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Weekend Rn Jobs in Irvine, CA (NOW HIRING)

AvaMed Workforce

Registered Nurse (RN)

Chino, CA · On-site

$75/hr

Wednesday-Sunday 2pm-10:30pm or 10pm-6:30am (must be available to work on weekends) (Orientation 2 ... RN's shall provide services as permitted within the scope of practice for Registered Nurse in ...

Travel Nurses Inc

Registered Nurse (RN)

La Palma, CA · On-site

Emergency Department Registered Nurse (RN) We are looking for an Emergency Department (ED) Registered Nurse (RN) for an immediate opening in La Palma, California. You should have 1-2 years of recent ...

DaVita

Registered Nurse

Jurupa Valley, CA

$39 - $54/hr

Registered Nurse (RN) - Dialysis (ICHD) Schedule: Three days per week, 12hour shifts (Monday ... Flexible shifts including mornings, evenings, weekends, and holidays. * Training may occur at a ...

Star Nursing

RN Registered Nurse

Irvine, CA · On-site

$82/hr

Registered Nurse (RN) - Labor & Delivery (L&D) The Labor & Delivery RN provides specialized nursing care to obstetric patients throughout labor, delivery, immediate recovery, and stabilization. This ...

Star Nursing

RN Registered Nurse

Anaheim, CA · On-site

$82/hr

Registered Nurse (RN) - Labor & Delivery (L&D) The Labor & Delivery RN provides specialized nursing care to obstetric patients throughout labor, delivery, immediate recovery, and stabilization. This ...

DaVita

Registered Nurse

Riverside, CA · On-site

$39 - $54/hr

Registered Nurse (RN) - InCenter Hemodialysis (ICHD) Employment Type: Full-Time Facility: Lake ... Flexible shifts including mornings, evenings, weekends, and holidays. * Training may occur at a ...

DaVita, Inc.

Registered Nurse

Lake Elsinore, CA · On-site

$39 - $54/hr

Registered Nurse (RN) - In-Center Hemodialysis (ICHD) Employment Type: Full-Time Facility: Lake ... Flexible shifts including mornings, evenings, weekends, and holidays. * Training may occur at a ...

DaVita

Registered Nurse

Lake Elsinore, CA

$39 - $54/hr

Registered Nurse (RN) - InCenter Hemodialysis (ICHD) Employment Type: Full-Time Facility: Lake ... Flexible shifts including mornings, evenings, weekends, and holidays. * Training may occur at a ...

DaVita

Registered Nurse

Corona, CA · On-site

$39 - $54/hr

Registered Nurse (RN) - InCenter Hemodialysis (ICHD) Employment Type: Full-Time Facility: Lake ... Flexible shifts including mornings, evenings, weekends, and holidays. * Training may occur at a ...

DaVita

Registered Nurse

Corona, CA

$39 - $54/hr

Flexible shifts including mornings, evenings, weekends, and holidays. * Training may occur at a clinic other than your home location. Qualifications: * RN license in the state of practice. * ADN ...

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All JobsRn JobsWeekend Rn JobsWeekend Rn Jobs in Irvine, CA

Weekend Rn information

See Irvine, CA salary details

$28

$45

$75

How much do weekend rn jobs pay per hour?

As of Aug 8, 2026, the average hourly pay for weekend rn in Irvine, CA is $45.18, according to ZipRecruiter salary data. Most workers in this role earn between $35.85 and $52.15 per hour, depending on experience, location, and employer.

What does a Weekend RN do?

As a weekend RN, you take shifts on the weekend when other nurses are unavailable, allowing hospitals and other care facilities to provide continuity of care and remain open 24/7. This is usually a part-time position, with most weekend RN's working two 8-12 hour shifts Saturday-Sunday each week. Some facilities also count Friday as a weekend day and offer a three-shift schedule instead. In this role, you may make patient visits, answer telephone calls to provide remote healthcare and address any medical emergencies that occur during your shift as a weekend nurse. As an RN, weekend work usually focuses on hospitals and hospice facilities, but you may find positions that involve traveling to visit patients outside of a clinical setting.

What are some unique challenges and rewards of working as a Weekend RN compared to a standard weekday nursing position?

Weekend RNs often face a distinct set of challenges, including managing higher patient-to-nurse ratios and handling more acute or urgent cases, as there may be fewer staff and support services available on weekends. However, this role also offers unique rewards, such as greater autonomy, opportunities to hone critical thinking and decision-making skills, and often a more flexible schedule or additional compensation. Weekend RNs typically collaborate closely with a dedicated core team, fostering strong teamwork and communication. This experience can be valuable for career advancement, as it demonstrates adaptability and strong clinical competence in a fast-paced environment.

What is the difference between Weekend Rn vs Weekend Lpn?

AspectWeekend RnWeekend Lpn
Required CredentialsRegistered Nurse license (RN)Licensed Practical Nurse license (LPN)
Work EnvironmentHospitals, clinics, long-term care facilitiesLong-term care, nursing homes, clinics
Employer & Industry UsageHospitals, healthcare agenciesLong-term care facilities, nursing homes
Common Search & Comparison IntentUnderstanding RN roles on weekendsUnderstanding LPN roles on weekends

Weekend Rn and Weekend Lpn roles differ mainly in credentials, with RNs holding a registered nurse license and LPNs holding a practical nurse license. RNs typically perform more complex medical tasks and have broader responsibilities, while LPNs focus on basic patient care. Both roles are common in healthcare settings that require weekend coverage, but RNs generally have more advanced training and scope of practice.

What is a Weekend RN?

A Weekend RN is a registered nurse who primarily works during the weekends, often covering shifts on Saturdays and Sundays. These nurses provide patient care, administer medications, monitor patient progress, and collaborate with doctors and other healthcare staff. Weekend RNs may work in hospitals, nursing homes, or other healthcare facilities, and their schedules are designed to ensure continuous high-quality care throughout the week. Weekend shifts can sometimes offer higher pay rates or shift differentials due to the non-traditional hours.

What are the key skills and qualifications needed to thrive as a Weekend RN, and why are they important?

To thrive as a Weekend RN, you need current RN licensure, strong clinical assessment skills, and experience in acute or long-term care settings. Familiarity with electronic health record (EHR) systems and up-to-date certifications such as BLS or ACLS are often required. Excellent time management, adaptability, and communication skills are essential for managing patient care during typically higher-acuity weekend shifts. These competencies ensure patient safety, efficient care delivery, and effective teamwork when staffing levels and resources may be limited.
More about Weekend Rn jobs
What are the most commonly searched types of Rn jobs in Irvine, CA? The most popular types of Rn jobs in Irvine, CA are:
What are popular job titles related to Weekend Rn jobs in Irvine, CA? For Weekend Rn jobs in Irvine, CA, the most frequently searched job titles are:
What job categories do people searching Weekend Rn jobs in Irvine, CA look for? The top searched job categories for Weekend Rn jobs in Irvine, CA are:
What cities near Irvine, CA are hiring for Weekend Rn jobs? Cities near Irvine, CA with the most Weekend Rn job openings:
Weekend Rn jobs near you
Infographic showing various Weekend Rn job openings in Irvine, CA as of August 2026, with employment types broken down into 1% As Needed, 72% Full Time, 23% Part Time, and 4% Contract. Highlights an 94% Physical, 1% Hybrid, and 5% Remote job distribution, with an average salary of $93,973 per year, or $45.2 per hour.

Hospice Weekend RN Case Manager

Acacia Hospice of Southern California LLC

Irvine, CA • On-site

$50 - $54/hr

Part-time

Re-posted 23 days ago

Job description

We at Acacia believe in a patient first approach. You must be compassionate, caring, and work with your heart. We are more than just a team as we treat each other as family. If you are looking for a hospice agency that treats patients & team members like family, then Acacia is for you. www.acaciahealth.net

Work Location: On the road

Service Coverage Area: South Orange County

Job Description Summary:

The RN plans, organizes and directs hospice, and plans and directs services to meet the needs of patients and their families within their homes and communities.

Essential Job Functions/Responsibilities:
  • Completes an initial, comprehensive and ongoing assessment of patient and family to determine hospice needs.
  • Initiates the plan of care and makes necessary revisions as patient status and needs change.
  • Develops a care plan that establishes goals, based on nursing diagnosis and incorporates palliative nursing actions. Includes the patient and the family in the planning process.
  • Assists the patient with the activities of daily living and facilitates the patient’s efforts toward selfsufficiency and optional comfort care.
  • Acts as Case Manager and assumes responsibility to coordinate patient care for assigned caseload.
  • Completes, maintains and submits accurate and relevant clinical notes in HomecareHomebase (Pointcare).
  • Communicates with the physician regarding the patient’s needs and reports changes in the patient’s condition; obtains/receives physicians’ orders as required.
  • Teaches the patient and family/caregiver selfcare techniques as appropriate.
  • Attends interdisciplinary group meetings.
  • Fulfills the obligation of requested and/or accepted case assignments.
    • Position Qualifications:
  • CA RN License
  • Compassionate & Caring
  • HomecareHomebase (Pointcare) Experience
  • CPR certification
  • CA Driver License

    • Location: All of OC up to Torrance

    Job Type: Part-time

    Schedule:
  • 8 hour shift
  • Weekend RN
    • Experience:
  • Hospice: 1 year (Required)
    • License/Certification:
  • California RN license (Required)

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