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Weekend Prn Rn Jobs in Lexington, SC (NOW HIRING)

UHS

Registered Nurse RN PRN

West Columbia, SC · On-site

One of the most rewarding aspects of working as a Registered Nurse (RN) is providing excellent care, comfort, and security to the patients and families you treat, at their most vulnerable times. You ...

PRN Healthcare Services

SDU - RN

Columbia, SC · On-site

SDU RN Columbia, SC South Carolina is the perfect place for traveling medical professionals to live ... Your adventure starts here with PRN Healthcare! Take control of your career with a travel contract ...

UHS

Registered Nurse RN PRN

West Columbia, SC · On-site

One of the most rewarding aspects of working as a Registered Nurse (RN) is providing excellent care, comfort, and security to the patients and families you treat, at their most vulnerable times. You ...

Amedisys, Inc.

RN Hospice Nurse PRN

West Columbia, SC · On-site

$38 - $40.50/hr

Overview PRN Hospice Registered Nurse (Home Visits) Are you looking for a rewarding career in hospice? If so, we invite you to join our team at Amedisys, one of the largest and most trusted home ...

Amedisys, Inc.

RN Hospice Nurse PRN

West Columbia, SC

$38 - $40.50/hr

Overview PRN Hospice Registered Nurse (Home Visits) Are you looking for a rewarding career in hospice? If so, we invite you to join our team at Amedisys, one of the largest and most trusted home ...

Amedisys, Inc.

RN Hospice Nurse PRN

West Columbia, SC · On-site

$38 - $40.50/hr

Overview PRN Hospice Registered Nurse (Home Visits) Are you looking for a rewarding career in hospice? If so, we invite you to join our team at Amedisys, one of the largest and most trusted home ...

Amedisys, Inc.

RN Hospice Nurse PRN

West Columbia, SC · On-site

$38 - $40.50/hr

Overview PRN Hospice Registered Nurse (Home Visits) Are you looking for a rewarding career in hospice? If so, we invite you to join our team at Amedisys, one of the largest and most trusted home ...

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All JobsWeekend Prn Rn JobsWeekend Prn Rn Jobs in Lexington, SC

Weekend Prn Rn information

See Lexington, SC salary details

$16

$31

$46

How much do weekend prn rn jobs pay per hour?

As of Jul 3, 2026, the average hourly pay for weekend prn rn in Lexington, SC is $31.22, according to ZipRecruiter salary data. Most workers in this role earn between $24.90 and $36.01 per hour, depending on experience, location, and employer.

How to make $300,000 as a nurse?

To earn $300,000 as a Weekend PRN RN, nurses can increase their income by working multiple shifts, obtaining specialized certifications, and gaining experience in high-demand areas like critical care or anesthesia. Some may also supplement income through travel nursing or per diem assignments that pay higher rates for weekend shifts.

What are the typical shift expectations and workload for a Weekend PRN RN position?

Weekend PRN RN positions usually require nurses to work flexible hours on Saturdays and Sundays, with potential opportunities for additional shifts based on staffing needs. The workload can vary each weekend, depending on patient census and acuity, so adaptability is important. These roles often involve collaborating with a leaner weekend team, requiring strong teamwork and autonomy. While you may not have a set schedule every week, PRN positions can offer valuable hands-on experience and are ideal for nurses seeking flexibility or supplemental income.

What are the key skills and qualifications needed to thrive in the Weekend Prn Rn position, and why are they important?

To thrive as a Weekend PRN RN, you need a current RN license, strong clinical assessment abilities, and experience in acute or long-term care settings. Familiarity with electronic health record (EHR) systems, medication administration protocols, and facility-specific safety procedures is important. Flexibility, excellent communication, and the ability to work independently are valuable soft skills for managing varied shifts and patient needs. These competencies ensure that you can provide high-quality care and respond effectively to weekend staffing and patient demands.

Do PRN nurses have to work weekends?

PRN (as-needed) RNs working weekends depends on the facility's staffing needs and scheduling policies. Some PRN nurses choose to work weekends, while others may have the option to decline, as PRN positions typically offer flexible hours. It is important to clarify scheduling expectations with the employer before accepting the role.

How to make 150,000 as a nurse?

To earn $150,000 as a Weekend PRN RN, nurses can increase their hourly rate through specialized skills, certifications, or working in high-demand areas such as intensive care or emergency rooms. Working additional shifts, overtime, or in multiple facilities can also boost income, especially when scheduling is flexible on weekends. Building experience and negotiating pay rates are key factors in reaching higher salary goals.

What is a Weekend PRN RN job?

A Weekend PRN RN (As Needed Registered Nurse) is a nursing position where the nurse works primarily on weekends and on an as-needed basis. These roles are typically found in hospitals, nursing homes, and healthcare facilities that require additional weekend staffing. PRN nurses do not usually have a set schedule and may be called to fill in for staff shortages. This role offers flexibility but may not guarantee a certain number of hours. Weekend PRN RNs must still meet licensing and certification requirements like full-time nurses.

How to make an extra $2000 a month as a nurse?

A Weekend PRN RN can increase income by taking on additional shifts, working overtime, or picking up per diem assignments during busy periods. Gaining specialized certifications or skills, such as in critical care or anesthesia, can also command higher pay rates. Scheduling flexibility and experience can help maximize earning potential to reach an extra $2000 monthly.
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Weekend Prn Rn jobs near you
Infographic showing various Weekend Prn Rn job openings in Lexington, SC as of June 2026, with employment types broken down into 3% As Needed, 54% Full Time, 10% Part Time, and 33% Contract. Highlights an 99% Physical, and 1% Remote job distribution, with an average salary of $64,937 per year, or $31.2 per hour.
Licensed Practical Nurse (LPN) / Registered Nurse (RN) - Private Duty Pediatric Nurse

Licensed Practical Nurse (LPN) / Registered Nurse (RN) - Private Duty Pediatric Nurse

Angels of Care Pediatric Home Health

Columbia, SC • On-site

$29/hr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 4 days ago

Angels Of Care rating

6.7

Company rating: 6.7 out of 10

Based on 38 frontline employees who took The Breakroom Quiz

55th of 232 rated social care providers

Job description

Description
Licensed Practical Nurse (LPN) / Registered Nurse (RN) - Private Duty Pediatric Nurse
Columbia, SC Surrounding Areas
Pay Range: $29+/hour
Make a Difference One Patient at a Time
Angels of Care Pediatric Home Health is hiring Registered Nurses (RNs) and Licensed Practical Nurses (LPNs) to provide one-on-one, in-home care for medically fragile children and young adults.
This role is ideal for nurses who are passionate about building meaningful relationships with patients and families while delivering high-quality, individualized care in the home setting.
Angels of Care is a nurse-founded, clinically led organization that has proudly served the medically fragile community since 2000. We are driven by our core values: Heart, Advocacy, Love, Outreach, and Speed (#HALOS).
Why Join Angels of Care?
  • One-on-one, patient-centered pediatric care
  • Flexible scheduling (full-time, part-time, PRN)
  • Days, nights, and weekend shifts available
  • 24/7 clinical and operational support
  • Paid training, simulation lab experiences, and continuing education
  • Weekly pay and reliable scheduling
  • Supportive, mission-driven team culture
  • Opportunities for career growth and advancement

What You'll Do
  • Provide skilled nursing care in a home health setting
  • Perform ongoing patient assessments and clinical evaluations
  • Administer prescribed medications, treatments, and therapies
  • Deliver care in accordance with physician orders and plan of care
  • Coordinate care with families, providers, and care teams
  • Educate patients and family members to support improved outcomes
  • Implement preventive measures to ensure patient safety and quality care
  • Respond appropriately to changes in patient condition

Qualifications
Required:
  • Active, unrestricted Registered Nurse (RN) or Licensed Practical Nurse (LPN) license (South Carolina)
  • License acquired 1 year prior to application
  • Ability to provide care in a home setting
  • Strong communication and clinical decision-making skills

Preferred:
  • Pediatric or home health experience
  • Experience with high-acuity skills (trach, vent, G-tube)

Schedule & Flexibility
  • Full-time, part-time, and PRN opportunities
  • Flexible scheduling based on your availability
  • 8, 10, 12, or 16-hour shifts available

Why Angels of Care:
We have a full benefits package, bulleted out below. Among these great benefits, we have fun! We attend and invite our employees to community events and volunteer opportunities, keep you informed on ways you can help advocate for our medically fragile kids, cook-out on Employee Appreciation Day, and so much more!
  • Major medical, dental, & vision plans with a generous portion of medical covered by AOC
  • Group & voluntary life insurance
  • 401K
  • Paid time off
  • Employee Assistance Program
  • Supplemental Insurance Policies
  • Patient Care Coordination Services
  • Prescription Concierge Service
  • Anytime Fitness gym discount
  • Voluntary long-term & short-term disability
  • Free life insurance
  • Cellular discounts
  • Health savings account
  • Dependent care flexible spending account
  • Wellness program & incentives
  • Legal Shield & Identity Shield
  • Flexible Spending Accounts (FSA)
  • Annual car giveaway
  • and many more!

Our Mission
We provide children and young adults in need with high-quality home health care in a loving, caring, and professional manner.
Our Vision
To be recognized as the very best pediatric home health agency.
Our Values (#HALOS)
  • Heart - Patients come first in everything we do
  • Advocacy - We champion our clients, clinicians, and industry
  • Love - We care deeply about our employees and families
  • Outreach - We engage and give back to our communities
  • Speed - We act quickly to meet the needs of our patients

U.S. Equal Employment Opportunity/Affirmative Action Information
Individuals seeking employment at Angels of Care Pediatric Home Health are considered without regards to race, color, religion, sex, sexual orientation, gender identification, national origin, age, marital status, ancestry, physical or mental disability, or veteran status.
Must submit a resume to be considered for this position

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