ZipRecruiter

Log In

1

Variant Analyst Jobs (NOW HIRING)

Massgeneralbrigham

Computational Associate

Boston, MA · On-site

Experience analyzing genetic and genomic data, such as genome-wide association studies (GWAS) or rare variant analysis (Preferred but not required) Strong programming skills (e.g., R, Python ...

Instacart

Senior Security Engineer, Infrastructure

$117K - $160K/yr

Lead investigations, root-cause incidents and findings, and drive variant analysis across the codebase to make sure a class of bug is gone - not just one instance. * Coach and mentor engineers across ...

Astreya

RMA Program Manager

Santa Clara, CA

$98K - $154K/yr

Experience with process intelligence platforms (e.g., process mining tools) for workflow discovery and variant analysis. * Familiarity with AI-assisted case management and Agent-Assist tooling ...

Astreya

RMA Program Manager

Santa Clara, CA · On-site

$98K - $154K/yr

Experience with process intelligence platforms (e.g., process mining tools) for workflow discovery and variant analysis. * Familiarity with AI-assisted case management and Agent-Assist tooling ...

next page

Showing results 1-20

All JobsVariant Analyst Jobs

Variant Analyst information

See salary details

$31K

$73.3K

$130K

How much do variant analyst jobs pay per year?

As of Jul 14, 2026, the average yearly pay for variant analyst in the United States is $73,261.00, according to ZipRecruiter salary data. Most workers in this role earn between $52,500.00 and $87,000.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive in the Variant Analyst position, and why are they important?

To thrive as a Variant Analyst, you need a solid background in genetics or molecular biology, experience in data analysis, and a relevant bachelor's or advanced degree. Familiarity with bioinformatics tools such as Variant Call Format (VCF) analysis software, genomic databases, and proficiency in scripting languages like Python or R is highly valued, as is certification in clinical genetics or genomics. Strong attention to detail, analytical thinking, and effective communication skills distinguish top candidates in this field. These skills and qualities ensure accurate variant interpretation, effective cross-functional collaboration, and meaningful contributions to diagnostics or research.

What are the typical daily responsibilities of a Variant Analyst?

A Variant Analyst typically spends their day analyzing genetic sequencing data to identify, classify, and interpret genetic variants of clinical or research significance. They utilize specialized bioinformatics software to process raw data, review scientific literature for evidence supporting variant classification, and document their findings in detailed reports. Collaboration is common, as analysts often work closely with laboratory geneticists, clinicians, and other members of a multidisciplinary team to ensure accurate and relevant results. Staying updated with the latest guidelines and advances in genomics is also an important part of the role.

What is a Variant Analyst job?

A Variant Analyst is a professional who analyzes genetic variations in DNA sequences to identify mutations associated with diseases or traits. They interpret sequencing data, use bioinformatics tools, and contribute to clinical or research-based genetic analyses. Their work helps in diagnosing genetic disorders, guiding treatment decisions, and advancing precision medicine.

More about Variant Analyst jobs
What cities are hiring for Variant Analyst jobs? Cities with the most Variant Analyst job openings:
What are the most commonly searched types of Variant Analyst jobs? The most popular types of Variant Analyst jobs are:
What states have the most Variant Analyst jobs? States with the most job openings for Variant Analyst jobs include:
What job categories do people searching Variant Analyst jobs look for? The top searched job categories for Variant Analyst jobs are:
Variant Analyst jobs near you

Genome Bioinformatics Analyst

UPMC Senior Communities

Pittsburgh, PA • On-site

$29.92 - $51.79/hr

Full-time

Posted 6 days ago

Job description

a { text-decoration: none; color: #464feb; } tr th, tr td { border: 1px solid #e6e6e6; } tr th { background-color: #f5f5f5; }
Join UPMC Presbyterian's Molecular & Genomic Pathology team as a Genome Bioinformatics Analyst and play a key role in advancing precision medicine. In this unique opportunity, you will analyze and interpret next-generation sequencing (NGS) results that directly impact patient care, collaborating with laboratory and clinical experts to ensure the highest standards of diagnostic accuracy. This position is ideal for candidates with a strong background in genetics, molecular biology, or genomic medicine who are passionate about translating complex genetic data into meaningful clinical insights. Working onsite in Oakland, Pittsburgh, Monday through Friday daylight hours, you'll contribute to variant interpretation, knowledge curation, clinical test development, and innovative research initiatives while continuously expanding your expertise in the rapidly evolving field of genomic diagnostics.
Responsibilities:
  • Designs and executes clinical validation studies to assess diagnostic test performance.
  • Curates disease, gene, and variant knowledge. Helps implement curated knowledge, resources, and workflows into clinical operations.
  • Participates in developmental and clinical research projects, as needed.
  • Maintains SOP documentation of NGS bioinformatics pipeline.
  • In consultation with laboratory staff, physicians and genetic counselors, participates in the review of patient results and develops interpretations for clinical reports.
  • Participates in clinical test development as needed. Evaluates novel platforms and techniques in DNA sequencing, genotyping, and copy-number variation in order to assess suitability for diagnostic application.
  • Maintains data analysis pipelines, monitors quality metrics and analyzes data sets.

Qualifications:
a { text-decoration: none; color: #464feb; } tr th, tr td { border: 1px solid #e6e6e6; } tr th { background-color: #f5f5f5; }
Education
  • PhD in Molecular Biology, Human Genetics, Bioinformatics, Computational Biology, or a related field required.
  • A Master's degree in a related field may be considered with two or more years of relevant experience.

Experience & Knowledge
  • Strong experience with molecular genetics technologies and Next-Generation Sequencing (NGS) required.
  • Clinical diagnostic laboratory experience preferred.
  • Statistical and bioinformatics experience is a plus.
  • Familiarity with genomic databases such as HGMD, ExAC, and 1000 Genomes preferred.
  • Experience with bioinformatics tools, including Samtools, IGV, ANNOVAR, and GATK, as well as file formats such as BED, VCF, FASTQ, and BAM preferred.
  • Strong analytical, critical thinking, and organizational skills.
  • Excellent written and verbal communication skills.
  • Ability to work effectively with interdisciplinary teams, including scientists, physicians, and genetic counselors.
  • Demonstrated professionalism, initiative, and enthusiasm.
  • Ability to thrive in a fast-paced environment while maintaining a high level of accuracy and attention to detail.

UPMC is an Equal Opportunity Employer/Disability/Veteran.

Apply