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Crispr Therapeutics Jobs (NOW HIRING)

Crispr Therapeutics

Scientist II, LNP

South Boston, MA · On-site

$130K - $140K/yr

CRISPR Therapeutics is advancing a broad and diversified pipeline across hemoglobinopathies, cardiovascular, autoimmune, oncology, regenerative medicine and rare diseases. The Company continues to ...

Crispr Therapeutics

Director, LNP Discovery

Boston, MA

$195K - $215K/yr

CRISPR Therapeutics AGis headquartered inZug, Switzerland, with its wholly-ownedU.S.subsidiary,CRISPR Therapeutics, Inc., and R&D operations based inBoston, MassachusettsandSan Francisco, California.

Crispr Therapeutics

Scientist II, LNP

Boston, MA

$130K - $140K/yr

CRISPR Therapeutics AGis headquartered inZug,Switzerland, with its wholly-ownedU.S.subsidiary,CRISPR Therapeutics, Inc., and R&D operations based inBoston, MassachusettsandSan Francisco,California.

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How much do crispr therapeutics jobs pay per hour?

As of Jul 30, 2026, the average hourly pay for crispr therapeutics in the United States is $31.48, according to ZipRecruiter salary data. Most workers in this role earn between $19.23 and $40.14 per hour, depending on experience, location, and employer.

What careers work with CRISPR?

Careers that work with CRISPR include molecular biologists, geneticists, bioinformatics specialists, and laboratory technicians. These roles involve designing, testing, and applying gene-editing techniques, often requiring knowledge of genetics, laboratory skills, and familiarity with CRISPR tools and protocols.

What is a Crispr Therapeutics job?

A CRISPR Therapeutics job typically involves working with gene-editing technologies to develop treatments for genetic diseases. Employees may work in research, development, clinical trials, or regulatory roles to advance CRISPR-based therapies. Positions range from scientists and bioengineers to project managers and regulatory specialists. The goal is to translate CRISPR technology into real-world medical applications.

What are the key skills and qualifications needed to thrive in the Crispr Therapeutics position, and why are they important?

To excel in CRISPR Therapeutics roles, candidates typically need a solid background in molecular biology, genetics, or biotechnology, along with a relevant advanced degree (e.g., Ph.D., M.Sc., or B.Sc. with experience). Familiarity with genome editing technologies such as CRISPR-Cas9, cell culture systems, PCR, and next-generation sequencing is crucial, and certifications in laboratory safety or bioinformatics can be valuable. Strong analytical thinking, problem-solving, attention to detail, and the ability to collaborate within multidisciplinary research teams set top performers apart. These skills and qualities are vital for ensuring rigorous scientific research, innovation, and effective teamwork in a rapidly evolving biotech environment.

Does CRISPR Therapeutics have a future?

CRISPR Therapeutics is a leading company in gene editing technology, with ongoing research and development in therapies for genetic diseases. The company's focus on innovative CRISPR-based treatments suggests a strong potential for growth and impact in the biotech industry. Job roles within the company often require knowledge of molecular biology and gene editing tools, indicating a future-oriented environment for professionals in the field.

What does the typical day-to-day work look like in a CRISPR Therapeutics position?

In a CRISPR Therapeutics role, your day-to-day tasks often include designing and conducting experiments, analyzing genomic data, and troubleshooting laboratory protocols related to gene editing projects. You’ll work closely with scientists across functional teams, such as protein engineers, bioinformaticians, and clinical researchers, to advance therapeutic candidates from discovery through preclinical stages. Regular meetings to discuss results and plan next steps are common, and documentation of experiments and findings is crucial for regulatory compliance. Staying up to date with the latest scientific literature and adapting to new techniques is also an ongoing part of the job.

How much does CRISPR pay?

Salaries for CRISPR-related roles, such as research scientists or biotech engineers, typically range from $70,000 to over $130,000 annually, depending on experience, education, and location. Entry-level positions may start lower, while senior roles or specialized positions can offer higher compensation, often with benefits and bonuses included.

Is CRISPR a good company to work for?

CRISPR Therapeutics is a biotechnology company focused on gene editing therapies, offering roles that involve scientific research, laboratory work, and collaboration in a biotech environment. Employee experiences vary, but the company is known for its innovative work in CRISPR technology and competitive benefits. Job seekers should consider their interest in biotech and gene editing when evaluating opportunities there.
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Crispr Therapeutics jobs near you
Infographic showing various Crispr Therapeutics job openings in the United States as of July 2026, with employment types broken down into 8% As Needed, 60% Full Time, 28% Part Time, 1% Temporary, 2% Contract, and 1% Nights. Highlights an 67% Physical, 1% Hybrid, and 32% Remote job distribution, with an average salary of $65,473 per year, or $31.5 per hour.

Research Associate II, CRISPR-X - LNP

Crispr Therapeutics

South Boston, MA • On-site

Full-time

Re-posted 9 days ago

Job description

Job Description:
Company Overview
Founded over a decade ago, CRISPR Therapeutics is a leading biopharmaceutical company focused on developing transformative gene-based medicines for serious human diseases. The Company has evolved from a pioneering research-stage organization into an industry leader, marking a historic milestone with the approval of CASGEVY® (exagamglogene autotemcel [exa-cel]), the world's first CRISPR-based therapy, approved for eligible patients with sickle cell disease and transfusion-dependent beta thalassemia. CRISPR Therapeutics is advancing a broad and diversified pipeline across hemoglobinopathies, cardiovascular, autoimmune, oncology, regenerative medicine and rare diseases. The Company continues to expand its leadership in gene editing through the development of SyNTase™ editing, a novel and proprietary gene-editing platform designed to enable precise, efficient, and scalable gene correction. To accelerate and expand its impact, CRISPR Therapeutics has established strategic collaborations with leading biopharmaceutical partners, including Vertex Pharmaceuticals. CRISPR Therapeutics AG is headquartered in Zug, Switzerland, with its wholly-owned U.S. subsidiary, CRISPR Therapeutics, Inc., and R&D operations based in Boston, Massachusetts and San Francisco, California.
Position Summary
We are seeking a highly motivated Research Associate II to support the design, development, and optimization of novel lipid nanoparticle (LNP) formulations to advance our non-viral delivery platform for hepatic and extra-hepatic tissues, and enable next-generation genome editing therapies from discovery through clinical translation.
The ideal candidate will bring hands-on expertise in LNP formulation development, scale-up, analytical characterization, chemistry, and process development, with a strong passion for innovation in nucleic acid delivery technologies. This individual will join the dynamic, fast-growing, and highly collaborative CRISPR-X division and contribute to both platform technology innovation and preclinical therapeutic programs.
In this role, the candidate will work cross-functionally to develop and characterize advanced delivery systems for emerging editing modalities, helping drive transformative gene editing therapies toward patients with unmet medical needs.
Responsibilities
  • Design, optimize, characterize, and execute lipid nanoparticle (LNP) formulations across a diverse range of lipid compositions and therapeutic payloads with minimal supervision.
  • Apply hands-on expertise in LNP analytical characterization techniques, including RiboGreen assays, DLS, NanoFCM, NTA, TFF, endotoxin testing, and HPLC, as well as molecular biology methods such as DNA/RNA extraction, ELISA, SDS-PAGE, PCR, and Western blotting.
  • Generate high-quality, reproducible datasets and maintain accurate, detailed experimental documentation in electronic laboratory notebooks (ELNs).
  • Perform mammalian cell culture and support in vitro studies, including transient transfection and electroporation in established cell lines. Collaborate cross-functionally with process development, analytical, and in vivo teams to support reproducible manufacturing processes and advance programs toward clinical development.
  • Contribute to platform innovation by investigating LNP mechanisms of action to improve delivery efficiency, therapeutic potency, and formulation stability.
  • Present experimental results, technical findings, and project updates to cross-functional teams and broader organizational audiences.
  • Effectively manage multiple priorities and projects in a fast-paced, highly collaborative research environment.

Minimum Qualifications
  • BS or MS in Chemistry, Chemical Engineering, Biochemistry, or a related scientific discipline.
  • Relevant industry or academic research experience:
    • Research Associate II: 2-5+ years with a bachelor's degree or 0-2+ years of relevant experience with a master's degree
  • Hands-on experience in lipid nanoparticle (LNP) formulation and analytical characterization for nucleic acid and targeted delivery applications.
  • Strong understanding of drug delivery systems and gene editing therapeutics.
  • Demonstrated ability to work independently while contributing effectively within a fast-paced, results-driven, and collaborative research environment.
  • Highly organized with strong scientific rigor, problem-solving skills, and attention to detail.

Preferred Qualifications
  • Experience with high-throughput formulation screening and knowledge of microfluidic mixing process.
  • Prior experience of ionizable lipid design, bioconjugation, and process development preferred.
  • Prior experience with scale-up and large-scale manufacturability development of LNPs.
  • Understanding of RNA engineering, molecular biology, and hands-on experience of maintaining cells and performing in vitro transfection.

Competencies
  • Collaborative - Openness, One Team
  • Undaunted - Fearless, Can-do attitude
  • Results Orientation - Delivering progress toward our mission. Sense of urgency in solving problems.
  • Entrepreneurial Spirit - Proactive. Ownership mindset.

Due to the nature of their work, our manufacturing and lab-based positions are located fully on-site.
Research Associate II: Base pay range of $85,000 to $92,000 + discretionary bonus, equity and benefits.
The range provided is CRISPR Therapeutics' reasonable estimate of the base compensation for this role. The actual amount will be based on job-related and non-discriminatory factors such as experience, training, skills, and abilities.
CRISPR Therapeutics, Inc. is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law.
To view our Privacy Statement, please click the following link: http://www.crisprtx.com/about-us/privacy-policy

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