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Senior Clinical Project Manager Jobs in Raleigh, NC

IQVIA

Senior Clinical Project Manager, CNS

Durham, NC

$93K - $232K/yr

We are seeking a US-based Senior Clinical Project Manager with proven experience in Central Nervous System (CNS) clinical trials to join IQVIA Biotech. This role is ideal for a seasoned project ...

IQVIA

Senior Clinical Project Manager

Durham, NC · On-site

... Management is focused on project delivery, productivity and quality resulting in strong financial performance and customer satisfaction. Clinical Project leads run their own studies. The Senior ...

IQVIA, Inc.

Senior Clinical Project Manager

Durham, NC · On-site

... Management is focused on project delivery, productivity and quality resulting in strong financial performance and customer satisfaction. Clinical Project leads run their own studies. The Senior ...

IQVIA

Senior Clinical Project Manager

Durham, NC

... Management is focused on project delivery, productivity and quality resulting in strong financial performance and customer satisfaction. Clinical Project leads run their own studies. The Senior ...

IQVIA

Senior Clinical Project Manager- CNS

Durham, NC · On-site

... Management is focused on project delivery, productivity and quality resulting in strong financial performance and customer satisfaction. Clinical Project leads run their own studies. The Senior ...

Pluto Health

Clinical Project Manager

Durham, NC · On-site

$85K - $120K/yr

As a Clinical Project Manager, you will play a critical role in leading cross-functional teams, ensuring adherence to project timelines, budgets, and quality standards, while collaboratively working ...

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Senior Clinical Project Manager information

See Raleigh, NC salary details

$50.5K

$112.3K

$195.4K

How much do senior clinical project manager jobs pay per year?

As of Aug 7, 2026, the average yearly pay for senior clinical project manager in Raleigh, NC is $112,346.00, according to ZipRecruiter salary data. Most workers in this role earn between $88,000.00 and $139,000.00 per year, depending on experience, location, and employer.

What is a senior clinical project manager?

A Senior Clinical Project Manager is a professional responsible for overseeing and managing clinical trials and research projects within the pharmaceutical, biotechnology, or medical device industries. They coordinate all aspects of a clinical study, including planning, execution, budgeting, and compliance with regulatory requirements. Senior Clinical Project Managers lead cross-functional teams, communicate with stakeholders, and ensure that clinical trials are completed on time, within scope, and according to quality standards. Their expertise is crucial for the successful development of new treatments and therapies.

What are the key skills and qualifications needed to thrive as a senior clinical project manager?

To thrive as a Senior Clinical Project Manager, you need in-depth knowledge of clinical research, regulatory requirements, project management methodologies, and typically a degree in life sciences or a related field. Familiarity with clinical trial management systems (CTMS), electronic data capture (EDC) platforms, and certifications such as PMP or equivalent are commonly required. Strong leadership, problem-solving, and communication skills help manage cross-functional teams and stakeholder expectations. These skills and qualifications ensure efficient trial execution, regulatory compliance, and the successful delivery of clinical projects within timelines and budgets.

How does a senior clinical project manager typically collaborate with cross-functional teams throughout a clinical trial?

A Senior Clinical Project Manager plays a pivotal role in coordinating cross-functional teams, such as clinical operations, data management, biostatistics, regulatory affairs, and vendors. They facilitate regular meetings, ensure effective communication, and resolve any interdepartmental issues that may arise during the study. By fostering collaboration and aligning team objectives, they help maintain timelines, manage resources, and ensure the trial progresses smoothly and compliantly. This collaborative approach is essential for the successful execution and delivery of clinical projects.

What does a senior clinical project manager do?

As a senior clinical project manager, your responsibilities center around the management of a clinical trial team. You assign projects, ensure the success of team activities, and enforce company regulations. Your duties include staying within the scope of a budget while carrying out a clinical trial. You manage your team through each study as you plan out their responsibilities, keeping the project on track and cost-effective. As a senior clinical project manager, you create reports on the efficiency and progress of each clinical trial.

What is the difference between Senior Clinical Project Manager vs Clinical Project Manager?

AspectSenior Clinical Project ManagerClinical Project Manager
Required CredentialsTypically requires 5+ years of experience, advanced certifications (e.g., PMP), and strong leadership skillsUsually requires 2-4 years of experience, relevant certifications, and foundational project management skills
Work EnvironmentLeads multiple projects, manages teams, and interacts with senior stakeholdersManages individual projects, coordinates with teams, and reports to senior managers
Employer & Industry UsageCommonly employed in pharmaceutical, biotech, and CRO companies for complex projectsUsed across similar industries for managing clinical trials at various scales

The main difference between a Senior Clinical Project Manager and a Clinical Project Manager lies in experience, leadership responsibilities, and project scope. Senior roles involve overseeing multiple projects and guiding teams, while Clinical Project Managers focus on managing specific clinical trials. Both roles require relevant certifications and industry experience, but the senior position demands more strategic oversight and leadership skills.

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Senior Clinical Project Manager jobs near you
Infographic showing various Senior Clinical Project Manager job openings in Raleigh, NC as of August 2026, with employment types broken down into 88% Full Time, 11% Part Time, and 1% Contract. Highlights an 84% Physical, 3% Hybrid, and 13% Remote job distribution, with an average salary of $112,346 per year, or $54 per hour.

Senior Clinical Project Manager

Azurity Pharmaceuticals - US

Raleigh, NC • Hybrid

Full-time

Posted 4 days ago

Job description

About the Role

The Senior Clinical Project Manager, Clinical Development is responsible for leading the planning, execution, oversight, and delivery of domestic and/or global postmarketing required clinical trials. The Sr. CPM serves as the operational leader for assigned studies, partnering cross-functionally with Medical/Drug Safety, Regulatory, Data Management, Quality, and external vendors to ensure clinical trials are delivered on time, within budget, and in compliance with applicable regulations and quality standards.

 Key Responsibilities

  • Lead the operational execution of assigned domestic or global, multi-center late phase clinical trial(s) including oversight of selected vendor(s)/CRO to ensure accountability, quality, and on time delivery of key project deliverables.
  • Develop and manage study timelines, contract/budget negotiations, and risk mitigation plans to ensure delivery on timeline and financial goals are met.
  • Initiate and manage request for proposal activities for assigned clinical studies or clinical development vendors, including CROs, specialty lab vendors, bioanalytical vendors, etc.
  • Lead study execution team comprised of cross-functional representatives from Regulatory, Drug Safety, Medical, Drug Supply, Data Management, Biostatistics, and Quality to oversee CRO vendors and ensure study excellence.
  • Manage clinical development vendors according to vendor oversight plans.
  • Oversee all study-level data monitoring activities, reviews monitoring visit reports, and conducts Sponsor oversight monitoring visits as required.
  • Responsible for monthly Protocol Deviation (PD) review, including oversight of CRA documentation and collaboration with Medical Monitor for medical review.
  • Prepares and/or reviews study-related study plans/documents; reviews site study documents.
  • Assist in strategic trial design and protocol writing.
  • Strategic country/site selection with program input and ensuring consistency across all clinical projects for therapeutic area.
  • Ensures all clinical trials are executed in compliance with ICH/GCP guidelines/regulations and applicable SOPs: participates in the planning of quality assurance activities and coordinates resolution of audit findings; ensures audit-ready condition of clinical trial documentation including central clinical files, Trial Master File (TMF), and clinical trial registry submissions.
  • Ensure inspection readiness and compliance with ICH-GCP, FDA, EMA, and applicable regulatory requirements.

Required Skills and Experience

  • Bachelor's degree in Life Sciences or a related scientific discipline (advanced degree preferred).
  • 8+ years of Clinical Trial / Project Management experience within CRO, biotechnology or pharmaceutical organizations.
  • Demonstrated experience operating at a Senior Clinical Trial Lead or Associate Director level.
  • Proven leadership of global clinical studies and cross-functional project teams.
  • Strong experience managing CROs, vendors, and external partners.
  • Extensive knowledge of ICH-GCP, FDA, EMA, and global clinical trial regulations.
  • Excellent communication, leadership, and project management skills.

 Preferred Qualifications

  • 5+ years' experience of clinical trial management for late phase studies
  • Experience with IMP/clinical drug supply logistics, planning, and labeling activities in late phase studies
  • Effective communicator who can manage multiple priorities while building strong internal relationships across multiple departments

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