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Director Preclinical Jobs (NOW HIRING)

Touro University

Preclinical Faculty

Hawthorne, NY

$56K - $70K/yr

This position directly reports to their Course Director at the Touro College of Dental Medicine and indirectly to the Director of Preclinical Education, Preclinical Faculty. * Attend all lectures and ...

North American Science Associates, Inc.

North American Science Associates, Inc. is looking for a qualified Associate to assist in coordinating study conduct tasks from initiation to completion. The role involves interacting with clients ...

CEDENT

Director of Preclinical Research

Durham, NC · On-site +1

With the goal of further increasing the pace of progress towards better treatments, we're hiring a Director of Preclinical Research to help us pursue a growing number of research opportunities ...

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Director Preclinical information

What are the key skills and qualifications needed to thrive in the Director Preclinical position, and why are they important?

To thrive as a Director Preclinical, you need in-depth expertise in drug development, toxicology, and pharmacology, typically supported by an advanced degree (PhD, PharmD, or DVM) and significant industry experience. Familiarity with preclinical study design, regulatory submission platforms (such as IND/CTA), and relevant quality management systems is vital. Strong leadership, strategic planning, and communication skills make candidates stand out for effectively managing multidisciplinary teams and partnerships. These competencies are critical for ensuring timely progress of drug candidates through preclinical stages while maintaining compliance and scientific rigor.

What are the typical responsibilities and team dynamics for a Director Preclinical?

As a Director Preclinical, you will oversee the planning, execution, and interpretation of preclinical research studies supporting drug discovery and development. This leadership role often involves managing cross-functional teams of scientists, project managers, and external partners such as contract research organizations (CROs). You will regularly collaborate with colleagues in regulatory affairs, clinical development, and senior management to align research objectives with overall company goals. The work environment is both strategic and hands-on, requiring frequent communication and the ability to facilitate problem-solving across departments. This role is ideal for professionals who enjoy leading scientific innovation while navigating the complex regulatory landscape of new drug development.

What does a Director Preclinical do?

A Director of Preclinical research oversees the early-stage development of drugs, medical devices, or therapies before human clinical trials begin. They manage preclinical studies, ensuring regulatory compliance, scientific rigor, and alignment with company goals. Responsibilities include designing research strategies, supervising laboratory teams, interpreting data, and collaborating with regulatory agencies such as the FDA. Their role is critical in assessing the safety and effectiveness of new treatments before advancing to human trials.

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Director Preclinical jobs near you
Director/Senior Director, Preclinical Program Leadership

Director/Senior Director, Preclinical Program Leadership

EVOZYNE INC

Chicago, IL • On-site

$175K - $250K/yr

Full-time

Re-posted 22 days ago

Job description

Evozyne is an AI-native biotech company building a new way to design therapeutic proteins. Our generative AI platform was purpose-built to create entirely novel proteins that expand what’s possible beyond traditional drug discovery. We are applying this platform to develop transformative therapies for serious diseases with significant unmet need, working at the intersection of AI, biology, and protein engineering to solve complex scientific problems that conventional approaches cannot easily address.

As the Director/Senior Director, Preclinical Program Leadership, you will own the operations and execution of advancing therapeutic assets from candidate nomination through IND submission across multiple programs. You will play a central role in efficiently moving programs toward the clinic while helping shape how program leadership operates and scales within the company.

Reporting to the Chief Operating Officer, you will bring deep experience in preclinical program leadership, IND enablement, strong strategic and operational judgment, and clear communication to ensure programs progress effectively across complex, interdependent workstreams.

Location: Remote

What You’ll Do

  • Own program execution and operations from candidate nomination through IND clearance and Phase 1 enablement across multiple assets in parallel
  • Drive the critical path, including timelines, budgets, dependencies, and decision points
  • Build and maintain integrated development plans spanning workstreams across multple functional areas
  • Translate program progress into clear, actionable updates and recommendations for leadership
  • Own external partnerships with CROs and CDMOs, including vendor selection, scope definition, and ongoing performance management
  • Negotiate scope, cost, timelines, and deliverables, and hold partners accountable to outcomes
  • Coordinate across multiple vendors simultaneously, managing handoffs, data flow, and interdependencies
  • Partner with internal technical experts to design studies and translate program needs into effective external workstreams
  • Oversee development of study protocols, incorporating cross-functional input and aligning stakeholders
  • Build the internal playbooks, processes, and operating structures needed to scale program execution across the pipeline

Who You Are

You are the central operator in all aspects of advancing IND programs, bringing in internal stakeholders, external consultants, and technical partners as needed. You thrive in a dynamic environment where you’re balancing speed, cost, and risk to ensure successful IND submissions. You think big on high-level regulatory and technical strategy while maintaining the attention to detail required to plan multiple steps ahead. You have a strong ownership mentality acting as the operational leader for our preclinical programs.

Required Experience

  • Direct operational ownership of multiple IND programs in biologics, with at least one specifically in functional protein therapeutics
  • Advanced degree in biochemical, pharmacology, toxicology or related field such as biology and life sciences
  • 8+ years (Ph.D.) to 12+ years (Master’s) of relevant industry experience
  • Demonstrated success leading programs through CROs and CDMOs, including global vendors.
  • Deep understanding of the drug development process from discovery through IND filing
  • Strong familiarity with GxP, ICH guidelines, and FDA preclinical requirements
  • Proven ability to align and influence stakeholders across functions and organizations

What We’re Looking For

  • Strong strategic and operational judgment
  • Clear, concise communicator who can simplify complex programs
  • Highly organized and detail-oriented, with the ability to anticipate challenges
  • Hands-on leader who is comfortable owning outcomes directly
  • Effective at influencing without formal authority
  • Comfortable operating in a fast-moving, evolving environment

Why Evozyne

  • Opportunity to drive multiple programs from candidate nomination through IND and into the clinic in a highly integrated, fast-moving environment
  • Ability to work at the intersection of AI, biology, and experimental science on problems where the path forward is not always clear
  • Significant ownership and influence on how preclinical programs are executed, prioritized, and scaled as the pipeline grows
  • Exposure to both strategic decisions and hands-on execution in a lean team where your work directly impacts program outcomes

Additional Information
Compensation Range: $175,000 - $250,000.

Individual compensation within this range is determined by a combination of factors, including but not limited to level, years of relevant job-related experience, and internal equity. This is what we believe in good faith is the range of possible base salary for this role at the time of this posting. We may ultimately pay more or less than the posted range. This range may be modified in the future.