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Senior Bioinformatics Software Engineer Jobs in Minnesota

Senior Software Engineer

Saint Paul, MN ยท On-site

$123.50K - $162.80K/yr

Senior Software Engineer Greetings for the day! My name is Suneetha from Testing Xperts, we are a global staffing, consulting and technology solutions company, offering industry-specific solutions to ...

Senior Software Engineer

Eagan, MN

$124.90K - $164.70K/yr

Senior Software Engineer Location: Eagan, MN Senior Software Engineer Developer will be joining Agile team working on our eLearning platform. This team works on the UI, business and data layers plus ...

Sr Software Engineer

Eden Prairie, MN ยท On-site +1

$124.90K - $164.70K/yr

Senior Software Engineer The Senior Software Engineer position is a key member of R&D Software Engineering Group for Bracco Medical Technologies (BMT) and will develop software for Medical Devices ...

Sr Software Engineer

Eden Prairie, MN ยท Hybrid

$124.90K - $164.70K/yr

Sr Software Engineer(RESTful, SQL) (.Net Developer) Location: Eden Prairie, MN - Hybrid Position Type: Contract Summary: This is a.NET Full Stack Application Development role building and maintaining ...

Sr Software Engineer

Eden Prairie, MN ยท Hybrid

$124.90K - $164.70K/yr

Sr Software Engineer(RESTful, SQL) (.Net Developer) Location: Eden Prairie, MN - Hybrid Position Type: Contract Summary: This is a.NET Full Stack Application Development role building and maintaining ...

Senior Software Engineer

Maple Grove, MN ยท On-site

$125.40K - $165.40K/yr

Nextern is seeking a Senior Software Engineer to join our product realization team. At Nextern, we develop innovative medical technologies and connected solutions that improve patient outcomes and ...

Senior Software Engineer

Maple Grove, MN ยท On-site

$125.40K - $165.40K/yr

Nextern is seeking a Senior Software Engineer to join our product realization team. At Nextern, we develop innovative medical technologies and connected solutions that improve patient outcomes and ...

Senior Software Engineer

Maple Grove, MN ยท On-site

$125.40K - $165.40K/yr

Nextern is seeking a Senior Software Engineer to join our product realization team. At Nextern, we develop innovative medical technologies and connected solutions that improve patient outcomes and ...

Senior Software Engineer

Maple Grove, MN ยท On-site

$125.40K - $165.40K/yr

Nextern is seeking a Senior Software Engineer to join our product realization team. At Nextern, we develop innovative medical technologies and connected solutions that improve patient outcomes and ...

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Showing results 1-20

Senior Bioinformatics Software Engineer information

See Minnesota salary details

$82.8K

$100.2K

$117K

How much do senior bioinformatics software engineer jobs pay per year?

As of May 28, 2026, the average yearly pay for senior bioinformatics software engineer in Minnesota is $100,165.00, according to ZipRecruiter salary data. Most workers in this role earn between $92,600.00 and $107,700.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Senior Bioinformatics Software Engineer, and why are they important?

To thrive as a Senior Bioinformatics Software Engineer, you need a strong background in computer science, biology, and data analysis, often supported by an advanced degree in bioinformatics or a related field. Expertise with programming languages (such as Python, R, or Java), cloud computing, bioinformatics tools, and version control systems is typically required, along with experience using databases and relevant software frameworks. Strong problem-solving skills, collaboration, and effective communication are crucial soft skills for working with multidisciplinary teams and presenting complex data. These combined skills enable the effective development and maintenance of robust software tools that support cutting-edge biological research and data-driven discoveries.

How does a Senior Bioinformatics Software Engineer typically collaborate with cross-functional teams in a research or clinical setting?

Senior Bioinformatics Software Engineers frequently work alongside biologists, data scientists, and clinicians to develop and maintain computational pipelines for data analysis. They play a key role in translating complex biological questions into scalable software solutions, often leading code reviews, mentoring junior developers, and ensuring data integrity. Regular meetings and clear communication are vital, as the role requires aligning technical development with scientific goals and regulatory requirements. This collaborative environment offers opportunities to influence project direction and contribute to impactful discoveries.

What does a Senior Bioinformatics Software Engineer do?

A Senior Bioinformatics Software Engineer designs, develops, and maintains software tools and pipelines to analyze biological data, such as genomic or proteomic information. They work closely with scientists and researchers to understand data requirements and translate them into efficient, scalable computational solutions. Their responsibilities often include coding, troubleshooting, optimizing algorithms, as well as mentoring junior engineers and contributing to project planning. Senior engineers are expected to have strong programming skills, a solid understanding of bioinformatics concepts, and experience working with large biological datasets.

What is the difference between Senior Bioinformatics Software Engineer vs Bioinformatics Software Engineer?

AspectSenior Bioinformatics Software EngineerBioinformatics Software Engineer
Required CredentialsBachelor's or Master's in Bioinformatics, Computer Science, or related field; experience in software development and bioinformatics toolsBachelor's or Master's in Bioinformatics, Computer Science, or related field; less emphasis on extensive experience
Work EnvironmentResearch labs, biotech companies, healthcare institutions, often leading projectsResearch teams, biotech firms, academic settings, supporting bioinformatics analysis
Employer & Industry UsageUsed in biotech, pharma, healthcare, research institutionsCommon in similar industries, often as entry to mid-level roles

The main difference between a Senior Bioinformatics Software Engineer and a Bioinformatics Software Engineer lies in experience and responsibility. Senior roles typically require more advanced skills, leadership, and project management, while entry-level roles focus on supporting bioinformatics analysis and software development. Both roles are vital in biotech and research industries, but senior positions involve greater oversight and strategic input.

What are popular job titles related to Senior Bioinformatics Software Engineer jobs in Minnesota? For Senior Bioinformatics Software Engineer jobs in Minnesota, the most frequently searched job titles are:
What job categories do people searching Senior Bioinformatics Software Engineer jobs in Minnesota look for? The top searched job categories for Senior Bioinformatics Software Engineer jobs in Minnesota are:
What cities in Minnesota are hiring for Senior Bioinformatics Software Engineer jobs? Cities in Minnesota with the most Senior Bioinformatics Software Engineer job openings:
Rsch Pro 2-Informatics

Rsch Pro 2-Informatics

University of Minnesota

Minneapolis, MN โ€ข Hybrid

$57.35K - $60K/yr

Full-time

Medical, Dental, Life, Retirement

Posted 24 days ago


Job description

About the Job
ย 

Summary:
This position involves the testing, evaluation and application of advanced bioinformatics tools for analysis of genomic data. Potential for performing independent genomic experiments at the bench. Working with a team of researchers, the researcher will test both standardized and new software tools used in workflows that integrate different types of genomic and proteomic data. In some cases this researcher will work with collaborators to analyze their data and output results for interpretation and hypothesis generation. Working knowledge and technical understanding of different bioinformatics software is expected, which will enable this researcher to work independently to solve problems related to optimizing software and workflows, as well as application to research data generated by other lab members and collaborators.
This position is available immediately. The work schedule is MondayFriday and is flexible and there is opportunity for a hybrid schedule.
Essential Functions:
50% Run genomic analyses on independent projects or on projects in collaboration with lab members. Routine analyses will include RNAseq, ChIPseq, ATACseq. Specialized projects will include analysis of spatial transcriptomics data of human liver samples.
20% Software and workflow testing, evaluation and optimization
Software tools implemented in the Galaxy platform will be tested and evaluated, adjusting parameters to optimize for best results. Where appropriate, this testing will be carried out independently with minimal input from other research team members. In other cases, new software will be implemented needing testing, and will require consultation and direction from other research team members.
20% Carry out wet bench experiments (standard genomic approaches).
10% Assist in publications and presentations
Assistance will be provided in generating manuscripts for publication, conference presentations and training workshops based on optimized software, workflows and results from their application.

Qualifications
ย 

All required qualifications must be included in the application materials

Required Qualifications:
At minimum, a bachelors degree in bioinformatics, computational biology, molecular biology, or related field is required, plus at least two years of experience OR a combination of education and work experience to equal at least six years. . Demonstrated expertise, both operational and technical, in contemporary bioinformatics software, including software for analysis of RNA-Seq transcriptome data, ChIPseq analysis and quantitative mass spectrometry-based proteomics data and tools for integrating these data types is essential. Proven ability to work with a team of other researchers (biologists, software developers, etc) is also essential. Effective written and verbal communication skills.
Preferred Qualifications:
Experience working at the wet bench and carrying out molecular bioscience research projects is a plus. Experience working in diverse areas of molecular biotechnology, as well as planning and carrying out experiments is also a plus. Experience with spatial transcriptomic platforms or Fiberseq data is also a plus.

About the Department
ย 

BMBB:

The department of Biochemistry, Molecular Biology and Biophysics is committed to understanding the molecular mechanisms of metabolic diseases and cancer; developing novel strategies in biocatalysis and biotechnology; and advancing knowledge through structural biology and molecular biophysics. We organize ourselves into research divisions with emphases onย Chemical and Structural Biology, Metabolic andย Systems Biology, Molecular Biology and Synthetic Biology and Biotechnology. We are housed in new buildings with state-of-the-art research and support facilities.

Pay and Benefits
ย 

Pay Range: $57,345 - $60,000; depending on education/qualifications/experience

Time Appointment: 100% Appointment

Position Type:ย Civil-Service & Non-Faculty Labor Represented Staff

Please visit theย Office of Human Resources website for more information regarding benefit eligibility.

The University offers a comprehensive benefits package that includes:

  • Competitive wages, paid holidays, and generous time off
  • Continuous learning opportunities through professional training and degree-seeking programs supported by theย Regents Tuition Benefit Program
  • Low-cost medical, dental, and pharmacy plans
  • Healthcare and dependent care flexible spending accounts
  • University HSA contributions
  • Disability and employer-paid life insurance
  • Employee wellbeing program
  • Excellent retirement plans with employer contribution
  • Public Service Loan Forgiveness (PSLF) opportunity
  • Financial counseling servicesย 
  • Employee Assistance Program with eight sessions of counseling at no cost
  • Employee Transit Pass with free or reduced rates in the Twin Cities metro area

While our salary ranges provide a framework, it is important to note that most of the
time, the initial pay may not reach the maximum of the range. This approach ensures
that compensation reflects the value and unique contributions of each candidate while
maintaining equity within our organization. As part of our commitment to fair and
equitable compensation, please be aware that the salary offered to incoming candidates
will be based on their individual credentials and experience.

How To Apply
ย 

Applications must be submitted online. ย To be considered for this position, please click the Apply button and follow the instructions. ย You will be given the opportunity to complete an online application for the position and attach a cover letter and resume.

Additional documents may be attached after application by accessing your "My Job Applications" page and uploading documents in the "My Cover Letters and Attachments" section.

To request an accommodation during the application process, please e-mail employ@umn.edu or call (612) 624-8647.

Diversity
ย 

The University recognizes and values the importance of diversity and inclusion in enriching the employment experience of its employees and in supporting the academic mission.ย  The University is committed to attracting and retaining employees with varying identities and backgrounds.

The University of Minnesota provides equal access to and opportunity in its programs, facilities, and employment without regard to race, color, creed, religion, national origin, gender, age, marital status, disability, public assistance status, veteran status, sexual orientation, gender identity, or gender expression.ย  To learn more about diversity at the U:ย  http://diversity.umn.edu

Employment Requirements
ย 

Any offer of employment is contingent upon the successful completion of a background check. Our presumption is that prospective employees are eligible to work here. Criminal convictions do not automatically disqualify finalists from employment.

About University of Minnesota
ย 

The University of Minnesota, Twin Cities (UMTC)

The University of Minnesota, Twin Cities (UMTC), is among the largest public research universities in the country, offering undergraduate, graduate, and professional students a multitude of opportunities for study and research. Located at the heart of one of the nation's most vibrant, diverse metropolitan communities, students on the campuses in Minneapolis and St. Paul benefit from extensive partnerships with world-renowned health centers, international corporations, government agencies, and arts, nonprofit, and public service organizations.

At the University of Minnesota, we are proud to be recognized by the Star Tribune as a Top Workplace for 2021, as well as by Forbes as Best Employers for Women and one of Americas Best Employers (2015, 2018, 2019, 2023), Best Employer for Diversity (2019, 2020), Best Employer for New Grads (2018, 2019), and Best Employer by State (2019, 2022).