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Scisco Genetics

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Bioinformatics Scientist / Genomic Data Analyst

Seattle, WA · On-site

$95K - $115K/yr

Analyze high-throughput genomic sequence data, including whole-genome sequencing, whole-exome ... control, variant calling, annotation, and downstream interpretation. * Investigate genetic ...

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How much do variant analyst jobs pay per year?

As of Jun 22, 2026, the average yearly pay for variant analyst in the United States is $73,261.00, according to ZipRecruiter salary data. Most workers in this role earn between $52,500.00 and $87,000.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive in the Variant Analyst position, and why are they important?

To thrive as a Variant Analyst, you need a solid background in genetics or molecular biology, experience in data analysis, and a relevant bachelor's or advanced degree. Familiarity with bioinformatics tools such as Variant Call Format (VCF) analysis software, genomic databases, and proficiency in scripting languages like Python or R is highly valued, as is certification in clinical genetics or genomics. Strong attention to detail, analytical thinking, and effective communication skills distinguish top candidates in this field. These skills and qualities ensure accurate variant interpretation, effective cross-functional collaboration, and meaningful contributions to diagnostics or research.

What are the typical daily responsibilities of a Variant Analyst?

A Variant Analyst typically spends their day analyzing genetic sequencing data to identify, classify, and interpret genetic variants of clinical or research significance. They utilize specialized bioinformatics software to process raw data, review scientific literature for evidence supporting variant classification, and document their findings in detailed reports. Collaboration is common, as analysts often work closely with laboratory geneticists, clinicians, and other members of a multidisciplinary team to ensure accurate and relevant results. Staying updated with the latest guidelines and advances in genomics is also an important part of the role.

What is a Variant Analyst job?

A Variant Analyst is a professional who analyzes genetic variations in DNA sequences to identify mutations associated with diseases or traits. They interpret sequencing data, use bioinformatics tools, and contribute to clinical or research-based genetic analyses. Their work helps in diagnosing genetic disorders, guiding treatment decisions, and advancing precision medicine.

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What cities are hiring for Variant Analyst jobs? Cities with the most Variant Analyst job openings:
What are the most commonly searched types of Variant Analyst jobs? The most popular types of Variant Analyst jobs are:
What states have the most Variant Analyst jobs? States with the most job openings for Variant Analyst jobs include:
What job categories do people searching Variant Analyst jobs look for? The top searched job categories for Variant Analyst jobs are:
Variant Analyst jobs near you
Infographic showing various Variant Analyst job openings in the United States as of June 2026, with employment types broken down into 55% Locum Tenens, 7% As Needed, 35% Full Time, 1% Part Time, 1% Nights, and 1% Summer. Highlights an 81% Physical, 8% Hybrid, and 11% Remote job distribution, with an average salary of $73,261 per year, or $35.2 per hour.
Bioinformatics Scientist / Genomic Data Analyst

Bioinformatics Scientist / Genomic Data Analyst

Scisco Genetics

Seattle, WA • On-site

$95K - $115K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 21 days ago

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Job description

We are seeking a highly trained Bioinformatics Scientist with a PhD or equivalent research experience in bioinformatics, computational biology, genetics, genomics, immunology, or a closely related field. The ideal candidate will have strong experience analyzing genomic sequence data and a deep interest in the genetic basis of human immune response.

This role will focus on the analysis and interpretation of genomic, transcriptomic, and/or immune-related sequence datasets to help identify genetic variation, molecular pathways, and biological mechanisms associated with human immune function, immune response, disease susceptibility, vaccine response, inflammation, autoimmunity, infection, or related phenotypes.


Key Responsibilities

The selected candidate will:

  • Analyze high-throughput genomic sequence data, including whole-genome sequencing, whole-exome sequencing, targeted sequencing, and related datasets.
  • Develop, implement, and optimize bioinformatics pipelines for sequence data processing, quality control, variant calling, annotation, and downstream interpretation.
  • Investigate genetic contributors to human immune response, including HLA variation, immune receptor loci, cytokine pathways, host-pathogen response, or other immunogenetic features.
  • Integrate genomic data with clinical, phenotypic, immunological, or functional datasets.
  • Interpret results in a biologically meaningful context and communicate findings to interdisciplinary teams.
  • Prepare reports, figures, manuscripts, grant materials, or presentations summarizing analytical methods and scientific findings.
  • Collaborate with scientists, clinicians, computational biologists, immunologists, and other stakeholders.


Required Qualifications

  • PhD in bioinformatics, computational biology, human genetics, genomics, immunology, biostatistics, or a related discipline.
  • Demonstrated experience analyzing genomic sequence data.
  • Strong understanding of human genetics and genomic variation.
  • Familiarity with immune response genetics, immunogenomics, host-pathogen genetics, vaccine response genetics, autoimmunity, inflammatory disease, or related areas.
  • Proficiency in programming and data analysis using tools such as Python, R, Bash, Nextflow, Snakemake, or similar platforms.
  • Experience working in Linux/Unix computing environments and with high-performance computing or cloud-based analysis systems.
  • Familiarity with standard bioinformatics tools and file formats, such as FASTQ, BAM/CRAM, VCF, GTF/GFF, BED, BCFtools, GATK, PLINK, STAR, HISAT2, Salmon, Seurat, or related tools.
  • Ability to work independently, manage complex datasets, and document analytical workflows clearly.


Preferred Qualifications

  • Experience with HLA typing, immune repertoire sequencing, single-cell immune profiling, GWAS, eQTL analysis, or rare variant analysis.
  • Familiarity with population structure, ancestry inference, polygenic risk scores, or fine-mapping methods.
  • Prior publications or demonstrated research contributions in immunogenetics, infectious disease genetics, autoimmune disease genetics, cancer immunology, vaccine response, or related fields.
  • Experience with reproducible workflow development, containerization, Git-based version control, or cloud platforms such as AWS, Google Cloud, or Azure.


Desired Skills and Attributes

  • Strong analytical and problem-solving skills.
  • Excellent scientific communication skills.
  • Ability to collaborate across computational, biological, and clinical teams.
  • Careful attention to data quality, reproducibility, and documentation.
  • Intellectual curiosity and interest in the genetic determinants of human immune function.



Company Description

Scisco Genetics, a Seattle-based biotechnology company, specializes in next-generation sequencing (NGS) services and products for genotyping complex immune gene systems, including HLA, KIR, MICAB, FCGR, and IGHG. Founded and led by Dr. Daniel Geraghty, whose research at the Fred Hutchinson Cancer Research Center focuses on immune genetics, the company offers tools like the ScisGo product and Version 6 NGS HLA Typing Kit for high-resolution, accurate genotyping, supporting applications such as hematopoietic cell transplants and precision medicine.