts in the laboratory and manufacturing areas. Executes experiments with oversight and support. Conceptualizes and proposes process development and manufacturing based on process data. Execution includes downstream unit operations such as chromatography, tangential flow filtration, normal filtration, as well as sampling and basic analysis of process samples; concentration, pH, and conductivity.
  • Will assist in the downstream portion of development, process characterization, and/or technology transfer programs.
  • Provide technical support for cGMP manufacturing through floor coverage, batch document review, and support of deviations and change controls with mentor/managerial oversight.
  • Responsible for developing/maintaining a current understanding of cGMP and other regulatory requirements.
  • Documents procedures, observations, and results in laboratory notebooks and responsible for maintaining training compliance, according to site expectation. Reviews documentation and records as assigned.
  • May contribute to the evaluation, development and implementation of new downstream technologies leading to process improvements and efficiency of operation in support of downstream process development and manufacturing activities.
  • Adheres to all safety requirements and assures that departmental employees comply with required safety procedures.
  • Reacts to change productively and handles other essential tasks as assigned

REQUIREMENTS
B.S. degree and a minimum of 5+ years of related experience; M.S. and 3+ years of related experience or Ph.D. and 0+ years related experience in a scientific discipline.
Experience with downstream process development and chromatography equipment required. Excellent written and verbal communication skills, focus on customer service, and ability to meet strict client deadlines. Highly collaborative. Flexibility of hours to support downstream processes. Knowledge of GMPs and biotechnology-derived product regulations preferred.
Salary: $85,760-$117,920
KBI Biopharma, Inc. is an EEO/AA employer and actively seeks to diversify its work force. Therefore, all qualified applicants, regardless of race, color, national origin, religion, gender, gender identity, sexual orientation, age, disability or veteran status, are strongly encouraged to apply.
I understand that neither the completion of this application nor any other part of my consideration for employment establishes any obligation for KBI Biopharma, Inc. to hire me. If I am hired, I understand that either KBI Biopharma, Inc. or I can terminate my employment at any time and for any reason, with or without cause and without prior notice. I understand that no representative of KBI Biopharma, Inc. has the authority to make any assurance to the contrary.
I attest with my signature below that I have given to KBI Biopharma, Inc. true and complete information on this application. No requested information has been concealed. I authorize KBI Biopharma, Inc. to contact references provided for employment reference checks. If any information I have provided is untrue, or if I have concealed material information, I understand that this will constitute cause for the denial of employment or immediate dismissal.

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