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Clinical Variant Analyst Jobs (NOW HIRING)

Cook Children's

Bioinformatician

Fort Worth, TX

... analytical pipelines for genomic data, performing variant annotation and interpretation, building tools for clinical decision support, and advancing data integration across genomics, clinical ...

Natera

OR

$126K - $166K/yr

The Clinical Genomics Engineering organization builds software that supports complex, regulated workflows spanning tertiary analysis workflows including variant interpretation, clinical review, and ...

Natera

Senior Product Manager, Clinical Genomics

$129K - $170K/yr

The Clinical Genomics Engineering organization builds software that supports complex, regulated workflows spanning tertiary analysis workflows including variant interpretation, clinical review, and ...

Natera

Senior Product Manager, Clinical Genomics

Austin, TX · On-site

$125K - $165K/yr

The Clinical Genomics Engineering organization builds software that supports complex, regulated workflows spanning tertiary analysis workflows including variant interpretation, clinical review, and ...

Guidehouse

Bioinformatics Support Analyst

$85K - $141K/yr

TWO (2) years experience working with bioscientific, genomic, or clinical data in a research or ... Knowledge of genomic data formats and tools (e.g., CRAM, variant calling pipelines) * Experience ...

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Clinical Variant Analyst information

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How much do clinical variant analyst jobs pay per hour?

As of Jul 9, 2026, the average hourly pay for clinical variant analyst in the United States is $39.80, according to ZipRecruiter salary data. Most workers in this role earn between $31.49 and $45.67 per hour, depending on experience, location, and employer.

What is the highest paying job in genetics?

In genetics, roles such as genetic counselors, clinical geneticists, and research directors tend to have the highest salaries. Senior positions requiring advanced degrees, certifications, and extensive experience typically offer the highest compensation in the field.

What is a Clinical Variant Analyst?

A Clinical Variant Analyst is a professional who interprets and analyzes genetic variants identified through clinical genetic testing. Their main role is to evaluate DNA sequence changes to determine their significance in relation to health and disease. They collaborate with geneticists, laboratory scientists, and clinicians to classify variants according to established guidelines and help inform patient diagnoses and management. Additionally, Clinical Variant Analysts review scientific literature, use databases, and may contribute to research and quality improvement in genetic testing.

What are some common challenges Clinical Variant Analysts face when interpreting genetic data, and how can they be addressed?

Clinical Variant Analysts often encounter challenges such as distinguishing between benign and pathogenic variants, managing large datasets, and keeping up with rapidly evolving scientific literature. Addressing these challenges requires strong analytical skills, familiarity with bioinformatics tools, and ongoing collaboration with genetic counselors, laboratory directors, and clinicians. Staying current through continuous education and attending case discussions or multidisciplinary meetings also helps analysts provide accurate and clinically relevant interpretations.

What are the key skills and qualifications needed to thrive as a Clinical Variant Analyst, and why are they important?

To thrive as a Clinical Variant Analyst, you need a strong background in genetics, molecular biology, and bioinformatics, typically supported by a relevant degree such as in genetics or molecular biology. Familiarity with next-generation sequencing (NGS) platforms, variant interpretation databases (like ClinVar), and clinical reporting software is commonly required, along with certifications such as ACMG variant interpretation training. Attention to detail, analytical thinking, and effective communication are vital soft skills for accurately interpreting genetic data and collaborating with clinical teams. These skills ensure accurate variant classification and reporting, directly impacting patient diagnosis and care.

What is the highest paying analyst job?

Among analyst roles, senior or specialized positions such as data science managers, financial directors, or clinical research directors tend to have the highest salaries. Clinical Variant Analysts with advanced certifications and experience in genomic data analysis can also command higher compensation, especially in biotech or pharmaceutical industries.

What does a variant analyst do?

A clinical variant analyst examines genetic data to identify and interpret variations in DNA sequences that may be linked to diseases. They analyze sequencing results using bioinformatics tools, review scientific literature, and collaborate with healthcare professionals to determine the clinical significance of genetic variants. This role often requires knowledge of genetics, molecular biology, and proficiency with data analysis software.

What biology jobs pay over $100k?

Clinical Variant Analysts and other specialized genetics professionals can earn over $100,000 annually, especially with advanced degrees, certifications, and experience in genomic analysis, bioinformatics, or laboratory management. High-paying roles often require proficiency with tools like next-generation sequencing and knowledge of genetic databases, typically found in research institutions or biotech companies.
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Clinical Variant Analyst jobs near you
Infographic showing various Clinical Variant Analyst job openings in the United States as of July 2026, with employment types broken down into 1% Locum Tenens, 1% Internship, 86% Full Time, 6% Part Time, 1% Temporary, and 5% Contract. Highlights an 82% Physical, 5% Hybrid, and 13% Remote job distribution, with an average salary of $82,791 per year, or $39.8 per hour.
Bioinformatician

Bioinformatician

Cook Children's

Fort Worth, TX

Full-time

Re-posted 28 days ago

Cook Children's Health Care System rating

7.7

Company rating: 7.7 out of 10

Based on 74 frontline employees who took The Breakroom Quiz

159th of 880 rated healthcare providers

Job description

Location:

Medical Center Office Building (901 7th Ave)

Department:

Pediatric Precision Health Program

Shift:

First Shift (United States of America)

Standard Weekly Hours:

40

Summary:

The Bioinformatician will support the Cook Children's precision health and precision medicine research ecosystem by developing and maintaining analytical pipelines for genomic data, performing variant annotation and interpretation, building tools for clinical decision support, and advancing data integration across genomics, clinical phenotypes, and functional datasets. This role supports precision clinics, genome-informed care, research, and AI-enabled clinical workflows. This position will collaborate closely with Cook Children's variant scientists, genetic counselors, clinicians, data scientists, and computational teams.

Experience

  • 2 years experience in genomic data processing, variant annotation, or large-scale data analysis

  • Demonstrated proficiency in R and/or Python, SQL, Linux/Unix environments, and common bioinformatics workflows

Education

  • Master's degree in Bioinformatics, Computational Biology, Genetics, Data Science, Computer Science, or related field

About Us:

Cook Children's Health Care System

Cook Children's Health Care System offers a unique approach to caring for children because we are one of the country's leading integrated pediatric health care delivery organizations. Patients benefit from the integrated system because it allows Cook Children's to use all of its resources to treat a patient and allows for easy communication between the various companies by physicians with a focus on caring for children and adolescents.

Cook Children's is an equal opportunity employer. As such, Cook Children's offers equal employment opportunities without regard to race, color, religion, sex, age, national origin, physical or mental disability, pregnancy, protected veteran status, genetic information, or any other protected class in accordance with applicable federal laws. These opportunities include terms, conditions and privileges of employment, including but not limited to hiring, job placement, training, compensation, discipline, advancement and termination.

What Cook Children's Health Care System employees say

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Benefits

Hours and flexibility

Workplace

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Cook Children's Health Care System logo

About Cook Children's Health Care System

Sourced by ZipRecruiter

Cook Children's Health Care System, based in Fort Worth, Texas, operates in the healthcare industry with a primary focus on pediatric health services. Established in 1918, the system has been committed to improving the health of children through the prevention and treatment of childhood diseases. This integrated pediatric healthcare system includes a medical center, physician network, home health company, research institute, and a health plan. At the core of its operations is the mission to 'Improve the Health of Every Child' in its community, reflecting its commitment to providing quality care, research, education, and prevention and wellness services.

Industry

Health care and social assistance

Company size

5,001 - 10,000 Employees

Headquarters location

Fort Worth, TX, US

Year founded

1918

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