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Clinical Variant Analyst Jobs (NOW HIRING)

Lifespan

Clinical Research Assistant

Providence, RI · On-site

Participates in qualitative/quantitative analyses of resultant data. Reviews relevant literature to ... A.) font-variant-numeric: normal; font-variant-east-asian: normal; font-stretch: normal; font-size ...

Lifespan

Clinical Research Assistant

Providence, RI · On-site

Participates in qualitative/quantitative analyses of resultant data. Reviews relevant literature to ... A.) font-variant-numeric: normal; font-variant-east-asian: normal; font-stretch: normal; font-size ...

Baylor Genetics

Clinical Genomic Scientist - WGS

Analysis (30%): analyzing clinical genomics data, selecting variants for curation/confirmation, variant nomenclature following HGVS guidelines. * Other (20%): may involve clinical report drafting ...

Brownhealth

Clinical Research Assistant

Providence, RI · On-site

A.) font-variant-numeric: normal; font-variant-east-asian: normal; font-stretch: normal; font-size ... Analytical skills toparticipate in developing research protocols, perform statistical analyses ...

Tempus

$110K - $114K/yr

The Clinical Genomic Scientist II is highly proficient in variant classification guidelines and in ... analysis Thorough and ongoing knowledge of current theories and principles of human genetics ...

Ambry Genetics

$110K - $114K/yr

The Clinical Genomic Scientist II is highly proficient in variant classification guidelines and in ... analysis Thorough and ongoing knowledge of current theories and principles of human genetics ...

Bionano

Clinical Lab Director

San Diego, CA · On-site

... analytic, analytic, and post-analytic testing processes. * Support compliance with CLIA, CAP ... Working knowledge of ACMG/AMP and related professional guidance for copy number, sequence variant ...

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Clinical Variant Analyst information

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How much do clinical variant analyst jobs pay per hour?

As of Aug 21, 2026, the average hourly pay for clinical variant analyst in the United States is $39.80, according to ZipRecruiter salary data. Most workers in this role earn between $31.49 and $45.67 per hour, depending on experience, location, and employer.

What is a clinical variant analyst?

A Clinical Variant Analyst is a professional who interprets and analyzes genetic variants identified through clinical genetic testing. Their main role is to evaluate DNA sequence changes to determine their significance in relation to health and disease. They collaborate with geneticists, laboratory scientists, and clinicians to classify variants according to established guidelines and help inform patient diagnoses and management. Additionally, Clinical Variant Analysts review scientific literature, use databases, and may contribute to research and quality improvement in genetic testing.

What are the key skills and qualifications needed to thrive as a clinical variant analyst, and why are they important?

To thrive as a Clinical Variant Analyst, you need a strong background in genetics, molecular biology, and bioinformatics, typically supported by a relevant degree such as in genetics or molecular biology. Familiarity with next-generation sequencing (NGS) platforms, variant interpretation databases (like ClinVar), and clinical reporting software is commonly required, along with certifications such as ACMG variant interpretation training. Attention to detail, analytical thinking, and effective communication are vital soft skills for accurately interpreting genetic data and collaborating with clinical teams. These skills ensure accurate variant classification and reporting, directly impacting patient diagnosis and care.

What are some common challenges clinical variant analysts face when interpreting genetic data, and how can they be addressed?

Clinical Variant Analysts often encounter challenges such as distinguishing between benign and pathogenic variants, managing large datasets, and keeping up with rapidly evolving scientific literature. Addressing these challenges requires strong analytical skills, familiarity with bioinformatics tools, and ongoing collaboration with genetic counselors, laboratory directors, and clinicians. Staying current through continuous education and attending case discussions or multidisciplinary meetings also helps analysts provide accurate and clinically relevant interpretations.
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Clinical Variant Analyst jobs near you
Infographic showing various Clinical Variant Analyst job openings in the United States as of August 2026, with employment types broken down into 92% Full Time, and 8% Part Time. Highlights an 92% In-person, and 8% Remote job distribution, with an average salary of $82,791 per year, or $39.8 per hour.

Senior Bioinformatics Scientist, Translational Bioinformatics

Predicine, Inc

Hayward, CA • On-site

Full-time

Posted 4 days ago

Job description

Location: Hayward, CA
Work Arrangement: TBD
Department: Translational Bioinformatics (NGS/Liquid Biopsy)
Employment Type: Full-TimeAbout Predicine

Predicine is a precision oncology company advancing the fight against cancer through cutting-edge genomic technologies and liquid biopsy solutions. We partner with pharmaceutical companies, clinicians, and researchers worldwide to bring next-generation diagnostics from bench to bedside — faster, smarter, and more accessible. Join a team where your work directly impacts patient outcomes and the future of cancer care.

Job Summary

We are seeking a highly motivated senior bioinformatics scientist to support NGS-based liquid biopsy studies and translational bioinformatics programs. The incumbent will analyze cfDNA/cfRNA, tissue, RNA-seq, multi-omics, and clinical data to develop biomarker testing strategies for cancer diagnosis and clinical applications. This is a client-facing scientist role — you'll represent the scientific team in technology meetings with pharmaceutical clients, KOLs, and client data scientists, translating client needs into analysis plans, result interpretation, and follow-up support with a client-success mindset. This is an exciting opportunity to join a fast-growing startup, accelerate your growth, and make a positive, immediate impact on cancer diagnosis and treatment.

What You'll Do

The Senior Bioinformatics Scientist, NGS and Liquid Biopsy will lead bioinformatics analysis in support of NGS-based liquid biopsy studies and translational bioinformatics programs. This role will analyze cfDNA/cfRNA, tumor tissue, RNA-seq, multi-omics, and clinical datasets to develop and refine biomarker testing strategies for cancer diagnosis and clinical applications. Serving as a client-facing scientific partner, the incumbent will represent the scientific team in technology meetings with pharmaceutical clients, KOLs, and client data scientists — translating client needs into analysis plans, interpreting results, and providing ongoing follow-up support with a client-success mindset. The position will also develop and improve computational pipelines, statistical models, and machine-learning approaches for sequencing QC, variant analysis, and study-specific analyses, while coordinating internal and external collaborations, scientific presentations, publications, and mentoring across translational bioinformatics projects.

Key Responsibilities & Time Allocation% of TimeResponsibility35%Bioinformatics Analysis Leadership — Lead bioinformatics analysis for NGS and liquid biopsy studies, including assay development, validation support, interpretation, and biomarker reporting.25%Multi-Omics Data Analysis — Analyze clinical, genomic, transcriptomic, proteomic, and other multi-omics datasets to identify biomarkers, targets, and tumor biology insights.20%Pipeline & Model Development — Develop and improve computational pipelines, statistical models, and machine-learning approaches for sequencing QC, variant analysis, annotation, and study-specific analyses.15%Client-Facing Scientific Partnership — Serve as a client-facing scientific partner in technology meetings, aligning scope, data interpretation, deliverables, and follow-up with clients and KOLs.5%Collaboration & Mentorship — Coordinate internal/external collaborations, scientific presentations, publications, and mentoring for translational bioinformatics projects.


What You Bring

Education


MinimumPreferredLevelMaster's degree with 5+ years of relevant experienceDoctorate (PhD)Field of StudyBioinformatics, Computational Biology, Biostatistics, Genomics, Molecular Biology, Cancer Biology, or related fieldSame fields


Experience


MinimumPreferredWork Experience3+ years post-graduation with hands-on NGS analysis and client-facing collaboration experiencePharmaceutical industry experience; tumor research publications or experience


Required Skills & Qualifications

  • Strong R and/or Python programming skills; familiarity with Unix/Linux and reproducible workflows
  • Hands-on NGS and liquid biopsy analysis experience, including cfDNA/cfRNA, tumor tissue, RNA-seq, or single-cell data
  • Experience with variant analysis, CNV/fusion analysis, MSI/TMB, multi-omics integration, statistics, or machine learning
  • Strong publication or meeting presentation record, with clear scientific writing skills
  • Excellent client-facing communication with pharma clients, KOLs, client data scientists, and internal cross-functional teams

Preferred Skills & Qualifications

  • Pharmaceutical industry experience
  • Tumor research publications or hands-on tumor research experience
Join Us
At Predicine, you won't just analyze data — you'll help translate cutting-edge genomic science into real diagnostic tools that change how cancer is detected and treated. If you're a scientist who thrives at the intersection of deep technical analysis and client partnership, we want to hear from you.

Apply today and help us turn breakthrough science into better patient outcomes.

Predicine is an Equal Opportunity Employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.