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Crispr Therapeutics Jobs (NOW HIRING)

Scientist II, LNP

Boston, MA · On-site

$130K - $140K/yr

CRISPR Therapeutics AGis headquartered inZug,Switzerland, with its wholly-ownedU.S.subsidiary,CRISPR Therapeutics, Inc., and R&D operations based inBoston, MassachusettsandSan Francisco,California.

Clinical Trial Associate

South Boston, MA · On-site

$36.50 - $49.75/hr

CRISPR Therapeutics is advancing a broad and diversified pipeline across hemoglobinopathies, cardiovascular, autoimmune, oncology, regenerative medicine and rare diseases. The Company continues to ...

$140 - $155/hr

CRISPR Therapeutics is advancing a broad and diversified pipeline across hemoglobinopathies, cardiovascular, autoimmune, oncology, regenerative medicine and rare diseases. The Company continues to ...

$105 - $115/hr

Founded over a decade ago, CRISPR Therapeutics is a leading biopharmaceutical company focused on developing transformative gene-based medicines for serious human diseases. The Company has evolved ...

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How much do crispr therapeutics jobs pay per hour?

As of Sep 2, 2026, the average hourly pay for crispr therapeutics in the United States is $31.48, according to ZipRecruiter salary data. Most workers in this role earn between $19.23 and $40.14 per hour, depending on experience, location, and employer.

What is a Crispr Therapeutics?

A CRISPR Therapeutics job typically involves working with gene-editing technologies to develop treatments for genetic diseases. Employees may work in research, development, clinical trials, or regulatory roles to advance CRISPR-based therapies. Positions range from scientists and bioengineers to project managers and regulatory specialists. The goal is to translate CRISPR technology into real-world medical applications.

What does a Crispr Therapeutics do?

In a CRISPR Therapeutics role, your day-to-day tasks often include designing and conducting experiments, analyzing genomic data, and troubleshooting laboratory protocols related to gene editing projects. You’ll work closely with scientists across functional teams, such as protein engineers, bioinformaticians, and clinical researchers, to advance therapeutic candidates from discovery through preclinical stages. Regular meetings to discuss results and plan next steps are common, and documentation of experiments and findings is crucial for regulatory compliance. Staying up to date with the latest scientific literature and adapting to new techniques is also an ongoing part of the job.

What are the key skills and qualifications needed to thrive in a Crispr Therapeutics position?

To excel in CRISPR Therapeutics roles, candidates typically need a solid background in molecular biology, genetics, or biotechnology, along with a relevant advanced degree (e.g., Ph.D., M.Sc., or B.Sc. with experience). Familiarity with genome editing technologies such as CRISPR-Cas9, cell culture systems, PCR, and next-generation sequencing is crucial, and certifications in laboratory safety or bioinformatics can be valuable. Strong analytical thinking, problem-solving, attention to detail, and the ability to collaborate within multidisciplinary research teams set top performers apart. These skills and qualities are vital for ensuring rigorous scientific research, innovation, and effective teamwork in a rapidly evolving biotech environment.

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Infographic showing various Crispr Therapeutics job openings in the United States as of August 2026, with employment types broken down into 2% As Needed, 93% Full Time, 3% Part Time, and 2% Contract. Highlights an 82% Physical, 3% Hybrid, and 15% Remote job distribution, with an average salary of $65,473 per year, or $31.5 per hour.

Scientist II, in vivo Gene Insertion

Crispr Therapeutics

San Francisco, CA • On-site

$130/hr

Full-time

Re-posted 9 days ago


Job description

Job Description:
Company Overview
Founded over a decade ago, CRISPR Therapeutics is a leading biopharmaceutical company focused on developing transformative gene-based medicines for serious human diseases. The Company has evolved from a pioneering research-stage organization into an industry leader, marking a historic milestone with the approval of CASGEVY® (exagamglogene autotemcel [exa-cel]), the world's first CRISPR-based therapy, approved for eligible patients with sickle cell disease and transfusion-dependent beta thalassemia. CRISPR Therapeutics is advancing a broad and diversified pipeline across hemoglobinopathies, cardiovascular, autoimmune, oncology, regenerative medicine and rare diseases. The Company continues to expand its leadership in gene editing through the development of SyNTase™ editing, a novel and proprietary gene-editing platform designed to enable precise, efficient, and scalable gene correction. To accelerate and expand its impact, CRISPR Therapeutics has established strategic collaborations with leading biopharmaceutical partners, including Vertex Pharmaceuticals. CRISPR Therapeutics AG is headquartered in Zug, Switzerland, with its wholly-owned U.S. subsidiary, CRISPR Therapeutics, Inc., and R&D operations based in Boston, Massachusetts and San Francisco, California.
Position Summary
We are seeking highly motivated, talented, and independent researchers to grow our diverse, innovation-focused CRISPR-X team that pioneers novel in-vivo gene editing therapies for human disease. As part of CRISPR Therapeutics, a leading gene editing company, the candidate will be focused on working with our team on developing and enabling in vivo gene insertion across multiple tissue and cell types, with the goal of advancing cutting-edge in-vivo gene editing modalities across a range of different disease indications. The successful candidate will be comfortable working with different gene editing systems, possess a strong immunology and/or synthetic immunology background, and is comfortable moving into new areas of biology as needed. The position requires enthusiasm, adaptability, attention to detail, and a desire to create new medicines for patients.
Responsibilities
  • Design and execute workflows of conceive, build, and assess in primary cells
    • Requires extensive hands-on knowledge of molecular biology strategies, including advanced cloning methods, experience in handling various primary cell types (including T cells), familiarity with delivery strategies from transfection to viral transduction to novel targeted LNP (tLNP) approaches.
    • Strong sense of teamwork. Collaborate with various groups within CRISPR Tx and outside vendors to advance projects from both an editing and delivery perspective, with the ultimate goal of clinical readiness.
    • Extensive experience in quantitative biology. Iterate on assessing editing efficiency/gene insertion, impact on cell phenotype/construct expression, and ideation of new strategies.
  • Design and execute ddPCR assays to quantify transgene integration efficiency
  • Design and execute T cell phenotyping assays such as multicolor flow cytometry panels
  • Leverage immunology and/or synthetic immunology background to drive innovative editing, delivery, and expression strategies
  • Work cross-functionally to assess editing outcomes in animal models
  • Analyze and present experimental data to a wide range of audiences
  • Generate, manage, evaluate, and maintain critical data in a highly organized manner, providing statistical analysis and troubleshooting where appropriate

Minimum Qualifications
  • Extensive prior experience with gene editing and synthetic immunology in an academic and/or industry setting, with a track record demonstrating significant contributions.
  • Depending on level, degrees in Biology, Immunology, Genetics, Bioengineering, or related disciplines (level commensurate with experience and achievement):
    • Scientist II - PhD with minimum of 2-5+ years relevant experience; non-PhD with 10-12+ years progressive, relevant experience
  • Excellent technical skills for cloning, flow cytometry, primary T cell culturing, editing assays, and assessment of T cell phenotype and function
  • Experience managing multiple projects and priorities; ability to jump in to help other projects as needed
  • Strong communicator with a demonstrated record of being a highly collaborative team player within and across multiple departments

Preferred Qualifications
  • Knowledge and experience with in vivo delivery modalities such as tLNP, AAV, VLP, and others
  • Knowledge and experience with developing novel editing modalities

Competencies
  • Collaborative - Openness, One Team
  • Undaunted - Fearless, Can-do attitude
  • Results Orientation - Delivering progress toward our mission. Sense of urgency in solving problems.
  • Entrepreneurial Spirit - Proactive. Ownership mindset.

Due to the nature of their work, our manufacturing and lab-based positions are located fully on-site.
Scientist II: Base pay range of $130,000 to $140,000+ bonus, equity and benefits
The range provided is CRISPR Therapeutics' reasonable estimate of the base compensation for this role. The actual amount will be based on job-related and non-discriminatory factors such as experience, training, skills, and abilities.
Pursuant to the San Francisco Fair Chance Ordinance, we will consider for employment qualified applicants with arrest and conviction records.
CRISPR Therapeutics, Inc. is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law.
To view our Privacy Statement, please click the following link: http://www.crisprtx.com/about-us/privacy-policy