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Senior Python Software Engineer Jobs in Colorado

Senior Software Engineer

CO · On-site

$121K - $159K/yr

Senior Software Engineer REPORTS TO: Sr. Director of Engineering -- Data Platform DIRECT REPORTS: N ... Strong work in at least one of TypeScript, Python, Go, or Rust, and willingness to pick up the ...

#Senior Software Engineer

Boulder, CO · On-site

$128K - $170K/yr

... development in Python. • Knowledge of RTOS, SoC architecture (core, cache, memory, bus ... of Software Engineering or related work experience. • OR Master's degree in Engineering ...

Software Engineer Onsite Location: Aurora, CO Required: TS/SCI Clearance No 1099, No third parties ... For a more senior level: * Experience developing software using C++ and Python. Responsibilities:

Senior Software Engineer Description - Fusion/ODF is a Windows-based low-level device platform ... Python (Programming Language) React.js Scalability Software Development Software Engineering SQL ...

Software Engineer, Senior

Aurora, CO · On-site

$100.18 - $120.20/hr

Job Title Software Engineer, Senior Overview EverWatch is a government solutions company providing ... Experience with Python 3.12, asyncio and pydantic libraries * Experience with DevOps practices and ...

Senior Software Engineer

Colorado Springs, CO · On-site +1

$120K - $160K/yr

SW Engineer Schedule: Full-Time Shift: Day Job Travel: Yes - 10% of the time Minimum Clearance ... Experience developing software with C/C++, Java, Python and FORTRAN. * Experience in Agile ...

Senior Software Engineer

Aurora, CO · On-site

$170K - $260K/yr

Are you a Senior Software Engineer who is ready for a new challenge that will launch your career to ... Python development * AWS ML certificate or Knowledge implementing production scale AI/ML solutions ...

Sr Software Engineer

Boulder, CO · On-site

$106K - $145K/yr

We are seeking a Senior Software Engineer to join the team building the control system software for ... Experience with Python and at least one compiled language, with a desire to learn and work in Rust

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Senior Python Software Engineer information

See Colorado salary details

$57.8K

$149.3K

$205K

How much do senior python software engineer jobs pay per year?

As of Jun 27, 2026, the average yearly pay for senior python software engineer in Colorado is $149,290.00, according to ZipRecruiter salary data. Most workers in this role earn between $127,800.00 and $171,900.00 per year, depending on experience, location, and employer.

What is the difference between Senior Python Software Engineer vs Python Developer?

AspectSenior Python Software EngineerPython Developer
Required CredentialsBachelor's degree in CS or related field, experience in software engineeringBachelor's degree in CS or related field, coding proficiency
Work EnvironmentDesigning complex systems, leading projects, mentoringWriting code, developing applications, debugging
Employer & Industry UsageTech companies, startups, enterprise softwareWeb development, data analysis, automation projects
Common Search & Comparison IntentUnderstanding senior-level roles, responsibilities, and skillsEntry to mid-level coding roles, project involvement

The main difference between a Senior Python Software Engineer and a Python Developer lies in experience, responsibilities, and scope. Senior engineers typically lead projects, design system architecture, and mentor junior staff, while Python Developers focus on coding, application development, and implementation. Both roles require strong Python skills and relevant credentials, but senior roles demand more experience and leadership capabilities.

What are some common challenges faced by Senior Python Software Engineers when leading complex projects, and how can they be addressed?

Senior Python Software Engineers often face challenges such as balancing hands-on coding with mentoring junior team members, managing technical debt, and designing scalable solutions. Successfully addressing these challenges involves clear communication, proactive code reviews, and effective prioritization of tasks. Collaborating closely with cross-functional teams and fostering a culture of knowledge sharing can also help ensure project success and team growth.

What is the salary of senior Python developer?

The salary of a senior Python software engineer typically ranges from $100,000 to $150,000 annually, depending on experience, location, and industry. Skilled professionals with expertise in frameworks like Django or Flask and experience with cloud services may earn higher compensation.

Will AI replace Python coders?

AI tools can automate certain coding tasks, but Senior Python Software Engineers are essential for designing, developing, and maintaining complex software systems. AI is more likely to augment coding work rather than fully replace experienced developers, who bring problem-solving, creativity, and domain expertise that AI cannot replicate fully.

What are the key skills and qualifications needed to thrive as a Senior Python Software Engineer, and why are they important?

To thrive as a Senior Python Software Engineer, you need advanced proficiency in Python programming, strong problem-solving abilities, and a solid background in computer science or a related field. Familiarity with frameworks like Django or Flask, experience with version control systems such as Git, and knowledge of cloud platforms and CI/CD tools are typically required. Leadership, effective communication, and mentorship skills help you collaborate with teams and guide junior developers. These skills ensure the delivery of robust, scalable software solutions and foster a productive, innovative development environment.

What engineers make $500,000?

Senior Python Software Engineers with extensive experience, specialized skills in areas like machine learning or data engineering, and working in high-paying industries such as finance or tech can earn $500,000 or more annually. Compensation often includes base salary, bonuses, and stock options, especially at large tech companies or startups with significant funding.

What does a Senior Python Software Engineer do?

A Senior Python Software Engineer designs, develops, tests, and maintains complex software applications using the Python programming language. They often lead or mentor junior developers, architect software solutions, and ensure best coding practices are followed. These professionals collaborate with cross-functional teams to deliver scalable and efficient systems, troubleshoot issues, and optimize application performance. Their expertise includes advanced knowledge of Python frameworks, libraries, and development tools, as well as experience with databases, APIs, and cloud services.

Is it possible to make 300k as a software engineer?

Senior Python software engineers with extensive experience, specialized skills, and working in high-paying industries or companies can reach or exceed a $300,000 annual salary, especially with bonuses and stock options. Achieving this level often requires advanced knowledge of frameworks, cloud platforms, and a strong track record of project success.
What cities in Colorado are hiring for Senior Python Software Engineer jobs? Cities in Colorado with the most Senior Python Software Engineer job openings:
Senior Software Engineer I/II - Simulation Engineering

Senior Software Engineer I/II - Simulation Engineering

Rocket Lab Corporation

Littleton, CO

$122K - $161K/yr

Other

Posted 9 days ago


Rocket Lab rating

8.8

Company rating: 8.8 out of 10

Based on 6 frontline employees who took The Breakroom Quiz

9th of 60 rated aerospace companies


Job description

SPACE SYSTEMS

At Rocket Lab, we're not just launching rockets - we're building the future of space. Our Space Systems team builds everything from complete spacecraft, precision payloads to the components and subsystems that allow them to thrive in space, like solar panels, flight software, star trackers, optical systems, separation systems, radios, and more.

Our Space Systems team has enabled more than 1,700 missions, ranging from interplanetary exploration, in-space manufacturing to national security and defense initiatives. The team has built spacecraft, payloads, and components for missions to the Moon and Mars, working with partners including NASA, the Space Development Agency, and the U.S. Space Force. Whether it's a single high-performance spacecraft, constellation, or the vertically integrated components that help them get to space - our world class Space Systems team is empowering some of the boldest and most ambitious space missions. 

SENIOR SOFTWARE ENGINEER I/II - SIMULATION ENGINEERING

We are seeking a highly skilled and experienced Senior Software Engineer I/II - Simulation Engineering to join our team, based out of our Littleton, CO site. In this role, you will focus on architecting large-scale simulation environments and driving high-level data analysis to solve complex aerospace challenges. You will work closely with cross-functional teams to design distributed simulation campaigns, extract actionable insights from massive datasets, and support critical mission decision-making processes. This position is ideal for someone with a strong background in big data analysis, distributed computational modeling, and software systems architecture, who thrives in solving constellation-level technical problems.

WHAT YOU'LL GET TO DO:

  • Architect and deploy large-scale, distributed simulation environments for complex aerospace systems, including multi-vehicle and constellation-level modeling.
  • Develop robust data pipelines to process, analyze, and visualize massive datasets generated by high-fidelity simulations.
  • Derive actionable engineering and mission-level insights through advanced statistical analysis and data modeling of simulation outputs.
  • Optimize simulation infrastructure for high-performance computing (HPC) and distributed cluster environments to ensure scalability.
  • Collaborate with domain experts to define campaign-level requirements and translate mission objectives into scalable simulation architectures.
  • Lead the integration of complex simulation ecosystems, ensuring synchronization across multiple subsystems and analytical tools. 

(Please note: This position can be hired at the Senior Software Engineer I or Senior Software Engineer II level.) 

QUALIFICATIONS YOU'LL BRING AS SENIOR SOFTWARE ENGINEER I:

  • Bachelor's degree in Computer Science, Engineering, Applied Mathematics, Physics, or a related field.
  • 5+ years of industry experience focusing on large-scale simulation engineering, data analysis, or distributed computational modeling. 
  • Proficiency in languages used for heavy data analysis and simulation infrastructure (e.g., Python, C++, or similar). 
  • Demonstrated experience architecting and analyzing large-scale Monte Carlo campaigns. 
  • Experience processing and analyzing large datasets using modern data analytics libraries or frameworks. 
  • Experience modeling complex, multi-component physical systems (e.g., spacecraft constellations, multi-vehicle architectures, or robotics). 
  • U.S citizenship required, due to program requirements. 

QUALIFICATIONS YOU'LL BRING AS SENIOR SOFTWARE ENGINEER I:

  • Bachelor's degree in Computer Science, Engineering, Applied Mathematics, Physics, or a related field.
  • 5+ years of industry experience focusing on large-scale simulation engineering, data analysis, or distributed computational modeling. 
  • Proficiency in languages used for heavy data analysis and simulation infrastructure (e.g., Python, C++, or similar). 
  • Demonstrated experience architecting and analyzing large-scale Monte Carlo campaigns. 
  • Experience processing and analyzing large datasets using modern data analytics libraries or frameworks. 
  • Experience modeling complex, multi-component physical systems (e.g., spacecraft constellations, multi-vehicle architectures, or robotics). 
  • U.S citizenship required, due to program requirements. 

THESE QUALIFICATIONS WOULD BE NICE TO HAVE:

  • Active Secret clearance, Top Secret clearance, or ability to obtain and maintain one
  • Strong familiarity with high-performance computing (HPC), parallel processing, and distributed compute clusters (e.g., Docker Swarm, Kubernetes). 
  • Experience in multi-vehicle or synchronized distributed simulation environments. 
  • Advanced understanding of statistical analysis, data visualization techniques, and optimization algorithms. 
  • Experience with machine learning or AI-driven methodologies applied to large dataset analysis or simulation generation. 
  • Familiarity with cloud-based simulation platforms or large-scale data lakes. 
  • Proven ability to tackle complex architectural challenges and deliver innovative data solutions. 

This position may require prolonged periods of sitting, standing, walking, computer work, and occasional exposure to moderate levels of noise, dust, and fumes in production areas.