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Clinical Variant Analyst Jobs (NOW HIRING)

Nationwide Children's Hospital

... clinical features. * Maintains accurate and detailed records of variant analysis and interpretation. * Stays up-to-date with the latest research and developments in the field of genomics.

Nationwide Children's Hospital

... variant assessment, including evaluation of published literature and clinical data to provide ... Strong analytical skills and ability to critically read and interpret data from scientific ...

Belay Diagnostics

Clinical Genomics Analyst

Chicago, IL · On-site

$80K - $90K/yr

Evaluate variant function, potential clinical impact and genotype-phenotype relationships using ... Perform quality control of variant and clinical analysis, interpretations and completed reports

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How much do clinical variant analyst jobs pay per hour?

As of Jul 9, 2026, the average hourly pay for clinical variant analyst in the United States is $39.80, according to ZipRecruiter salary data. Most workers in this role earn between $31.49 and $45.67 per hour, depending on experience, location, and employer.

What is the highest paying job in genetics?

In genetics, roles such as genetic counselors, clinical geneticists, and research directors tend to have the highest salaries. Senior positions requiring advanced degrees, certifications, and extensive experience typically offer the highest compensation in the field.

What is a Clinical Variant Analyst?

A Clinical Variant Analyst is a professional who interprets and analyzes genetic variants identified through clinical genetic testing. Their main role is to evaluate DNA sequence changes to determine their significance in relation to health and disease. They collaborate with geneticists, laboratory scientists, and clinicians to classify variants according to established guidelines and help inform patient diagnoses and management. Additionally, Clinical Variant Analysts review scientific literature, use databases, and may contribute to research and quality improvement in genetic testing.

What are some common challenges Clinical Variant Analysts face when interpreting genetic data, and how can they be addressed?

Clinical Variant Analysts often encounter challenges such as distinguishing between benign and pathogenic variants, managing large datasets, and keeping up with rapidly evolving scientific literature. Addressing these challenges requires strong analytical skills, familiarity with bioinformatics tools, and ongoing collaboration with genetic counselors, laboratory directors, and clinicians. Staying current through continuous education and attending case discussions or multidisciplinary meetings also helps analysts provide accurate and clinically relevant interpretations.

What are the key skills and qualifications needed to thrive as a Clinical Variant Analyst, and why are they important?

To thrive as a Clinical Variant Analyst, you need a strong background in genetics, molecular biology, and bioinformatics, typically supported by a relevant degree such as in genetics or molecular biology. Familiarity with next-generation sequencing (NGS) platforms, variant interpretation databases (like ClinVar), and clinical reporting software is commonly required, along with certifications such as ACMG variant interpretation training. Attention to detail, analytical thinking, and effective communication are vital soft skills for accurately interpreting genetic data and collaborating with clinical teams. These skills ensure accurate variant classification and reporting, directly impacting patient diagnosis and care.

What is the highest paying analyst job?

Among analyst roles, senior or specialized positions such as data science managers, financial directors, or clinical research directors tend to have the highest salaries. Clinical Variant Analysts with advanced certifications and experience in genomic data analysis can also command higher compensation, especially in biotech or pharmaceutical industries.

What does a variant analyst do?

A clinical variant analyst examines genetic data to identify and interpret variations in DNA sequences that may be linked to diseases. They analyze sequencing results using bioinformatics tools, review scientific literature, and collaborate with healthcare professionals to determine the clinical significance of genetic variants. This role often requires knowledge of genetics, molecular biology, and proficiency with data analysis software.

What biology jobs pay over $100k?

Clinical Variant Analysts and other specialized genetics professionals can earn over $100,000 annually, especially with advanced degrees, certifications, and experience in genomic analysis, bioinformatics, or laboratory management. High-paying roles often require proficiency with tools like next-generation sequencing and knowledge of genetic databases, typically found in research institutions or biotech companies.
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Clinical Variant Analyst jobs near you
Infographic showing various Clinical Variant Analyst job openings in the United States as of July 2026, with employment types broken down into 1% Locum Tenens, 1% Internship, 86% Full Time, 6% Part Time, 1% Temporary, and 5% Contract. Highlights an 82% Physical, 5% Hybrid, and 13% Remote job distribution, with an average salary of $82,791 per year, or $39.8 per hour.
IGM Clinical Genomics Variant Analyst I

IGM Clinical Genomics Variant Analyst I

Nationwide Children's Hospital

Full-time

Re-posted 20 days ago

Nationwide Children's Hospital rating

6.9

Company rating: 6.9 out of 10

Based on 129 frontline employees who took The Breakroom Quiz

528th of 1,013 rated hospitals

Job description

Overview:



Job Description Summary:


Accurately identifies, classifies, and documents variants following practice guidelines under the direction of the Laboratory Directors and Variant Scientists. Assists with the day-to-day operations of variant assessment, curation, and documentation to accurately identify and classify genomic alterations detected through genomic testing and translational studies.


Job Description:


Essential Functions:

  • Analyzes and interprets genomic data to identify genetic variants that may contribute to disease.
  • Collaborates with other members of the clinical laboratory team to interpret genomic variant relative to patient-specific clinical features.
  • Maintains accurate and detailed records of variant analysis and interpretation.
  • Stays up-to-date with the latest research and developments in the field of genomics.
  • Communicates findings to clinical laboratory directors.
  • Participates in quality control and quality assurance activities to ensure accurate and reliable results.


Education Requirement:

Bachelor's Degree in molecular genetics, human genetics, genetic counseling, molecular pathology, or computational field, required.


Licensure Requirement:

(not specified)


Certifications:

(not specified)


Skills:

  • Strong analytical skills and ability to critically read and interpret data from scientific publications.
  • Ability to do technical writing, as well as good communication and computer skills.
  • Good organizational and interpersonal skills.
  • Ability to initiate and work on several projects at a time with minimal supervision; motivation to follow through to completion while adhering to deadlines and maintaining accurate records.


Experience:

  • Three years of experience in Laboratory Genetics, Cancer Genomics, Computational biology or a related field, required.
  • Experience in variant analysis, preferred.


Physical Requirements:

OCCASIONALLY: Bend/twist, Climb stairs/ladder, Cold Temperatures, Flexing/extending of neck, Fume /Gases /Vapors, Hand use: grasping, gripping, turning, Hot Temperatures, Lifting / Carrying: 11-20 lbs, Loud Noises, Reaching above shoulder, Repetitive hand/arm use, Squat/kneel, Standing, Walking

FREQUENTLY: Color vision, Peripheral vision, Seeing - Far/near

CONTINUOUSLY: Audible speech, Computer skills, Decision Making, Depth perception, Hearing acuity, Interpreting Data, Lifting / Carrying: 0-10 lbs, Problem solving, Sitting


Additional Physical Requirements performed but not listed above:

The position requires excellent manual dexterity, good visual acuity and hearing, and excellent communication skills as well as a better-than-average ability to write. Physical activities frequently include sitting, talking on the phone or in person, utilizing fine motor skills, standing.




"The above list of duties is intended to describe the general nature and level of work performed by individuals assigned to this classification. It is not to be construed as an exhaustive list of duties performed by the individuals so classified, nor is it intended to limit or modify the right of any supervisor to assign, direct, and control the work of employees under their supervision. EOE M/F/Disability/Vet"

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About Nationwide Children's Hospital

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Nationwide Children's Hospital, established in 1894, is a leading pediatric healthcare system based in Columbus, Ohio, United States. They serve as a primary pediatric network, providing wellness, preventive, diagnostic, treatment, and rehabilitative care for infants, children, adolescents, and adults with congenital disease. Being the third-largest pediatric hospital in the nation, Nationwide Children's Hospital prides itself on its relentless commitment to children and their families, driven by their core values of respect, integrity, determination, empathy, and solidarity. The institution's comprehensive mission is to enhance the health of children by providing high-quality, family-centered care, conducting groundbreaking research, advocating for pediatric health, and training top healthcare professionals.

Industry

Hospitals

Company size

10,000+ Employees

Headquarters location

Columbus, OH, US

Year founded

1892

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