Seasonal Variant Curation Scientist Jobs (NOW HIRING)

At Caris, we understand that cancer is an ugly word—a word no one wants to hear, but one that connects us all. That’s why we’re not just transforming cancer care—we’re changing lives.We introduced precision medicine to the world and built an industry around the idea that every patient deserves answers as unique as their DNA. Backed by cutting-edge molecular science and AI, we ask ourselves every day: “What would I do if this patient were my mom?” That question drives everything we do.But our mission doesn’t stop with cancer. We're pushing the frontiers of medicine and leading a revolution in healthcare—driven by innovation, compassion, and purpose.Join us in our mission to improve the human condition across multiple diseases. If you're passionate about meaningful work and want to be part of something bigger than yourself, Caris is where your impact begins.Position SummaryThe Curation Scientist, Biomarker & Drug Intelligence – Precision Oncology or Hematology, is a key member of the Biomarker & Drug Intelligence team and supports the development, maintenance, and continuous improvement of the knowledgebase that powers Caris Molecular Intelligence and other Caris products. This role identifies, evaluates, synthesizes, and documents scientific and clinical evidence related to oncology and hematology biomarkers, molecular alterations, tumor biology, and therapeutic relevance in precision oncology.Job ResponsibilitiesMonitor emerging scientific, medical, and clinical literature, clinical guidelines, and public databases relevant to oncology and hematology biomarkers and therapies.Evaluate and curate evidence related to cancer biology, molecular oncology, targeted therapy, immuno-oncology, hereditary cancer risk, hematologic malignancies, and related disease areas.Develop clear, structured documentation to support knowledgebase updates, biomarker interpretations, report content, and therapeutic associations.Translate complex scientific findings into actionable content for clinical, product, and operational use.Collaborate with cross-functional teams to review proposed changes and ensure evidence interpretation aligns with product requirements.Present scientific findings and evidence-based recommendations to internal stakeholders.Support quality assurance and implementation activities to ensure approved updates are accurately reflected across products and workflows.Contribute to process improvement initiatives, training materials, scientific summaries, presentations, and other special projects as needed.Required QualificationsPh.D. in oncology, cancer biology, molecular biology, genetics, genomics, hematology, pharmacology, or a related scientific discipline, or a Master’s degree with relevant experience.Minimum of 3–5 years of experience in literature curation, scientific evidence assessment, or scientific review within molecular diagnostics, oncology, hematology, biotechnology, pharmaceutical, or healthcare environments.Demonstrated ability to critically evaluate scientific and clinical literature and assess evidence strength and relevance.Strong written and verbal communication skills with the ability to clearly summarize complex scientific information.Excellent attention to detail, organization, and documentation skills.Ability to manage multiple priorities and work effectively in a fast-paced, cross-functional environment.Proficiency with scientific and clinical resources including PubMed, NCCN guidelines, ClinVar, COSMIC, OncoKB, CIViC, and ClinicalTrials.gov.Proficient in Microsoft Office Suite, including Word, Excel, Outlook, and general working knowledge of internet-based business tools.Preferred QualificationsExperience in precision oncology, molecular diagnostics, oncology biomarker interpretation, or hematologic malignancies.Familiarity with somatic and germline variant interpretation, clinical guidelines, and evidence grading frameworks.Experience supporting knowledgebase curation, clinical content development, or rules-based implementation workflows.Physical DemandsPrimarily sedentary work involving prolonged periods of sitting. Occasional standing, walking, and use of standard office equipment such as computers and telephones. Ability to communicate effectively and review detailed scientific and clinical documentation.TrainingAll job-specific, safety, and compliance training are assigned based on the job functions associated with this position.OtherThis position may require occasional evenings, weekends, or additional hours to meet business needs or project deadlines.Conditions of Employment: Individual must successfully complete pre-employment process, which includes criminal background check, drug screening, credit check ( applicable for certain positions) and reference verification.This job description reflects management’s assignment of essential functions. Nothing in this job description restricts management’s right to assign or reassign duties and responsibilities to this job at any time.Caris Life Sciences is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, gender, gender identity, sexual orientation, age, status as a protected veteran, among other things, or status as a qualified individual with disability. #J-18808-Ljbffr