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Wolfram Jobs (NOW HIRING)

PsiQuantum

Photonics Circuit Designer

Palo Alto, CA · On-site

Experience using the Wolfram Language is a plus. PsiQuantum provides equal employment opportunity for all applicants and employees. PsiQuantum does not unlawfully discriminate on the basis of race ...

PsiQuantum

Photonics Circuit Designer

Palo Alto, CA

Experience using the Wolfram Language is a plus. PsiQuantum provides equal employment opportunity for all applicants and employees. PsiQuantum does not unlawfully discriminate on the basis of race ...

Ketryx

Legal Counsel

Boston, MA · On-site

$200K - $250K/yr

... of Wolfram Cloud. What starts in life sciences scales everywhere: automotive, aerospace, energy, any sector where safety is non-negotiable. The Role Be Ketryx's first in-house Legal Counsel ...

Ketryx

Enterprise Account Executive

Boston, MA

$225K - $300K/yr

Backed by Lightspeed Ventures, our founders are the former Head of AI at Amgen and CTO of Wolfram Cloud. Healthcare and life sciences is just the beginning for us. Automotive, aerospace, energy - if ...

Ketryx

Delivery and Success Manager (Boston)

Boston, MA · On-site

$90K - $115K/yr

Backed by Lightspeed Ventures, our founders are the former Head of AI at Amgen and CTO of Wolfram Cloud. Healthcare and life sciences is just the beginning for us. Automotive, aerospace, energy - if ...

Ketryx

Delivery and Success Manager (Boston)

Boston, MA · On-site

$90K - $115K/yr

Backed by Lightspeed Ventures, our founders are the former Head of AI at Amgen and CTO of Wolfram Cloud. Healthcare and life sciences is just the beginning for us. Automotive, aerospace, energy - if ...

Ketryx

Delivery and Success Manager (Boston)

Boston, MA

$90K - $115K/yr

Backed by Lightspeed Ventures, our founders are the former Head of AI at Amgen and CTO of Wolfram Cloud. Healthcare and life sciences is just the beginning for us. Automotive, aerospace, energy - if ...

Ketryx

Delivery and Success Manager (Boston)

Boston, MA · On-site

$90K - $115K/yr

Backed by Lightspeed Ventures, our founders are the former Head of AI at Amgen and CTO of Wolfram Cloud. Healthcare and life sciences is just the beginning for us. Automotive, aerospace, energy - if ...

Ketryx

Technical Product Marketing Manager

Boston, MA

$130K - $170K/yr

Backed by Lightspeed Ventures, our founders are the former Head of AI at Amgen and CTO of Wolfram Cloud. Healthcare and life sciences is just the beginning for us. Automotive, aerospace, energy - if ...

Ketryx

Software Engineer

Boston, MA · On-site

$130K - $150K/yr

Backed by Lightspeed Ventures, our founders are the former Head of AI at Amgen and CTO of Wolfram Cloud. Healthcare and life sciences is just the beginning for us. Automotive, aerospace, energy - if ...

Ketryx

Enterprise Account Executive

Boston, MA · On-site

$225K - $300K/yr

Backed by Lightspeed Ventures, our founders are the former Head of AI at Amgen and CTO of Wolfram Cloud. Healthcare and life sciences is just the beginning for us. Automotive, aerospace, energy - if ...

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As of Jun 9, 2026, the average hourly pay for wolfram in the United States is $26.34, according to ZipRecruiter salary data. Most workers in this role earn between $15.14 and $30.77 per hour, depending on experience, location, and employer.

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To thrive as a Wolfram Language Developer, you need strong skills in programming (especially in the Wolfram Language), computational thinking, and a background in mathematics or science. Familiarity with Wolfram Mathematica, Wolfram Alpha, and related cloud or notebook environments is typically required, along with optional certifications like Wolfram Certified Instructor. Creative problem-solving, attention to detail, and effective communication help you stand out in developing and deploying computational solutions. These abilities are essential for creating robust, efficient code and collaborating successfully on complex projects in technical environments.

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Wolfram jobs typically refer to positions at Wolfram Research, the company behind Mathematica and the Wolfram Alpha computational engine. These jobs can range from software engineering and research roles to positions in technical support, marketing, and sales, all focused on computational technology and knowledge-based programming. Employees often work on cutting-edge projects in computational mathematics, data science, artificial intelligence, and related fields. Working at Wolfram involves contributing to innovative products used by scientists, engineers, educators, and developers worldwide.

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A Wolfram job typically refers to a position at Wolfram Research, the company behind Mathematica and Wolfram Alpha, or a role involving Wolfram technologies. These jobs often require expertise in computational science, mathematics, or software development. Positions may include software engineering, data science, research, or technical support, often leveraging the Wolfram Language.

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Required CredentialsMathematics, Computer Science, or related degrees; programming skills in Wolfram LanguageStatistics, Mathematics, or related degrees; proficiency in data analysis tools like Excel, SQL, Python
Work EnvironmentResearch labs, software development, academic settingsBusiness, finance, healthcare, or tech industries; office environments
Industry UsageMathematical modeling, computational research, algorithm developmentData interpretation, reporting, business decision support

Wolfram professionals focus on computational research and mathematical modeling using Wolfram Language, often in research or development settings. Data Analysts interpret and visualize data to support business decisions, typically using tools like Excel or Python. While both roles require analytical skills, Wolfram roles emphasize programming and mathematical modeling, whereas Data Analysts focus on data interpretation and reporting.

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Infographic showing various Wolfram job openings in the United States as of May 2026, with employment types broken down into 86% Full Time, and 14% Part Time. Highlights an 100% In-person job distribution, with an average salary of $54,791 per year, or $26.3 per hour.
Associate Director, Computer System Validation & Quality Compliance

Associate Director, Computer System Validation & Quality Compliance

Amylyx Pharmaceuticals

Cambridge, MA • On-site

Full-time

Posted 2 days ago

Job description

Amylyx has an audacious mission to usher in a new era for treating diseases with high unmet needs. Where others see challenges, we see opportunities that we pursue with urgency, rigorous science, and unwavering commitment to the communities we serve. We are a clinical-stage company currently focused on post-bariatric hypoglycemia (PBH), Wolfram syndrome, and amyotrophic lateral sclerosis (ALS).
Our mission is powered by our people. Our core values - be audacious, be curious, be authentic, be engaged, and be accountable - creating a culture of caring. Amylyx has assembled an experienced team ready to take action because the communities we serve have no time to wait. If you share our passion and are determined to tackle some of medicine's toughest problems, we encourage you to read the opportunity below and apply.
The Opportunity
The Associate Director, Computer System Validation (CSV) & Quality Compliance provides enterprise-level leadership, strategic direction, and governance for the validation, lifecycle management, and continuous compliance of GxP-relevant computerized systems, with a strong emphasis on the Veeva Quality Suite. This role ensures that digital quality solutions and supporting systems meet global regulatory requirements (FDA, EMA, ICH, GAMP 5), maintain data integrity, and enable a sustainable, inspection-ready state across the organization.
This person will partner closely with Quality, IT, Regulatory, Clinical, and business process owners to define system requirements, lead new system implementations and major enhancements, and drive harmonized, risk-based validation practices. This role also oversees quality compliance processes such as Change Control, Deviations, CAPA, and continuous improvement, ensuring timely closure, trend analysis, and effective governance through leadership of key forums including Quality Management Review and cross-functional compliance meetings.
Responsibilities
Strategic Leadership & Governance
  • Develop, evolve, and steward the corporate CSV/CSA strategy, ensuring alignment with enterprise digital strategy and Quality Management System (QMS) objectives.
  • Serve as the senior Quality authority for computerized systems validation, data integrity, and electronic system compliance.
  • Oversee enterprise-wide governance programs, ensuring standardized, risk-based approaches to system implementation and maintenance.
  • Provide strategic guidance to senior leadership regarding system performance, risks, and compliance maturity.

Computer System Validation & Lifecycle Oversight
  • Lead planning, execution, review, and approval of validation deliverables across GxP systems.
  • Oversee system lifecycle activities including impact assessments, change management, periodic reviews, audit trails, user access reviews, and system retirement.
  • Promote and reinforce CSA-aligned, risk-based validation practices to streamline compliance and maximize efficiency.
  • Ensure documentation quality and consistent application of SDLC principles across projects.

Veeva Systems Expertise & Optimization
  • Serve as the Quality SME for the Veeva Quality Suite, providing expert guidance on configuration, workflow optimization, and release readiness.
  • Lead implementation, enhancement, and optimization of Veeva Vault modules and cross-functional integrations.
  • Drive automation and digitization initiatives that improve usability, compliance, and system performance.
  • Partner with IT and Veeva administrators to maintain robust, compliant change control processes.

Quality & Regulatory Compliance
  • Ensure all computerized systems maintain compliance with 21 CFR Part 11, EU Annex 11, GxP principles, and global data integrity expectations.
  • Author, revise, and own Quality System policies and procedures related to electronic systems and validation.
  • Represent Quality during internal audits, external regulatory inspections, and vendor assessments.
  • Lead timely remediation, effectiveness checks, and continuous improvement initiatives.
  • Provide oversight and trending for Quality Events related to system performance or compliance.

Required Qualifications
  • Bachelor's degree in a relevant scientific or technical discipline.
  • 8+ years of experience in the life sciences industry with strong GxP system experience.
  • Extensive leadership experience in cross functional implementation and validation of GxP computerized systems.
  • Deep expertise with Veeva Vault Quality Suite (QMS, Docs, Training, etc.).
  • Strong knowledge of global regulatory expectations and data integrity frameworks.
  • Demonstrated ability to lead enterprise programs, influence stakeholders, and drive compliant decision making.

Preferred Qualifications
  • Expertise with SaaS/cloud architectures and database compliance expectations.
  • Understanding of clinical data collection technologies and supporting data processes.
  • Familiarity with SDLC, Agile methodologies, CSV vs. CSA principles and automated testing platforms.
  • Experience developing and interpreting Quality metrics such as KPIs and KQIs.
  • Excellent communication skills with the ability to collaborate, negotiate, and influence at all organizational levels.

Work Location and Conditions
  • At Amylyx, we proudly support remote work opportunities within the United States. However, due to business considerations related to health insurance coverage and state tax regulations, we are unable to hire employees who reside and/or work in certain states. Currently, we are not considering applicants from Alaska, Arizona, Hawaii, Michigan and Tennessee.
  • You will be expected to travel to our corporate location in Cambridge, MA several times a year and attend other company-related events as necessary and requested, which may include travel by air, driving or public transportation.
  • You must have access to work in setting that meets all requirements of the role (including privacy, reliable internet access, phone, ability to communication via video conference, etc.) at your remote location.

Compensation
The pay range posted below represents our good faith estimate of compensation for this role, based on market data and internal benchmarks. The final offer may vary depending on a candidate's experience, skills, and qualifications, as well as considerations of internal equity.
Estimated Pay Range
$170,000-$191,000 USD
To stay connected with us, follow Amylyx Pharmaceuticals on LinkedIn.
To return to our website please click here.
Amylyx Pharmaceuticals is an Equal Opportunity Employer that does not discriminate on the basis of actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, pregnancy-related conditions, and lactation), gender identity or expression (including transgender status), sexual orientation, marital status, military service and veteran status, physical or mental disability, genetic information, or any other characteristic protected by applicable federal, state, or local laws and ordinances. Amylyx's management team is dedicated to this policy with respect to recruitment, hiring, placement, promotion, transfer, training, compensation, benefits, employee activities, access to facilities and programs, and general treatment during employment. Accommodations are available for candidates who require them in our selection process. If you need an accommodation, please let your Amylyx Talent Acquisition contact know.
It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

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