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Associate Downstream Process Development Scientist Jobs

Rocket Pharmaceuticals

NJ · On-site

$118 - $158/hr

Reporting to the Associate Director of the Downstream Process Development, the Senior Scientist will support gene therapy viral vector process development programs with a focus on downstream ...

Cascade Bio

Process Development Scientist

Denver, CO

$110K - $150K/yr

Process Development Scientist Location: Denver, CO (on-site) Type: Full-time Cascade Biocatalysts ... E-factor, PMI, catalyst cost contribution, and downstream processing implications * Interface with ...

Cascade Bio

Process Development Scientist

Denver, CO · On-site

$110K - $150K/yr

Process Development Scientist Location: Denver, CO (on-site) Type: Full-time Cascade Biocatalysts ... E-factor, PMI, catalyst cost contribution, and downstream processing implications * Interface with ...

Viltis

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Staff Engineer, Downstream Process Development & Manufacturing

San Carlos, CA · On-site

$186K - $218K/yr

Associate Director, MSAT - Protein Process Development and Manufacturing, Downstream The ... The company values scientific creativity, ambitious thinking, inclusive collaboration ...

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How much do associate downstream process development scientist jobs pay per hour?

As of Aug 22, 2026, the average hourly pay for associate downstream process development scientist in the United States is $33.68, according to ZipRecruiter salary data. Most workers in this role earn between $27.64 and $41.35 per hour, depending on experience, location, and employer.

What is an associate downstream process development scientist?

An Associate Downstream Process Development Scientist is a professional who works in the biotechnology or pharmaceutical industry, focusing on developing and optimizing processes that purify biological products, such as proteins or antibodies, after they have been produced by cells. Their work is crucial for ensuring the final product meets quality and safety standards before it is used in research or clinical applications. They typically perform laboratory experiments, analyze data, and collaborate with other scientists and engineers to improve yield and efficiency. This role is often entry-level or early-career, providing hands-on experience in process development and technical troubleshooting.

What are some typical challenges faced by an associate downstream process development scientist, and how can they be addressed?

Associate Downstream Process Development Scientists often encounter challenges such as optimizing purification processes, troubleshooting equipment performance, and ensuring batch-to-batch consistency. These challenges can be addressed by maintaining meticulous documentation, collaborating closely with upstream and analytical teams, and staying current with best practices in chromatography and filtration. Proactively seeking feedback from experienced colleagues and participating in cross-functional meetings can also help in identifying solutions and improving process efficiency.

What are the key skills and qualifications needed to thrive as an associate downstream process development scientist, and why are they important?

To excel as an Associate Downstream Process Development Scientist, you need a solid understanding of biochemistry, chemical engineering, and downstream purification techniques, often supported by a bachelor's or master's degree in a life science or engineering discipline. Familiarity with chromatographic systems (such as AKTA), filtration equipment, and analytical tools, as well as knowledge of GMP/GLP regulations, is typically required. Strong problem-solving, attention to detail, and effective teamwork and communication skills help you navigate complex experiments and collaborate with cross-functional teams. These skills ensure efficient process optimization, compliance with regulatory standards, and successful development of biopharmaceutical products.

What is the difference between Associate Downstream Process Development Scientist vs Associate Upstream Process Development Scientist?

AspectAssociate Downstream Process Development ScientistAssociate Upstream Process Development Scientist
Primary FocusPurification and recovery of bioproductsCell culture and fermentation processes
Required SkillsProtein purification, chromatography, filtrationCell culture, bioreactor operation, media preparation
Work EnvironmentLaboratories, manufacturing facilitiesLaboratories, bioreactor labs
Common CertificationsBiotech or bioprocessing certificationsBiotech or bioprocessing certifications

Both roles are essential in biopharmaceutical development, focusing on different stages of the production process. The Associate Downstream Process Development Scientist specializes in purification techniques, while the Associate Upstream Process Development Scientist concentrates on cell growth and fermentation. Understanding these distinctions helps candidates target their skills and career paths effectively.

What cities are hiring for Associate Downstream Process Development Scientist jobs?

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What are the most commonly searched types of Downstream Process Development Scientist jobs?

The most popular types of Downstream Process Development Scientist jobs are:

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Associate Downstream Process Development Scientist jobs near you

Sr. Research Associate, Process Development Downstream

Avid Bioservices

Tustin, CA • On-site

$72K - $91K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Re-posted 8 hours ago

Job description

Description
Looking to join a passionate team dedicated to developing and manufacturing life-saving biopharmaceuticals? Avid Bioservices is a leading clinical and commercial biologics CDMO focused on creating innovative solutions to meet the needs of our clients and improve patient outcomes.
Your Role:
The Senior Research Associate, Process Development Downstream will provide laboratory support for Process Development by leading in the downstream process and/or method development. The Senior Research Associate may be assigned various tasks within the department and outside the department as needed.
Key Responsibilities:
  • Serve as a subject matter expert (SME) and/or technical lead for downstream process development and purification of monoclonal antibodies, recombinant proteins, and related biologics. Responsibilities include buffer formulation and preparation, chromatography process development and optimization, filtration development, and routine process execution.
  • Lead downstream process development studies, including chromatography screening, process optimization, and scale-up activities to support client programs from early development through commercialization.
  • Perform and oversee in-process and routine analytical testing to support downstream development activities, including protein concentration determination (A280), HPLC-based assays, and other relevant analytical methods.
  • Independently execute downstream unit operations using chromatography systems, filtration equipment, and associated process analytical tools with minimal supervision.
  • Support process scale-up, technology transfer, and manufacturing operations by developing robust buffer preparation strategies and downstream processing workflows suitable for pilot and GMP manufacturing environments.
  • Compile, analyze, interpret, and present experimental data. Author technical reports, development summaries, protocols, and client-facing documentation, and present findings during internal project reviews and client meetings.
  • Lead troubleshooting and continuous improvement initiatives to enhance process performance, robustness, productivity, and scalability.
  • Contribute to the evaluation, implementation, and validation of emerging technologies, process analytics, laboratory automation platforms, and process intensification strategies to improve development efficiency.
  • Experience with laboratory automation, process intensification, process analytical technologies (PAT), high-throughput process development, and data analytics is highly desirable.
  • Mentor junior scientists and provide technical guidance across downstream process development activities.
  • Perform other duties and project-related responsibilities as assigned.

Minimum Qualifications:
  • Bachelor's degree with 3-4 years of relevant biopharmaceutical industry experience, or a Master's degree in Chemical Engineering, Biochemical Engineering, Biotechnology, Biological Sciences, or a related field.
  • Candidates should possess a strong understanding of downstream processing principles, experimental design, data analysis, and bioprocess development methodologies.

Position Type/Expected Hours of Work:
This role is a full-time onsite position. Days and hours of work are Monday through Friday unless otherwise stated by Supervisor. The employee must also have the ability to work overtime and/or weekends when necessary.
Compensation:
We offer competitive compensation packages for this role, including a base salary, performance-based bonuses, and comprehensive benefits such as health, dental, and vision insurance, 401(k) matching, and paid time off.
The compensation range for this role is $72,800 - $91,000 annually depending on experience and qualifications. Additionally, we offer opportunities for career growth and development as well as a supportive and inclusive work environment.
Who you are:
  • You have a "bring it on!" team player approach and an unshakable positive attitude, always ready to tackle anything that comes your way.
  • Your written and verbal skills are out of this world, and you communicate with clarity and confidence.
  • You have exceptional multitasking skills and an unparalleled attention to detail that ensure the smooth running of everything.
  • You are a master at building relationships, capable of establishing connections with anyone, be it team members, clients, vendors, or suppliers.

Physical Demands & Work Environment:
In this dynamic role, expect a blend of regular activities like sitting, standing, and walking, with occasional physically engaging tasks such as lifting objects up to 25 pounds. The work environment might expose you to electrical shocks, toxic chemicals, vibrations, or loud noise levels occasionally. However, reasonable accommodations are available to enable individuals with different abilities to perform effectively, ensuring a supportive and adaptable work setting. Your visual acuity, including close, distance, and color vision, will be essential in navigating through the diverse day-to-day demands of this position.

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