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Jazz Pharmaceuticalsis a global biopharma company whose purpose is to innovate to transform the lives of patients and their families. We are dedicated to developing life-changing medicines for people with serious diseases - often with limited or no therapeutic options. We have a diverse portfolio of marketed medicines, including leading therapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments. Our patient-focused and science-driven approach powers pioneering research and development advancements across our robust pipeline of innovative therapeutics in oncology and neuroscience. Jazz is headquartered inDublin, Irelandwith research and development laboratories, manufacturing facilities and employees in multiple countries committed to serving patients worldwide. Please visitwww.jazzpharmaceuticals.comfor more information.

The Senior Manager of Real-World Evidence (RWE) will lead or provide (scientific/strategic/tactical/etc) support on RWE studies and analyses using administrative claims data/EMR, reporting to the Head of RWE. The Senior Manager of RWE will function on an analytics team responsible for establishing rigorous assessments of administrative claims data/EMR to evaluate real-world outcomes for all Jazz products. The incumbent will provide leadership or support for projects under his/her direct responsibility and oversee the tactical planning and execution of RWE projects conducted by RWE analytic team or external vendors. The candidate will also ensure the timeliness and delivery of scientifically valid research.

Essential Functions/Responsibilities

Lead the design and execution of RWE research projects using administrative claims data/ EMR, including the development of protocols and contributions to statistical analysis plans (SAPs).

Support the development of RWE strategies for one or multiple molecules, in collaboration with internal partners, to ensure that the value of Jazz products is fully supported by evidence for global and regional audiences.

Drive RWE innovations and effective communication with internal stakeholders, regulatory bodies, health technology assessment bodies, and scientific communities; continuously strive to publish results in peer-reviewed journals and conferences.

Leverage advanced communication and translation skills and strategic planning across health economics and outcomes research, medical affairs, and clinical development functions.

Support the Evidence & Value Generation (EVG) department in developing and implementing operational processes related to daily RWE activities for internal departments.

Assess real-world data assets and establish data curation plans, including provisioning data licenses and platforms, in collaboration with the EVG leadership team.

Stay current with research on RWE methodology and its applications as pertinent to project needs.

Familiarity with the US and global health care delivery system (e.g., payers and reimbursement models)

Experience in designing, collecting, and analyzing RWD/RWE using administrative claims datasets, EMRs, and patient charts

Strong analytical skills and ability to work with multi-disciplinary teams required to support program, project, and contract management and financial reporting

Experience with big data analytical platforms

A track record of peer-reviewed scientific publications demonstrating expertise in RWE

Demonstrated strategic and conceptual skills to develop innovative approaches for developing product differentiation

PhD in epidemiology or related discipline with 3+ years of research experience or MS in epidemiology with 5+ years research experience

At least 2 years with analytic experience of healthcare claims databases/EMR within the biopharmaceutical industry or provider/payer organizations

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Jazz Pharmaceuticals is an equal opportunity/affirmative action employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any characteristic protected by law.

FOR US BASED CANDIDATES ONLY

Jazz Pharmaceuticals, Inc. is committed to fair and equitable compensation practices and we strive to provide employees with total compensation packages that are market competitive.For this role, the full and complete base pay range is:

Individual compensation paid within this range will depend on many factors, including qualifications, skills, relevant experience, job knowledge, and other pertinent factors. The goal is to ensure fair and competitive compensation aligned with the candidate's expertise and contributions, within the established pay framework and our Total Compensation philosophy. Internal equity considerations will also influence individual base pay decisions. This range will be reviewed on a regular basis.

At Jazz, your base pay is only one part of your total compensation package. The successful candidate may also be eligible for a discretionary annual cash bonus or incentive compensation (depending on the role), in accordance with the terms of the Company's Global Cash Bonus Plan or Incentive Compensation Plan, as well as discretionary equity grants in accordance with Jazz's Long Term Equity Incentive Plan.

The successful candidate will also be eligible to participate in various benefits offerings, including, but not limited to, medical, dental and vision insurance, 401k retirement savings plan, and flexible paid vacation.For more information on our Benefits offerings please click here: https://careers.jazzpharma.com/benefits.html