ZipRecruiter

Log In

1

Associate Downstream Process Development Scientist Jobs in California

next page

Showing results 1-20

All JobsAssociate Downstream Process Development Scientist JobsAssociate Downstream Process Development Scientist Jobs in California

Associate Downstream Process Development Scientist information

What is an Associate Downstream Process Development Scientist?

An Associate Downstream Process Development Scientist is a professional who works in the biotechnology or pharmaceutical industry, focusing on developing and optimizing processes that purify biological products, such as proteins or antibodies, after they have been produced by cells. Their work is crucial for ensuring the final product meets quality and safety standards before it is used in research or clinical applications. They typically perform laboratory experiments, analyze data, and collaborate with other scientists and engineers to improve yield and efficiency. This role is often entry-level or early-career, providing hands-on experience in process development and technical troubleshooting.

What are the key skills and qualifications needed to thrive as an Associate Downstream Process Development Scientist, and why are they important?

To excel as an Associate Downstream Process Development Scientist, you need a solid understanding of biochemistry, chemical engineering, and downstream purification techniques, often supported by a bachelor's or master's degree in a life science or engineering discipline. Familiarity with chromatographic systems (such as AKTA), filtration equipment, and analytical tools, as well as knowledge of GMP/GLP regulations, is typically required. Strong problem-solving, attention to detail, and effective teamwork and communication skills help you navigate complex experiments and collaborate with cross-functional teams. These skills ensure efficient process optimization, compliance with regulatory standards, and successful development of biopharmaceutical products.

What is the difference between Associate Downstream Process Development Scientist vs Associate Upstream Process Development Scientist?

AspectAssociate Downstream Process Development ScientistAssociate Upstream Process Development Scientist
Primary FocusPurification and recovery of bioproductsCell culture and fermentation processes
Required SkillsProtein purification, chromatography, filtrationCell culture, bioreactor operation, media preparation
Work EnvironmentLaboratories, manufacturing facilitiesLaboratories, bioreactor labs
Common CertificationsBiotech or bioprocessing certificationsBiotech or bioprocessing certifications

Both roles are essential in biopharmaceutical development, focusing on different stages of the production process. The Associate Downstream Process Development Scientist specializes in purification techniques, while the Associate Upstream Process Development Scientist concentrates on cell growth and fermentation. Understanding these distinctions helps candidates target their skills and career paths effectively.

What are some typical challenges faced by an Associate Downstream Process Development Scientist, and how can they be addressed?

Associate Downstream Process Development Scientists often encounter challenges such as optimizing purification processes, troubleshooting equipment performance, and ensuring batch-to-batch consistency. These challenges can be addressed by maintaining meticulous documentation, collaborating closely with upstream and analytical teams, and staying current with best practices in chromatography and filtration. Proactively seeking feedback from experienced colleagues and participating in cross-functional meetings can also help in identifying solutions and improving process efficiency.
What are the most commonly searched types of Downstream Process Development Scientist jobs in California? The most popular types of Downstream Process Development Scientist jobs in California are:
What cities in California are hiring for Associate Downstream Process Development Scientist jobs? Cities in California with the most Associate Downstream Process Development Scientist job openings:
Associate Downstream Process Development Scientist jobs near you

Scientist II, Downstream Viral Vector Process Development

GeneFab

Alameda, CA • On-site

$130K - $150K/yr

Full-time

Posted 10 days ago

Job description

GeneFab is seeking an experienced Downstream Process Development Scientist/Lead focused on viral vector purification (AAV and Lentiviral) for in vivo gene therapy. It is a technical, project-based role within a CRDMO environment that balances hands-on process optimization with cross-functional leadership and client-facing responsibilities.
Responsibilities
  • Design, optimize, and scale-up downstream processes for the purification of viral
    vectors, with a focus on in vivo gene therapy products and lentiviral vectors.
  • Execute experimental plans, analyze data, and provide insightful
    recommendations to improve process efficiency, yield, and product quality.
  • Collaborate with cross-functional teams, including Upstream Process
    Development, Analytical Development, and Manufacturing, to ensure seamless
    integration of processes.
  • Troubleshoot and resolve technical challenges in downstream processes, ensuring
    robust and scalable solutions.
  • Present internally and to client with project status updates
  • Stay abreast of industry trends, emerging technologies, and regulatory guidelines
    to contribute to the continuous improvement of processes and compliance.
  • Provide direction and leadership to development associates as the team expands.

Qualifications
  • Ph.D. or Master's degree in Chemical Engineering, Biochemical Engineering,
    Biotechnology, or related field with a minimum of 3 years (Ph.D.) or 5 years
    (Master's) of relevant industry experience
  • Proven expertise in downstream process development for viral vectors, with a
    focus on AAV and lentiviral vectors.
  • Hands-on experience with chromatography, filtration, TFF and other downstream
    processing techniques.
  • Strong analytical and problem-solving skills, with the ability to interpret complex
    data sets.
  • Excellent communication skills and the ability to work collaboratively in a team
    environment.
  • Knowledge of regulatory requirements and quality standards related to
    biopharmaceutical manufacturing.
  • Experience with formulation science preferred

$130,000 - $150,000 a year
About GeneFab
GeneFab is a contract manufacturing and synthetic biology biofoundry focused on cell and gene therapies. GeneFab was formed in 2023 with a vision to combine industry leading expertise in synthetic biology with advanced cGMP capabilities in order to accelerate the development and commercialization of genetic medicines. GeneFab offers its customers an extensive technology platform and know-how that spans early stage product design, technical development, and cGMP compliant production. GeneFab's technology platform includes bioinformatic-guided discovery of cell type promoters, directed evolution of small molecule-regulated gene switches, and the engineering of highly sensitive kill switches for enhanced safety and control of cellular therapies.
We are committed to an inclusive and diverse GeneFab. We believe that different perspectives lead to better ideas, and better ideas allow us to better understand the needs and interests of our diverse GeneFab team. We welcome people of different backgrounds, experiences, abilities, and perspectives and are an equal opportunity employer.
We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses and identifying potential inconsistencies or verification signals in application materials based on available information. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.

Apply