Senior Software Engineer Jobs in Rochester, MN (NOW HIRING)

The Mayo Clinic IT Radiology AI unit is seeking a talented and motivated professional to contribute to the advancement of Radiology Artificial Intelligence initiatives. As part of the Framework for AI Software Technologies (FAST) program, you will join scientists, engineers, and clinicians to turn prototypes-including generative-AI and large-language-model solutions-into secure, cloud-native applications that enhance patient care.
In this collaborative role, you will analyze requirements, develop robust software applications, validate integrations with clinical systems, and provide operational support for production workflows. Success is built on experience with Python coding, modern cloud platforms, machine learning, and medical imaging. Familiarity with Generative AI, LLMs, FHIR, Google Cloud, and Epic integrations is especially valuable.
Responsibilities:
• Participate in DevOps, Agile, continuous development and integration frameworks.
• Programming in high-level languages such as Python, Go, C, C++, C#, Java, etc.
• Work on deployment automation/configuration management with tools including but not limited to ADO, GitHub, Azure Pipelines, Terraform following a DevOps model.
• Ensure all appropriate documentation of processes and source code is created and maintained.
• Communicate effectively with peers, leaders, and customers throughout the organization.
• Participate in expert level troubleshooting and resolve problems through root cause analysis, data, and system investigation.
• Continue to build knowledge of the organization, processes, and customers.
• Use prescribed guidelines or policies to analyze and resolve problems.
• Receive a moderate level of guidance and direction.
• Participate with the team in providing 24/7 call support.
Qualifications
Bachelor's degree in Computer Science/Engineering or related field; Or an Associates' degree in Computer Science/Engineering or related field with an additional 2 years of experience as described below.
• Working knowledge and experience of Software Engineering with a minimum of internships and a minimum of 1 yr. of experience, or 2 yrs of experience coding applications or services in a high-level language (Python, C, C++, Go, Java, C# etc.).
• Familiarity with modern tools for generative AI, including large language models, prompt engineering, and retrieval augmented generation.
• Demonstrated problem solving and time management skills.
• Strong technical aptitude for designing and implementing software solutions.
• Experience with modern application development frameworks.
• Knowledge of professional software-engineering practices across the full development life cycle-coding standards, code reviews, source-control management, build processes, testing, and operations.
• Deep hands-on technical expertise coupled with excellent verbal and written communications.
• Experience with Agile software development methods.
Preferred Technology Experience:
• Ability to use a wide variety of open-source technologies and cloud-based services.
• Experience with cloud environments (Google, AWS, Azure).
• Experience with Python programming language.
• Experience in databases, analytics, big data systems or business intelligence products.
• Experience building high-performance, highly available and scalable distributed systems.
• Experience developing software for healthcare related industries.
This vacancy is not eligible for sponsorship/we will not sponsor or transfer visas for this position. Mayo Clinic DOES NOT participate in the F-1 STEM OPT extension program.
About Us
Why Mayo Clinic
Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans - to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.
Benefits Highlights

• Medical: Multiple plan options.
• Dental: Delta Dental or reimbursement account for flexible coverage.
• Vision: Affordable plan with national network.
• Pre-Tax Savings: HSA and FSAs for eligible expenses.
• Retirement: Competitive retirement package to secure your future.

About the Team
Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is.
Equal Opportunity
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law". Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.