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Variant Analyst Jobs (NOW HIRING)

Astreya

RMA Program Manager

Santa Clara, CA · On-site

$98K - $154K/yr

Experience with process intelligence platforms (e.g., process mining tools) for workflow discovery and variant analysis. * Familiarity with AI-assisted case management and Agent-Assist tooling ...

Astreya

RMA Program Manager

Santa Clara, CA · On-site

$98K - $154K/yr

Experience with process intelligence platforms (e.g., process mining tools) for workflow discovery and variant analysis. * Familiarity with AI-assisted case management and Agent-Assist tooling ...

E*Pro, Inc.

SAP Business Analyst

Reading, PA

$50.25 - $67.25/hr

SAP Business Analyst Location : Reading, PA Job Type : Permanent Full Time Description: Effective ... MPS, MRP, SOP, Demand Planning - DP, Variant Configuration -VC; BOM, Routings, Work Centers; QM; PI ...

Ambry Genetics

$110K - $114K/yr

The Clinical Genomic Scientist II is highly proficient in variant classification guidelines and in ... analysis Thorough and ongoing knowledge of current theories and principles of human genetics ...

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Variant Analyst information

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$31K

$73.3K

$130K

How much do variant analyst jobs pay per year?

As of Jun 22, 2026, the average yearly pay for variant analyst in the United States is $73,261.00, according to ZipRecruiter salary data. Most workers in this role earn between $52,500.00 and $87,000.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive in the Variant Analyst position, and why are they important?

To thrive as a Variant Analyst, you need a solid background in genetics or molecular biology, experience in data analysis, and a relevant bachelor's or advanced degree. Familiarity with bioinformatics tools such as Variant Call Format (VCF) analysis software, genomic databases, and proficiency in scripting languages like Python or R is highly valued, as is certification in clinical genetics or genomics. Strong attention to detail, analytical thinking, and effective communication skills distinguish top candidates in this field. These skills and qualities ensure accurate variant interpretation, effective cross-functional collaboration, and meaningful contributions to diagnostics or research.

What are the typical daily responsibilities of a Variant Analyst?

A Variant Analyst typically spends their day analyzing genetic sequencing data to identify, classify, and interpret genetic variants of clinical or research significance. They utilize specialized bioinformatics software to process raw data, review scientific literature for evidence supporting variant classification, and document their findings in detailed reports. Collaboration is common, as analysts often work closely with laboratory geneticists, clinicians, and other members of a multidisciplinary team to ensure accurate and relevant results. Staying updated with the latest guidelines and advances in genomics is also an important part of the role.

What is a Variant Analyst job?

A Variant Analyst is a professional who analyzes genetic variations in DNA sequences to identify mutations associated with diseases or traits. They interpret sequencing data, use bioinformatics tools, and contribute to clinical or research-based genetic analyses. Their work helps in diagnosing genetic disorders, guiding treatment decisions, and advancing precision medicine.

More about Variant Analyst jobs
What cities are hiring for Variant Analyst jobs? Cities with the most Variant Analyst job openings:
What are the most commonly searched types of Variant Analyst jobs? The most popular types of Variant Analyst jobs are:
What states have the most Variant Analyst jobs? States with the most job openings for Variant Analyst jobs include:
What job categories do people searching Variant Analyst jobs look for? The top searched job categories for Variant Analyst jobs are:
Variant Analyst jobs near you
Infographic showing various Variant Analyst job openings in the United States as of June 2026, with employment types broken down into 55% Locum Tenens, 7% As Needed, 35% Full Time, 1% Part Time, 1% Nights, and 1% Summer. Highlights an 81% Physical, 8% Hybrid, and 11% Remote job distribution, with an average salary of $73,261 per year, or $35.2 per hour.
Senior Director - Section Lead, Specialized Analytics and Capabilities, ADQC, US

Senior Director - Section Lead, Specialized Analytics and Capabilities, ADQC, US

Genentech, Inc.

South San Francisco, CA • On-site

$205K - $382K/yr

Full-time

Posted 27 days ago

Genentech rating

8.8

Company rating: 8.8 out of 10

Based on 22 frontline employees who took The Breakroom Quiz

10th of 71 rated pharmaceutical

Job description

A healthier future. It's what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That's what makes us Genentech, a member of the Roche Group.
The Opportunity
A Section Lead position for Specialized Analytics and Capabilities (Senior Director-level) is available within the Analytical Development & Quality Control (ADQC) department for US Biologics (PTD). This strategic role requires a collaborative leader with a proven track record in biologics development to provide technical and operational leadership to a high-performance team responsible for the end-to-end analytical characterization of complex biologics and small molecule impurities using advanced tools like MS and NMR spectroscopy. Balancing scientific expertise, business acumen, and customer focus, the successful candidate will drive results in a fast-paced environment, ensure efficient execution, and advance the department's digital and innovation efforts.
Key Responsibilities:
  • Lead, coach, and develop a team of 15-20 comprising of technical leaders and scientists within the Specialized Analytics section of Analytical Development
  • Oversee the strategic, operational, and technical deliverables using combined advanced analytics including MS spectroscopy, hyphenated MS spectroscopy techniques, NMR spectroscopy and other complex analytical technologies
  • Oversee prioritization, resource planning, and execution of specialized analytics support across multiple programs and business needs including biologics characterization and small molecule impurities testing.
  • Drive the MS-based characterization of biologics (mAbs, bispecifics, fusion proteins, ADCs, bioconjugates, etc.) including Sequence variant analysis, Host cell protein analysis and characterization, minor variant characterization, and related advanced characterization work to support a complex biologics pipeline.
  • Provide overarching MS strategy to ensure global regulatory alignment and direct response to health authority inquiries.
  • Drive adoption of digital tools, data strategies, automation, advanced analytics, and innovative workflows within the analytical organization, in line with overall organizational data and digital strategy
  • Authoring of relevant sections in INDs and IMAs
  • Responsible for development and implementation of next-gen analytical tools.
  • Set clear expectations for scientific quality, collaboration, accountability, and innovation.
  • Foster a high-performance culture of learning and continuous improvement that prioritizes scientific rigor, data integrity, knowledge sharing, and cross-functional collaboration.

Who you are
  • PhD in chemistry, biochemistry, biology, or related field with at least 10+ years' experience; or M.S./B.S. with a minimum of 12-15+ years' experience (respectively) in the pharmaceutical/biopharmaceutical industry. 5+ years of managerial experience.
  • Strong understanding of biologics modalities and demonstrated experience with relevant analytical methodologies (HPLC/UPLC, Mass Spectrometry, etc.).
  • In-depth scientific and technical knowledge and experience in the analytical development of biologics.
  • Demonstrated success in building and leading teams, driving operational performance and achieving business growth.
  • Strong business acumen with ability to balance scientific excellence and business priorities
  • Highly motivated and self-driven. Good communication skills, organizational skills, detail orientation. Ability to work effectively in a fast paced, multi-disciplinary environment with various projects and timelines.

Preferred:
  • PhD or Master's degree
  • Large team leadership experience in a complex cross-functional environment
  • Background and experience in product development and commercialization

Relocation benefits are available for this job posting.
The expected salary range for this position based on the primary location of South San Francisco, CA is $205,900 - $382,500. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.
Benefits
Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.
If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

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About Genentech

Sourced by ZipRecruiter

A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work.

Industry

Scientific research and development services

Company size

10,000+ Employees

Headquarters location

South San Francisco, CA, US

Year founded

1976

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