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Associate Downstream Process Development Scientist Jobs in Worcester, MA

Integrated Resources INC

Biprocess Engineer

Devens, MA · On-site

Process Engineer Scientific: * MS&T organization is seeking to fill a Process Engineer position for ... Prior experience (Ph.D.: 0 - 2 years; BS/MS: 2 - 6 years) in process development, process ...

AT Process Technologies

Process Chemist

Waltham, MA · On-site

$130K - $200K/yr

Summary We are seeking a process development chemist to own and execute the research, development ... Develop and optimize core synthesis and downstream processing, evaluating competing technical ...

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All JobsAssociate Downstream Process Development Scientist JobsAssociate Downstream Process Development Scientist Jobs in Worcester, MA

Associate Downstream Process Development Scientist information

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How much do associate downstream process development scientist jobs pay per hour?

As of Aug 31, 2026, the average hourly pay for associate downstream process development scientist in Worcester, MA is $33.61, according to ZipRecruiter salary data. Most workers in this role earn between $27.60 and $41.25 per hour, depending on experience, location, and employer.

What is an associate downstream process development scientist?

An Associate Downstream Process Development Scientist is a professional who works in the biotechnology or pharmaceutical industry, focusing on developing and optimizing processes that purify biological products, such as proteins or antibodies, after they have been produced by cells. Their work is crucial for ensuring the final product meets quality and safety standards before it is used in research or clinical applications. They typically perform laboratory experiments, analyze data, and collaborate with other scientists and engineers to improve yield and efficiency. This role is often entry-level or early-career, providing hands-on experience in process development and technical troubleshooting.

What are some typical challenges faced by an associate downstream process development scientist, and how can they be addressed?

Associate Downstream Process Development Scientists often encounter challenges such as optimizing purification processes, troubleshooting equipment performance, and ensuring batch-to-batch consistency. These challenges can be addressed by maintaining meticulous documentation, collaborating closely with upstream and analytical teams, and staying current with best practices in chromatography and filtration. Proactively seeking feedback from experienced colleagues and participating in cross-functional meetings can also help in identifying solutions and improving process efficiency.

What are the key skills and qualifications needed to thrive as an associate downstream process development scientist, and why are they important?

To excel as an Associate Downstream Process Development Scientist, you need a solid understanding of biochemistry, chemical engineering, and downstream purification techniques, often supported by a bachelor's or master's degree in a life science or engineering discipline. Familiarity with chromatographic systems (such as AKTA), filtration equipment, and analytical tools, as well as knowledge of GMP/GLP regulations, is typically required. Strong problem-solving, attention to detail, and effective teamwork and communication skills help you navigate complex experiments and collaborate with cross-functional teams. These skills ensure efficient process optimization, compliance with regulatory standards, and successful development of biopharmaceutical products.

What is the difference between Associate Downstream Process Development Scientist vs Associate Upstream Process Development Scientist?

AspectAssociate Downstream Process Development ScientistAssociate Upstream Process Development Scientist
Primary FocusPurification and recovery of bioproductsCell culture and fermentation processes
Required SkillsProtein purification, chromatography, filtrationCell culture, bioreactor operation, media preparation
Work EnvironmentLaboratories, manufacturing facilitiesLaboratories, bioreactor labs
Common CertificationsBiotech or bioprocessing certificationsBiotech or bioprocessing certifications

Both roles are essential in biopharmaceutical development, focusing on different stages of the production process. The Associate Downstream Process Development Scientist specializes in purification techniques, while the Associate Upstream Process Development Scientist concentrates on cell growth and fermentation. Understanding these distinctions helps candidates target their skills and career paths effectively.

What are the most commonly searched types of Downstream Process Development Scientist jobs in Worcester, MA?

The most popular types of Downstream Process Development Scientist jobs in Worcester, MA are:

What cities near Worcester, MA are hiring for Associate Downstream Process Development Scientist jobs?

Cities near Worcester, MA with the most Associate Downstream Process Development Scientist job openings:

Associate Downstream Process Development Scientist jobs near you

Associate Formulation Development Scientist

Hopkinton, MA • On-site

Phosphorex LLC
1 - 10 employees
Learn more about Phosphorex LLCexternal

Full-time

Re-posted 7 days ago

Job description

Description

The Associate Scientist is a specialist in the formulation and characterization of particulate based drug delivery systems including lipid and polymeric nanoparticles.  The Associate Scientist participates in the development and optimization of formulations to enable cell and tissue targeting contributing to the development of novel therapeutics.  They perform hands-on experiments in a laboratory setting, leading the execution of upstream (buffer prep, emulsification, microfluidics) and downstream (buffer exchange, concentration, etc.) formulation development activities.  The Associate Scientist is a team player who has laboratory and technical experience with a high attention to detail and desire to work in a fast-paced environment and contribute to a result orientated team.  

Role and Responsibilities

  • Assist in development and optimization of particulate based drug delivery systems to enable delivery of nucleic acids, peptides and small molecules for cell and tissue targeting by:   
  • Preparing polymeric and lipid-based microsphere and nanoparticle formulations via microfluidics, emulsification, etc.  
  • Purification and downstream processing of formulations via dialysis, centrifugation and tangential flow filtration  
  • Characterization of formulations including particle size analysis, zeta potential, drug content, encapsulation efficiency and in vitro release 
  • Evaluating short term stability of frozen and lyophilized formulations to support proof of concept animal studies. 
  • Collaborate with project team(s) to define and execute project plans to facilitate the development and optimization of formulations and processes to support feasibility and pre-clinical studies. 
  • Work collaboratively across multiple departments (Operations, Analytical Services, Process Development) to facilitate project teams' ability to successfully meet project objectives in a timely and organized fashion. 
  • Prepare and review documents including experimental methods, batch records, SOPs, and reports. 
  • Maintain detailed laboratory notebook. 
  • Adhere to Phosphorex's Environmental Health and Safety practices and SOPs to maintain a safe, clean, and organized work environment free of safety hazards.  

Requirements

Qualifications and Education Requirements

  • Bachelor's degree in chemistry, pharmacy, pharmaceutical sciences, engineering, or other relevant discipline with 0-2 years relevant experience  
  • Strong analytical and critical thinking abilities 
  • Excellent organizational skills, attention to detail and ability to manage multiple priorities in a fast-paced and dynamic environment. 
  • Excellent verbal and written communication skills and ability to collaborate effectively with scientists and engineers working in other disciplines. 
  • Ability to work independently as well as with an interdisciplinary team in a highly collaborative environment. 
  • Demonstrated ability to contribute to multiple projects in parallel. 
  • Well versed with Microsoft Office applications. 

Preferred Skills

  • Prior experience with microfluidic fabrication of Lipid Nanoparticles (LNPs) and/or characterization of LNPs. 
  • Prior experience with biodegradable polymeric systems and development of micro-and nano-particle formulations.  
  • Experience in CDMO environment.  

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