Clinical Genomics Scientist
Phoenix, AZ · On-site
The Clinical Genomics Scientist will work closely with Clinical Genomics physician leadership to ... optimize variant analysis performance. * Gene and Variant Curation Contribute to curation ...
Clinical Genomics Scientist
Phoenix, AZ · On-site
The Clinical Genomics Scientist will work closely with Clinical Genomics physician leadership to ... optimize variant analysis performance. * Gene and Variant Curation Contribute to curation ...
... data analysis across all clinical genomics laboratory testing platforms to support accurate variant interpretation and reporting. • Integrates clinical data and literature into report ...
... data analysis across all clinical genomics laboratory testing platforms to support accurate variant interpretation and reporting. • Integrates clinical data and literature into report ...
Manager - Bioinformatics
Tempe, AZ · On-site
$140 - $200/hr
The Manager partners closely with laboratory, clinical, software engineering, IT, quality, and ... Support end-to-end genomic data analysis, including quality control, alignment, variant calling ...
Manager - Bioinformatics
Tempe, AZ · On-site
$140 - $200/hr
The Manager partners closely with laboratory, clinical, software engineering, IT, quality, and ... Support end-to-end genomic data analysis, including quality control, alignment, variant calling ...
Manager - Bioinformatics
Phoenix, AZ · On-site
$150 - $210/hr
The Manager partners closely with laboratory, clinical, software engineering, IT, quality, and ... Support end-to-end genomic data analysis, including quality control, alignment, variant calling ...
Manager - Bioinformatics
Phoenix, AZ · On-site
$150 - $210/hr
The Manager partners closely with laboratory, clinical, software engineering, IT, quality, and ... Support end-to-end genomic data analysis, including quality control, alignment, variant calling ...
Manager - Bioinformatics
Tempe, AZ · On-site
The Manager partners closely with laboratory, clinical, software engineering, IT, quality, and ... Support end-to-end genomic data analysis, including quality control, alignment, variant calling ...
Manager - Bioinformatics
Tempe, AZ · On-site
The Manager partners closely with laboratory, clinical, software engineering, IT, quality, and ... Support end-to-end genomic data analysis, including quality control, alignment, variant calling ...
Clinical Variant Analyst information
What is a clinical variant analyst?
A Clinical Variant Analyst is a professional who interprets and analyzes genetic variants identified through clinical genetic testing. Their main role is to evaluate DNA sequence changes to determine their significance in relation to health and disease. They collaborate with geneticists, laboratory scientists, and clinicians to classify variants according to established guidelines and help inform patient diagnoses and management. Additionally, Clinical Variant Analysts review scientific literature, use databases, and may contribute to research and quality improvement in genetic testing.
What are some common challenges clinical variant analysts face when interpreting genetic data, and how can they be addressed?
Clinical Variant Analysts often encounter challenges such as distinguishing between benign and pathogenic variants, managing large datasets, and keeping up with rapidly evolving scientific literature. Addressing these challenges requires strong analytical skills, familiarity with bioinformatics tools, and ongoing collaboration with genetic counselors, laboratory directors, and clinicians. Staying current through continuous education and attending case discussions or multidisciplinary meetings also helps analysts provide accurate and clinically relevant interpretations.
What are the key skills and qualifications needed to thrive as a clinical variant analyst, and why are they important?
To thrive as a Clinical Variant Analyst, you need a strong background in genetics, molecular biology, and bioinformatics, typically supported by a relevant degree such as in genetics or molecular biology. Familiarity with next-generation sequencing (NGS) platforms, variant interpretation databases (like ClinVar), and clinical reporting software is commonly required, along with certifications such as ACMG variant interpretation training. Attention to detail, analytical thinking, and effective communication are vital soft skills for accurately interpreting genetic data and collaborating with clinical teams. These skills ensure accurate variant classification and reporting, directly impacting patient diagnosis and care.
What are popular job titles related to Clinical Variant Analyst jobs in Arizona?
For Clinical Variant Analyst jobs in Arizona, the most frequently searched job titles are:
What job categories do people searching Clinical Variant Analyst jobs in Arizona look for?
The top searched job categories for Clinical Variant Analyst jobs in Arizona are:
What cities in Arizona are hiring for Clinical Variant Analyst jobs?
Cities in Arizona with the most Clinical Variant Analyst job openings:
Full-time
Re-posted 25 days ago
Job description
Position Details
Department: PCH-MAIN | Lab Genomics
Location: Phoenix
Shift: Mon-Fri, Shifts Vary, 8am-5pm
Category: Laboratory/Pathology
Posting #: 1027389
Employee Type: Full-Time
Position Summary
The Clinical Genomics Scientist plays a critical role in variant interpretation, classification, and reporting to support clinical genomic testing. This position provides high-level scientific expertise in the analysis of genetic testing data including next-generation sequencing (NGS) such including NGS panels, whole exome sequencing (WES), and whole genome sequencing (WGS). The Clinical Genomics Scientist will work closely with Clinical Genomics physician leadership to ensure high-quality, clinically reliable genomic results and to advance the adoption of cutting-edge innovations in genomic testing. Responsibilities include supporting the director's efforts in test development, implementation, optimization, and validation, as well as contributing to the growth and development of Phoenix Children's Clinical Genomics Laboratory. This is a laboratory staff position with accountability to laboratory leadership for operational and administrative matters and to physician leadership for all clinical, scientific, and laboratory interpretation activities. The Clinical Genomics Scientist is expected to work within the priorities, direction, and defined scope established by laboratory leadership. Activities or commitments outside the defined scope of this role require advanced approval from laboratory leadership.
Position Duties
Phoenix Children's Mission, Vision, & Values
Mission
To advance hope, healing and the best healthcare for children and their families
Vision
Phoenix Children's will be the leading pediatric health system in the Southwest, nationally recognized for exceptional care, innovative research and advanced medical education.
We realize this vision by:
Department: PCH-MAIN | Lab Genomics
Location: Phoenix
Shift: Mon-Fri, Shifts Vary, 8am-5pm
Category: Laboratory/Pathology
Posting #: 1027389
Employee Type: Full-Time
Position Summary
The Clinical Genomics Scientist plays a critical role in variant interpretation, classification, and reporting to support clinical genomic testing. This position provides high-level scientific expertise in the analysis of genetic testing data including next-generation sequencing (NGS) such including NGS panels, whole exome sequencing (WES), and whole genome sequencing (WGS). The Clinical Genomics Scientist will work closely with Clinical Genomics physician leadership to ensure high-quality, clinically reliable genomic results and to advance the adoption of cutting-edge innovations in genomic testing. Responsibilities include supporting the director's efforts in test development, implementation, optimization, and validation, as well as contributing to the growth and development of Phoenix Children's Clinical Genomics Laboratory. This is a laboratory staff position with accountability to laboratory leadership for operational and administrative matters and to physician leadership for all clinical, scientific, and laboratory interpretation activities. The Clinical Genomics Scientist is expected to work within the priorities, direction, and defined scope established by laboratory leadership. Activities or commitments outside the defined scope of this role require advanced approval from laboratory leadership.
Position Duties
- Variant Interpretation and Reporting
Interpret and classify genetic variants for all assays including NGS assays (WES, WGS, targeted panels); apply ACMG/AMP guidelines and prepare evidence-based summaries. - Data Review and Quality Control
Review sequencing data to identify artifacts and ensure high-confidence variant calls; maintain documentation and compliance. - Validation and Implementation of New Technologies
Support validation and launch of new NGS and bioinformatics platforms, assuring accuracy and efficiency. - Clinical Reporting Collaboration
Collaborate with laboratory medical director(s), genetic counselor(s) to prepare and finalize clinical reports for patient care. - Workflow Development and Optimization
Work with bioinformatics and technical teams to troubleshoot pipelines and optimize variant analysis performance. - Gene and Variant Curation
Contribute to curation initiatives and update panel content to enhance clinical relevance and data consistency. - Quality Assurance and Compliance
Participate in internal audits, proficiency testing, and ongoing QC processes to uphold CLIA/CAP standards. - Training and Mentorship
Train and mentor technologists, fellows, and bioinformaticians in variant interpretation and workflow best practices. - Scientific Engagement
Stay current on emerging genomic technologies and present findings at internal meetings or conferences. - Performs miscellaneous job related duties as requested.
Phoenix Children's Mission, Vision, & Values
Mission
To advance hope, healing and the best healthcare for children and their families
Vision
Phoenix Children's will be the leading pediatric health system in the Southwest, nationally recognized for exceptional care, innovative research and advanced medical education.
We realize this vision by:
- Offering the most comprehensive care across ages, communities and specialties
- Investing in innovative research, including emerging treatments, tools and technologies
- Advancing education and training to shape the next generation of clinical leaders
- Advocating for the health and well-being of children and families
- We place children and families at the center of all we do
- We deliver exceptional care, every day and in every way
- We collaborate with colleagues, partners and communities to amplify our impact
- We set the standards of pediatric healthcare today, and innovate for the future
- We are accountable for making the highest quality care accessible and affordable
About Phoenix Children's Hospital
Sourced by ZipRecruiter
Phoenix Children's Hospital, located in Phoenix, AZ, is a prominent establishment within the healthcare industry. Known for its commitment to pediatric healthcare, the hospital provides a vast range of services catering to the unique health needs of children. Originally founded in 1983, Phoenix Children's Hospital prides itself on being one of the largest and most respected children's hospitals in the country. Guided by its mission–"to provide hope, healing and the best healthcare for children and their families"–the hospital holds strong on its core values of family-centered care, excellence in clinical care, innovation, and stewardship.
Industry
Health care and social assistance
Company size
1,001 - 5,000 Employees
Headquarters location
Phoenix, AZ, US
Year founded
1983