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Overnight Prn Rn Jobs in Lexington, SC (NOW HIRING)

RN

Columbia, SC · On-site

PRN Registered Nurses (RN) Wanted! White Oak Manor of Columbia | Compassion. Dedication. Excellence. Are you a compassionate and skilled Registered Nurse looking to make a real impact in the lives of ...

PRN RN-13 | Peak Behavioral Health | Santa Teresa, New Mexico About the Job: PURPOSE STATEMENT: The Registered Nurse is responsible for providing nursing care to patients. Supervising care treatment ...

Now offering a $10,000 Sign On Bonus for Full Time RNs! * Now hiring Full Time, Part Time and PRN RNs for Day and Night Shift * Weekend +1 option also available Encompass Health: Where Nursing Meets ...

Now Hiring Full Time, Part Time and PRN RNs for Day Shift and Night Shift * CRRN Position Available Encompass Health: Where Nursing Meets Heart, Home, and Healing Are you seeking a nursing career ...

Registered Nurse Career Opportunity * $10,000 Sign on Bonus for Full Time RNs! * Now Hiring Full Time, Part Time and PRN RNs for Day Shift and Night Shift Encompass Health: Where Nursing Meets Heart ...

PRN Healthcare is seeking a travel nurse RN Intermediate Care for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: Intermediate Care * Discipline: RN * Start Date: 08/17 ...

PRN Healthcare is seeking a travel nurse RN OR - Operating Room for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: OR - Operating Room * Discipline: RN * Start Date: 09 ...

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TNAA TotalMed RN is seeking a travel nurse RN Intermediate Care for a travel nursing job in ... TotalMed specializes in recruiting and placing healthcare professionals in travel, PRN, and ...

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TNAA TotalMed RN is seeking a travel nurse RN Electrophysiology Lab for a travel nursing job in ... TotalMed specializes in recruiting and placing healthcare professionals in travel, PRN, and ...

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PRN Healthcare is seeking a travel nurse RN Electrophysiology Lab for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: Electrophysiology Lab * Discipline: RN * Start Date ...

TNAA TotalMed RN is seeking a travel nurse RN Cardiac Cath Lab for a travel nursing job in Columbia ... TotalMed specializes in recruiting and placing healthcare professionals in travel, PRN, and ...

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PRN Healthcare is seeking a travel nurse RN Cardiac Cath Lab for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: Cardiac Cath Lab * Discipline: RN * Start Date: 08/31 ...

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Overnight Prn Rn information

See Lexington, SC salary details

$16

$31

$46

How much do overnight prn rn jobs pay per hour?

As of Aug 12, 2026, the average hourly pay for overnight prn rn in Lexington, SC is $31.22, according to ZipRecruiter salary data. Most workers in this role earn between $24.90 and $36.01 per hour, depending on experience, location, and employer.

What is an overnight PRN RN?

An Overnight PRN RN is a registered nurse who works as needed (PRN, or 'pro re nata') during overnight shifts, rather than having a regular, set schedule. These nurses fill in for staff shortages or increased patient needs, often covering night shifts in hospitals, clinics, or long-term care facilities. The PRN status gives them flexibility in choosing shifts, but work hours can vary depending on the employer’s staffing requirements. They are responsible for providing patient care, administering medications, and monitoring patient status during nighttime hours.

What is the difference between Overnight Prn Rn vs Per Diem Rn?

AspectOvernight Prn RnPer Diem Rn
CredentialsRegistered Nurse (RN) license, possibly additional certifications for overnight careRegistered Nurse (RN) license, with similar certification requirements
Work EnvironmentHospitals, nursing homes, or clinics during overnight shiftsVaried settings, including hospitals, clinics, or home health, with flexible scheduling
Employment TypeOn-call, PRN (as needed), often overnight shiftsPer diem, as-needed basis, including overnight shifts

Overnight Prn RNs typically work scheduled overnight shifts on an as-needed basis, often in hospitals or long-term care facilities. Per Diem RNs also work on an as-needed basis but may have more flexible scheduling across various settings. Both roles require RN licensure and similar certifications, but the main difference lies in scheduling and employment structure.

What are the key skills and qualifications needed to thrive as an overnight PRN RN?

To thrive as an Overnight PRN RN, you need a current RN license, solid clinical skills, and experience in acute or long-term care settings. Familiarity with electronic health records (EHRs), medication administration systems, and shift-reporting tools is critical. Strong organizational skills, adaptability, and the ability to work independently are important soft skills for managing patient care during night shifts. These qualifications ensure safe, efficient, and consistent patient care, even during off-hours when resources may be limited.

What are some common challenges faced by overnight PRN RNs, and how can they be managed?

Overnight PRN RNs often encounter challenges such as adjusting to irregular sleep schedules, managing limited onsite resources, and handling urgent situations with reduced staff. To manage these, it's important to establish a consistent sleep routine, communicate effectively with the day team during shift changes, and stay organized to prioritize patient care efficiently. Collaborating closely with the on-call team and leveraging available protocols can also help ensure quality care during overnight hours.
What are the most commonly searched types of Prn Rn jobs in Lexington, SC? The most popular types of Prn Rn jobs in Lexington, SC are:
What cities near Lexington, SC are hiring for Overnight Prn Rn jobs? Cities near Lexington, SC with the most Overnight Prn Rn job openings:

Per diem

Re-posted 23 days ago


Job description

Join Our Caring Team! PRN Registered Nurses (RN) Wanted!
White Oak Manor of Columbia | Compassion. Dedication. Excellence.

Are you a compassionate and skilled Registered Nurse looking to make a real impact in the lives of others—on a flexible schedule? We want YOU to join our exceptional team as a PRN RN at our warm and welcoming Long Term Care Facility!

Why You'll Love Working With Us:
Make a difference every day in the lives of our residents
Flexible scheduling that fits your life
Supportive leadership and an amazing team environment
Gain valuable experience in long term and geriatric care
A workplace where your skills and heart truly matter

What You'll Do:

  • Deliver top-notch nursing care to our residents

  • Monitor health status and respond to changes quickly and compassionately

  • Collaborate with physicians, CNAs, and care teams

  • Ensure residents feel safe, respected, and cared for

We’re Looking For:
A current RN license in good standing
A passion for elderly care
Strong clinical and communication skills
Dependable, flexible, and team-oriented attitude

Whether you’re looking to pick up extra shifts or want a flexible schedule to match your lifestyle, this is your opportunity to join a facility that feels like family and treats their team like gold.

Apply today and become a vital part of our caring community!

Ready to make a difference?
We can’t wait to meet you!