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Associate Downstream Process Development Scientist Jobs in Worcester, MA

AbbVie

Global Process Engineer - Biologics

Worcester, MA · On-site

$124K/yr

The Global Biologics upstream and downstream Process Engineer will support the AbbVie Technical ... The selected candidate will contribute to the development of new principles and concepts and is ...

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All JobsAssociate Downstream Process Development Scientist JobsAssociate Downstream Process Development Scientist Jobs in Worcester, MA

Associate Downstream Process Development Scientist information

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$18

$33

$49

How much do associate downstream process development scientist jobs pay per hour?

As of Jul 19, 2026, the average hourly pay for associate downstream process development scientist in Worcester, MA is $33.61, according to ZipRecruiter salary data. Most workers in this role earn between $27.60 and $41.25 per hour, depending on experience, location, and employer.

What is an Associate Downstream Process Development Scientist?

An Associate Downstream Process Development Scientist is a professional who works in the biotechnology or pharmaceutical industry, focusing on developing and optimizing processes that purify biological products, such as proteins or antibodies, after they have been produced by cells. Their work is crucial for ensuring the final product meets quality and safety standards before it is used in research or clinical applications. They typically perform laboratory experiments, analyze data, and collaborate with other scientists and engineers to improve yield and efficiency. This role is often entry-level or early-career, providing hands-on experience in process development and technical troubleshooting.

What are the key skills and qualifications needed to thrive as an Associate Downstream Process Development Scientist, and why are they important?

To excel as an Associate Downstream Process Development Scientist, you need a solid understanding of biochemistry, chemical engineering, and downstream purification techniques, often supported by a bachelor's or master's degree in a life science or engineering discipline. Familiarity with chromatographic systems (such as AKTA), filtration equipment, and analytical tools, as well as knowledge of GMP/GLP regulations, is typically required. Strong problem-solving, attention to detail, and effective teamwork and communication skills help you navigate complex experiments and collaborate with cross-functional teams. These skills ensure efficient process optimization, compliance with regulatory standards, and successful development of biopharmaceutical products.

What is the difference between Associate Downstream Process Development Scientist vs Associate Upstream Process Development Scientist?

AspectAssociate Downstream Process Development ScientistAssociate Upstream Process Development Scientist
Primary FocusPurification and recovery of bioproductsCell culture and fermentation processes
Required SkillsProtein purification, chromatography, filtrationCell culture, bioreactor operation, media preparation
Work EnvironmentLaboratories, manufacturing facilitiesLaboratories, bioreactor labs
Common CertificationsBiotech or bioprocessing certificationsBiotech or bioprocessing certifications

Both roles are essential in biopharmaceutical development, focusing on different stages of the production process. The Associate Downstream Process Development Scientist specializes in purification techniques, while the Associate Upstream Process Development Scientist concentrates on cell growth and fermentation. Understanding these distinctions helps candidates target their skills and career paths effectively.

What are some typical challenges faced by an Associate Downstream Process Development Scientist, and how can they be addressed?

Associate Downstream Process Development Scientists often encounter challenges such as optimizing purification processes, troubleshooting equipment performance, and ensuring batch-to-batch consistency. These challenges can be addressed by maintaining meticulous documentation, collaborating closely with upstream and analytical teams, and staying current with best practices in chromatography and filtration. Proactively seeking feedback from experienced colleagues and participating in cross-functional meetings can also help in identifying solutions and improving process efficiency.
What are the most commonly searched types of Downstream Process Development Scientist jobs in Worcester, MA? The most popular types of Downstream Process Development Scientist jobs in Worcester, MA are:
What cities near Worcester, MA are hiring for Associate Downstream Process Development Scientist jobs? Cities near Worcester, MA with the most Associate Downstream Process Development Scientist job openings:
Associate Downstream Process Development Scientist jobs near you
Clinical Development Scientist

Clinical Development Scientist

Viridian Therapeutics, Inc.

Waltham, MA • On-site

$127K - $155K/yr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Re-posted 13 days ago

Job description

Description
At Viridian Therapeutics, we are focused on developing best-in-class medicines for people living with autoimmune and rare diseases. Leveraging our team's expertise in antibody discovery and engineering, we have created a robust pipeline of differentiated investigational therapeutic candidates for well-validated targets.
Reporting to the VP of Clinical Development, the Clinical Development Scientist will support all aspects of clinical development (safety, science, and operations), including the safety and pharmacovigilance team and trial activities. Additionally, the Clinical Development Scientist will author and review key trial data-related documents and be responsible for the life cycle management of these documents.
This role may be based in Waltham, MA, which would be a hybrid role, or it can also be fully remote. Our office-based employees are required to work in the office three (3) days a week. If remote, travel to headquarters for meetings would be required at the discretion of management.
Responsibilities (including, but not limited to):
  • Contribute to the development of clinical trial strategies and study design and work with the VP of Clinical Development in study protocol development, Investigator's Brochure updates, procedure manual development, Clinical Study Report development and scientific strategy
  • Support the VP of Clinical Development in collaborating with clinical leadership and cross-functional study teams to plan and execute clinical trials, with scientific integrity, from protocol concept through the clinical study report
  • Collaborate closely with Clinical Operations colleagues on clinical trial activities and timelines, including Informed consent development and review, data management activities and review of data management plans and other documents, and management of clinical development document deliverables to meet the operational needs of the program
  • Support Clinical Development in the activities associated with execution of clinical trials and data collection, including training of the internal team, vendors, and site staff; preparation of case report forms; identification and prevention of protocol deviations; and resolution of issues
  • Collaborate closely with Safety/Pharmacovigilance colleagues on clinical trial activities and timelines, including monitoring data to characterize safety information, in collaboration with the Medical Monitor and management of safety communications with clinical investigators
  • Contribute to overall clinical data review including data listings review to detect data trends and ensure data quality and coordinate these activities with cross-functional teams and engaged vendors
  • Responsible for the management of Data Safety Monitoring Board (DSMB) activities including collection of required qualification documents, development of DSMB Charters, coordinating DSMB meetings (scheduling, preparing materials and meeting minute responsibilities)
  • Support the interface with preclinical research and clinical development in the evaluation of scientific communication opportunities and management of the review and submission process
  • Partner with Viridian safety/PV and regulatory and the safety management vendor for worldwide safety reporting
  • Contribute to the preparation of clinical sections of regulatory documents (INDs); prepare for meetings with FDA/EMA
  • Stay current with GCP and worldwide regulatory requirements

Qualifications:
  • Requires a Bachelor's degree in Life Sciences and 5+ years' experience or Master's degree with 4+ years' experience or PhD with 2+ years' experience (or commensurate with other relevant Life Sciences degree)
  • Requires relevant experience in the biotechnology or pharmaceutical industry
  • Clinical experience across all phases of therapeutic development for multiple indications, with 2+ years in Clinical Development
  • Therapeutic area experience in Ophthalmology is strongly preferred; experience in Immunology or Neurology is a plus
  • Proven success record in the execution of clinical development strategies, as well as the successful submission of IND's
  • Experience authoring clinical documents eg, clinical protocols/ synopses, Investigator Brochures'; conducting literature reviews
  • Experience supporting drug safety and pharmacovigilance activities
  • Thorough knowledge of FDA regulatory requirements, clinical research concepts & practices, and ICH/GCP guidelines
  • Experience working with and managing third party vendors, such as CRO's
  • Proven ability for strategic thinking, creative problem-solving, and risk identification & mitigation skills
  • Team-oriented and works collaboratively as a team
  • Demonstrated strong written and verbal communication skills
  • Proven mindset of proactive continuous improvement
  • Efficient independent worker with ability to focus and drive for results
  • Strong attention to detail
  • Ability to work in a fast paced-environment and to handle multiple tasks
  • Strong commitment to ethical standards
  • Proficient with Microsoft Office suite (i.e., Word, PowerPoint, Excel, Outlook, SharePoint, etc.)
  • Ability to travel up to 10-20% domestic and internationally
  • The salary range for this position is commensurate with experience

Viridian offers a comprehensive benefits package including:
  • Competitive pay and stock options for all employees
  • Medical, dental, and vision insurance
  • 100% Paid Parental Leave
  • Short- and long-term disability coverage
  • Life, Travel and AD&D
  • 401(k) Company Match with immediate company vest
  • Employee Stock Purchase plan
  • Generous vacation plan and paid company holiday shutdowns
  • Various fertility, mental, financial, and proactive physical health programs

Viridian Therapeutics, Inc. provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination, harassment, or retaliation of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by Federal, State, and Local laws. Viridian will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
Viridian Therapeutics, Inc participates in E-Verify, the federal program for electronic verification of employment eligibility.

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