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Weekend Prn Rn Jobs in Lexington, SC (NOW HIRING)

TNAA TotalMed RN

Travel MS/Tele RN

Columbia, SC · On-site

$1.6K - $2.2K/wk

TNAA TotalMed RN is seeking a travel nurse RN Med Surg / Telemetry for a travel nursing job in ... TotalMed specializes in recruiting and placing healthcare professionals in travel, PRN, and ...

TNAA TotalMed RN

Travel ER RN

Columbia, SC · On-site

TNAA TotalMed RN is seeking a travel nurse RN ED - Emergency Department for a travel nursing job in ... TotalMed specializes in recruiting and placing healthcare professionals in travel, PRN, and ...

PRN Healthcare

Travel Cath Lab RN

Columbia, SC · On-site

PRN Healthcare is seeking a travel nurse RN Cardiac Cath Lab for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: Cardiac Cath Lab * Discipline: RN * Start Date: ASAP

PRN Healthcare

Travel Med Surg Telemetry RN

Columbia, SC · On-site

$1.6K - $2.2K/wk

PRN Healthcare is seeking a travel nurse RN Med Surg / Telemetry for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: Med Surg / Telemetry * Discipline: RN * Start Date ...

TNAA TotalMed RN

Travel Med Surg Telemetry RN

Columbia, SC · On-site

$1.6K - $2.2K/wk

TNAA TotalMed RN is seeking a travel nurse RN Med Surg / Telemetry for a travel nursing job in ... TotalMed specializes in recruiting and placing healthcare professionals in travel, PRN, and ...

TNAA TotalMed RN

Travel IMC RN

Columbia, SC · On-site

TNAA TotalMed RN is seeking a travel nurse RN Intermediate Care for a travel nursing job in ... TotalMed specializes in recruiting and placing healthcare professionals in travel, PRN, and ...

TNAA TotalMed RN

Travel Cath Lab RN

Columbia, SC · On-site

TNAA TotalMed RN is seeking a travel nurse RN Cardiac Cath Lab for a travel nursing job in Columbia ... TotalMed specializes in recruiting and placing healthcare professionals in travel, PRN, and ...

PRN Healthcare

Travel Cardiac ICU RN

Columbia, SC · On-site

PRN Healthcare is seeking a travel nurse RN CCU - Coronary Care for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: CCU - Coronary Care * Discipline: RN * Start Date: 09 ...

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All JobsPrn Rn JobsWeekend Prn Rn JobsWeekend Prn Rn Jobs in Lexington, SC

Weekend Prn Rn information

See Lexington, SC salary details

$16

$31

$46

How much do weekend prn rn jobs pay per hour?

As of Sep 2, 2026, the average hourly pay for weekend prn rn in Lexington, SC is $31.22, according to ZipRecruiter salary data. Most workers in this role earn between $24.90 and $36.01 per hour, depending on experience, location, and employer.

What is a Weekend PRN RN?

A Weekend PRN RN (As Needed Registered Nurse) is a nursing position where the nurse works primarily on weekends and on an as-needed basis. These roles are typically found in hospitals, nursing homes, and healthcare facilities that require additional weekend staffing. PRN nurses do not usually have a set schedule and may be called to fill in for staff shortages. This role offers flexibility but may not guarantee a certain number of hours. Weekend PRN RNs must still meet licensing and certification requirements like full-time nurses.

What are the typical shift expectations and workload for a Weekend PRN RN?

Weekend PRN RN positions usually require nurses to work flexible hours on Saturdays and Sundays, with potential opportunities for additional shifts based on staffing needs. The workload can vary each weekend, depending on patient census and acuity, so adaptability is important. These roles often involve collaborating with a leaner weekend team, requiring strong teamwork and autonomy. While you may not have a set schedule every week, PRN positions can offer valuable hands-on experience and are ideal for nurses seeking flexibility or supplemental income.

What are the key skills and qualifications needed to thrive in the Weekend PRN RN position, and why are they important?

To thrive as a Weekend PRN RN, you need a current RN license, strong clinical assessment abilities, and experience in acute or long-term care settings. Familiarity with electronic health record (EHR) systems, medication administration protocols, and facility-specific safety procedures is important. Flexibility, excellent communication, and the ability to work independently are valuable soft skills for managing varied shifts and patient needs. These competencies ensure that you can provide high-quality care and respond effectively to weekend staffing and patient demands.

Do PRN registered nurses have to work weekends?

PRN registered nurses are scheduled on an as-needed basis and are not typically required to work weekends unless assigned to weekend shifts. Their work schedule depends on the facility's staffing needs and the nurse's availability, often offering flexibility. However, some PRN positions may include weekend shifts if the facility requires coverage during those times.

What are the most commonly searched types of Prn Rn jobs in Lexington, SC?

The most popular types of Prn Rn jobs in Lexington, SC are:

What are popular job titles related to Weekend Prn Rn jobs in Lexington, SC?

For Weekend Prn Rn jobs in Lexington, SC, the most frequently searched job titles are:

What job categories do people searching Weekend Prn Rn jobs in Lexington, SC look for?

The top searched job categories for Weekend Prn Rn jobs in Lexington, SC are:

What cities near Lexington, SC are hiring for Weekend Prn Rn jobs?

Cities near Lexington, SC with the most Weekend Prn Rn job openings:

Weekend Prn Rn jobs near you
Infographic showing various Weekend Prn Rn job openings in Lexington, SC as of August 2026, with employment types broken down into 13% As Needed, 32% Full Time, 23% Part Time, and 32% Contract. Highlights an 100% In-person job distribution, with an average salary of $64,937 per year, or $31.2 per hour.

PRN Nurse RNHome Care

GRACEFUL TOUCH HOME CARE LLC

Columbia, SC • On-site

Other

This job post has expired 1 day ago. Applications are no longer accepted.

Job description

enefits/Perks

Flexible Scheduling

Competitive Compensation

Careers Advancement

Position Summary:

Seeking a compassionate and professional PRN Nurse RN to conduct home visits and provide high-quality, individualized care to clients in their residences. This is an excellent opportunity for a nurse looking to supplement their schedule with flexible hours, minimal documentation, and meaningful patient interactions.

Key Responsibilities:

Conduct in-home patient assessments, including health history, physical exams, and evaluations of the home environment

Monitor patient conditions, vital signs, and report changes to the supervising nurse or agency

Assess health status and develop individualized, comprehensive care plans tailored to client needs

Document care provided and health status updates with accuracy and efficiency

Educate patients and families on disease prevention, medication management, and overall health maintenance

Collaborate with the care team to ensure coordinated and effective service

Provide care with empathy, respect, and strong communication skills

Requirements:

Current and valid RN or LPN license in the state of South Carolina

Minimum of 1 year of clinical nursing experience (home care preferred)

CPR certification (BLS)

Reliable transportation and valid driver’s license

Strong time management and independent decision-making skills

Ability to travel within the designated service area

Work Details:

PRN (as-needed) availability required

Home visits required; each visit lasts approximately 30 minutes

Minimal documentation required following each visit

Must be able to travel independently to client homes within the service area

Join our team and help make a difference—one home at a time.

Apply