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Senior Portfolio Manager Jobs in Indiana (NOW HIRING)

Manage a commercial loan portfolio of clients * Make loan presentations and recommendations to Credit, team leaders, and senior line of business managers as required * Partner with credit and ...

Manage a commercial loan portfolio of clients * Make loan presentations and recommendations to Credit, team leaders, and senior line of business managers as required * Partner with credit and ...

... senior leadership with clear visibility into delivery, risks, and outcomes. Primary responsibilities: PMO Leadership & Governance * Define project intake, prioritization, and portfolio management ...

CRE Relationship Manager

Fishers, IN · On-site

$85 - $120/hr

Manage a commercial loan portfolio of clients * Make loan presentations and recommendations to credit, team leaders, and senior line-of-business managers as required * Partner with credit and ...

... senior leadership with clear visibility into delivery, risks, and outcomes. Primary responsibilities: PMO Leadership & Governance * Define project intake, prioritization, and portfolio management ...

... senior leadership with clear visibility into delivery, risks, and outcomes. Primary responsibilities: * Define project intake, prioritization, and portfolio management processes aligned to business ...

Showing results 41-60

Senior Portfolio Manager information

See Indiana salary details

$42.8K

$97.9K

$115.6K

How much do senior portfolio manager jobs pay per year?

As of Sep 6, 2026, the average yearly pay for senior portfolio manager in Indiana is $97,852.00, according to ZipRecruiter salary data. Most workers in this role earn between $79,000.00 and $110,900.00 per year, depending on experience, location, and employer.

What does a senior portfolio manager do?

A Senior Portfolio Manager is responsible for overseeing and managing investment portfolios on behalf of clients or institutions, with the goal of maximizing returns while managing risk. They develop investment strategies, analyze market trends, select appropriate securities, and continuously monitor portfolio performance. In addition, they often lead a team of analysts and junior managers, communicate with clients, and ensure portfolios align with clients’ financial goals and risk tolerance. Senior Portfolio Managers typically have extensive experience in finance, strong analytical skills, and a deep understanding of financial markets.

What are the key skills and qualifications needed to thrive as a senior portfolio manager?

To thrive as a Senior Portfolio Manager, you need advanced knowledge of investment strategies, financial analysis, and portfolio construction, typically supported by a relevant degree and credentials like the CFA designation. Expertise in portfolio management software, financial modeling tools, and risk assessment systems is commonly required. Strong leadership, communication, and decision-making skills help build client trust and effectively manage teams. These competencies are crucial for delivering consistent investment performance, managing risk, and maintaining client satisfaction in a competitive financial environment.

How does a senior portfolio manager typically collaborate with analysts and other investment professionals within a firm?

Senior Portfolio Managers often work closely with research analysts, junior portfolio managers, and trading teams to develop and execute investment strategies. They rely on analysts to provide in-depth market research and sector insights, which inform asset allocation and security selection decisions. Regular team meetings and strategy sessions are common to ensure alignment and to adapt to market changes. Effective collaboration helps maintain a well-balanced portfolio and enables the Senior Portfolio Manager to make informed, timely investment decisions that align with client objectives.

What is the difference between Senior Portfolio Manager vs Portfolio Analyst?

AspectSenior Portfolio ManagerPortfolio Analyst
Required CredentialsTypically requires CFA, MBA, or similar certificationsOften requires a bachelor's degree; CFA is a plus
Work EnvironmentLeads investment strategies, manages portfolios, makes high-level decisionsConducts research, analyzes data, supports portfolio decisions
Employer & Industry UsageUsed in asset management firms, hedge funds, institutional investorsCommon in investment firms, banks, financial advisory companies

The main difference between a Senior Portfolio Manager and a Portfolio Analyst lies in their responsibilities and experience level. Senior Portfolio Managers oversee investment strategies and make high-stakes decisions, while Portfolio Analysts support these decisions through research and analysis. Both roles are integral to investment management but differ in scope and seniority.

What are popular job titles related to Senior Portfolio Manager jobs in Indiana?

For Senior Portfolio Manager jobs in Indiana, the most frequently searched job titles are:

What job categories do people searching Senior Portfolio Manager jobs in Indiana look for?

The top searched job categories for Senior Portfolio Manager jobs in Indiana are:

What cities in Indiana are hiring for Senior Portfolio Manager jobs?

Cities in Indiana with the most Senior Portfolio Manager job openings:

Infographic showing various Senior Portfolio Manager job openings in Indiana as of August 2026, with employment types broken down into 100% Full Time. Highlights an 73% In-person, 9% Hybrid, and 18% Remote job distribution, with an average salary of $97,852 per year, or $47 per hour.

Senior Director, Project Management

Indiana Biosciences Research Institute Inc

Indianapolis, IN • On-site

Full-time

Medical, Life

Re-posted 18 days ago


Key responsibilities

  • Build and maintain the IBRI Project Management Office (PMO) including processes, tools, and technologies.

  • Manage the full lifecycle of the IBRI project portfolio, including project intake, delivery, and completion.

  • Lead and manage the IBRI project management and portfolio management systems, ensuring project progress, milestone achievement, and reporting to executive leadership.


Job description

IBRI is poised to transform life sciences-and for millions of people, even life itself.


The Opportunity:

The Director/Senior Director of Project Management serves as an important member of the Project/Grant Management/Governance team at the IBRI.  Their overarching responsibility is to build and maintain a comprehensive (processes, tools, technologies) Project Management Office (PMO) tailored to IBRI's Research and Innovation goals. Building on the strong foundation of project management strategies, processes and tools, they will work across all research areas to ensure project delivery excellence. They will partner with scientists, business development, philanthropy and across the IBRI scientific ecosystem to deliver a sustainable portfolio of research and translational projects to achieve the IBRI's mission. 

This role is responsible for full lifecycle management of the IBRI project portfolio, including project intake from all sources of scientific, government or business development, portfolio entry, project delivery and completion Proposals span a range of funding sources, including private companies, federal and state agencies, health organizations, and private foundations. 

This leadership role provides strategic guidance and hands-on support to deliver IBRI's project/portfolio aligned with scientific priorities and institutional goals. The VP/Senior Director ensures all projects follow the IBRI Project Management system, and that IBRI executive management is well informed about project and portfolio project. The position requires strong cross-functional collaboration to streamline processes, mitigate risk, and enhance funding success. These responsibilities require a combination of scientific knowledge, project management skills, and relationship management.


Responsibilities:

Project Management Leadership

Lead and manage the IBRI project management system

Ensure that IBRI projects progress according to plan and that key deliverables and milestones are achieved on schedule. This includes developing Target Data Packages, Target Product Profiles, tracking the project progress, identifying and addressing issues or delays, and adjusting plans, as necessary. 

Sustain and improve a comprehensive IBRI project management strategy, processes and tools to ensure optimal support for scientists, as well as to optimize outcomes the IBRI.

Coordinate between Institute management, scientists, and finance to ensure all elements of the budgets and workplans are developed, implemented and communicated appropriately. 

Collaborate with Finance, Project Management, Business Development, Philanthropy, and other internal and external stakeholders to inform key business planning activities.

Act as point of contact with CROs/consultants working on behalf of project teams, including monitoring of the CRO/consultant performance and addressing issues that arise, and ensuring that the quality of work meets the project's standards.

Portfolio Management

Lead and manage the IBRI portfolio management system.

Lead and manage the IBRI Project/Governance system, which includes regularly reporting progress to IBRI executive leadership.

In-depth understanding of the science and business behind the progression of all projects in the portfolio, 

Lead strategic alignment discussions regarding project progression to optimize the translational aspects of the IBRI portfolio.

Collaboratively ensure routine and comprehensive portfolio reporting to IBRI Executive Management.

Pre-project Portfolio Management

Lead the full project entry process, including identifying and clarifying project opportunities with internal and external collaborators, guiding proposal development, and ensuring timely governance Review.

Collaborate closely with scientific staff and principal investigators to align proposals with research objectives and funding requirements.

Partner with internal stakeholders (Finance, Project Management, leadership) to develop accurate plans and budgets and confirm resource availability.

Ensure all governance packages are complete and accurate to enable optimal decision-making.

Process Improvement

Identify and implement opportunities to continuously improve IBRI's project and governance management systems, tools and technologies.

Collaborate with all IBRI scientific and functional leaders to streamline workflows and enable best project management practices.

Teamwork & Collaboration

Ability to work in a team-based collaborative environment toward our strategic and organizational goals.

Collaborates cross-functionally to drive our innovation and inclusion in our discovery of positive patient outcomes.

Integrity

Adherence to facility and lab safety policies and standards, and take ownership of your wellbeing, as well as those you work with.

Commitment to ethical and honest principles to ensure we uphold the credibility of our findings and our organization.

Follow IBRI values, policies, procedures, and expectations, as well as any laws and/or rules pertaining to our work.


Qualifications:

M.S. or Ph.D. degree required.

Minimum 7 years project management experience, preferably in a pharmaceutical or biotech life sciences company

Strong leadership and networking skills.

Excellent organization, communication, and interpersonal skills.

Ability to develop and implement strategic plans for project and governance management.


Compensation:

Competitive salary and comprehensive benefits offered commensurate with experience


About Us:

The Indiana Biosciences Research Institute (IBRI) is a first-in-class translational medicine institute dedicated to advancing life sciences in the race to eliminate disease and improve human health and life.

By connecting early-stage biotech companies with cutting-edge life science discoveries -and backed by the mission and resources of industry leaders, investors, and philanthropic partners-IBRI is successfully evolving a new, independent model to conquer disease, uniting previously fragmented forces in the quest for cures.

Carefully curating and supporting early-stage companies with investment, talent, and space, IBRI strategically accelerates drug discovery. Our work benefits from the relatively low cost of living and doing business here, allowing more resources to be directed toward science.

Fueled by the same entrepreneurial creativity as the groundbreaking scientific work we support, IBRI's labs advance research across the frontiers of diabetes, metabolic disease, Alzheimer's disease, and rare pediatric diseases. Our ambitious public-private vision cultivates talent while efficiently bridging the gap between research-driven inquiry and profit-driven drug development.

At IBRI, cures are launched on a clear pathway to clinical trials, enabled by the combined resources and experience of our academic and industry partners, without the typical pressure to deliver rapid results for commercialization. IBRI labs pursue breakthroughs that might never happen elsewhere. Breakthroughs are happening here. Our novel financing model ensures that when discoveries are ready for clinical trials, the intellectual property is sold back to industry or spun off, creating a direct stream of revenue.

By every measure, the IBRI model demonstrates a novel approach that delivers rewards. Scientific bench work is nurtured, drug discovery is advanced, workforce development is continuous, investors see returns, and donors see impact. Most importantly, IBRI's structure and portfolio of accomplishments matter to the patients whose lives are improved-or even saved-by this forward-looking approach to life sciences.

IBRI is driven to bring next-generation therapies to market with an understanding of the complex pressures that often bind innovation to economics. After more than a decade, the evidence is clear: IBRI is poised to transform life sciences-and for millions of people, even life itself.

Equal Employment Opportunity:

The IBRI provides equal employment opportunities to all employees and applicants and does not discriminate based on age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability, or any other legally protected status.