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Senior Cra Jobs in Colorado (NOW HIRING)

Icon plc

Senior Clinical Research Associate

Denver, CO · Hybrid

$110K - $138K/yr

This Sr. CRA role will support the client's Oncology clinical trials to ensure data integrity, subject safety, andinspectionreadiness at the clinical investigative sites. Responsibilities: * Perform ...

ICON

Senior Clinical Research Associate

Denver, CO · On-site +1

$110K - $138K/yr

This Sr. CRA role will support the client's Oncology clinical trials to ensure data integrity, subject safety, and inspection readiness at the clinical investigative sites. Responsibilities:

Gunnison County, CO

Senior Accountant

Gunnison, CO · On-site

$7.3K - $8.9K/mo

... CRA - Empower Retirement. • 457(b) Up to a 3% Employer Contribution match • Discounted Pet Insurance, and Gym Memberships Job Summary The Senior Accountant provides advanced professional ...

GUNNISON COUNTY

Senior Accountant

Gunnison, CO · On-site

$88K - $107K/yr

... to CRA - Empower Retirement. 401(a) 3% Employer Contribution match Voluntary 457(b) Pre-tax or ... The Senior Accountant provides advanced professional accounting support to the Chief Financial ...

Gunnison County

Senior Accountant

Gunnison, CO · On-site

$88K - $107K/yr

Mandatory 401(a) 3% Contribution to CRA - Empower Retirement. * 401(a) 3% Employer Contribution ... Discounted Pet Insurance, and Gym Memberships Job Summary The Senior Accountant provides advanced ...

Tersus Solutions

Senior Accountant

Englewood, CO · On-site

$73K - $91K/yr

The Role Reporting to the VP of Finance, the Senior Accountant will own day-to-day accounting ... Prepare Canadian GST/HST invoicing and filings and maintain CRA account compliance. * Support cross ...

Workday, Inc.

Sr. Principal, GRC

Boulder, CO · On-site

$196K - $287K/yr

... CRA). Enable and maintain Workday's Public Sector offerings through certifications, continuous ... or in a Sr. Principal, GRC-related occupation. 7 years (84 months) of experience in EMEA ...

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All JobsCra JobsSenior Cra JobsSenior Cra Jobs in Colorado

Senior Cra information

See Colorado salary details

$37.9K

$99.2K

$150.9K

How much do senior cra jobs pay per year?

As of Aug 17, 2026, the average yearly pay for senior cra in Colorado is $99,173.00, according to ZipRecruiter salary data. Most workers in this role earn between $65,700.00 and $134,600.00 per year, depending on experience, location, and employer.

What is a senior clinical research associate (CRA)?

Senior Clinical Research Associates (Senior CRAs) are experienced professionals responsible for overseeing and monitoring clinical trials to ensure compliance with regulatory guidelines, protocols, and good clinical practice. They play a key role in managing study sites, reviewing data, and ensuring the integrity and quality of clinical research. Senior CRAs also mentor junior staff, resolve complex issues, and maintain effective communication between sponsors, sites, and regulatory bodies. Their expertise helps ensure that clinical trials are conducted safely and efficiently.

How does a senior clinical research associate (CRA) typically collaborate with site staff and project teams during a clinical trial?

A Senior CRA regularly works with site staff, including investigators and coordinators, to ensure clinical trials are conducted according to protocol, regulatory requirements, and Good Clinical Practice (GCP) guidelines. They serve as a key liaison, communicating study updates, addressing site concerns, and providing training when needed. Additionally, Senior CRAs often collaborate with project managers, data managers, and other CRAs to monitor progress, resolve issues, and ensure data integrity. This teamwork is critical for maintaining study timelines and overall trial quality.

What are the key skills and qualifications needed to thrive as a senior clinical research associate (CRA), and why are they important?

To thrive as a Senior Clinical Research Associate, you need deep knowledge of clinical trial protocols, regulatory guidelines (such as GCP), and several years of hands-on experience in clinical monitoring. Familiarity with electronic data capture (EDC) systems, CTMS platforms, and certifications like ACRP or SOCRA are commonly required. Excellent organizational skills, attention to detail, and effective communication are soft skills that set top candidates apart. These skills ensure trial integrity, regulatory compliance, and smooth collaboration among sponsors, sites, and teams.

What is the difference between Senior Cra vs Clinical Research Associate?

AspectSenior CraClinical Research Associate
Required CredentialsBachelor's degree, experience in clinical trials, often some certificationsBachelor's degree, entry-level to mid-level experience, some certifications
Work EnvironmentLeads monitoring activities, manages sites, mentors junior staffPerforms site monitoring, data collection, and compliance checks
Employer & Industry UsagePharmaceutical companies, CROs, biotech firmsPharmaceutical companies, CROs, biotech firms

The main difference between a Senior Cra and a Clinical Research Associate is experience level and responsibilities. Senior Cras typically oversee monitoring activities, mentor junior staff, and handle more complex tasks, while Clinical Research Associates focus on site monitoring and data collection. Both roles are essential in clinical trials and share similar industry environments and credentials.

Is it hard to get a senior CRA job?

Securing a senior Clinical Research Associate (CRA) position can be competitive, often requiring several years of experience in clinical trials, strong knowledge of Good Clinical Practice (GCP), and relevant certifications. Candidates with a proven track record in monitoring, regulatory compliance, and familiarity with clinical trial management systems tend to have better prospects.

What does a senior clinical research associate do?

A senior clinical research associate (CRA) oversees and monitors clinical trials to ensure compliance with protocols, Good Clinical Practice (GCP), and regulatory requirements. They coordinate with study sites, review data quality, and may mentor junior staff, often using electronic data capture systems and requiring relevant certifications like a CRA certification. Their role is essential in ensuring the integrity and accuracy of clinical trial data.

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The most popular types of Cra jobs in Colorado are:

What are popular job titles related to Senior Cra jobs in Colorado?

For Senior Cra jobs in Colorado, the most frequently searched job titles are:

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The top searched job categories for Senior Cra jobs in Colorado are:

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Senior Cra jobs near you
Infographic showing various Senior Cra job openings in Colorado as of August 2026, with employment types broken down into 90% Full Time, 7% Part Time, 1% Temporary, and 2% Contract. Highlights an 81% Physical, 6% Hybrid, and 13% Remote job distribution, with an average salary of $99,173 per year, or $47.7 per hour.

Senior Clinical Research Associate

Icon plc

Denver, CO • Hybrid

$110K - $138K/yr

Full-time

Medical, Dental, Vision, Life, Retirement

Re-posted 6 days ago

Job description

Senior Clinical Research Associate - Oncology Phase I - Denver, CO

ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster.


As a values-driven organisation, integrity, collaboration, agility, and inclusion are at the heart of how we work and interact with each other, customers, patients and suppliers.


The Sr. Clinical Research Associate (Sr. CRA) willbe responsible forperforming investigative site management and monitoring activities throughout the clinical trial lifecycle. This Sr. CRA role will support the client's Oncology clinical trials to ensure data integrity, subject safety, andinspectionreadiness at the clinical investigative sites.

Responsibilities:

  • Perform site management activities to support the client's Oncology site successandmaintainacontinuous state of inspection readiness

  • Act as the primary contactandfacilitateefficientcommunications between the client's clinical trial team and the sites

  • Perform remote and on-sitemonitoring/co-monitoringvisits (Site Qualification Visits, Site Initiation Visits, Interim Monitoring Visits and Close-Out Visits) to ensure data integrity and subject safety in the client's trials

  • May perform oversight activities to assess monitoring quality and train/mentor less experienced CRAs

  • Promptly document monitoring activitiesandsubmit/approvevisit reports

  • Manage site essential document collection and TMF reconciliation with site files

  • Support sites with local Institutional Review Board (IRB)/Ethics Committee (EC) submissions and confirm approvals

  • Regularly review site Key Risk Indicator (KRI)metrics,issuesandaction items to detect trends and ensure prompt resolution

  • Independentlydeterminerootcauses and develop/implement site Corrective Action and Preventive Action (CAPA) plans

  • Deliver training to ensure sitescomply withthe protocol, Standard Operating Procedures (SOPs), Good Clinical Practices (GCPs)and regulations

  • Support sites and the client's regulatory inspections

  • Contribute to site identification; drive site feasibility and qualification progress; and support site activationactivities

  • Lead site engagement initiatives and foster relationships with key Oncology sites and networks

Qualifications

  • Bachelor's degree (scientific field preferred)

  • 5+yearsmonitoringclinicaltrials independently conducting on-site and remote monitoring visits. Atleast 2 years monitoring solid tumor clinical trials.

  • 1+ years early development oncology trial experience and/or Phase III Oncology trial experience

  • Solidtumorclinicaltrial experience is required

  • Experience utilizing Veeva systems is highly preferred

  • Demonstrated experiencedeveloping/maintainingsiterelationships and securing compliance

  • ExpertiseinGxPsandOncology monitoring techniques (including Risk-Based Monitoring) and terminology

  • Experience collaborating with sitesfrominitialengagementthrough close-out phases

  • Experience activating sites

  • Experience training site staff

  • Experience supporting sites and/or sponsors in regulatory inspections

  • Experience working within a Functional Services (or in-house) monitoring model is preferred

  • Willing to travel up to 50%


Employment with ICON is contingent upon having the legal right to work in the country where the role is based.


Rewards & Benefits

ICON offers a competitive and comprehensive total rewards package designed to support your health, wellbeing, and career development.


Benefits may include:

  • Competitive base salary and performance related incentives
  • Health and wellbeing programmes including medical, dental, and vision coverage where applicable
  • Retirement and pension plans
  • Life assurance and disability coverage
  • Employee assistance programmes and wellbeing resources
  • Learning and development opportunities through structured training and career pathways

Benefits may vary depending on role and location.


Visit our careers site to read more about the benefits ICON offers.


Inclusion and Accessibility

ICON is an equal opportunity employer. We are committed to building an inclusive and accessible workplace where everyone feels valued and supported.


If you require reasonable accommodations during the recruitment process, please let us know or submit a requesthere.

Salary Range

$110,520.00-$138,150.00

Are you a current ICON Employee? Please click here to apply

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