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Senior Manufacturing Process Engineer Jobs in Raleigh, NC

Salas O'Brien, Inc.

Process Engineer

Raleigh, NC

Support and contribute to the design of clean utilities, process equipment, and manufacturing systems across project phases, including development of engineering deliverables and full system design.

Salas O'Brien

Process Engineer

Raleigh, NC · On-site

Support and contribute to the design of clean utilities, process equipment, and manufacturing systems across project phases, including development of engineering deliverables and full system design.

CRB

Process Engineer II

Raleigh, NC · On-site

Participate in basic project system design programming with support from Lead or Senior Engineer ... Proficient with basic coordination with construction trade partners, vendors, and manufacturers ...

8 Rivers

Senior Process Engineer

Durham, NC · On-site

$100K - $130K/yr

Opportunity 8 Rivers is seeking a Senior Process Engineer to design, optimize and commercialize a portfolio of innovative energy technologies and project development opportunities. This role is ideal ...

CRB

Process Engineer II

Raleigh, NC

Participate in basic project system design programming with support from Lead or Senior Engineer ... Proficient with basic coordination with construction trade partners, vendors, and manufacturers ...

CRB

Process Engineer II

Raleigh, NC · On-site

Participate in basic project system design programming with support from Lead or Senior Engineer ... Proficient with basic coordination with construction trade partners, vendors, and manufacturers ...

CRB

Senior Process Engineer - Liquid Systems

Raleigh, NC · On-site

$101K - $130K/yr

We are seeking a Senior Process Engineer with deep expertise in liquid processing systems within ... Lead the design and development of liquid processing systems for food and beverage manufacturing ...

CRB

Senior Process Engineer - Liquid Systems

Raleigh, NC

$101K - $130K/yr

We are seeking a Senior Process Engineer with deep expertise in liquid processing systems within ... Lead the design and development of liquid processing systems for food and beverage manufacturing ...

CRB

Senior Process Engineer - Liquid Systems

Raleigh, NC · On-site

$101K - $130K/yr

We are seeking a Senior Process Engineer with deep expertise in liquid processing systems within ... Lead the design and development of liquid processing systems for food and beverage manufacturing ...

CRB

Senior Process Engineer - Liquid Systems

Raleigh, NC

$101K - $130K/yr

We are seeking a Senior Process Engineer with deep expertise in liquid processing systems within ... Lead the design and development of liquid processing systems for food and beverage manufacturing ...

CRB

Senior Process Engineer - Liquid Systems

Raleigh, NC · On-site

$101K - $130K/yr

We are seeking a Senior Process Engineer with deep expertise in liquid processing systems within ... Lead the design and development of liquid processing systems for food and beverage manufacturing ...

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All JobsManufacturing Process Engineer JobsSenior Manufacturing Process Engineer JobsSenior Manufacturing Process Engineer Jobs in Raleigh, NC

Senior Manufacturing Process Engineer information

See Raleigh, NC salary details

$72.9K

$117.7K

$165.7K

How much do senior manufacturing process engineer jobs pay per year?

As of Jul 23, 2026, the average yearly pay for senior manufacturing process engineer in Raleigh, NC is $117,735.00, according to ZipRecruiter salary data. Most workers in this role earn between $101,100.00 and $130,700.00 per year, depending on experience, location, and employer.

What are the main challenges a Senior Manufacturing Process Engineer faces when implementing process improvements?

One of the primary challenges Senior Manufacturing Process Engineers encounter is balancing the need for process innovation with maintaining production efficiency and product quality. Implementing new technologies or methodologies often requires extensive cross-functional collaboration, training, and sometimes overcoming resistance to change from team members. Additionally, ensuring that process improvements comply with industry regulations and safety standards can add complexity. However, these challenges provide valuable opportunities to develop leadership skills and drive significant impact within the organization.

What are the key skills and qualifications needed to thrive as a Senior Manufacturing Process Engineer, and why are they important?

To thrive as a Senior Manufacturing Process Engineer, you need a strong background in engineering principles, process optimization, and manufacturing systems, typically with a bachelor's or master's degree in engineering and relevant industry experience. Familiarity with CAD/CAM software, Lean Six Sigma methodologies, and statistical process control tools is highly valued, along with certifications such as Six Sigma Green or Black Belt. Exceptional problem-solving abilities, leadership, and effective communication are crucial soft skills for driving process improvements and collaborating across teams. These skills ensure efficient production, high product quality, and continuous operational enhancements in a competitive manufacturing environment.

What does a Senior Manufacturing Process Engineer do?

A Senior Manufacturing Process Engineer is responsible for designing, analyzing, and improving manufacturing processes to increase efficiency, quality, and safety in production environments. They lead projects to implement new technologies, troubleshoot process issues, and optimize workflows. They also work closely with cross-functional teams to ensure that products meet industry standards and regulatory requirements. Additionally, they mentor junior engineers and support continuous improvement initiatives within the organization.

What is the difference between Senior Manufacturing Process Engineer vs Manufacturing Engineer?

AspectSenior Manufacturing Process EngineerManufacturing Engineer
Required CredentialsBachelor's degree in engineering, 5+ years experience, possibly certifications like Six SigmaBachelor's degree in engineering or related field, 1-3 years experience
Work EnvironmentOversees process improvements, leads projects, collaborates with cross-functional teamsSupports manufacturing operations, implements process changes, troubleshoots production issues
Employer & Industry UsageUsed in manufacturing plants, automotive, aerospace, electronics industriesCommon in similar industries, entry to mid-level roles in manufacturing

The main difference is that a Senior Manufacturing Process Engineer typically has more experience, takes on leadership roles, and oversees complex process improvements, while a Manufacturing Engineer focuses on supporting and implementing manufacturing processes at a more operational level.

What are popular job titles related to Senior Manufacturing Process Engineer jobs in Raleigh, NC? For Senior Manufacturing Process Engineer jobs in Raleigh, NC, the most frequently searched job titles are:
What job categories do people searching Senior Manufacturing Process Engineer jobs in Raleigh, NC look for? The top searched job categories for Senior Manufacturing Process Engineer jobs in Raleigh, NC are:
What cities near Raleigh, NC are hiring for Senior Manufacturing Process Engineer jobs? Cities near Raleigh, NC with the most Senior Manufacturing Process Engineer job openings:
Senior Manufacturing Process Engineer jobs near you
Infographic showing various Senior Manufacturing Process Engineer job openings in Raleigh, NC as of July 2026, with employment types broken down into 93% Full Time, and 7% Contract. Highlights an 93% In-person, and 7% Hybrid job distribution, with an average salary of $117,735 per year, or $56.6 per hour.
Specialist Manufacturing - Process Owner - Upstream / Downstream / Services

Specialist Manufacturing - Process Owner - Upstream / Downstream / Services

Amgen

Holly Springs, NC • On-site

$63K - $84K/yr

Other

Posted 12 days ago

Job description

Career Category
Manufacturing
Job Description
HOW MIGHT YOU DEFY IMAGINATION?
You've worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience, and passion to work toward your goals? At Amgen, our shared mission-to serve patients-drives all that we do. It is key to our becoming one of the world's leading biotechnology companies, reaching over 10 million patients worldwide. Come do your best work alongside other innovative, driven professionals in this meaningful role.
Be part of Amgen's newest and most advanced drug substance manufacturing plant. When completed, the Amgen FleX Batch facility will combine the latest in disposable technologies with traditional stainless-steel equipment to allow for maximum flexibility in operations. The FleX Batch facility will not only feature the best in-class drug substance manufacturing technologies with embedded industry 4.0 capabilities, but it will also integrate sustainability innovations to reduce carbon and waste, as part of Amgen's plan to be a carbon-neutral company by 2027.
Specialist Manufacturing - Process Owner - Upstream / Downstream / Services (Multiple Positions)
Live
What You Will Do
In this vital role, you will serve as a Process Owner within the Manufacturing Support organization at Amgen North Carolina (ANC). The Process Owner serves as a technical process steward and key interface between Manufacturing Operations and support organizations. This role is responsible for supporting manufacturing execution through technical process ownership, floor support, operational readiness activities, process governance, manufacturing change implementation support, and continuous improvement initiatives.
This position may support one of the following manufacturing areas depending on business needs and organizational assignment: Upstream Manufacturing, Downstream Manufacturing, or Manufacturing Services (Raw Material Dispensing and Solution Preparation).
  • Serve as the technical process owner for assigned manufacturing processes, equipment, and unit operations.
  • Provide manufacturing floor support, troubleshooting assistance, and hypercare during routine manufacturing operations, process changes, startup activities, and first-time executions.
  • Support operational readiness activities including water runs, dry runs, equipment readiness verification, and Electronic Batch Record (EBR) testing support.
  • Partner with Manufacturing Operations to support reliable, compliant, and efficient manufacturing execution.
  • Monitor process performance and identify opportunities for process optimization, operational improvement, and risk reduction.
  • Support manufacturing-related change controls associated with process, equipment, procedural, and operational improvements.
  • Author, revise, review, and maintain manufacturing SOPs, forms, and other GMP documentation.
  • Ensure manufacturing processes are effectively translated into SOPs, manufacturing workflows, training materials, and associated digital manufacturing processes.
  • Provide technical input to manufacturing risk assessments and support identification and mitigation of process, equipment, procedural, and operational risks.
  • Participate in root cause analysis (RCA) activities and provide technical process expertise to support manufacturing investigations, major deviations, and quality events.
  • Support CAPA applicability assessments, CAPA implementation activities, and CAPA effectiveness checks.
  • Partner with Process Development to support process overviews, knowledge transfer activities, and facility fit assessments.
  • Partner with Supply Chain, Manufacturing, and Engineering to support material readiness and Bill of Material (BOM) alignment, including single-use assemblies and consumables.
  • Support MES and EBR activities by providing process expertise and manufacturing representation.
  • Participate in inspection readiness activities and support audits as required.
  • Appropriately escalate process, operational, quality, and compliance concerns.

Win
What We Expect of You
Basic Qualifications
  • Doctorate degree and 2 years of biotechnology operations experience OR
  • Master's degree in Engineering, Biology, Chemistry, Biochemistry, or related field and 4 years of biotechnology operations experience OR
  • Bachelor's degree and 6 years of biotechnology operations experience OR
  • Associate's degree and 10 years of biotechnology operations experience OR
  • High school diploma / GED and 12 years of biotechnology operations experience
Preferred Qualifications
  • Technical expertise in Upstream Manufacturing, Downstream Manufacturing, or Manufacturing Services (Raw Material Dispensing and Solution Preparation).
  • Strong technical knowledge of drug substance manufacturing processes, equipment, and unit operations.
  • Experience supporting GMP manufacturing operations in a biotechnology or pharmaceutical environment.
  • Experience supporting manufacturing floor operations, troubleshooting, and hypercare activities.
  • Experience supporting operational readiness activities including water runs, dry runs, equipment testing, and startup support.
  • Experience authoring and maintaining GMP documentation including SOPs and manufacturing procedures.
  • Experience supporting manufacturing change controls and implementation activities.
  • Experience participating in risk assessments, root cause analyses, investigations, and CAPA implementation activities.
  • Experience supporting CAPA applicability assessments and effectiveness checks.
  • Experience supporting Manufacturing Execution Systems (MES) and Electronic Batch Records (EBRs) within a GMP manufacturing environment.
  • Knowledge of single-use technologies and Bill of Material (BOM) structures.
  • Strong technical writing, communication, problem-solving, and organizational skills.

Thrive
As we work to develop treatments that take care of others, we also work to care for our teammates' professional and personal growth and well-being through comprehensive benefits, career development opportunities, and a collaborative culture.
Salary Range
107,545.40USD -145,502.60 USD

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