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Toxicokinetics Jobs (NOW HIRING)

Arvinas

... toxicokinetics, drug metabolism, DME- and transporter-based DDI, 14C-ADME studies, QWBA, human PK prediction. This position reports to the Head of Nonclinical Sciences and may be based at our ...

Arvinas

DMPK Scientist

New Haven, CT · On-site +1

... toxicokinetics, drug metabolism, DME- and transporter-based DDI, 14C-ADME studies, QWBA, human PK prediction. This position reports to the Head of Nonclinical Sciences and may be based at our ...

Amgen

OR

Design, execute, and interpret results from in vivo studies characterizing pharmacokinetics, pharmacokinetic-pharmacodynamic relationships, tissue distribution, and toxicokinetics of antibody-siRNA ...

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Toxicokinetics information

What are the key skills and qualifications needed to thrive as a Toxicokinetics Scientist, and why are they important?

To thrive as a Toxicokinetics Scientist, you need a strong background in pharmacology, biochemistry, and mathematical modeling, often supported by an advanced degree in toxicology or a related field. Familiarity with analytical tools such as LC-MS/MS, pharmacokinetic modeling software (e.g., WinNonlin), and regulatory guidelines is typically required. Attention to detail, critical thinking, and clear communication are valuable soft skills for interpreting data and collaborating with multidisciplinary teams. These skills ensure accurate assessment of how chemicals interact with biological systems, which is crucial for drug development and safety evaluations.

What is the difference between Toxicokinetics vs Toxicology?

AspectToxicokineticsToxicology
FocusAbsorption, distribution, metabolism, and excretion of chemicalsAdverse effects of chemicals on biological systems
Required CredentialsDegree in toxicology, pharmacology, or related fieldsDegree in toxicology, pharmacology, or related fields
Work EnvironmentLaboratories, research facilities, industryLaboratories, research, regulatory agencies
Industry UsageRisk assessment, pharmacokinetic studiesHealth risk evaluation, safety testing

While Toxicokinetics focuses on how chemicals move through and are processed by the body, Toxicology examines the harmful effects chemicals can cause. Both fields often overlap but serve different purposes in chemical safety and health risk assessments.

How does a toxicokineticist typically collaborate with other scientists during a research project?

Toxicokineticists frequently work alongside toxicologists, pharmacologists, chemists, and data analysts to design experiments, interpret results, and ensure that the absorption, distribution, metabolism, and excretion (ADME) of substances are accurately assessed. Collaboration often involves regular meetings to discuss study design, share data, and align on regulatory requirements. Effective communication and teamwork are crucial, as toxicokinetic data directly inform safety assessments and risk evaluations, impacting both preclinical and clinical research outcomes.

What is toxicokinetics?

Toxicokinetics is the scientific study of how a chemical substance enters, moves through, and is eliminated from a living organism. It examines the absorption, distribution, metabolism, and excretion (ADME) of potentially toxic compounds. Understanding toxicokinetics helps scientists predict the concentration of chemicals in different tissues over time and assess potential health risks. This information is crucial for drug development, safety assessment, and regulatory decisions.
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Infographic showing various Toxicokinetics job openings in the United States as of May 2026, with employment types broken down into 100% Full Time. Highlights an 74% In-person, 13% Hybrid, and 13% Remote job distribution.

Scientific Account Management Liaison

RPM ReSearch

Exton, PA

$65K - $85K/yr

Full-time

Posted 29 days ago

Job description

Location: Greater Philadelphia Area, Pennsylvania

Title: Scientific Account Manager, Drug Development Services

Product or Service:

  • Drug development services for ADME, drug transporters, drug metabolism, pharmacokinetics, toxicokinetics, and/or bioanalytical method development

  • Bioanalysis Services and Study Design

  • Preclinical Toxicology Services and Study Design

Compensation mid-point: 75,000 Base with 15,000 in commission at plan

Full Benefits


Drug Development Account Manager

A preclinical Contract Research Organization located in the Greater Philadelphia Area, is seeking a candidate for an Account Manager representing a department that provides preclinical safety, efficacy, and PK testing services to pharmaceutical and medical device companies to support research and development. Account Managers (AMs) are key members of the Sales and Operations Team and function as liaisons between sponsors, internal research scientists, and business development team members. AMs use their knowledge of preclinical drug/device testing to design and manage studies for a wide range of sponsor requests ranging from lead optimization through regulatory submissions.

We are looking for a subject matter expert interested in a client-facing role to bring together the business development team, the scientific team, and the client.

Primary responsibilities:

∙ Designing studies that meet client sponsors’ needs in a scientifically sound and cost-effective manner

∙ Providing scientific consultative support for preclinical testing services, primarily ADME, drug transporters, drug metabolism, pharmacokinetics, toxicokinetics, and/or bioanalytical method development.

∙ Fostering account diversification and expansion in association with sales and marketing

∙ Remaining current on global regulatory requirements and industry trends related to drug and device development


Other important functions include:

∙ Managing client expectations with timely and relevant communications

∙ Participating in project management

∙ Coordinating internal research projects to optimize service offerings

∙ Interacting with different teams on a daily basis including scientists, upper management, vendors, legal, and accounting

∙ Maintaining accurate records in multiple internal databases


Candidate Requirements:

∙ A scientific background is a must. Working knowledge of pre-clinical research with a focus on drug transporters, drug metabolism, pharmacokinetics, toxicokinetics, and/or bioanalysis is highly desirable.

∙ Bachelor’s Degree in biology, life sciences, pharmacology, or chemistry. Master’s Degree or Ph.D. preferred.

∙ 3-5 years relevant industry experience depending on education level. 5 years BS, 3 years MS, 0 years Ph.D.

∙ Prior experience in a preclinical CRO is highly desirable, but not necessary

∙ Self-motivated individual with the ability to perform tasks independently with minimal supervision