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Associate Downstream Process Development Scientist Jobs in California

Gilead

Sr Scientist, Process Development

Foster City, CA · On-site

$106K - $145K/yr

... development of life-changing scientific innovations. Our employees are our greatest asset as we ... Strong foundation in protein purification, chromatography mechanisms, and downstream process ...

Gilead

Scientist, Process Development

Foster City, CA · On-site

$146K - $189K/yr

Scientist, Purification Process Development - Pre-Pivotal Biologics - Foster City, CA The Scientist, Purification Process Development (Pre-Pivotal) will lead and execute purification process ...

Skyline DX USA Inc

Development Scientist

San Diego, CA · On-site

$80K - $120K/yr

SkylineDx USA is seeking a Development Scientist to support process development and assay support activities for our CLIA‑certified laboratory. This role plays a key part in assay development ...

LGC Group

Senior Scientist I, Process Development

Petaluma, CA · On-site

$104K - $142K/yr

The Senior Scientist in LGC Axolabs Process Development will serve as a subject matter expert (SME ... downstream processing steps in preparation for handover to routine manufacturing. This role ...

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All JobsAssociate Downstream Process Development Scientist JobsAssociate Downstream Process Development Scientist Jobs in California

Associate Downstream Process Development Scientist information

What is an Associate Downstream Process Development Scientist?

An Associate Downstream Process Development Scientist is a professional who works in the biotechnology or pharmaceutical industry, focusing on developing and optimizing processes that purify biological products, such as proteins or antibodies, after they have been produced by cells. Their work is crucial for ensuring the final product meets quality and safety standards before it is used in research or clinical applications. They typically perform laboratory experiments, analyze data, and collaborate with other scientists and engineers to improve yield and efficiency. This role is often entry-level or early-career, providing hands-on experience in process development and technical troubleshooting.

What are the key skills and qualifications needed to thrive as an Associate Downstream Process Development Scientist, and why are they important?

To excel as an Associate Downstream Process Development Scientist, you need a solid understanding of biochemistry, chemical engineering, and downstream purification techniques, often supported by a bachelor's or master's degree in a life science or engineering discipline. Familiarity with chromatographic systems (such as AKTA), filtration equipment, and analytical tools, as well as knowledge of GMP/GLP regulations, is typically required. Strong problem-solving, attention to detail, and effective teamwork and communication skills help you navigate complex experiments and collaborate with cross-functional teams. These skills ensure efficient process optimization, compliance with regulatory standards, and successful development of biopharmaceutical products.

What is the difference between Associate Downstream Process Development Scientist vs Associate Upstream Process Development Scientist?

AspectAssociate Downstream Process Development ScientistAssociate Upstream Process Development Scientist
Primary FocusPurification and recovery of bioproductsCell culture and fermentation processes
Required SkillsProtein purification, chromatography, filtrationCell culture, bioreactor operation, media preparation
Work EnvironmentLaboratories, manufacturing facilitiesLaboratories, bioreactor labs
Common CertificationsBiotech or bioprocessing certificationsBiotech or bioprocessing certifications

Both roles are essential in biopharmaceutical development, focusing on different stages of the production process. The Associate Downstream Process Development Scientist specializes in purification techniques, while the Associate Upstream Process Development Scientist concentrates on cell growth and fermentation. Understanding these distinctions helps candidates target their skills and career paths effectively.

What are some typical challenges faced by an Associate Downstream Process Development Scientist, and how can they be addressed?

Associate Downstream Process Development Scientists often encounter challenges such as optimizing purification processes, troubleshooting equipment performance, and ensuring batch-to-batch consistency. These challenges can be addressed by maintaining meticulous documentation, collaborating closely with upstream and analytical teams, and staying current with best practices in chromatography and filtration. Proactively seeking feedback from experienced colleagues and participating in cross-functional meetings can also help in identifying solutions and improving process efficiency.
What are the most commonly searched types of Downstream Process Development Scientist jobs in California? The most popular types of Downstream Process Development Scientist jobs in California are:
What cities in California are hiring for Associate Downstream Process Development Scientist jobs? Cities in California with the most Associate Downstream Process Development Scientist job openings:
Associate Downstream Process Development Scientist jobs near you
Scientist, Cell Line Development

Scientist, Cell Line Development

Avid Bioservices

Costa Mesa, CA

$85K - $116K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 22 days ago

Job description

Looking to join a passionate team dedicated to developing and manufacturing life-saving biopharmaceuticals? Avid Bioservices is a leading clinical and commercial biologics CDMO focused on creating innovative solutions to meet the needs of our clients and improve patient outcomes.
Your Role:
As a Cell Line Development Scientist, you will play a critical role in establishing high-performing mammalian cell lines that enable early-phase biologics programs. This position offers the opportunity to shape foundational capabilities in a fast-paced, collaborative environment focused on innovation and client success.
  • Design and execute strategies for stable cell line development using CHO cell line systems.
  • Perform hands-on CHO cell line development and characterization studies, including transfection, selection, single cell subcloning, growth and productivity screening, cell banking and stability assessment of cell banks.
  • Culture mammalian cells across multiple scales and formats, from 96-well plates up to large shake flasks, experience with ambr 250 and bioreactors is ideal.
  • Implement high-throughput screening and automation tools for clone evaluation.
  • Maintain rigorous documentation and ensure compliance with quality and regulatory standards.
  • Author and review cell line development reports, summaries, and presentations.
  • Present updates at client and cross-functional meetings.
  • Partner with Upstream and Downstream Process Development and Analytical teams to deliver integrated solutions.
  • Contribute to technology evaluations and continuous improvement initiatives for cell line workflows.
Minimum Qualifications:
  • M.S. in Cell Biology, Molecular Biology, Biochemistry, or related field.
  • 2-5 years of industry experience in cell development for biologics.
  • Hands-on experience with CHO cell systems, transfection methods, and clone screening for production of monoclonal antibodies, antibody-like molecules, enzymes, cytokines, bi-specifics and other recombinant molecules.
  • Strong knowledge of mammalian cell culture, molecular biology techniques and bio process engineering concepts.
  • Proficient in aseptic mammalian cell culture techniques.
  • Familiarity with automation platforms and data analysis tools.
  • Excellent problem-solving and communication skills.

Preferred Qualifications:

  • Knowledge of regulatory requirements for GMP manufacturing.
  • Exposure to high-throughput analytics and bioinformatics tools.
Position Type/Expected Hours of Work:
This role is a full-time position. Days of work are Monday through Friday. The employee must also, if instructed, have the ability to work overtime and/or weekends when necessary.
Compensation:
We offer competitive compensation packages for this role, including a base salary, performance-based bonuses, and comprehensive benefits such as health, dental, and vision insurance, 401(k) matching, and paid time off.
The compensation range for this role is $85,000 to $116,000 annually depending on experience and qualifications. Additionally, we offer opportunities for career growth and development as well as a supportive and inclusive work environment.
Who you are:
  • You have a "bring it on!" team player approach and an unshakable positive attitude, always ready to tackle anything that comes your way.
  • Your written and verbal skills are out of this world, and you communicate with clarity and confidence.
  • You have exceptional multitasking skills and an unparalleled attention to detail that ensure the smooth running of everything.
  • You are a master at building relationships, capable of establishing connections with anyone, be it team members, clients, vendors, or suppliers.
Physical Demands & Work Environment:
In this dynamic role, expect a blend of regular activities like sitting, standing, and walking, with occasional physically engaging tasks such as lifting objects up to 20 pounds. The work environment might expose you to electrical shocks, toxic chemicals, vibrations, or loud noise levels occasionally. However, reasonable accommodations are available to enable individuals with different abilities to perform effectively, ensuring a supportive and adaptable work setting. Your visual acuity, including close, distance, and color vision, will be essential in navigating through the diverse day-to-day demands of this position.
Employment Type: Full-Time

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