ZipRecruiter

Log In

1

Overnight Prn Rn Jobs in Lexington, SC (NOW HIRING)

TNAA TotalMed RN

Travel OR RN

Columbia, SC · On-site

TNAA TotalMed RN is seeking a travel nurse RN OR - Operating Room for a travel nursing job in ... TotalMed specializes in recruiting and placing healthcare professionals in travel, PRN, and ...

New

PRN Healthcare

Travel ECMO Specialist RN

Columbia, SC · On-site

$1.8K - $2.4K/wk

PRN Healthcare is seeking a travel nurse RN CVICU for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: CVICU * Discipline: RN * Start Date: 08/31/2026 * Duration: 13 ...

TNAA TotalMed RN

Travel LTAC ICU RN

Columbia, SC · On-site

$1.5K - $2.0K/wk

TNAA TotalMed RN is seeking a travel nurse RN Long Term Acute Care for a travel nursing job in ... TotalMed specializes in recruiting and placing healthcare professionals in travel, PRN, and ...

New

TNAA TotalMed RN

Travel LTAC ICU RN

Columbia, SC · On-site

$1.5K - $2.0K/wk

TNAA TotalMed RN is seeking a travel nurse RN Long Term Acute Care ICU - Intensive Care Unit for a ... TotalMed specializes in recruiting and placing healthcare professionals in travel, PRN, and ...

New

Summit BHC

RN- PRN

Peak, SC

RN- PRN | Peak Behavioral Health | Santa Teresa, New Mexico About the Job: PURPOSE STATEMENT: The Registered Nurse is responsible for providing nursing care to patients. Supervising care treatment ...

Summit BHC

RN (PRN)

Peak, SC · On-site

RN (PRN) | Peak Behavioral Health | Santa Teresa, New Mexico About the Job: PURPOSE STATEMENT: The Registered Nurse is responsible for providing nursing care to patients. Supervising care treatment ...

previous pagenext page

Showing results 21-40

All JobsPrn Rn JobsOvernight Prn Rn JobsOvernight Prn Rn Jobs in Lexington, SC

Overnight Prn Rn information

See Lexington, SC salary details

$16

$31

$46

How much do overnight prn rn jobs pay per hour?

As of Aug 13, 2026, the average hourly pay for overnight prn rn in Lexington, SC is $31.22, according to ZipRecruiter salary data. Most workers in this role earn between $24.90 and $36.01 per hour, depending on experience, location, and employer.

What is an overnight PRN RN?

An Overnight PRN RN is a registered nurse who works as needed (PRN, or 'pro re nata') during overnight shifts, rather than having a regular, set schedule. These nurses fill in for staff shortages or increased patient needs, often covering night shifts in hospitals, clinics, or long-term care facilities. The PRN status gives them flexibility in choosing shifts, but work hours can vary depending on the employer’s staffing requirements. They are responsible for providing patient care, administering medications, and monitoring patient status during nighttime hours.

What is the difference between Overnight Prn Rn vs Per Diem Rn?

AspectOvernight Prn RnPer Diem Rn
CredentialsRegistered Nurse (RN) license, possibly additional certifications for overnight careRegistered Nurse (RN) license, with similar certification requirements
Work EnvironmentHospitals, nursing homes, or clinics during overnight shiftsVaried settings, including hospitals, clinics, or home health, with flexible scheduling
Employment TypeOn-call, PRN (as needed), often overnight shiftsPer diem, as-needed basis, including overnight shifts

Overnight Prn RNs typically work scheduled overnight shifts on an as-needed basis, often in hospitals or long-term care facilities. Per Diem RNs also work on an as-needed basis but may have more flexible scheduling across various settings. Both roles require RN licensure and similar certifications, but the main difference lies in scheduling and employment structure.

What are the key skills and qualifications needed to thrive as an overnight PRN RN?

To thrive as an Overnight PRN RN, you need a current RN license, solid clinical skills, and experience in acute or long-term care settings. Familiarity with electronic health records (EHRs), medication administration systems, and shift-reporting tools is critical. Strong organizational skills, adaptability, and the ability to work independently are important soft skills for managing patient care during night shifts. These qualifications ensure safe, efficient, and consistent patient care, even during off-hours when resources may be limited.

What are some common challenges faced by overnight PRN RNs, and how can they be managed?

Overnight PRN RNs often encounter challenges such as adjusting to irregular sleep schedules, managing limited onsite resources, and handling urgent situations with reduced staff. To manage these, it's important to establish a consistent sleep routine, communicate effectively with the day team during shift changes, and stay organized to prioritize patient care efficiently. Collaborating closely with the on-call team and leveraging available protocols can also help ensure quality care during overnight hours.
What are the most commonly searched types of Prn Rn jobs in Lexington, SC? The most popular types of Prn Rn jobs in Lexington, SC are:
What cities near Lexington, SC are hiring for Overnight Prn Rn jobs? Cities near Lexington, SC with the most Overnight Prn Rn job openings:
Overnight Prn Rn jobs near you

Hospice Registered Nurse (RN) - PRN

Interim HealthCare of the Midlands

Cayce, SC • On-site

$38 - $41.30/hr

Full-time

Retirement

Posted 8 days ago

Job description

It’s been said that people will forget what you say and what you do, but never how you make them feel. Hospice nurses are special in that they bring not only strong clinical skills but also a heartfelt commitment to ensuring that patients and their families receive comfort, understanding, and unwavering support during one of life's most meaningful transitions. We are seeking a compassionate and experienced Hospice Registered Nurse (RN) who is dedicated to leading with empathy, clinical excellence, and a deep respect for patient dignity. In this vital role, you will deliver exceptional, patient-centered end-of-life care that honors everyone's journey.

Guided by our mission to honor God through the enrichment of human life, Interim HealthCare has been a trusted leader in home health and hospice services across South Carolina since 1979 and is proud to be recognized as a 9x Top Workplace. We believe exceptional care begins with supported nurses, and we foster an environment where clinicians are respected, empowered, and equipped to do meaningful work—if you’re ready to make a lasting difference in patients’ lives, we invite you to join our team.

Why You’ll Love Working with Interim 

As a PRN Hospice Registered Nurse (RN) with Interim, you’ll enjoy:

  • Competitive compensation ranging from $38.00 - $41.30/ hour DOE, plus mileage reimbursement
  • Flexible scheduling that supports true work-life balance and autonomy
  • Dedicated 1:1 patient care, allowing you to focus on quality care, not volume
  • 401(k) with employer match to help you plan confidently for the future
  • Support for your growth and well-being, including free CEUs, tuition assistance, and fitness reimbursement

What You’ll Do 

As a PRN Hospice Registered Nurse (RN), you will:

  • Completes an initial/comprehensive assessment of the patient/family to determine hospice needs.
  • Completes ongoing assessments of the patient’s physical status and the psycho-social status of the patient/family.
  • Initiates and develops a plan of care in collaboration with the IDG, the patient/family, and the physician.
  • Makes necessary revisions to the IDG plan of care as the patient’s/family’s status and needs change.
  • Primarily responsible for the coordination of care among IDG members and other providers external to the IDG to ensure the continuous assessment of the patient/family needs, as well as the implementation of the IDG plan of care to guide the delivery of services and achieve the goals of hospice care.
  • Evaluates and coordinates the need for services provided to the patient/family in accordance with the IDG plan of care.
  • Administers medications and treatments as prescribed by the physician in accordance with nursing standards of practice.
  • Provides education and interventions to support the effective management of the patient’s pain and other physical symptoms as well as assesses the patient/family’s response to intervention and treatment

What You’ll Need 

  • Graduate of an accredited Registered Nurse (RN) program 
  • Active South Carolina RN license or Compact License 
  • Minimum one year of nursing experience 
  • Hospice experience preferred 

Apply Today 

If you are a Hospice Registered Nurse (RN) looking for a rewarding Hospice opportunity in Columbia, SC, we encourage you to apply and join a compassionate, patient focused team.  

Interim HealthCare is an equal opportunity employer that is committed to diversity and inclusion in the workplace. We prohibit discrimination and harassment of any kind based on race, color, sex, religion, sexual orientation, national origin, disability, genetic information, pregnancy, or any other protected characteristic as outlined by federal, state, or local laws. 

#IHC

PandoLogic. Keywords: Registered Nurse (RN), Location: Cayce, SC - 29033 , PL: 604001273