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Weekend Rn Jobs in Irvine, CA (NOW HIRING)

One Stop Hospice Inc

Hospice RN

Santa Ana, CA · On-site

$55/hr

The Hospice Registered Nurse (RN) provides compassionate, patient- and family-centered care to ... Flexibility in scheduling, including nights, weekends, holidays, and on-call duties.

One Stop Hospice Inc

Hospice RN

Santa Ana, CA · On-site

The Hospice Registered Nurse (RN) provides compassionate, patient- and family-centered care to ... Flexibility in scheduling, including nights, weekends, holidays, and on-call duties.

One Stop Hospice Inc

Hospice RN

Santa Ana, CA · On-site

$55/hr

The Hospice Registered Nurse (RN) provides compassionate, patient- and family-centered care to ... Flexibility in scheduling, including nights, weekends, holidays, and on-call duties.

One Stop Hospice Inc

Hospice RN

Santa Ana, CA · On-site

$55/hr

The Hospice Registered Nurse (RN) provides compassionate, patient- and family-centered care to ... Flexibility in scheduling, including nights, weekends, holidays, and on-call duties.

HealthSouth

Registered Nurse

Tustin, CA · On-site

$65/hr

Every other weekend work is required. Salary range is $50p/h to $65p/h DOE Registered Nurse Career Opportunity Encompass Health: Where Nursing Meets Heart, Home, and Healing Are you seeking a nursing ...

First Connect Health

RN - Medsurg

Anaheim, CA · On-site

Candidates must be flexible and available to work weekends. Preference will be given to clinicians ... Requirements * ctive RN license (license verification required) * EPIC experience required

LanceSoft

Travel Nurse RN - CVOR

Fullerton, CA · On-site

Weekend Call ONLY Certs REQ: ACLS, BCLS Is on-call REQ?: YES, Post Shift: 1700-0700, Weekend: 24HR ... LanceSoft specializes in providing Registered Nurses, Nurse Practitioners, LPNs/LVNs, Social ...

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All JobsRn JobsWeekend Rn JobsWeekend Rn Jobs in Irvine, CA

Weekend Rn information

See Irvine, CA salary details

$28

$45

$75

How much do weekend rn jobs pay per hour?

As of Aug 8, 2026, the average hourly pay for weekend rn in Irvine, CA is $45.18, according to ZipRecruiter salary data. Most workers in this role earn between $35.85 and $52.15 per hour, depending on experience, location, and employer.

What does a Weekend RN do?

As a weekend RN, you take shifts on the weekend when other nurses are unavailable, allowing hospitals and other care facilities to provide continuity of care and remain open 24/7. This is usually a part-time position, with most weekend RN's working two 8-12 hour shifts Saturday-Sunday each week. Some facilities also count Friday as a weekend day and offer a three-shift schedule instead. In this role, you may make patient visits, answer telephone calls to provide remote healthcare and address any medical emergencies that occur during your shift as a weekend nurse. As an RN, weekend work usually focuses on hospitals and hospice facilities, but you may find positions that involve traveling to visit patients outside of a clinical setting.

What are some unique challenges and rewards of working as a Weekend RN compared to a standard weekday nursing position?

Weekend RNs often face a distinct set of challenges, including managing higher patient-to-nurse ratios and handling more acute or urgent cases, as there may be fewer staff and support services available on weekends. However, this role also offers unique rewards, such as greater autonomy, opportunities to hone critical thinking and decision-making skills, and often a more flexible schedule or additional compensation. Weekend RNs typically collaborate closely with a dedicated core team, fostering strong teamwork and communication. This experience can be valuable for career advancement, as it demonstrates adaptability and strong clinical competence in a fast-paced environment.

What is the difference between Weekend Rn vs Weekend Lpn?

AspectWeekend RnWeekend Lpn
Required CredentialsRegistered Nurse license (RN)Licensed Practical Nurse license (LPN)
Work EnvironmentHospitals, clinics, long-term care facilitiesLong-term care, nursing homes, clinics
Employer & Industry UsageHospitals, healthcare agenciesLong-term care facilities, nursing homes
Common Search & Comparison IntentUnderstanding RN roles on weekendsUnderstanding LPN roles on weekends

Weekend Rn and Weekend Lpn roles differ mainly in credentials, with RNs holding a registered nurse license and LPNs holding a practical nurse license. RNs typically perform more complex medical tasks and have broader responsibilities, while LPNs focus on basic patient care. Both roles are common in healthcare settings that require weekend coverage, but RNs generally have more advanced training and scope of practice.

What is a Weekend RN?

A Weekend RN is a registered nurse who primarily works during the weekends, often covering shifts on Saturdays and Sundays. These nurses provide patient care, administer medications, monitor patient progress, and collaborate with doctors and other healthcare staff. Weekend RNs may work in hospitals, nursing homes, or other healthcare facilities, and their schedules are designed to ensure continuous high-quality care throughout the week. Weekend shifts can sometimes offer higher pay rates or shift differentials due to the non-traditional hours.

What are the key skills and qualifications needed to thrive as a Weekend RN, and why are they important?

To thrive as a Weekend RN, you need current RN licensure, strong clinical assessment skills, and experience in acute or long-term care settings. Familiarity with electronic health record (EHR) systems and up-to-date certifications such as BLS or ACLS are often required. Excellent time management, adaptability, and communication skills are essential for managing patient care during typically higher-acuity weekend shifts. These competencies ensure patient safety, efficient care delivery, and effective teamwork when staffing levels and resources may be limited.
More about Weekend Rn jobs
What are the most commonly searched types of Rn jobs in Irvine, CA? The most popular types of Rn jobs in Irvine, CA are:
What are popular job titles related to Weekend Rn jobs in Irvine, CA? For Weekend Rn jobs in Irvine, CA, the most frequently searched job titles are:
What job categories do people searching Weekend Rn jobs in Irvine, CA look for? The top searched job categories for Weekend Rn jobs in Irvine, CA are:
What cities near Irvine, CA are hiring for Weekend Rn jobs? Cities near Irvine, CA with the most Weekend Rn job openings:
Weekend Rn jobs near you
Infographic showing various Weekend Rn job openings in Irvine, CA as of August 2026, with employment types broken down into 1% As Needed, 72% Full Time, 23% Part Time, and 4% Contract. Highlights an 94% Physical, 1% Hybrid, and 5% Remote job distribution, with an average salary of $93,973 per year, or $45.2 per hour.

RN - Operating Room (Days)

St. Francis Medical Center

Norwalk, CA • On-site

Full-time

Re-posted 9 days ago

Job description

RN - Operating Room - (Days)
Position Summary
The Operating Room Registered Nurse (RN) provides direct perioperative nursing care to patients undergoing surgical procedures. The RN functions as the circulator in the operating room, ensuring patient safety, maintaining sterile technique, coordinating care among the surgical team, and delivering care throughout the perioperative experience. The RN is responsible for patient assessment, documentation, communication with physicians and surgical staff, and responding appropriately to changes in patient condition.
Key Responsibilities
  • Function as the circulating RN during surgical procedures in accordance with established perioperative standards.
  • Perform preoperative patient assessments and verify surgical consents, documentation, and procedural readiness.
  • Coordinate patient care throughout the perioperative experience and maintain patient safety.
  • Communicate effectively with surgeons, anesthesia providers, surgical technologists, and interdisciplinary team members.
  • Maintain sterile technique and ensure compliance with infection prevention and safety protocols.
  • Prepare operating rooms, equipment, and supplies for scheduled and emergent procedures.
  • Monitor patients during procedures and respond appropriately to changes in condition.
  • Complete accurate and timely documentation in the electronic medical record.
  • Participate in patient transfers, handoff communication, and postoperative care coordination.
  • Assist with equipment checks, room turnover, and supply management.
  • Participate in standby and call coverage as assigned.
  • Perform additional duties within the RN scope of practice as assigned.
Qualifications
  • Current and unencumbered California RN License.
  • Current BLS (AHA) certification.
  • Minimum 2 years of recent Operating Room experience as a Circulator RN.
  • Strong knowledge of perioperative nursing standards, sterile technique, and surgical safety practices.
Shift Details
  • Monday-Friday, 8-hour day shifts.
  • Varied start times between 0700-1530.
  • Standby/call required: approximately 2 days per week.
    • Weekday call: 16 hours.
    • Weekend call: 24 hours.
  • Two weekends of call per month.
  • Norwalk, California.

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