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Weekend Prn Rn Jobs in Lexington, SC (NOW HIRING)

TNAA TotalMed RN

Travel OR RN

Columbia, SC · On-site

  • Medical

  • Dental

  • Vision

  • Retirement

TNAA TotalMed RN is seeking a travel nurse RN OR - Operating Room for a travel nursing job in ... TotalMed specializes in recruiting and placing healthcare professionals in travel, PRN, and ...

New

PRN Healthcare

Travel Labor and Delivery RN

Columbia, SC · On-site

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

PRN Healthcare is seeking a travel nurse RN Labor and Delivery for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: Labor and Delivery * Discipline: RN * Start Date: 08 ...

New

PRN Healthcare

Travel Labor and Delivery RN

Columbia, SC · On-site

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

PRN Healthcare is seeking a travel nurse RN Labor and Delivery for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: Labor and Delivery * Discipline: RN * Start Date: 08 ...

New

PRN Healthcare

Travel ECMO Specialist RN

Columbia, SC · On-site

$1.8K - $2.4K/wk

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

PRN Healthcare is seeking a travel nurse RN CVICU for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: CVICU * Discipline: RN * Start Date: 08/31/2026 * Duration: 13 ...

TNAA TotalMed RN

Travel ECMO Specialist RN

Columbia, SC · On-site

  • Medical

  • Dental

  • Vision

  • Retirement

TNAA TotalMed RN is seeking a travel nurse RN CVICU for a travel nursing job in Columbia, South ... TotalMed specializes in recruiting and placing healthcare professionals in travel, PRN, and ...

TNAA TotalMed RN

Travel LTAC ICU RN

Columbia, SC · On-site

$1.5K - $2.0K/wk

  • Medical

  • Dental

  • Vision

  • Retirement

TNAA TotalMed RN is seeking a travel nurse RN Long Term Acute Care for a travel nursing job in ... TotalMed specializes in recruiting and placing healthcare professionals in travel, PRN, and ...

New

TNAA TotalMed RN

Travel LTAC ICU RN

Columbia, SC · On-site

$1.5K - $2.0K/wk

  • Medical

  • Dental

  • Vision

  • Retirement

TNAA TotalMed RN is seeking a travel nurse RN Long Term Acute Care ICU - Intensive Care Unit for a ... TotalMed specializes in recruiting and placing healthcare professionals in travel, PRN, and ...

New

Summit BHC

RN- PRN

Peak, SC · On-site

RN- PRN | Peak Behavioral Health | Santa Teresa, New Mexico About the Job: PURPOSE STATEMENT: The Registered Nurse is responsible for providing nursing care to patients. Supervising care treatment ...

Summit BHC

RN (PRN)

Peak, SC · On-site

RN (PRN) | Peak Behavioral Health | Santa Teresa, New Mexico About the Job: PURPOSE STATEMENT: The Registered Nurse is responsible for providing nursing care to patients. Supervising care treatment ...

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Showing results 21-40

All JobsPrn Rn JobsWeekend Prn Rn JobsWeekend Prn Rn Jobs in Lexington, SC

Weekend Prn Rn information

See Lexington, SC salary details

$16

$31

$46

How much do weekend prn rn jobs pay per hour?

As of Aug 13, 2026, the average hourly pay for weekend prn rn in Lexington, SC is $31.22, according to ZipRecruiter salary data. Most workers in this role earn between $24.90 and $36.01 per hour, depending on experience, location, and employer.

What are the typical shift expectations and workload for a Weekend PRN RN?

Weekend PRN RN positions usually require nurses to work flexible hours on Saturdays and Sundays, with potential opportunities for additional shifts based on staffing needs. The workload can vary each weekend, depending on patient census and acuity, so adaptability is important. These roles often involve collaborating with a leaner weekend team, requiring strong teamwork and autonomy. While you may not have a set schedule every week, PRN positions can offer valuable hands-on experience and are ideal for nurses seeking flexibility or supplemental income.

What are the key skills and qualifications needed to thrive in the Weekend PRN RN position, and why are they important?

To thrive as a Weekend PRN RN, you need a current RN license, strong clinical assessment abilities, and experience in acute or long-term care settings. Familiarity with electronic health record (EHR) systems, medication administration protocols, and facility-specific safety procedures is important. Flexibility, excellent communication, and the ability to work independently are valuable soft skills for managing varied shifts and patient needs. These competencies ensure that you can provide high-quality care and respond effectively to weekend staffing and patient demands.

What is a Weekend PRN RN?

A Weekend PRN RN (As Needed Registered Nurse) is a nursing position where the nurse works primarily on weekends and on an as-needed basis. These roles are typically found in hospitals, nursing homes, and healthcare facilities that require additional weekend staffing. PRN nurses do not usually have a set schedule and may be called to fill in for staff shortages. This role offers flexibility but may not guarantee a certain number of hours. Weekend PRN RNs must still meet licensing and certification requirements like full-time nurses.

What are the most commonly searched types of Prn Rn jobs in Lexington, SC? The most popular types of Prn Rn jobs in Lexington, SC are:
What are popular job titles related to Weekend Prn Rn jobs in Lexington, SC? For Weekend Prn Rn jobs in Lexington, SC, the most frequently searched job titles are:
What job categories do people searching Weekend Prn Rn jobs in Lexington, SC look for? The top searched job categories for Weekend Prn Rn jobs in Lexington, SC are:
What cities near Lexington, SC are hiring for Weekend Prn Rn jobs? Cities near Lexington, SC with the most Weekend Prn Rn job openings:
Weekend Prn Rn jobs near you
Infographic showing various Weekend Prn Rn job openings in Lexington, SC as of August 2026, with employment types broken down into 13% As Needed, 34% Full Time, 20% Part Time, 31% Contract, and 2% Nights. Highlights an 96% In-person, and 4% Remote job distribution, with an average salary of $64,937 per year, or $31.2 per hour.

Hospice Registered Nurse (RN) - PRN

Interim HealthCare of the Midlands

Cayce, SC • On-site

$38 - $41.30/hr

Full-time

Retirement

Posted 8 days ago

Job description

It’s been said that people will forget what you say and what you do, but never how you make them feel. Hospice nurses are special in that they bring not only strong clinical skills but also a heartfelt commitment to ensuring that patients and their families receive comfort, understanding, and unwavering support during one of life's most meaningful transitions. We are seeking a compassionate and experienced Hospice Registered Nurse (RN) who is dedicated to leading with empathy, clinical excellence, and a deep respect for patient dignity. In this vital role, you will deliver exceptional, patient-centered end-of-life care that honors everyone's journey.

Guided by our mission to honor God through the enrichment of human life, Interim HealthCare has been a trusted leader in home health and hospice services across South Carolina since 1979 and is proud to be recognized as a 9x Top Workplace. We believe exceptional care begins with supported nurses, and we foster an environment where clinicians are respected, empowered, and equipped to do meaningful work—if you’re ready to make a lasting difference in patients’ lives, we invite you to join our team.

Why You’ll Love Working with Interim 

As a PRN Hospice Registered Nurse (RN) with Interim, you’ll enjoy:

  • Competitive compensation ranging from $38.00 - $41.30/ hour DOE, plus mileage reimbursement
  • Flexible scheduling that supports true work-life balance and autonomy
  • Dedicated 1:1 patient care, allowing you to focus on quality care, not volume
  • 401(k) with employer match to help you plan confidently for the future
  • Support for your growth and well-being, including free CEUs, tuition assistance, and fitness reimbursement

What You’ll Do 

As a PRN Hospice Registered Nurse (RN), you will:

  • Completes an initial/comprehensive assessment of the patient/family to determine hospice needs.
  • Completes ongoing assessments of the patient’s physical status and the psycho-social status of the patient/family.
  • Initiates and develops a plan of care in collaboration with the IDG, the patient/family, and the physician.
  • Makes necessary revisions to the IDG plan of care as the patient’s/family’s status and needs change.
  • Primarily responsible for the coordination of care among IDG members and other providers external to the IDG to ensure the continuous assessment of the patient/family needs, as well as the implementation of the IDG plan of care to guide the delivery of services and achieve the goals of hospice care.
  • Evaluates and coordinates the need for services provided to the patient/family in accordance with the IDG plan of care.
  • Administers medications and treatments as prescribed by the physician in accordance with nursing standards of practice.
  • Provides education and interventions to support the effective management of the patient’s pain and other physical symptoms as well as assesses the patient/family’s response to intervention and treatment

What You’ll Need 

  • Graduate of an accredited Registered Nurse (RN) program 
  • Active South Carolina RN license or Compact License 
  • Minimum one year of nursing experience 
  • Hospice experience preferred 

Apply Today 

If you are a Hospice Registered Nurse (RN) looking for a rewarding Hospice opportunity in Columbia, SC, we encourage you to apply and join a compassionate, patient focused team.  

Interim HealthCare is an equal opportunity employer that is committed to diversity and inclusion in the workplace. We prohibit discrimination and harassment of any kind based on race, color, sex, religion, sexual orientation, national origin, disability, genetic information, pregnancy, or any other protected characteristic as outlined by federal, state, or local laws. 

#IHC

PandoLogic. Keywords: Registered Nurse (RN), Location: Cayce, SC - 29033 , PL: 604001273