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Clinical Variant Analyst Jobs (NOW HIRING)

... clinical features. * Maintains accurate and detailed records of variant analysis and interpretation. * Stays up-to-date with the latest research and developments in the field of genomics.

Demonstrated ability to critically evaluate scientific literature and apply findings to clinical variant interpretation. Core Skills: * Advanced Analytical & Critical Thinking - Interprets complex ...

... variant assessment, including evaluation of published literature and clinical data to provide ... Strong analytical skills and ability to critically read and interpret data from scientific ...

$112K - $120K/yr

Responsibilities include variant analysis of diagnostic molecular genetic test results; evaluation of published literature, clinical data and review of both functional and in silico data to provide ...

Analysis (30%): analyzing clinical genomics data, selecting variants for curation/confirmation, variant nomenclature following HGVS guidelines * Other (20%): may involve clinical report drafting ...

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Clinical Variant Analyst information

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How much do clinical variant analyst jobs pay per hour?

As of May 28, 2026, the average hourly pay for clinical variant analyst in the United States is $39.80, according to ZipRecruiter salary data. Most workers in this role earn between $31.49 and $45.67 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Clinical Variant Analyst, and why are they important?

To thrive as a Clinical Variant Analyst, you need a strong background in genetics, molecular biology, and bioinformatics, typically supported by a relevant degree such as in genetics or molecular biology. Familiarity with next-generation sequencing (NGS) platforms, variant interpretation databases (like ClinVar), and clinical reporting software is commonly required, along with certifications such as ACMG variant interpretation training. Attention to detail, analytical thinking, and effective communication are vital soft skills for accurately interpreting genetic data and collaborating with clinical teams. These skills ensure accurate variant classification and reporting, directly impacting patient diagnosis and care.

What are some common challenges Clinical Variant Analysts face when interpreting genetic data, and how can they be addressed?

Clinical Variant Analysts often encounter challenges such as distinguishing between benign and pathogenic variants, managing large datasets, and keeping up with rapidly evolving scientific literature. Addressing these challenges requires strong analytical skills, familiarity with bioinformatics tools, and ongoing collaboration with genetic counselors, laboratory directors, and clinicians. Staying current through continuous education and attending case discussions or multidisciplinary meetings also helps analysts provide accurate and clinically relevant interpretations.

What is a Clinical Variant Analyst?

A Clinical Variant Analyst is a professional who interprets and analyzes genetic variants identified through clinical genetic testing. Their main role is to evaluate DNA sequence changes to determine their significance in relation to health and disease. They collaborate with geneticists, laboratory scientists, and clinicians to classify variants according to established guidelines and help inform patient diagnoses and management. Additionally, Clinical Variant Analysts review scientific literature, use databases, and may contribute to research and quality improvement in genetic testing.
More about Clinical Variant Analyst jobs
What cities are hiring for Clinical Variant Analyst jobs? Cities with the most Clinical Variant Analyst job openings:
What states have the most Clinical Variant Analyst jobs? States with the most job openings for Clinical Variant Analyst jobs include:
Infographic showing various Clinical Variant Analyst job openings in the United States as of May 2026, with employment types broken down into 100% Full Time. Highlights an 60% In-person, and 40% Remote job distribution, with an average salary of $82,791 per year, or $39.8 per hour.
IGM Clinical Genomics Variant Analyst I

Full-time

Posted 9 days ago


Nationwide Children's Hospital rating

7.1

Company rating: 7.1 out of 10

Based on 126 frontline employees who took The Breakroom Quiz

431st of 989 rated hospitals


Job description

Overview:



Job Description Summary:


Accurately identifies, classifies, and documents variants following practice guidelines under the direction of the Laboratory Directors and Variant Scientists. Assists with the day-to-day operations of variant assessment, curation, and documentation to accurately identify and classify genomic alterations detected through genomic testing and translational studies.


Job Description:


Essential Functions:
  • Analyzes and interprets genomic data to identify genetic variants that may contribute to disease.
  • Collaborates with other members of the clinical laboratory team to interpret genomic variant relative to patient-specific clinical features.
  • Maintains accurate and detailed records of variant analysis and interpretation.
  • Stays up-to-date with the latest research and developments in the field of genomics.
  • Communicates findings to clinical laboratory directors.
  • Participates in quality control and quality assurance activities to ensure accurate and reliable results.

Education Requirement:

Bachelor's Degree in molecular genetics, human genetics, genetic counseling, molecular pathology, or computational field, required.


Licensure Requirement:

(not specified)


Certifications:

(not specified)


Skills:
  • Strong analytical skills and ability to critically read and interpret data from scientific publications.
  • Ability to do technical writing, as well as good communication and computer skills.
  • Good organizational and interpersonal skills.
  • Ability to initiate and work on several projects at a time with minimal supervision; motivation to follow through to completion while adhering to deadlines and maintaining accurate records.

Experience:
  • Three years of experience in Laboratory Genetics, Cancer Genomics, Computational biology or a related field, required.
  • Experience in variant analysis, preferred.

Physical Requirements:

OCCASIONALLY: Bend/twist, Climb stairs/ladder, Cold Temperatures, Flexing/extending of neck, Fume /Gases /Vapors, Hand use: grasping, gripping, turning, Hot Temperatures, Lifting / Carrying: 11-20 lbs, Loud Noises, Reaching above shoulder, Repetitive hand/arm use, Squat/kneel, Standing, Walking

FREQUENTLY: Color vision, Peripheral vision, Seeing - Far/near

CONTINUOUSLY: Audible speech, Computer skills, Decision Making, Depth perception, Hearing acuity, Interpreting Data, Lifting / Carrying: 0-10 lbs, Problem solving, Sitting


Additional Physical Requirements performed but not listed above:

The position requires excellent manual dexterity, good visual acuity and hearing, and excellent communication skills as well as a better-than-average ability to write. Physical activities frequently include sitting, talking on the phone or in person, utilizing fine motor skills, standing.




"The above list of duties is intended to describe the general nature and level of work performed by individuals assigned to this classification. It is not to be construed as an exhaustive list of duties performed by the individuals so classified, nor is it intended to limit or modify the right of any supervisor to assign, direct, and control the work of employees under their supervision. EOE M/F/Disability/Vet"


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About Nationwide Children's Hospital

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Nationwide Children's Hospital, established in 1894, is a leading pediatric healthcare system based in Columbus, Ohio, United States. They serve as a primary pediatric network, providing wellness, preventive, diagnostic, treatment, and rehabilitative care for infants, children, adolescents, and adults with congenital disease. Being the third-largest pediatric hospital in the nation, Nationwide Children's Hospital prides itself on its relentless commitment to children and their families, driven by their core values of respect, integrity, determination, empathy, and solidarity. The institution's comprehensive mission is to enhance the health of children by providing high-quality, family-centered care, conducting groundbreaking research, advocating for pediatric health, and training top healthcare professionals.

Industry

Hospitals

Company size

10,000+ Employees

Headquarters location

Columbus, OH, US

Year founded

1892