1

Overnight Prn Rn Jobs in Lexington, SC (NOW HIRING)

PRN Registered Nurses (RN) Wanted! White Oak Manor of Columbia | Compassion. Dedication. Excellence. Are you a compassionate and skilled Registered Nurse looking to make a real impact in the lives of ...

Now offering a $10,000 Sign On Bonus for Full Time RNs! * Now hiring Full Time, Part Time and PRN RNs for Day and Night Shift * Weekend +1 option also available Encompass Health: Where Nursing Meets ...

Registered Nurse Career Opportunity * $10,000 Sign on Bonus for Full Time RNs! * Now Hiring Full Time, Part Time and PRN RNs for Day Shift and Night Shift Encompass Health: Where Nursing Meets Heart ...

Now Hiring Full Time, Part Time and PRN RNs for Day Shift and Night Shift * CRRN Position Available Encompass Health: Where Nursing Meets Heart, Home, and Healing Are you seeking a nursing career ...

PRN Healthcare is seeking a travel nurse RN Intermediate Care for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: Intermediate Care * Discipline: RN * Start Date: 09/07 ...

PRN Healthcare is seeking a travel nurse RN OR - Operating Room for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: OR - Operating Room * Discipline: RN * Start Date: 09 ...

PRN Healthcare is seeking a travel nurse RN Cardiac Stepdown for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: Cardiac Stepdown * Discipline: RN * Start Date: 09/14 ...

Travel MS/Tele RN

Columbia, SC · On-site

$1.6K - $2.2K/wk

PRN Healthcare is seeking a travel nurse RN Med Surg / Telemetry for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: Med Surg / Telemetry * Discipline: RN * Start Date ...

Travel MS/Tele RN

Columbia, SC · On-site

$1.6K - $2.2K/wk

PRN Healthcare is seeking a travel nurse RN Med Surg / Telemetry for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: Med Surg / Telemetry * Discipline: RN * Start Date ...

Travel MS/Tele RN

Columbia, SC · On-site

$1.6K - $2.2K/wk

PRN Healthcare is seeking a travel nurse RN Med Surg / Telemetry for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: Med Surg / Telemetry * Discipline: RN * Start Date ...

PRN Healthcare is seeking a travel nurse RN Cardiac Stepdown for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: Cardiac Stepdown * Discipline: RN * Start Date: 09/14 ...

Travel MS/Tele RN

Columbia, SC · On-site

$1.6K - $2.2K/wk

PRN Healthcare is seeking a travel nurse RN Med Surg / Telemetry for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: Med Surg / Telemetry * Discipline: RN * Start Date ...

Travel MS/Tele RN

Columbia, SC · On-site

$1.6K - $2.2K/wk

TNAA TotalMed RN is seeking a travel nurse RN Med Surg / Telemetry for a travel nursing job in ... TotalMed specializes in recruiting and placing healthcare professionals in travel, PRN, and ...

next page

Showing results 1-20

Overnight Prn Rn information

See Lexington, SC salary details

$16

$31

$46

How much do overnight prn rn jobs pay per hour?

As of Aug 24, 2026, the average hourly pay for overnight prn rn in Lexington, SC is $31.22, according to ZipRecruiter salary data. Most workers in this role earn between $24.90 and $36.01 per hour, depending on experience, location, and employer.

What is an overnight PRN RN?

An Overnight PRN RN is a registered nurse who works as needed (PRN, or 'pro re nata') during overnight shifts, rather than having a regular, set schedule. These nurses fill in for staff shortages or increased patient needs, often covering night shifts in hospitals, clinics, or long-term care facilities. The PRN status gives them flexibility in choosing shifts, but work hours can vary depending on the employer’s staffing requirements. They are responsible for providing patient care, administering medications, and monitoring patient status during nighttime hours.

What are the key skills and qualifications needed to thrive as an overnight PRN RN?

To thrive as an Overnight PRN RN, you need a current RN license, solid clinical skills, and experience in acute or long-term care settings. Familiarity with electronic health records (EHRs), medication administration systems, and shift-reporting tools is critical. Strong organizational skills, adaptability, and the ability to work independently are important soft skills for managing patient care during night shifts. These qualifications ensure safe, efficient, and consistent patient care, even during off-hours when resources may be limited.

What are some common challenges faced by overnight PRN RNs, and how can they be managed?

Overnight PRN RNs often encounter challenges such as adjusting to irregular sleep schedules, managing limited onsite resources, and handling urgent situations with reduced staff. To manage these, it's important to establish a consistent sleep routine, communicate effectively with the day team during shift changes, and stay organized to prioritize patient care efficiently. Collaborating closely with the on-call team and leveraging available protocols can also help ensure quality care during overnight hours.

What is the difference between Overnight Prn Rn vs Per Diem Rn?

AspectOvernight Prn RnPer Diem Rn
CredentialsRegistered Nurse (RN) license, possibly additional certifications for overnight careRegistered Nurse (RN) license, with similar certification requirements
Work EnvironmentHospitals, nursing homes, or clinics during overnight shiftsVaried settings, including hospitals, clinics, or home health, with flexible scheduling
Employment TypeOn-call, PRN (as needed), often overnight shiftsPer diem, as-needed basis, including overnight shifts

Overnight Prn RNs typically work scheduled overnight shifts on an as-needed basis, often in hospitals or long-term care facilities. Per Diem RNs also work on an as-needed basis but may have more flexible scheduling across various settings. Both roles require RN licensure and similar certifications, but the main difference lies in scheduling and employment structure.

What can I do as an overnight prn RN that is not bedside?

An overnight PRN RN can perform tasks such as patient documentation, care coordination, staff training, quality improvement activities, and administrative duties. They may also assist with medication management, patient education, and compliance audits, often working in clinical or office settings outside direct bedside care.

What are the most commonly searched types of Prn Rn jobs in Lexington, SC?

The most popular types of Prn Rn jobs in Lexington, SC are:

What cities near Lexington, SC are hiring for Overnight Prn Rn jobs?

Cities near Lexington, SC with the most Overnight Prn Rn job openings:

PRN Registered Nurse RN Hospice

Columbia, SC • On-site


Pruitthealth Corporation
Health Care and Social Assistance • 10K+ employees

6.1

Company rating: 6.1 out of 10

Based on 132 frontline employees who took The Breakroom Quiz

116th of 243 rated social care providers

People enjoy working here

Recommended by students

Recommended by parents


$83 - $103/hr

Other

Retirement, PTO

Posted 6 days ago


Job description

Job Description - PRN Registered Nurse RN Hospice (2609409)

PRN Registered Nurse RN Hospice - 2609409

Description

REGISTERED NURSE (RN) CASE MANAGER - HOSPICE SERVICES - PRN Available

Join the PruittHealth Hospice family, where the health and safety of our workforce is our top priority! We're not only committed to your career, we're committed to the health and safety of all our patients and nurses. If you’re looking to be a part of a uniquely specialized team of caregivers providing hospice care in the patient’s home or care facility, then now is the time to join one of the leading providers of post-acute care.

PruittHealth Hospice will help you conquer your career goals. At PruittHealth, we are searching for caregivers who are committed to serving our patients with care and compassion, and in return, we are committed to supporting your nursing career through top-of-market pay, flexible schedules, comprehensive health plans, and more.

Investing in Our Employee-Partners with Benefits
  • Top-of-market pay
  • Annual merit increases
  • Paid time off
  • Employee Referral Bonus Program
  • Preceptorship Program and hands-on training
  • 401(k) and profit-sharing plans
Responsibilities
  • Complete evaluations, assessments, and treatments in accordance with policy and the individualized care plan
  • Complete all documentation and records in a timely and accurate manner
  • Follow established policies and procedures as related to the scope of practice
  • Maintain continuity of patient care in a hospice setting

Qualifications

LICENSURE, CERTIFICATION, AND EDUCATIONAL REQUIREMENTS
  • Current, active, and unrestricted Registered Nurse (RN) licensure in the state of practice

Family Makes Us Stronger. Our family, your family, one family. Committed to loving, giving, and caring. United in making a difference.

We are eager to connect with you!

As an Equal Employment Opportunity employer, all qualified applicants will receive consideration without regard to race, color, religion, sex, national origin, disability, or veteran status.

For Florida Job Postings Only:

For more information regarding Florida’s Care Provider Background Screening Clearinghouse Education and Awareness, please visit https://info.flclearinghouse.com

#J-18808-Ljbffr

PruittHealth logo

About PruittHealth

Sourced by ZipRecruiter

PruittHealth will help you conquer your career goals. At PruittHealth, we are searching for nurses who are committed to serving our residents with care and compassion, and in return, we are committed to supporting your nursing career through annual merit increases, career growth programs, preceptorship, and more.

Industry

Health care and social assistance

Company size

10,000+ Employees

Headquarters location

Norcross, GA, US

Year founded

1969

Social media


What PruittHealth employees say

Pay

Benefits

Hours and flexibility

Workplace

Get the full story on Breakroom