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Weekend Rn Jobs in Spartanburg, SC (NOW HIRING)

PACS

RN

Greenville, SC · On-site

$34 - $41/hr

Registered Nurse (RN) Patewood Post Acute - Greenville, SC $34-$41/hour + Shift Diff | Full-Time ... Competitive pay: $34-$41/hour * $3/hour weekend shift differential * Full-time 1st and 3rd shift ...

Magnolia Manor of Inman

Registered Nurse RN

Inman, SC · On-site

$35 - $37/hr

Why work at Magnolia Manor Inman as an RN- Registered Nurse? Now offering a $5,000.00 sign on bonus for newly hired, full time (7p-7a) RN. Newly hired full time (Nights) RN must start on or before ...

Magnolia Manor of Inman

Registered Nurse RN

Inman, SC · On-site

$35 - $37/hr

Job Highlights Why work at Magnolia Manor Inman as an RN- Registered Nurse? Now offering a $5,000.00 sign on bonus for newly hired, full time (7p-7a) RN. Newly hired full time (Nights) RN must start ...

Magnolia Manor of Inman

Registered Nurse RN

Inman, SC · On-site

$35 - $37/hr

Job Highlights Why work at Magnolia Manor Inman as an RN- Registered Nurse? Now offering a $5,000.00 sign on bonus for newly hired, full time (7p-7a) RN. Newly hired full time (Nights) RN must start ...

Magnolia Manor of Inman

Registered Nurse RN

Inman, SC · On-site

$35 - $37/hr

Job Highlights Why work at Magnolia Manor Inman as an RN- Registered Nurse? Now offering a $5,000.00 sign on bonus for newly hired, full time (7p-7a) RN. Newly hired full time (Nights) RN must start ...

NHC

RN Registered Nurse

Greenville, SC · On-site

Position: RN, Registered Nurse Licensure: South Carolina Registered Nurse, RN Nursing license Benefits we offer: Competitive PayEarned Time Off Health, Dental, Vision, Disability and Life insurance ...

Pacs

Registered Nurse (RN)

Greenville, SC · On-site

$51/hr

Now Hiring: Registered Nurse (RN) City View Post-Acute Compensation: $49- $51 per hour Full Time - NOC Shift Overview: City View Post-Acute is currently seeking a qualified and compassionate ...

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Showing results 21-40

All JobsRn JobsWeekend Rn JobsWeekend Rn Jobs in Spartanburg, SC

Weekend Rn information

See Spartanburg, SC salary details

$25

$40

$67

How much do weekend rn jobs pay per hour?

As of Aug 9, 2026, the average hourly pay for weekend rn in Spartanburg, SC is $40.40, according to ZipRecruiter salary data. Most workers in this role earn between $32.06 and $46.63 per hour, depending on experience, location, and employer.

What does a Weekend RN do?

As a weekend RN, you take shifts on the weekend when other nurses are unavailable, allowing hospitals and other care facilities to provide continuity of care and remain open 24/7. This is usually a part-time position, with most weekend RN's working two 8-12 hour shifts Saturday-Sunday each week. Some facilities also count Friday as a weekend day and offer a three-shift schedule instead. In this role, you may make patient visits, answer telephone calls to provide remote healthcare and address any medical emergencies that occur during your shift as a weekend nurse. As an RN, weekend work usually focuses on hospitals and hospice facilities, but you may find positions that involve traveling to visit patients outside of a clinical setting.

What are some unique challenges and rewards of working as a Weekend RN compared to a standard weekday nursing position?

Weekend RNs often face a distinct set of challenges, including managing higher patient-to-nurse ratios and handling more acute or urgent cases, as there may be fewer staff and support services available on weekends. However, this role also offers unique rewards, such as greater autonomy, opportunities to hone critical thinking and decision-making skills, and often a more flexible schedule or additional compensation. Weekend RNs typically collaborate closely with a dedicated core team, fostering strong teamwork and communication. This experience can be valuable for career advancement, as it demonstrates adaptability and strong clinical competence in a fast-paced environment.

What is the difference between Weekend Rn vs Weekend Lpn?

AspectWeekend RnWeekend Lpn
Required CredentialsRegistered Nurse license (RN)Licensed Practical Nurse license (LPN)
Work EnvironmentHospitals, clinics, long-term care facilitiesLong-term care, nursing homes, clinics
Employer & Industry UsageHospitals, healthcare agenciesLong-term care facilities, nursing homes
Common Search & Comparison IntentUnderstanding RN roles on weekendsUnderstanding LPN roles on weekends

Weekend Rn and Weekend Lpn roles differ mainly in credentials, with RNs holding a registered nurse license and LPNs holding a practical nurse license. RNs typically perform more complex medical tasks and have broader responsibilities, while LPNs focus on basic patient care. Both roles are common in healthcare settings that require weekend coverage, but RNs generally have more advanced training and scope of practice.

What is a Weekend RN?

A Weekend RN is a registered nurse who primarily works during the weekends, often covering shifts on Saturdays and Sundays. These nurses provide patient care, administer medications, monitor patient progress, and collaborate with doctors and other healthcare staff. Weekend RNs may work in hospitals, nursing homes, or other healthcare facilities, and their schedules are designed to ensure continuous high-quality care throughout the week. Weekend shifts can sometimes offer higher pay rates or shift differentials due to the non-traditional hours.

What are the key skills and qualifications needed to thrive as a Weekend RN, and why are they important?

To thrive as a Weekend RN, you need current RN licensure, strong clinical assessment skills, and experience in acute or long-term care settings. Familiarity with electronic health record (EHR) systems and up-to-date certifications such as BLS or ACLS are often required. Excellent time management, adaptability, and communication skills are essential for managing patient care during typically higher-acuity weekend shifts. These competencies ensure patient safety, efficient care delivery, and effective teamwork when staffing levels and resources may be limited.
More about Weekend Rn jobs
What are the most commonly searched types of Rn jobs in Spartanburg, SC? The most popular types of Rn jobs in Spartanburg, SC are:
What are popular job titles related to Weekend Rn jobs in Spartanburg, SC? For Weekend Rn jobs in Spartanburg, SC, the most frequently searched job titles are:
What job categories do people searching Weekend Rn jobs in Spartanburg, SC look for? The top searched job categories for Weekend Rn jobs in Spartanburg, SC are:
What cities near Spartanburg, SC are hiring for Weekend Rn jobs? Cities near Spartanburg, SC with the most Weekend Rn job openings:
Weekend Rn jobs near you
Infographic showing various Weekend Rn job openings in Spartanburg, SC as of August 2026, with employment types broken down into 57% Full Time, 34% Part Time, 6% Contract, and 3% Nights. Highlights an 97% In-person, and 3% Remote job distribution, with an average salary of $84,027 per year, or $40.4 per hour.

Registered Nurse (Weekend Nurse) Pickens, SC

HEART OF A QUEEN HOMECARE SERVICES

Greenville, SC • On-site

Full-time

Re-posted 20 days ago

Job description

Benefits/Perks
  • Flexible Scheduling
  • Competitive Compensation
  • Careers Advancement 
Job Summary
We are seeking a Registered Nurse to join our team. In this role, you will primarily be creating and managing a plan of care for individual patients. You are a Registered Nurse (RN) who operates with great attention to detail and a big heart. You take pride in creating personalized care plans for patients and are able to observe and communicate effectively in your patient's best interest. To succeed, you should have demonstrated knowledge and skill in current nursing practices as well as a strong penchant for solving problems. 
Responsibilities 
  • Coordinate with other colleagues to assess, plan, implement, or evaluate patient care plans 
  • Administer medications and monitor patients for side effects or reactions  
  • Document any changes in patient conditions and report on changes 
  • Maintain accurate records of patient care and discuss observations with the supervisor  
Qualifications
  • Currently licensed Registered Nurse (RN) in state of employment 
  • Previous experience as a Registered Nurse is preferred
  • Excellent interpersonal and client care skills
  • Valid driver’s license 
  • First aid/CPR certification required