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Senior Automation Engineer Jobs in Missouri (NOW HIRING)

Sr. Manager, Automation Engineer

California, MO · On-site

$139.28 - $191.51/hr

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

A brief overview The Sr. Manager, Automation Engineering leads the automation engineering function supporting manufacturing, utilities, facilities, and capital projects within a regulated ...

New

Automation Engineer V

Saint Louis, MO · On-site

$101K - $132K/yr

As an Automation, Instrumentation and Controls (AIC) Engineer at CRB, you are essential to the ... The Senior Lead has a thorough understanding of the development and field implementation of ...

Automation Engineer V

Saint Louis, MO · On-site

$101K - $132K/yr

As an Automation, Instrumentation and Controls (AIC) Engineer at CRB, you are essential to the ... The Senior Lead has a thorough understanding of the development and field implementation of ...

Automation Engineer V

Saint Louis, MO · On-site

$101K - $132K/yr

As an Automation, Instrumentation and Controls (AIC) Engineer at CRB, you are essential to the ... The Senior Lead has a thorough understanding of the development and field implementation of ...

Automation QE

Saint Louis, MO · On-site

$44.75 - $59/hr

Senior Automation QE (UI) Job Location: St. Louis, MO Job Type: Contract * Develop and maintain UI ... Participate in Agile ceremonies and collaborate with developers and product owners. * Perform ...

Senior Manager, Automation Engineering - AutoGate

Noel, MO · On-site

$110K - $220K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Walmart is seeking a Senior Manager, Automation Engineering to join the Transportation Engineering team and help architect the future of one of the largest private fleets in North America. This role ...

Sr. Engineer - Digital and Automation

Saint Louis, MO · On-site

$100K - $132K/yr

  • Medical

  • Retirement

As a Senior Engineer in Digital & Automation, you'll lead digital transformation initiatives across engineering design and manufacturing operations. The ideal candidate will apply advanced controls ...

Automation Engineer Manager

California, MO · On-site

$130 - $160/hr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

Short Intro and About the Job This position will work closely with Senior Plant Leadership to direct and manage the controls and automation team. This person will be an engineering professional with ...

New

  • PTO

Our partner is looking for a Senior Automation Specialist based in Netherlands. This is a hands-on ... The role combines AI agents, reasoning systems, APIs, workflow platforms, and software engineering ...

New

Showing results 21-40

Senior Automation Engineer information

See Missouri salary details

$48.3K

$114.3K

$157.6K

How much do senior automation engineer jobs pay per year?

As of Aug 19, 2026, the average yearly pay for senior automation engineer in Missouri is $114,300.00, according to ZipRecruiter salary data. Most workers in this role earn between $97,600.00 and $128,000.00 per year, depending on experience, location, and employer.

What is a senior automation engineer?

The duties of a senior automation engineer are to develop, design, and configure systems that automate processes, such as manufacturing or software processes. Some people in this position work exclusively with software design while others work with hardware design and production. Some may provide both digital and physical solutions to automation problems. Regardless of the field, the responsibilities of a senior automation engineer are to improve efficiency while reducing the number of people it takes to complete a given process. Qualifications typically include a bachelor’s or master’s degree, experience in the industry, and leadership skills.

What are the key skills and qualifications needed to thrive as a senior automation engineer, and why are they important?

To thrive as a Senior Automation Engineer, you need a deep understanding of automation frameworks, scripting languages (such as Python or Java), and a relevant engineering degree. Familiarity with tools like Selenium, Jenkins, Docker, and CI/CD systems, along with certifications like ISTQB or Certified Automation Professional (CAP), is often required. Strong problem-solving abilities, leadership, effective communication, and collaboration skills help you excel in guiding teams and managing complex projects. These skills and qualifications are vital for ensuring the reliability, scalability, and efficiency of automated systems in fast-paced technical environments.

How does a senior automation engineer typically collaborate with cross-functional teams during large-scale projects?

Senior Automation Engineers frequently work alongside software developers, QA specialists, and operations teams to design and implement robust automated testing frameworks or process automation solutions. They often lead discussions to identify automation opportunities, define requirements, and ensure that automation integrates smoothly into existing workflows. Effective communication and documentation skills are essential, as they must translate complex technical needs for non-technical stakeholders and align efforts across departments. Collaboration may also involve mentoring junior engineers and conducting code reviews to maintain high standards and consistency.

What is the difference between Senior Automation Engineer vs Automation Engineer?

AspectSenior Automation EngineerAutomation Engineer
Required CredentialsBachelor's degree in engineering or related field; often some certifications in automation toolsBachelor's degree in engineering or related field; certifications in automation tools are common
Work EnvironmentDesigning, developing, and overseeing automation systems; leading projectsImplementing automation solutions; supporting existing systems
Employer & Industry UsageManufacturing, software, automotive, and industrial sectorsManufacturing, software development, and industrial sectors

Senior Automation Engineers typically have more experience, lead projects, and handle complex automation systems, while Automation Engineers focus on implementing and supporting automation solutions. Both roles require similar credentials and are used across various industries, but senior roles involve more leadership and strategic responsibilities.

What are the most commonly searched types of Automation Engineer jobs in Missouri?

The most popular types of Automation Engineer jobs in Missouri are:

What are popular job titles related to Senior Automation Engineer jobs in Missouri?

For Senior Automation Engineer jobs in Missouri, the most frequently searched job titles are:

What job categories do people searching Senior Automation Engineer jobs in Missouri look for?

The top searched job categories for Senior Automation Engineer jobs in Missouri are:

What cities in Missouri are hiring for Senior Automation Engineer jobs?

Cities in Missouri with the most Senior Automation Engineer job openings:

Infographic showing various Senior Automation Engineer job openings in Missouri as of August 2026, with employment types broken down into 100% Contract. Highlights an 100% In-person job distribution, with an average salary of $114,300 per year, or $55 per hour.

Senior Robotics Automation Engineer - Lab Automation Leader

Initial Therapeutics, Inc.

California, MO • On-site

$136.08 - $204.12/hr

Other

Posted 14 days ago


Job description

Job Description
Job Title:
Senior Robotics Automation Engineer
Job Requisition ID:
1752
Posting Start Date:
7/7/26

At Daiichi Sankyo, we are united by a single purpose, to improve lives around the world through innovative medicines. With a legacy of innovation since 1899, a presence in more than 30 countries, and more than 19,000 employees, we are advancing breakthrough therapies in oncology, cardiovascular disease, rare diseases, and immune disorders. Guided by our 2030 vision to "be an innovative global healthcare company contributing to the sustainable development of society", we are shaping a healthier, more hopeful future for patients, their families, and society.


Job Summary

The Senior Robotics Automation Engineer is a highly experienced technical leader responsible for advancing the design, integration, optimization, and long-term operational strategy of robotic and automated laboratory systems within the Smart Research Laboratory.

  • This role requires deep expertise in laboratory automation, engineering principles, scientific workflows, and biopharma research operations, combined with the ability to influence technical direction, guide cross-functional decision-making, and mentor less experienced engineers and scientists.
  • This individual will play a critical role in shaping automation strategy, evaluating emerging technologies, translating scientific needs into scalable automation solutions, and ensuring that robotic systems deliver reliable, precise, and high-quality performance in support of advanced drug discovery and research innovation.
  • In addition to hands-on technical execution, the Senior Robotics Automation Engineer will provide strategic guidance on system architecture, workflow design, vendor selection, platform sustainability, risk mitigation, and continuous improvement of automated laboratory capabilities.
  • The role requires regular on-site presence due to the highly integrated, hands-on nature of laboratory robotics, instrumentation, scientific equipment, and automation workcell operations.

Job Description

Responsibilities

  • Lead the design, implementation, testing, optimization, and lifecycle management of complex robotic and automated laboratory workcells, including integrated hardware, software, instrumentation, scheduling, and control systems.
  • Serve as a senior technical authority for laboratory automation platforms, providing expert guidance on system architecture, workflow design, equipment selection, integration strategy, operational scalability, and long-term platform reliability.
  • Partner with scientific, engineering, informatics, facilities, IT, and operational stakeholders to translate complex research needs into robust, scalable, and sustainable automated solutions that improve laboratory productivity, data quality, reproducibility, and research throughput.
  • Evaluate, integrate, configure, troubleshoot, and maintain advanced laboratory automation systems, including liquid handlers, dispensers, pipettors, plate movers, robotic arms, plate sealers and desealers, acoustic transfer devices, multimodal assay readers, incubators, storage systems, and related scientific instrumentation.
  • Develop, review, and optimize automation methods using orchestration and instrument-control platforms such as Momentum, Venus, InstinctS, and related automation APIs, ensuring methods are reliable, maintainable, validated, and aligned with scientific requirements.
  • Provide senior-level oversight for method development, hardware integration testing, system validation, risk assessment, troubleshooting, and performance optimization across automated laboratory workflows.
  • Lead or significantly contribute to automation roadmap planning, technology assessments, vendor evaluations, equipment acquisition decisions, and strategic recommendations that shape the future capabilities of the Smart Research Laboratory.
  • Collaborate with external vendors and internal stakeholders to implement advanced robotics capabilities, including motion planning, multi-axis actuation, control systems, autonomous mobile robotics, device communication, and integration of novel automation technologies.
  • Guide the validation, deployment, and continuous improvement of Autonomous Mobile Robot systems and other emerging automation platforms, ensuring safe, reliable, and effective operation within a research laboratory environment.
  • Mentor junior automation engineers, scientists, and cross-functional users by providing technical coaching, training, design review, troubleshooting support, and best-practice guidance for automated workflows and robotic systems.
  • Establish and maintain high-quality technical documentation, including system designs, integration plans, validation records, risk assessments, maintenance procedures, troubleshooting guides, and workflow specifications.
  • Lead complex problem-solving efforts in a fast-paced research environment, balancing immediate operational needs with long-term platform strategy, system sustainability, safety, and scientific impact.
  • Drive continuous improvement initiatives that increase automation reliability, reduce operational bottlenecks, improve assay execution quality, and expand the organization’s ability to adopt advanced automated research capabilities.

Qualifications

Education Qualifications

  • Bachelor's Degree in science, engineering, robotics, automation, computer science, life sciences or a related field required
  • Advanced degree (M.S. or Ph.D.) is preferred

Experience Qualifications

  • Requires 5-7 years of hands-on experience designing, integrating, programming, validating, maintaining, and optimizing automated laboratory equipment, robotic systems, or complex scientific instrumentation in a research or biopharma environment
  • Prior experience in biopharma, pharmaceutical, biotechnology, drug discovery, translational research, or advanced laboratory automation environment is required
  • Demonstrated ability to lead technically complex automation projects from concept through implementation, including requirements gathering, design evaluation, vendor coordination, installation, integration, testing, validation, documentation, user training, and operational handoff.
  • Advanced experience with laboratory automation platforms and orchestration software such as Hamilton Venus, Thermo Scientific Momentum, InstinctS, or comparable automation-control environments.
  • Strong working knowledge of laboratory robotics, instrument communication, scheduling systems, device APIs, mechanical and electrical integration, liquid handling principles, assay workflow automation, and system-level troubleshooting.
  • Experience developing or supporting software tools, scripts, APIs, or applications using modern programming languages such as Python, Java, C#, or comparable languages to improve automation performance, data handling, system monitoring, or workflow control.
  • Proven ability to partner with scientific teams to identify high-value automation opportunities, evaluate technical feasibility, define requirements, and deliver solutions that support research quality, throughput, reproducibility, and innovation.
  • Experience influencing technical decisions, guiding platform strategy, mentoring colleagues, and providing senior-level recommendations to scientific, operational, and leadership stakeholders.

Daiichi Sankyo, Inc. is an equal opportunity/affirmative action employer. Qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected veteran status, age, or any other characteristic protected by law.

Salary Range:

USD$136,080.00 - USD$204,120.00

Download Our Benefits Summary PDF


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