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Senior Clinical Project Manager Jobs (NOW HIRING)

Our FSO team is seeking an Oncology Sr. Clinical Project Manager or Project Manager II to join our growing team. This role requires 3-5 + years of global project management experience , with ...

Clinical Project Manager

Durham, NC · On-site

$85K - $120K/yr

As a Clinical Project Manager, you will play a critical role in leading cross-functional teams, ensuring adherence to project timelines, budgets, and quality standards, while collaboratively working ...

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Senior Clinical Project Manager information

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$52K

$115.6K

$201K

How much do senior clinical project manager jobs pay per year?

As of Aug 16, 2026, the average yearly pay for senior clinical project manager in the United States is $115,579.00, according to ZipRecruiter salary data. Most workers in this role earn between $90,500.00 and $143,000.00 per year, depending on experience, location, and employer.

What is a senior clinical project manager?

A Senior Clinical Project Manager is a professional responsible for overseeing and managing clinical trials and research projects within the pharmaceutical, biotechnology, or medical device industries. They coordinate all aspects of a clinical study, including planning, execution, budgeting, and compliance with regulatory requirements. Senior Clinical Project Managers lead cross-functional teams, communicate with stakeholders, and ensure that clinical trials are completed on time, within scope, and according to quality standards. Their expertise is crucial for the successful development of new treatments and therapies.

What are the key skills and qualifications needed to thrive as a senior clinical project manager?

To thrive as a Senior Clinical Project Manager, you need in-depth knowledge of clinical research, regulatory requirements, project management methodologies, and typically a degree in life sciences or a related field. Familiarity with clinical trial management systems (CTMS), electronic data capture (EDC) platforms, and certifications such as PMP or equivalent are commonly required. Strong leadership, problem-solving, and communication skills help manage cross-functional teams and stakeholder expectations. These skills and qualifications ensure efficient trial execution, regulatory compliance, and the successful delivery of clinical projects within timelines and budgets.

How does a senior clinical project manager typically collaborate with cross-functional teams throughout a clinical trial?

A Senior Clinical Project Manager plays a pivotal role in coordinating cross-functional teams, such as clinical operations, data management, biostatistics, regulatory affairs, and vendors. They facilitate regular meetings, ensure effective communication, and resolve any interdepartmental issues that may arise during the study. By fostering collaboration and aligning team objectives, they help maintain timelines, manage resources, and ensure the trial progresses smoothly and compliantly. This collaborative approach is essential for the successful execution and delivery of clinical projects.

What does a senior clinical project manager do?

As a senior clinical project manager, your responsibilities center around the management of a clinical trial team. You assign projects, ensure the success of team activities, and enforce company regulations. Your duties include staying within the scope of a budget while carrying out a clinical trial. You manage your team through each study as you plan out their responsibilities, keeping the project on track and cost-effective. As a senior clinical project manager, you create reports on the efficiency and progress of each clinical trial.

What is the difference between Senior Clinical Project Manager vs Clinical Project Manager?

AspectSenior Clinical Project ManagerClinical Project Manager
Required CredentialsTypically requires 5+ years of experience, advanced certifications (e.g., PMP), and strong leadership skillsUsually requires 2-4 years of experience, relevant certifications, and foundational project management skills
Work EnvironmentLeads multiple projects, manages teams, and interacts with senior stakeholdersManages individual projects, coordinates with teams, and reports to senior managers
Employer & Industry UsageCommonly employed in pharmaceutical, biotech, and CRO companies for complex projectsUsed across similar industries for managing clinical trials at various scales

The main difference between a Senior Clinical Project Manager and a Clinical Project Manager lies in experience, leadership responsibilities, and project scope. Senior roles involve overseeing multiple projects and guiding teams, while Clinical Project Managers focus on managing specific clinical trials. Both roles require relevant certifications and industry experience, but the senior position demands more strategic oversight and leadership skills.

What cities are hiring for Senior Clinical Project Manager jobs?

Cities with the most Senior Clinical Project Manager job openings:

Who are the top companies hiring for Senior Clinical Project Manager jobs?

The top employers for Senior Clinical Project Manager jobs are:

What states have the most Senior Clinical Project Manager jobs?

States with the most job openings for Senior Clinical Project Manager jobs include:

Infographic showing various Senior Clinical Project Manager job openings in the United States as of August 2026, with employment types broken down into 1% As Needed, 86% Full Time, 12% Part Time, and 1% Contract. Highlights an 94% Physical, 2% Hybrid, and 4% Remote job distribution, with an average salary of $115,579 per year, or $55.6 per hour.

Sr Clinical Project Manager - Remote US

Mckesson

Concord, NC • Remote

Full-time

Posted 15 days ago


McKesson rating

7.9

Company rating: 7.9 out of 10

Based on 209 frontline employees who took The Breakroom Quiz

47th of 86 rated pharmaceutical


Job description

It's More Than a Career, It's a Mission.


Our people are the foundation of our success. By joining our growing team at Sarah Cannon Research Institute (SCRI), a subsidiary of McKesson, you will have the opportunity to become part of one of the largest community-based cancer programs to advance oncology treatments and improve outcomes for cancer patients across the globe. We look for mission-driven candidates who have a desire to advance the fight against cancer and make a difference in the lives of patients diagnosed with cancer every day.

Our Mission


People who live with cancer - those who work to prevent it, fight it, and survive it - are at the heart of every decision we make. Bringing the most innovative medical minds together with the most passionate caregivers in their communities, we are transforming care and personalizing treatment. Through clinical excellence and cutting-edge research, SCRI is redefining cancer care around the world.

Our Sr Clinical Project Manager is responsible for management of multiple projects (including global projects) throughoutall lifecycle phases. Ensures that all project work is completed to the client expectations, ensuringquality deliverables on time and within budget and in accordance with SOPs, ICH GCP, applicableregulations, policies and practices. Serves as the principal liaison with clients to ensure effective andtimely communication of project progress, issues, and plans for resolution of those issues.

Providesleadership in the development of clinical trials and related documents. Works closely and effectivelywith cross-functional teams. Mentors and assists in the development of project team members,participates in the PM department initiatives, process improvement and training programs. Providesstrategy and input in business development proposals and attends bid defenses.

This is a remote position based in the US; relocation assistance and visa sponsorship are not available.

Qualifications for success include:

  • Bachelor Degree required, Master's Degree preferred

  • 5-7+ years' professional experience in clinical research, pharmaceutical, or life sciences industries as a Project Manager, leading and directing other team members

  • Full understanding of drug development process with experience with the critical elements for success in clinical trials; participation in and contribution to all activities

  • Experience reviewing protocols, programs, and assess the success of a project

  • Experience with budgeting, forecasting, and resource utilization for the clinical trial

About Sarah Cannon Research Institute


Sarah Cannon Research Institute (SCRI) is one of the world's leading oncology research organizations conducting community-based clinical trials. Focused on advancing therapies for patients over the last three decades, SCRI is a leader in drug development. In 2022, SCRI formed a joint venture with former US Oncology Research to expand clinical trial access across the country. It has conducted more than 850 first-in-human clinical trials since its inception and contributed to pivotal research that has led to the majority of new cancer therapies approved by the FDA in the past decade. SCRI's research network brings together more than 1,300 physicians who are enrolling patients into clinical trials at more than 200 locations in 20+ states across the U.S. Please click here to learn more about our research offerings.
We care about the well-being of the patients and communities we serve, and that starts with caring for our people. That's why we have a Total Rewards package that includes comprehensive benefits to support physical, mental, and financial well-being. Our Total Rewards offerings serve the different needs of our diverse colleague population and ensure they are the healthiest versions of themselves. For more information regarding benefits through our parent company, McKesson, please click here.
As part of Total Rewards, we are proud to offer a competitive compensation package. This is determined by several factors, including performance, experience and skills, equity, regular job market evaluations, and geographical markets. In addition to base pay, other compensation, such as an annual bonus or long-term incentive opportunities may be offered.

McKesson has become aware of online recruiting-related scams in which individuals who are not affiliated with or authorized by McKesson are using McKesson's (or affiliated entities, like CoverMyMeds or RxCrossroads) name in fraudulent emails, job postings or social media messages. In light of these scams, please bear the following in mind:
McKesson Talent Advisors will never solicit money or credit card information in connection with a McKesson job application.


McKesson Talent Advisors do not communicate with candidates via online chatrooms or using email accounts such as Gmail or Hotmail. Note that McKesson does rely on a virtual assistant (Gia) for certain recruiting-related communications with candidates.

McKesson job postings are posted on our career site: careers.mckesson.com.

We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.


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