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Weekend Prn Rn Jobs in Lancaster, SC (NOW HIRING)

PRN Healthcare

Travel Medical Surgical RN

Lancaster, SC · On-site

PRN Healthcare is seeking a travel nurse RN Med Surg for a travel nursing job in Lancaster, South Carolina. & Requirements * Specialty: Med Surg * Discipline: RN * Start Date: 09/08/2026 * Duration ...

MUSC

Registered Nurse | Endoscopy | PRN

Lancaster, SC · On-site

... PRN Cost Center CC001483 LAN - Endoscopy (LMC) Pay Rate Type Hourly Pay Grade Health-27 Scheduled Weekly Hours 12 Work Shift The Registered Nurse reports to the Nurse Manager. Under general ...

Aveanna Healthcare

Registered Nurse (RN)

Monroe, NC · On-site

Registered Nurse - RN We have 2 patients for you to choose from in Monroe! We are hiring Full Time ... Flexible scheduling- full-time, part-time, or PRN. Days, nights, and weekend shifts- we will work ...

Aveanna Healthcare

Registered Nurse (Rn)

Fort Mill, SC · On-site

Registered Nurse - RN $1,000 Sign on Bonus Schedule: Sunday-Saturday 7:00AM - 3:00PM Location ... Flexible scheduling- full-time, part-time, or PRN. Days, nights, and weekend shifts- we will work ...

Phenom People

RN Med Surg PRN Days

Fort Mill, SC · On-site

RN Med Surg PRN Days This role provides direct clinical patient care. The role will assume responsibility for assessing, planning, implementing direct clinical care to assigned patients on a per ...

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Weekend Prn Rn information

See Lancaster, SC salary details

$16

$31

$45

How much do weekend prn rn jobs pay per hour?

As of Sep 2, 2026, the average hourly pay for weekend prn rn in Lancaster, SC is $31.11, according to ZipRecruiter salary data. Most workers in this role earn between $24.81 and $35.87 per hour, depending on experience, location, and employer.

What is a Weekend PRN RN?

A Weekend PRN RN (As Needed Registered Nurse) is a nursing position where the nurse works primarily on weekends and on an as-needed basis. These roles are typically found in hospitals, nursing homes, and healthcare facilities that require additional weekend staffing. PRN nurses do not usually have a set schedule and may be called to fill in for staff shortages. This role offers flexibility but may not guarantee a certain number of hours. Weekend PRN RNs must still meet licensing and certification requirements like full-time nurses.

What are the typical shift expectations and workload for a Weekend PRN RN?

Weekend PRN RN positions usually require nurses to work flexible hours on Saturdays and Sundays, with potential opportunities for additional shifts based on staffing needs. The workload can vary each weekend, depending on patient census and acuity, so adaptability is important. These roles often involve collaborating with a leaner weekend team, requiring strong teamwork and autonomy. While you may not have a set schedule every week, PRN positions can offer valuable hands-on experience and are ideal for nurses seeking flexibility or supplemental income.

What are the key skills and qualifications needed to thrive in the Weekend PRN RN position, and why are they important?

To thrive as a Weekend PRN RN, you need a current RN license, strong clinical assessment abilities, and experience in acute or long-term care settings. Familiarity with electronic health record (EHR) systems, medication administration protocols, and facility-specific safety procedures is important. Flexibility, excellent communication, and the ability to work independently are valuable soft skills for managing varied shifts and patient needs. These competencies ensure that you can provide high-quality care and respond effectively to weekend staffing and patient demands.

Do PRN registered nurses have to work weekends?

PRN registered nurses are scheduled on an as-needed basis and are not typically required to work weekends unless assigned to weekend shifts. Their work schedule depends on the facility's staffing needs and the nurse's availability, often offering flexibility. However, some PRN positions may include weekend shifts if the facility requires coverage during those times.

What job categories do people searching Weekend Prn Rn jobs in Lancaster, SC look for?

The top searched job categories for Weekend Prn Rn jobs in Lancaster, SC are:

What cities near Lancaster, SC are hiring for Weekend Prn Rn jobs?

Cities near Lancaster, SC with the most Weekend Prn Rn job openings:

Weekend Prn Rn jobs near you
Infographic showing various Weekend Prn Rn job openings in Lancaster, SC as of August 2026, with employment types broken down into 1% As Needed, 67% Full Time, 29% Part Time, 2% Contract, and 1% Nights. Highlights an 94% Physical, 1% Hybrid, and 5% Remote job distribution, with an average salary of $64,702 per year, or $31.1 per hour.

Travel Nurse RN - ED - Emergency Department

TNAA TotalMed RN

Rock Hill, SC • On-site

Contractor

Medical, Dental, Vision, Retirement

Posted 21 days ago

Job description

TNAA TotalMed RN is seeking a travel nurse RN ED - Emergency Department for a travel nursing job in Rock Hill, South Carolina.

Job Description & Requirements
  • Specialty: ED - Emergency Department
  • Discipline: RN
  • Start Date: 09/28/2026
  • Duration: 13 weeks
  • 36 hours per week
  • Shift: 12 hours, nights
  • Employment Type: Travel

We're looking for Emergency Room RNs for an immediate travel nurse opening in Rock Hill, SC. The right RN should have 1-2 years recent acute care experience. Read below for more requirements. 
As an ER Travel Nurse, you will work with a diverse team of caregivers to appropriately evaluate, triage and implement care using correct procedures and physician instructions. RNs should have experience and skill caring for patients in a fast-paced, urgent and emergency environment. 
Emergency Room RNs will perform minor medical operations, advise patients and family on illnesses or injuries, and plan long-term care needs. Other responsibilities as an ER Travel Nurse include documenting medical history, checking for any allergies patients might have, obtaining patient vital signs, and monitoring patients' emotional and physical well-being. 
As an ER Travel Nurse, you should be prepared to perform the following tasks:

  • Provide basic bedside care.
  • Clean and bandage wounds.
  • Provide IV therapy.
  • Maintain supplies and medical equipment.
  • Report suspected abuse to appropriate agencies.

ER Travel Nurses should be able to stand and walk for long periods of time, as well as bend, lean and stoop without difficulty. RNs should be able to easily lift 20 pounds. Moving or lifting of patients may require lifting of up to 50 pounds at times. Because of the fast-paced environment, Emergency Room RNs must possess good skills for coping with stress and be able to relate to people of all ages and backgrounds.


Requirements*: ACLS, BLS, PALS, CPI, NIH, 2 Years
* Additional certifications may be required before beginning an assignment.

TotalMed Travel Job ID #1438608. Pay package is based on 12 hour shifts and 36 hours per week (subject to confirmation) with tax-free stipend amount to be determined. Posted job title: Emergency Room - ER RN - Travel Nurse

About TNAA TotalMed RN

TotalMed is a Top Ten, travel nursing and healthcare staffing agency with the mission of igniting purpose in healthcare. The organization staffs nurses, therapists, pharmacists, and other clinicians of all specialties in all 50 states. They offer local and travel jobs and match caregivers with the right organization to assist both facilities and patients. As an organization, they focus on putting highly-skilled staff into facilities to ensure adequate staffing for a better patient experience.


TotalMed specializes in recruiting and placing healthcare professionals in travel, PRN, and permanent positions across the country in Nursing and Allied Health. Throughout 2020, the organization filled roles at even the most short-staffed facilities during the most challenging time in healthcare. By matching the right travel healthcare professional with the right organization, TotalMed continues to offer a lifeline to facilities and their patients.

Benefits
  • Weekly pay
  • Guaranteed Hours
  • Continuing Education
  • 401k retirement plan
  • Sick pay
  • Wellness and fitness programs
  • Referral bonus
  • Employee assistance programs
  • Medical benefits
  • Dental benefits
  • Vision benefits
  • Benefits start day 1
Travel Nurse Across America logo

About Travel Nurse Across America

Sourced by ZipRecruiter

Travel Nurse Across America (TNAA) is a leading healthcare staffing firm headquartered in North Little Rock, Arkansas, USA. Their primary focus lies within the healthcare industry, specializing in providing travel nurses for medical facilities across the country. Founded in 1999, TNAA has thrived over the years by maintaining an unwavering dedication to quality service, reliability, and personalized care for both the clients and the teams they contract. Their mission is driven by their commitment to improve the lives of the patients they serve by ensuring they're provided with the most highly skilled, caring, and dedicated healthcare professionals.

Industry

Recruiting and staffing services and health care and social assistance

Company size

201 - 500 Employees

Headquarters location

North Little Rock, AR, US

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