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Bioinformatics Engineer Jobs in Minnesota (NOW HIRING)

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Bioinformatics Engineer information

See Minnesota salary details

$42.1K

$128.4K

$233.6K

How much do bioinformatics engineer jobs pay per year?

As of Jun 12, 2026, the average yearly pay for bioinformatics engineer in Minnesota is $128,355.00, according to ZipRecruiter salary data. Most workers in this role earn between $94,000.00 and $153,800.00 per year, depending on experience, location, and employer.

What is a Bioinformatics Engineer?

A Bioinformatics Engineer is a professional who combines expertise in computer science, statistics, and biology to develop software tools and algorithms for analyzing biological data. They often work with large datasets such as genomic sequences, protein structures, and clinical information to help scientists make sense of complex biological systems. Their work is essential in fields like genomics, personalized medicine, and drug discovery, where managing and interpreting vast amounts of data is crucial. Bioinformatics Engineers may also collaborate with researchers to design experiments and interpret results, bridging the gap between biology and technology.

What are the key skills and qualifications needed to thrive as a Bioinformatics Engineer, and why are they important?

To thrive as a Bioinformatics Engineer, you need a strong background in biology, computer science, and statistics, often supported by a degree in bioinformatics or a related field. Experience with programming languages such as Python or R, familiarity with databases, and knowledge of tools like BLAST, Bioconductor, or next-generation sequencing (NGS) analysis platforms are typically required. Strong problem-solving, analytical thinking, and effective communication skills help you collaborate with interdisciplinary teams and convey complex findings. These skills and qualifications are essential for efficiently analyzing biological data, developing robust computational tools, and advancing research in genomics and life sciences.

What Is Bioinformatics Engineering?

A bioinformatics engineer uses various methods for the analysis of complex biological data such as gene sequence and protein absorption. In this career, your job duties include performing detailed data analysis, developing data queries, and presenting your results back to the research team. The qualifications needed for a career as a bioinformatics engineer include a bachelor’s degree in engineering, statistics, computer science, or mathematics. Some employers prefer a master’s degree as well. You also need strong analytical skills and a good understanding of the biosciences.

What are some common challenges faced by Bioinformatics Engineers when integrating new data sources into existing pipelines?

Bioinformatics Engineers often encounter challenges such as data format inconsistencies, varying quality of datasets, and the need to ensure compatibility with existing analysis pipelines. Integrating new data sources may require custom scripts or tools for parsing and preprocessing, as well as thorough validation to maintain reproducibility and reliability of results. Collaboration with wet-lab scientists and software engineers is essential to clarify data requirements and streamline the integration process.

What is the difference between Bioinformatics Engineer vs Bioinformatics Analyst?

AspectBioinformatics EngineerBioinformatics Analyst
Required CredentialsBachelor's or Master's in Bioinformatics, Computer Science, or related fields; programming skillsBachelor's or Master's in Bioinformatics, Biology, or related fields; data analysis skills
Work EnvironmentResearch labs, biotech companies, pharmaceutical firmsResearch institutions, healthcare organizations, biotech companies
Employer & Industry UsageDevelops tools, pipelines, and software for biological data analysisInterprets data, performs statistical analysis, and reports findings

While both roles require a background in bioinformatics and involve working with biological data, Bioinformatics Engineers focus on developing software and tools, whereas Bioinformatics Analysts primarily analyze and interpret data to support research and decision-making.

What job categories do people searching Bioinformatics Engineer jobs in Minnesota look for? The top searched job categories for Bioinformatics Engineer jobs in Minnesota are:
Infographic showing various Bioinformatics Engineer job openings in Minnesota as of June 2026, with employment types broken down into 84% Full Time, 14% Part Time, and 2% Contract. Highlights an 87% In-person, 2% Hybrid, and 11% Remote job distribution, with an average salary of $128,355 per year, or $61.7 per hour.
Bioinformatician - Bioinformatician - Biomedical Imaging Resource (BIR) - 1 Year Limited Tenure

Bioinformatician - Bioinformatician - Biomedical Imaging Resource (BIR) - 1 Year Limited Tenure

Mayo Clinic

Rochester, MN

Full-time

Medical, Dental, Vision, Retirement

Posted 5 days ago


Mayo Clinic rating

7.8

Company rating: 7.8 out of 10

Based on 678 frontline employees who took The Breakroom Quiz

130th of 871 rated healthcare providers


Job description

The Bioinformatician functions as a bioinformatics collaborator who applies bioinformatics expertise to the design, implementation, analysis, interpretation, and reporting of research and clinical genomics studies. The work is performed under the supervision of a Senior Bioinformatician or Principal Bioinformatician. Possesses skills and knowledge in a variety of bioinformatics and computational biology tools and techniques to analyze genomics, proteomics and metabolomics data (omics technologies). Also possesses good programing skills to develop novel analytical tools as needed by projects. Additional optional skills include basic knowledge of statistical methodology. Administrative duties: accurately keep track and record time spent on projects. Maintain documentation of projects with a level of detail enabling the handoff to other bioinformatics staff members.

This is a limited tenure position that has been approved for one year that may have the possibility of turning into a regular position.


This vacancy is not eligible for sponsorship/ we will not sponsor or transfer visas for this position. Also, Mayo Clinic DOES NOT participate in the F-1 STEM OPT extension program.

Additional Information: 

Advanced Skills and Responsibilities: The ideal candidate will demonstrate a strong understanding of automated AI and bioinformatics pipelines, including the ability to evaluate, implement, and support new and experimental software packages for informatics and imaging workflows. This role requires intellectual curiosity and motivation to expand expertise into emerging, data-focused domains as project needs evolve. The candidate will also bring a proven track record of successful technical customer service and consulting, partnering effectively with investigators and stakeholders to translate complex computational approaches into practical, research-ready solutions.

Why Mayo Clinic

Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans - to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.

Benefits Highlights
  • Medical: Multiple plan options.
  • Dental: Delta Dental or reimbursement account for flexible coverage.
  • Vision: Affordable plan with national network.
  • Pre-Tax Savings: HSA and FSAs for eligible expenses.
  • Retirement: Competitive retirement package to secure your future.
Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is. 

Equal Opportunity

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law".  Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.

Master's in bioinformatics or a similar field with an emphasize on analytical omics expertise. Good written and oral communication skills are required. Expertise in the use of informatics computing and data management packages. Ability to prioritize, organizes, and delegates various tasks on projects. Frequently demonstrated initiative in administration, education (seminars, training), software development, technical reports. Demonstrated success in project management and communication skills. A commitment to customer service with an attitude of owning the experience of each customer is required.


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About Mayo Clinic

Sourced by ZipRecruiter

Mayo Clinic is the largest integrated, not-for-profit medical group practice in the world. We're building the future, one where the best possible care is available to everyone — and more people can heal at home. Our relentless research turns into earlier diagnoses and new cures. That's how we inspire hope in those who need it most. At Mayo Clinic, experts work together to solve the most challenging unmet needs of patients. Our history of innovation dates back almost 150 years, when brothers Will and Charlie Mayo pioneered an integrated, team-based approach to medicine. Today, that trailblazing spirit drives innovations like Mayo Clinic Platform — which powers new technologies to change how care is delivered to all.

Industry

Hospitals

Company size

10,000+ Employees

Headquarters location

Rochester, MN, US

Year founded

1919