The successful candidate will define and drive the scientific vision for leveraging PDOs to validate hypotheses generated from Tempus' unique real-world clinico-genomic data assets. Working closely ...

60 Tempus Data Scientist Jobs Hiring Near You
The successful candidate will define and drive the scientific vision for leveraging PDOs to validate hypotheses generated from Tempus' unique real-world clinico-genomic data assets. Working closely ...
Translational Scientist, Applied Machine Learning and Agentic AI, Pharma R&D Location: New York, NY ... Description Data Expertise: Tempus has one of the largest multimodal patient datasets ever ...
Translational Scientist, Applied Machine Learning and Agentic AI, Pharma R&D Location: New York, NY ... Description Data Expertise: Tempus has one of the largest multimodal patient datasets ever ...
Translational Scientist, Applied Machine Learning and Agentic AI, Pharma R&D Location: New York, NY ... Description Data Expertise: Tempus has one of the largest multimodal patient datasets ever ...
Translational Scientist, Applied Machine Learning and Agentic AI, Pharma R&D Location: New York, NY ... Description Data Expertise: Tempus has one of the largest multimodal patient datasets ever ...
Translational Scientist, Applied Machine Learning and Agentic AI, Pharma R&D Location: New York, NY ... Description Data Expertise: Tempus has one of the largest multimodal patient datasets ever ...
Translational Scientist, Applied Machine Learning and Agentic AI, Pharma R&D Location: New York, NY ... Description Data Expertise: Tempus has one of the largest multimodal patient datasets ever ...
Translational Scientist, Applied Machine Learning and Agentic AI, Pharma R&D
Redwood City, CA · On-site
Translational Scientist, Applied Machine Learning and Agentic AI, Pharma R&D Location: New York, NY ... Description Data Expertise: Tempus has one of the largest multimodal patient datasets ever ...
Translational Scientist, Applied Machine Learning and Agentic AI, Pharma R&D
Redwood City, CA · On-site
Translational Scientist, Applied Machine Learning and Agentic AI, Pharma R&D Location: New York, NY ... Description Data Expertise: Tempus has one of the largest multimodal patient datasets ever ...
Senior Technical Product Manager
Chicago, IL · On-site
$130K - $172K/yr
... scientists, engineers, ML/AI engineering teams, and designers to develop elegant software solutions. * Define and own product strategy for key areas of the Tempus Data Platform, with a focus on ...
Senior Technical Product Manager
Chicago, IL · On-site
$130K - $172K/yr
... scientists, engineers, ML/AI engineering teams, and designers to develop elegant software solutions. * Define and own product strategy for key areas of the Tempus Data Platform, with a focus on ...
Senior Software Engineer II, Data Products
Chicago, IL · On-site
$126K - $166K/yr
Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real ... Leverage your expertise to support cross-functional science, ML, and AI teams. You will act as a ...
Senior Software Engineer II, Data Products
Chicago, IL · On-site
$126K - $166K/yr
Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real ... Leverage your expertise to support cross-functional science, ML, and AI teams. You will act as a ...
Senior Software Engineer II, Data Products
Chicago, IL · On-site
$126K - $166K/yr
Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real ... Leverage your expertise to support cross-functional science, ML, and AI teams. You will act as a ...
Senior Software Engineer II, Data Products
Chicago, IL · On-site
$126K - $166K/yr
Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real ... Leverage your expertise to support cross-functional science, ML, and AI teams. You will act as a ...
Senior Technical Product Manager
Chicago, IL · On-site
$130K - $172K/yr
... scientists, engineers, ML/AI engineering teams, and designers to develop elegant software solutions. * Define and own product strategy for key areas of the Tempus Data Platform, with a focus on ...
Senior Technical Product Manager
Chicago, IL · On-site
$130K - $172K/yr
... scientists, engineers, ML/AI engineering teams, and designers to develop elegant software solutions. * Define and own product strategy for key areas of the Tempus Data Platform, with a focus on ...
Senior Technical Product Manager
Chicago, IL · On-site
$110 - $160/hr
... scientists, engineers, ML/AI engineering teams, and designers to develop elegant software solutions.* Define and own product strategy for key areas of the Tempus Data Platform, with a focus on secure ...
Senior Technical Product Manager
Chicago, IL · On-site
$110 - $160/hr
... scientists, engineers, ML/AI engineering teams, and designers to develop elegant software solutions.* Define and own product strategy for key areas of the Tempus Data Platform, with a focus on secure ...
Director, Strategy & Operations
Chicago, IL · On-site
$150K - $220K/yr
Tempus's Data & AI Partnerships business is scaling fast, and how we sell needs to scale with it ... Experience in life sciences, healthcare, health tech, or data-focused SaaS. * Direct experience ...
Director, Strategy & Operations
Chicago, IL · On-site
$150K - $220K/yr
Tempus's Data & AI Partnerships business is scaling fast, and how we sell needs to scale with it ... Experience in life sciences, healthcare, health tech, or data-focused SaaS. * Direct experience ...
Senior Data Modeler
Boston, MA · On-site
$120K - $170K/yr
At Tempus, products are owned and developed by small, autonomous teams composed of developers, designers, data scientists, clinicians, and product managers. You and your team set the goals, build the ...
Senior Data Modeler
Boston, MA · On-site
$120K - $170K/yr
At Tempus, products are owned and developed by small, autonomous teams composed of developers, designers, data scientists, clinicians, and product managers. You and your team set the goals, build the ...
Senior Data Modeler
Chicago, IL · On-site
$120K - $170K/yr
At Tempus, products are owned and developed by small, autonomous teams composed of developers, designers, data scientists, clinicians, and product managers. You and your team set the goals, build the ...
Senior Data Modeler
Chicago, IL · On-site
$120K - $170K/yr
At Tempus, products are owned and developed by small, autonomous teams composed of developers, designers, data scientists, clinicians, and product managers. You and your team set the goals, build the ...
Director, Strategy & Operations
Redwood City, CA · Hybrid
$150K - $220K/yr
Tempus's Data & AI Partnerships business is scaling fast, and how we sell needs to scale with it ... Experience in life sciences, healthcare, health tech, or data-focused SaaS. * Direct experience ...
Director, Strategy & Operations
Redwood City, CA · Hybrid
$150K - $220K/yr
Tempus's Data & AI Partnerships business is scaling fast, and how we sell needs to scale with it ... Experience in life sciences, healthcare, health tech, or data-focused SaaS. * Direct experience ...
Senior Data Modeler
Chicago, IL · On-site
$120K - $170K/yr
At Tempus, products are owned and developed by small, autonomous teams composed of developers, designers, data scientists, clinicians, and product managers. You and your team set the goals, build the ...
Senior Data Modeler
Chicago, IL · On-site
$120K - $170K/yr
At Tempus, products are owned and developed by small, autonomous teams composed of developers, designers, data scientists, clinicians, and product managers. You and your team set the goals, build the ...
Director, Strategy & Operations
Manhattan, NY · On-site
$150 - $220/hr
Tempus's Data & AI Partnerships business is scaling fast, and how we sell needs to scale with it ... Experience in life sciences, healthcare, health tech, or data-focused SaaS.* Direct experience ...
Director, Strategy & Operations
Manhattan, NY · On-site
$150 - $220/hr
Tempus's Data & AI Partnerships business is scaling fast, and how we sell needs to scale with it ... Experience in life sciences, healthcare, health tech, or data-focused SaaS.* Direct experience ...
Director, Strategy & Operations
Chicago, IL · Hybrid
$150K - $220K/yr
Tempus's Data & AI Partnerships business is scaling fast, and how we sell needs to scale with it ... Experience in life sciences, healthcare, health tech, or data-focused SaaS. * Direct experience ...
Director, Strategy & Operations
Chicago, IL · Hybrid
$150K - $220K/yr
Tempus's Data & AI Partnerships business is scaling fast, and how we sell needs to scale with it ... Experience in life sciences, healthcare, health tech, or data-focused SaaS. * Direct experience ...
Scientist II, Translational Research
Redwood City, CA · On-site
$100K - $150K/yr
Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real ... Data Science teams. • Work with Product and Engineering teams to streamline workflow of ...
Scientist II, Translational Research
Redwood City, CA · On-site
$100K - $150K/yr
Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real ... Data Science teams. • Work with Product and Engineering teams to streamline workflow of ...
Bioinformatics Scientist
Redwood City, CA · On-site
Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real ... Computational skills using Python and/or R, including experience with data science and biological ...
Bioinformatics Scientist
Redwood City, CA · On-site
Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real ... Computational skills using Python and/or R, including experience with data science and biological ...
Bioinformatics Scientist
Chicago, IL · On-site +1
Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real ... Computational skills using Python and/or R, including experience with data science and biological ...
Bioinformatics Scientist
Chicago, IL · On-site +1
Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real ... Computational skills using Python and/or R, including experience with data science and biological ...
Tempus Jobs Information
What is it like to work at Tempus?
The company's structure is designed to facilitate interdisciplinary collaboration, with teams comprising experts from various fields, including medicine, engineering, and data science, working together to develop and implement cutting-edge technologies that improve cancer care and patient outcomes.
Working at Tempus may appeal to individuals who are passionate about using data and technology to drive meaningful change in healthcare, as the company offers opportunities for professional growth, a dynamic work environment, and the chance to contribute to a mission that has the potential to impact millions of lives.
What makes Tempus an attractive place to work?
What other companies are hiring for Data Scientist jobs?
What are the most popular jobs at Tempus?
What are the most popular categories at Tempus?

Full-time
PTO
Posted 25 days ago
Job description
Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.
We are seeking an exceptional Senior Director, Functional Genomics & Organoid Systems Biology to lead and expand our patient-derived organoid (PDO) biology platform. This leader will drive the wet lab component of our systems biology team, and will help define how this experimental layer will combine with computational approaches and the massive multimodal Tempus data layer to unlock new biological insights. This leader will oversee a multidisciplinary team of scientists and research associates responsible for executing large-scale functional screens-including CRISPR-based genetic perturbation screens, drug sensitivity screens, single-cell and spatial technologies, and combination therapy studies-in clinically annotated patient-derived organoid models.
The successful candidate will define and drive the scientific vision for leveraging PDOs to validate hypotheses generated from Tempus' unique real-world clinico-genomic data assets. Working closely with computational scientists, machine learning researchers, translational scientists, and clinical teams, this individual will establish an integrated discovery engine that translates patient data into experimentally validated therapeutic opportunities.
This is a highly visible leadership role that combines scientific strategy, organizational leadership, platform development, and translational research to identify novel targets, biomarkers, and therapeutic strategies for cancer patients.
This position is based in Tempus' Chicago lab: hybrid or remote candidates will not be considered.
Key Responsibilities
- Define and execute the long-term scientific strategy for functional screening and target discovery using patient-derived organoid models.
- Establish a world-class organoid-based discovery platform capable of validating hypotheses generated from large-scale multimodal patient datasets.
- Serve as a scientific thought leader internally and externally, representing the company through publications, presentations, and strategic collaborations.
- Oversee the design, execution, and interpretation of large-scale CRISPR screening campaigns, including knockout, activation, interference, and pooled screening approaches.
- Lead drug screening efforts across diverse PDO models to identify therapeutic sensitivities, resistance mechanisms, and rational drug combinations.
- Drive development of next-generation functional assays incorporating co-culture systems, immune components, and emerging technologies.
- Establish rigorous experimental standards, quality systems, and reproducible workflows across the screening platform.
- Ensure efficient scaling of laboratory operations to support discovery and translational research objectives.
- Partner closely with computational biology and data science teams to prioritize hypotheses arising from real-world patient data.
- Create an iterative discovery framework in which computational predictions are experimentally tested and experimental findings inform subsequent computational analyses.
- Collaborate with clinical, molecular profiling, and translational research teams to connect experimental findings with patient outcomes and therapeutic hypotheses.
- Build, lead, and mentor a high-performing team of scientists, research associates, and laboratory personnel.
- Foster a culture of scientific excellence, innovation, accountability, and collaboration.
- Recruit top-tier talent across functional genomics, organoid biology, and translational oncology.
- Establish clear goals, development plans, and performance expectations for team members.
- Manage departmental budgets, resource allocation, and strategic planning.
Required Qualifications
- PhD, MD, or MD/PhD in Cancer Biology, Molecular Biology, Genetics, Functional Genomics, Bioengineering, or a related discipline.
- 8+ years of relevant industry and/or academic experience, including substantial leadership experience.
- Deep expertise in cancer biology, functional genomics, and target discovery.
- Demonstrated experience leading CRISPR-based screening programs and large-scale functional biology initiatives.
- Hands-on experience with patient-derived organoids, ex vivo models, or other clinically relevant disease model systems.
- Track record of translating biological insights into therapeutic hypotheses, biomarkers, or drug discovery programs.
- Experience managing and mentoring multidisciplinary scientific teams.
- Strong publication and/or patent record demonstrating scientific impact.
- Excellent communication skills and ability to influence across scientific and executive stakeholders.
CHI: $190,000 - $270,000
The expected salary range above is applicable if the role is performed from Illinois and may vary for other locations (California, Colorado, New York). Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position.
We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.