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What is a liquid biopsy genomics specialist?

A Liquid Biopsy Genomics specialist is a professional who analyzes genetic material from blood or other body fluids to detect, monitor, and study diseases like cancer. They utilize advanced genomic techniques to identify circulating tumor DNA (ctDNA), RNA, or other biomarkers, often helping guide treatment decisions and track disease progression non-invasively. This role combines expertise in molecular biology, bioinformatics, and clinical diagnostics to interpret complex genomic data and improve patient outcomes.

What are the key skills and qualifications needed to thrive as a liquid biopsy genomics specialist?

To thrive as a Liquid Biopsy Genomics Specialist, you need a strong background in molecular biology, next-generation sequencing (NGS), and oncology, typically supported by an advanced degree in life sciences. Familiarity with bioinformatics tools, laboratory automation systems, and experience with platforms such as Illumina or Thermo Fisher are commonly required. Attention to detail, problem-solving ability, and excellent communication skills help professionals interpret complex data and collaborate with multidisciplinary teams. These skills ensure accurate analysis and reporting of genomic data, which are critical for guiding personalized cancer treatment decisions.

What are some common challenges faced by professionals working in liquid biopsy genomics, and how can they be addressed?

Professionals in Liquid Biopsy Genomics often encounter challenges such as handling highly sensitive assays, interpreting complex genomic data, and ensuring rigorous sample quality control. Working closely with multidisciplinary teams—including bioinformaticians, clinicians, and laboratory staff—is essential for accurate data analysis and clinical interpretation. Staying updated with evolving technologies and regulatory guidelines helps address these challenges, as does participating in ongoing training and open communication within the team.

What is the difference between Liquid Biopsy Genomics vs Molecular Laboratory Technician?

AspectLiquid Biopsy GenomicsMolecular Laboratory Technician
Required CredentialsMaster's or PhD in genomics, molecular biology, or related fieldAssociate's or Bachelor's degree in laboratory sciences or related field
Work EnvironmentResearch labs, biotech companies, hospitalsClinical laboratories, research facilities, hospitals
Industry UsageGenomics, cancer diagnostics, personalized medicineClinical testing, sample processing, assay preparation
Common Search/ComparisonYesNo

Liquid Biopsy Genomics specialists focus on analyzing circulating tumor DNA for cancer detection, requiring advanced degrees and research skills. Molecular Laboratory Technicians perform routine sample processing and testing in clinical labs, often with an associate's or bachelor's degree. While both roles work in laboratory settings, Liquid Biopsy Genomics involves more research and data analysis, whereas Molecular Laboratory Technicians handle day-to-day testing procedures.

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Liquid Biopsy Genomics jobs near you
Infographic showing various Liquid Biopsy Genomics job openings in the United States as of August 2026, with employment types broken down into 2% As Needed, 81% Full Time, 14% Part Time, 2% Contract, and 1% Nights. Highlights an 96% Physical, 1% Hybrid, and 3% Remote job distribution.

Senior Bioinformatics Scientist, Translational Bioinformatics

Predicine, Inc

Hayward, CA • On-site

Full-time

Posted 15 days ago

Job description

Location: Hayward, CA
Work Arrangement: TBD
Department: Translational Bioinformatics (NGS/Liquid Biopsy)
Employment Type: Full-TimeAbout Predicine

Predicine is a precision oncology company advancing the fight against cancer through cutting-edge genomic technologies and liquid biopsy solutions. We partner with pharmaceutical companies, clinicians, and researchers worldwide to bring next-generation diagnostics from bench to bedside — faster, smarter, and more accessible. Join a team where your work directly impacts patient outcomes and the future of cancer care.

Job Summary

We are seeking a highly motivated senior bioinformatics scientist to support NGS-based liquid biopsy studies and translational bioinformatics programs. The incumbent will analyze cfDNA/cfRNA, tissue, RNA-seq, multi-omics, and clinical data to develop biomarker testing strategies for cancer diagnosis and clinical applications. This is a client-facing scientist role — you'll represent the scientific team in technology meetings with pharmaceutical clients, KOLs, and client data scientists, translating client needs into analysis plans, result interpretation, and follow-up support with a client-success mindset. This is an exciting opportunity to join a fast-growing startup, accelerate your growth, and make a positive, immediate impact on cancer diagnosis and treatment.

What You'll Do

The Senior Bioinformatics Scientist, NGS and Liquid Biopsy will lead bioinformatics analysis in support of NGS-based liquid biopsy studies and translational bioinformatics programs. This role will analyze cfDNA/cfRNA, tumor tissue, RNA-seq, multi-omics, and clinical datasets to develop and refine biomarker testing strategies for cancer diagnosis and clinical applications. Serving as a client-facing scientific partner, the incumbent will represent the scientific team in technology meetings with pharmaceutical clients, KOLs, and client data scientists — translating client needs into analysis plans, interpreting results, and providing ongoing follow-up support with a client-success mindset. The position will also develop and improve computational pipelines, statistical models, and machine-learning approaches for sequencing QC, variant analysis, and study-specific analyses, while coordinating internal and external collaborations, scientific presentations, publications, and mentoring across translational bioinformatics projects.

Key Responsibilities & Time Allocation % of TimeResponsibility35%Bioinformatics Analysis Leadership — Lead bioinformatics analysis for NGS and liquid biopsy studies, including assay development, validation support, interpretation, and biomarker reporting.25%Multi-Omics Data Analysis — Analyze clinical, genomic, transcriptomic, proteomic, and other multi-omics datasets to identify biomarkers, targets, and tumor biology insights.20%Pipeline & Model Development — Develop and improve computational pipelines, statistical models, and machine-learning approaches for sequencing QC, variant analysis, annotation, and study-specific analyses.15%Client-Facing Scientific Partnership — Serve as a client-facing scientific partner in technology meetings, aligning scope, data interpretation, deliverables, and follow-up with clients and KOLs.5%Collaboration & Mentorship — Coordinate internal/external collaborations, scientific presentations, publications, and mentoring for translational bioinformatics projects.


What You Bring

Education


MinimumPreferredLevelMaster's degree with 5+ years of relevant experienceDoctorate (PhD)Field of StudyBioinformatics, Computational Biology, Biostatistics, Genomics, Molecular Biology, Cancer Biology, or related fieldSame fields


Experience


MinimumPreferredWork Experience3+ years post-graduation with hands-on NGS analysis and client-facing collaboration experiencePharmaceutical industry experience; tumor research publications or experience


Required Skills & Qualifications

  • Strong R and/or Python programming skills; familiarity with Unix/Linux and reproducible workflows
  • Hands-on NGS and liquid biopsy analysis experience, including cfDNA/cfRNA, tumor tissue, RNA-seq, or single-cell data
  • Experience with variant analysis, CNV/fusion analysis, MSI/TMB, multi-omics integration, statistics, or machine learning
  • Strong publication or meeting presentation record, with clear scientific writing skills
  • Excellent client-facing communication with pharma clients, KOLs, client data scientists, and internal cross-functional teams

Preferred Skills & Qualifications

  • Pharmaceutical industry experience
  • Tumor research publications or hands-on tumor research experience
Join Us
At Predicine, you won't just analyze data — you'll help translate cutting-edge genomic science into real diagnostic tools that change how cancer is detected and treated. If you're a scientist who thrives at the intersection of deep technical analysis and client partnership, we want to hear from you.

Apply today and help us turn breakthrough science into better patient outcomes.

Predicine is an Equal Opportunity Employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.