Registered Nurse (RN) - Local, and PRN Opportunities Various Schedules : AM & PM Shifts What You'll Do: The Registered Nurse (RN) is responsible for delivering patient-centered care by assessing ...
Quick apply
Registered Nurse (RN) - Local, and PRN Opportunities Various Schedules : AM & PM Shifts What You'll Do: The Registered Nurse (RN) is responsible for delivering patient-centered care by assessing ...
Quick apply
Registered Nurse (RN) - Local, and PRN Opportunities Various Schedules : AM & PM Shifts What You'll Do: The Registered Nurse (RN) is responsible for delivering patient-centered care by assessing ...
Columbia, SC · On-site
PRN Registered Nurses (RN) Wanted! White Oak Manor of Columbia | Compassion. Dedication. Excellence. Are you a compassionate and skilled Registered Nurse looking to make a real impact in the lives of ...
Columbia, SC · On-site
PRN Registered Nurses (RN) Wanted! White Oak Manor of Columbia | Compassion. Dedication. Excellence. Are you a compassionate and skilled Registered Nurse looking to make a real impact in the lives of ...
Now Hiring Full Time, Part Time and PRN RNs for Day Shift and Night Shift * CRRN Position Available Encompass Health: Where Nursing Meets Heart, Home, and Healing Are you seeking a nursing career ...
Now Hiring Full Time, Part Time and PRN RNs for Day Shift and Night Shift * CRRN Position Available Encompass Health: Where Nursing Meets Heart, Home, and Healing Are you seeking a nursing career ...
Registered Nurse Career Opportunity * $10,000 Sign on Bonus for Full Time RNs! * Now Hiring Full Time, Part Time and PRN RNs for Day Shift and Night Shift Encompass Health: Where Nursing Meets Heart ...
Registered Nurse Career Opportunity * $10,000 Sign on Bonus for Full Time RNs! * Now Hiring Full Time, Part Time and PRN RNs for Day Shift and Night Shift Encompass Health: Where Nursing Meets Heart ...
PRN Healthcare is seeking a travel nurse RN Endoscopy for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: Endoscopy * Discipline: RN * Start Date: 07/06/2026 * Duration ...
PRN Healthcare is seeking a travel nurse RN Endoscopy for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: Endoscopy * Discipline: RN * Start Date: 07/06/2026 * Duration ...
PRN Healthcare is seeking a travel nurse RN CVICU for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: CVICU * Discipline: RN * Start Date: 06/29/2026 * Duration: 13 ...
PRN Healthcare is seeking a travel nurse RN CVICU for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: CVICU * Discipline: RN * Start Date: 06/29/2026 * Duration: 13 ...
PRN Healthcare is seeking a travel nurse RN CCU - Coronary Care for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: CCU - Coronary Care * Discipline: RN * Start Date: 06 ...
PRN Healthcare is seeking a travel nurse RN CCU - Coronary Care for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: CCU - Coronary Care * Discipline: RN * Start Date: 06 ...
Columbia, SC · On-site
$1K/wk
PRN Healthcare is seeking a travel nurse RN Endoscopy for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: Endoscopy * Discipline: RN * Start Date: 07/06/2026 * Duration ...
New
Columbia, SC · On-site
$1K/wk
PRN Healthcare is seeking a travel nurse RN Endoscopy for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: Endoscopy * Discipline: RN * Start Date: 07/06/2026 * Duration ...
New
Columbia, SC · On-site
$30 - $45/hr
Registered Nurse, RN PRN Aiken County Position: Registered Nurse, RN PRN Pay: $30.00 - $45.00 / hourly Depending on Experience and Responsibilities Caris Healthcare RN provides nursing care to ...
Columbia, SC · On-site
$30 - $45/hr
Registered Nurse, RN PRN Aiken County Position: Registered Nurse, RN PRN Pay: $30.00 - $45.00 / hourly Depending on Experience and Responsibilities Caris Healthcare RN provides nursing care to ...
PRN Healthcare is seeking a travel nurse RN Labor and Delivery for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: Labor and Delivery * Discipline: RN * Start Date: 06 ...
PRN Healthcare is seeking a travel nurse RN Labor and Delivery for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: Labor and Delivery * Discipline: RN * Start Date: 06 ...
PRN Healthcare is seeking a travel nurse RN Labor and Delivery for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: Labor and Delivery * Discipline: RN * Start Date: 07 ...
PRN Healthcare is seeking a travel nurse RN Labor and Delivery for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: Labor and Delivery * Discipline: RN * Start Date: 07 ...
Columbia, SC · On-site
$1K - $2K/wk
PRN Healthcare is seeking a travel nurse RN PCU - Progressive Care Unit for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: PCU - Progressive Care Unit * Discipline: RN ...
Columbia, SC · On-site
$1K - $2K/wk
PRN Healthcare is seeking a travel nurse RN PCU - Progressive Care Unit for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: PCU - Progressive Care Unit * Discipline: RN ...
Columbia, SC · On-site
$1K/wk
PRN Healthcare is seeking a travel nurse RN CCU - Coronary Care for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: CCU - Coronary Care * Discipline: RN * Start Date: 06 ...
New
Columbia, SC · On-site
$1K/wk
PRN Healthcare is seeking a travel nurse RN CCU - Coronary Care for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: CCU - Coronary Care * Discipline: RN * Start Date: 06 ...
New
Columbia, SC · On-site
$1K/wk
PRN Healthcare is seeking a travel nurse RN CVICU for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: CVICU * Discipline: RN * Start Date: 06/29/2026 * Duration: 13 ...
New
Columbia, SC · On-site
$1K/wk
PRN Healthcare is seeking a travel nurse RN CVICU for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: CVICU * Discipline: RN * Start Date: 06/29/2026 * Duration: 13 ...
New
PRN Healthcare is seeking a travel nurse RN Labor and Delivery for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: Labor and Delivery * Discipline: RN * Start Date: 07 ...
New
PRN Healthcare is seeking a travel nurse RN Labor and Delivery for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: Labor and Delivery * Discipline: RN * Start Date: 07 ...
New
Columbia, SC · On-site
$1K/wk
PRN Healthcare is seeking a travel nurse RN Labor and Delivery for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: Labor and Delivery * Discipline: RN * Start Date: 06 ...
New
Columbia, SC · On-site
$1K/wk
PRN Healthcare is seeking a travel nurse RN Labor and Delivery for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: Labor and Delivery * Discipline: RN * Start Date: 06 ...
New
Columbia, SC · On-site
$1K/wk
PRN Healthcare is seeking a travel nurse RN PCU - Progressive Care Unit for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: PCU - Progressive Care Unit * Discipline: RN ...
New
Columbia, SC · On-site
$1K/wk
PRN Healthcare is seeking a travel nurse RN PCU - Progressive Care Unit for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: PCU - Progressive Care Unit * Discipline: RN ...
New
PRN Healthcare is seeking a travel nurse RN Endoscopy for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: Endoscopy * Discipline: RN * Start Date: 07/06/2026 * Duration ...
New
PRN Healthcare is seeking a travel nurse RN Endoscopy for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: Endoscopy * Discipline: RN * Start Date: 07/06/2026 * Duration ...
New
Columbia, SC · On-site
$30 - $45/hr
Registered Nurse, RN PRN Pay: $30.00 - $45.00 / hourly Depending on Experience and Responsibilities Caris Healthcare RN provides nursing care to patients per the physician's orders. The hallmarks of ...
Columbia, SC · On-site
$30 - $45/hr
Registered Nurse, RN PRN Pay: $30.00 - $45.00 / hourly Depending on Experience and Responsibilities Caris Healthcare RN provides nursing care to patients per the physician's orders. The hallmarks of ...
Columbia, SC · On-site
Certification and recertification expenses can be reimbursed for eligible RNs such as Immune Globulin Certified Nurse (IgCN)! In this PRN role, you will visit patients in greater Columbia and ...
Columbia, SC · On-site
Certification and recertification expenses can be reimbursed for eligible RNs such as Immune Globulin Certified Nurse (IgCN)! In this PRN role, you will visit patients in greater Columbia and ...
$17.34 - $20.12
2% of jobs
$20.12 - $22.91
5% of jobs
$22.91 - $25.69
14% of jobs
$26.13 is the 25th percentile. Wages below this are outliers.
$25.69 - $28.47
23% of jobs
The median wage is $30.46 / hr.
$28.47 - $31.26
7% of jobs
$31.26 - $34.04
14% of jobs
$36.01 is the 75th percentile. Wages above this are outliers.
$34.04 - $36.82
13% of jobs
$36.82 - $39.60
4% of jobs
$39.60 - $42.39
4% of jobs
$42.39 - $45.17
7% of jobs
$45.17 - $47.95
5% of jobs
$17
$32
$47
Weekend PRN RN positions usually require nurses to work flexible hours on Saturdays and Sundays, with potential opportunities for additional shifts based on staffing needs. The workload can vary each weekend, depending on patient census and acuity, so adaptability is important. These roles often involve collaborating with a leaner weekend team, requiring strong teamwork and autonomy. While you may not have a set schedule every week, PRN positions can offer valuable hands-on experience and are ideal for nurses seeking flexibility or supplemental income.
To thrive as a Weekend PRN RN, you need a current RN license, strong clinical assessment abilities, and experience in acute or long-term care settings. Familiarity with electronic health record (EHR) systems, medication administration protocols, and facility-specific safety procedures is important. Flexibility, excellent communication, and the ability to work independently are valuable soft skills for managing varied shifts and patient needs. These competencies ensure that you can provide high-quality care and respond effectively to weekend staffing and patient demands.
A Weekend PRN RN (As Needed Registered Nurse) is a nursing position where the nurse works primarily on weekends and on an as-needed basis. These roles are typically found in hospitals, nursing homes, and healthcare facilities that require additional weekend staffing. PRN nurses do not usually have a set schedule and may be called to fill in for staff shortages. This role offers flexibility but may not guarantee a certain number of hours. Weekend PRN RNs must still meet licensing and certification requirements like full-time nurses.

Contractor
Posted 5 days ago
Patient Care:
Perform comprehensive assessments of patient conditions.
Develop and implement individualized care plans.
Administer medications, treatments, and therapies as prescribed.
Monitor and record vital signs, progress, and responses to treatment.
Provide patient education and emotional support to patients and their families.
Collaboration:
Work closely with physicians, healthcare teams, and support staff to ensure coordinated and effective care.
Communicate patient status and any changes to the healthcare team promptly.
Participate in interdisciplinary team meetings and contribute to care planning.
Adaptability:
Quickly familiarize yourself with new healthcare settings, protocols, and equipment.
Adjust to different work environments, including hospitals, clinics, or long-term care facilities.
Provide nursing care in diverse patient populations and healthcare units (ICU, ER, Med-Surg, etc.).
Documentation and Compliance:
Maintain accurate and up-to-date patient records in compliance with facility policies and regulatory standards.
Ensure adherence to all safety protocols, infection control measures, and state/national nursing standards.
Participate in continuing education and training as required to maintain nursing license and certifications.
Travel/PRN Specific Duties (if applicable):
Travel RNs: Commit to assignments at various locations, potentially nationwide, and adapt to each facility's needs and patient care protocols.
PRN RNs: Be available to work on an on-call, as-needed basis, covering shifts during peak demand periods, staff shortages, or emergencies.
Local RNs: Provide nursing care in a consistent, local facility with flexible or per diem scheduling options.